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Volumn 16, Issue 6, 2014, Pages 739-747

Gene Replacement by Zinc Finger Nucleases in Medaka Embryos

Author keywords

Gene replacement; Gene targeting; gsdf; Homologous recombination; Zinc finger nuclease

Indexed keywords

EFFICIENCY; FINS (HEAT EXCHANGE); FISH; RNA; ZINC;

EID: 84911954873     PISSN: 14362228     EISSN: 14362236     Source Type: Journal    
DOI: 10.1007/s10126-014-9587-7     Document Type: Article
Times cited : (6)

References (54)
  • 1
    • 84862682521 scopus 로고    scopus 로고
    • Targeted disruption of exogenous EGFP gene in medaka using zinc-finger nucleases
    • PID: 22642582, COI: 1:CAS:528:DC%2BC38XosVGrtrY%3D
    • Ansai S, Ochiai H, Kanie Y, Kamei Y, Gou Y, Kitano T, Yamamoto T, Kinoshita M (2012) Targeted disruption of exogenous EGFP gene in medaka using zinc-finger nucleases. Dev Growth Differ 54:546–556. doi:10.1111/j.1440-169X.2012.01357.x
    • (2012) Dev Growth Differ , vol.54 , pp. 546-556
    • Ansai, S.1    Ochiai, H.2    Kanie, Y.3    Kamei, Y.4    Gou, Y.5    Kitano, T.6    Yamamoto, T.7    Kinoshita, M.8
  • 2
    • 84876447739 scopus 로고    scopus 로고
    • Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases
    • PID: 23288935, COI: 1:CAS:528:DC%2BC3sXhtVWnu73I
    • Ansai S, Sakuma T, Yamamoto T, Ariga H, Uemura N, Takahashi R, Kinoshita M (2013) Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases. Genetics 193:739–49. doi:10.1534/genetics.112.147645
    • (2013) Genetics , vol.193 , pp. 739-749
    • Ansai, S.1    Sakuma, T.2    Yamamoto, T.3    Ariga, H.4    Uemura, N.5    Takahashi, R.6    Kinoshita, M.7
  • 3
    • 80054962146 scopus 로고    scopus 로고
    • Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates
    • PID: 22028029, COI: 1:CAS:528:DC%2BC3MXhs12nt7fI
    • Ben J, Elworthy S, Ng AS, Van Eeden F, Ingham PW (2011) Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates. Development 138:4969–78. doi:10.1242/dev.070862
    • (2011) Development , vol.138 , pp. 4969-4978
    • Ben, J.1    Elworthy, S.2    Ng, A.S.3    Van Eeden, F.4    Ingham, P.W.5
  • 4
    • 58149374562 scopus 로고    scopus 로고
    • Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases
    • PID: 19064913, COI: 1:CAS:528:DC%2BD1cXhsFCltrvK
    • Beumer KJ, Trautman JK, Bozas A, Liu JL, Rutter J, Gall JG, Carroll D (2008) Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases. Proc Natl Acad Sci U S A 105:19821–6. doi:10.1073/pnas.0810475105 0810475105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19821-19826
    • Beumer, K.J.1    Trautman, J.K.2    Bozas, A.3    Liu, J.L.4    Rutter, J.5    Gall, J.G.6    Carroll, D.7
  • 5
    • 0034749283 scopus 로고    scopus 로고
    • Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
    • PID: 11113203, COI: 1:CAS:528:DC%2BD3MXptVSi
    • Bibikova M, Carroll D, Segal DJ, Trautman JK, Smith J, Kim YG, Chandrasegaran S (2001) Stimulation of homologous recombination through targeted cleavage by chimeric nucleases. Mol Cell Biol 21:289–297. doi:10.1128/Mcb.21.1.289-297.2001
    • (2001) Mol Cell Biol , vol.21 , pp. 289-297
    • Bibikova, M.1    Carroll, D.2    Segal, D.J.3    Trautman, J.K.4    Smith, J.5    Kim, Y.G.6    Chandrasegaran, S.7
  • 6
    • 0036021389 scopus 로고    scopus 로고
    • Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases
    • PID: 12136019, COI: 1:CAS:528:DC%2BD38XmsF2ru7c%3D
    • Bibikova M, Golic M, Golic KG, Carroll D (2002) Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. Genetics 161:1169–75
    • (2002) Genetics , vol.161 , pp. 1169-1175
    • Bibikova, M.1    Golic, M.2    Golic, K.G.3    Carroll, D.4
  • 7
    • 0037510038 scopus 로고    scopus 로고
    • Enhancing gene targeting with designed zinc finger nucleases
    • PID: 12730594, COI: 1:CAS:528:DC%2BD3sXksVymsrk%3D
    • Bibikova M, Beumer K, Trautman JK, Carroll D (2003) Enhancing gene targeting with designed zinc finger nucleases. Science 300:764–764. doi:10.1126/science.1079512
    • (2003) Science , vol.300 , pp. 764
    • Bibikova, M.1    Beumer, K.2    Trautman, J.K.3    Carroll, D.4
  • 8
    • 19544371373 scopus 로고    scopus 로고
    • Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century
    • PID: 15931173, COI: 1:CAS:528:DC%2BD2MXkslSmsro%3D
    • Capecchi MR (2005) Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat Rev Genet 6:507–12. doi:10.1038/nrg1619
    • (2005) Nat Rev Genet , vol.6 , pp. 507-512
    • Capecchi, M.R.1
  • 9
    • 78549267889 scopus 로고    scopus 로고
    • Targeted genome modification in mice using zinc-finger nucleases
    • PID: 20628038, COI: 1:CAS:528:DC%2BC3cXhsFOnt7rI
    • Carbery ID, Ji D, Harrington A, Brown V, Weinstein EJ, Liaw L, Cui XX (2010) Targeted genome modification in mice using zinc-finger nucleases. Genetics 186:451–U37. doi:10.1534/genetics.110.117002
    • (2010) Genetics , vol.186 , pp. 437-451
    • Carbery, I.D.1    Ji, D.2    Harrington, A.3    Brown, V.4    Weinstein, E.J.5    Liaw, L.6    Cui, X.X.7
  • 10
    • 80051535219 scopus 로고    scopus 로고
    • Genome engineering with zinc-finger nucleases
    • PID: 21828278, COI: 1:CAS:528:DC%2BC3MXhtF2qtrbI
    • Carroll D (2011) Genome engineering with zinc-finger nucleases. Genetics 188:773–82. doi:10.1534/genetics.111.131433
    • (2011) Genetics , vol.188 , pp. 773-782
    • Carroll, D.1
  • 11
    • 84867700973 scopus 로고    scopus 로고
    • Efficient detection, quantification and enrichment of subtle allelic alterations
    • PID: 23075543, COI: 1:CAS:528:DC%2BC38XhsFCgsLrF
    • Chen JB, Zhang X, Wang TS, Li ZD, Guan GJ, Hong YH (2012) Efficient detection, quantification and enrichment of subtle allelic alterations. DNA Res 19:423–433. doi:10.1093/dnares/dss023
    • (2012) DNA Res , vol.19 , pp. 423-433
    • Chen, J.B.1    Zhang, X.2    Wang, T.S.3    Li, Z.D.4    Guan, G.J.5    Hong, Y.H.6
  • 12
    • 78651322138 scopus 로고    scopus 로고
    • Targeted integration in rat and mouse embryos with zinc-finger nucleases
    • PID: 21151125, COI: 1:CAS:528:DC%2BC3cXhsFGgtrbN
    • Cui X, Ji D, Fisher DA, Wu Y, Briner DM, Weinstein EJ (2011) Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nat Biotechnol 29:64–7. doi:10.1038/nbt.1731 nbt.1731
    • (2011) Nat Biotechnol , vol.29 , pp. 64-67
    • Cui, X.1    Ji, D.2    Fisher, D.A.3    Wu, Y.4    Briner, D.M.5    Weinstein, E.J.6
  • 14
    • 32444448754 scopus 로고    scopus 로고
    • Homologous recombination in zebrafish ES cells
    • PID: 16475007, COI: 1:CAS:528:DC%2BD28XhtlSqtrg%3D
    • Fan L, Moon J, Crodian J, Collodi P (2006) Homologous recombination in zebrafish ES cells. Transgenic Res 15:21–30. doi:10.1007/s11248-005-3225-0
    • (2006) Transgenic Res , vol.15 , pp. 21-30
    • Fan, L.1    Moon, J.2    Crodian, J.3    Collodi, P.4
  • 19
    • 33846548626 scopus 로고    scopus 로고
    • Specification of primordial germ cells in medaka (Oryzias latipes)
    • PID: 17217535
    • Herpin A, Rohr S, Riedel D, Kluever N, Raz E, Schartl M (2007) Specification of primordial germ cells in medaka (Oryzias latipes). BMC Dev Biol 7:3. doi:10.1186/1471-213X-7-3
    • (2007) BMC Dev Biol , vol.7 , pp. 3
    • Herpin, A.1    Rohr, S.2    Riedel, D.3    Kluever, N.4    Raz, E.5    Schartl, M.6
  • 20
    • 0030294711 scopus 로고    scopus 로고
    • Pluripotency and differentiation of embryonic stem cell lines from the medakafish (Oryzias latipes)
    • PID: 9025059, COI: 1:CAS:528:DyaK28Xnt1Oitrc%3D
    • Hong Y, Winkler C, Schartl M (1996) Pluripotency and differentiation of embryonic stem cell lines from the medakafish (Oryzias latipes). Mech Dev 60:33–44
    • (1996) Mech Dev , vol.60 , pp. 33-44
    • Hong, Y.1    Winkler, C.2    Schartl, M.3
  • 21
    • 0032584234 scopus 로고    scopus 로고
    • Production of medakafish chimeras from a stable embryonic stem cell line
    • PID: 9520425, COI: 1:CAS:528:DyaK1cXitlKjtr0%3D
    • Hong Y, Winkler C, Schartl M (1998) Production of medakafish chimeras from a stable embryonic stem cell line. Proc Natl Acad Sci U S A 95:3679–84
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3679-3684
    • Hong, Y.1    Winkler, C.2    Schartl, M.3
  • 22
    • 2542635755 scopus 로고    scopus 로고
    • Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro
    • PID: 15141090, COI: 1:CAS:528:DC%2BD2cXkslCisb8%3D
    • Hong Y, Liu T, Zhao H, Xu H, Wang W, Liu R, Chen T, Deng J, Gui J (2004) Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro. Proc Natl Acad Sci U S A 101:8011–6. doi:10.1073/pnas.0308668101 0308668101
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8011-8016
    • Hong, Y.1    Liu, T.2    Zhao, H.3    Xu, H.4    Wang, W.5    Liu, R.6    Chen, T.7    Deng, J.8    Gui, J.9
  • 23
    • 77950599874 scopus 로고    scopus 로고
    • Accessibility of host cell lineages to medaka stem cells depends on genetic background and irradiation of recipient embryos
    • PID: 20238480, COI: 1:CAS:528:DC%2BC3cXivFaktbw%3D
    • Hong N, Li M, Zeng Z, Yi M, Deng J, Gui J, Winkler C, Schartl M, Hong Y (2010) Accessibility of host cell lineages to medaka stem cells depends on genetic background and irradiation of recipient embryos. Cell Mol Life Sci 67:1189–1202
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1189-1202
    • Hong, N.1    Li, M.2    Zeng, Z.3    Yi, M.4    Deng, J.5    Gui, J.6    Winkler, C.7    Schartl, M.8    Hong, Y.9
  • 24
    • 84874100970 scopus 로고    scopus 로고
    • Medaka embryonic stem cells are capable of generating entire organs and embryo-like miniatures
    • Hong N, He BP, Schartl M, Hong Y (2012) Medaka embryonic stem cells are capable of generating entire organs and embryo-like miniatures. Stem Cells Dev. doi:10.1089/scd.2012.0144
    • (2012) Stem Cells Dev
    • Hong, N.1    He, B.P.2    Schartl, M.3    Hong, Y.4
  • 25
    • 79961185942 scopus 로고    scopus 로고
    • Heritable gene targeting in zebrafish using customized TALENs
    • PID: 21822242
    • Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B (2011) Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol 29:699–700. doi:10.1038/nbt.1939
    • (2011) Nat Biotechnol , vol.29 , pp. 699-700
    • Huang, P.1    Xiao, A.2    Zhou, M.3    Zhu, Z.4    Lin, S.5    Zhang, B.6
  • 26
    • 0030032063 scopus 로고    scopus 로고
    • Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain
    • PID: 8577732, COI: 1:CAS:528:DyaK28Xptl2luw%3D%3D
    • Kim YG, Cha J, Chandrasegaran S (1996) Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc Natl Acad Sci U S A 93:1156–60
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1156-1160
    • Kim, Y.G.1    Cha, J.2    Chandrasegaran, S.3
  • 27
    • 33645315826 scopus 로고    scopus 로고
    • Time-lapse analysis reveals different modes of primordial germ cell migration in the medaka Oryzias latipes
    • PID: 16573738
    • Kurokawa H, Aoki Y, Nakamura S, Ebe Y, Kobayashi D, Tanaka M (2006) Time-lapse analysis reveals different modes of primordial germ cell migration in the medaka Oryzias latipes. Dev Growth Differ 48:209–21. doi:10.1111/j.1440-169X.2006.00858.x
    • (2006) Dev Growth Differ , vol.48 , pp. 209-221
    • Kurokawa, H.1    Aoki, Y.2    Nakamura, S.3    Ebe, Y.4    Kobayashi, D.5    Tanaka, M.6
  • 28
    • 67349115416 scopus 로고    scopus 로고
    • Medaka vasa is required for migration but not survival of primordial germ cells
    • PID: 19249358, COI: 1:CAS:528:DC%2BD1MXlslWqu7o%3D
    • Li M, Hong N, Xu H, Yi M, Li C, Gui J, Hong Y (2009) Medaka vasa is required for migration but not survival of primordial germ cells. Mech Dev 126:366–81. doi:10.1016/j.mod.2009.02.004
    • (2009) Mech Dev , vol.126 , pp. 366-381
    • Li, M.1    Hong, N.2    Xu, H.3    Yi, M.4    Li, C.5    Gui, J.6    Hong, Y.7
  • 29
    • 84874667545 scopus 로고    scopus 로고
    • Multiple regulatory regions control the transcription of medaka germ gene vasa
    • Li M, Guan G, Hong N, Hong Y (2012) Multiple regulatory regions control the transcription of medaka germ gene vasa. Biochimie. doi:10.1016/j.biochi.2012.12.003
    • (2012) Biochimie
    • Li, M.1    Guan, G.2    Hong, N.3    Hong, Y.4
  • 30
    • 84904754320 scopus 로고    scopus 로고
    • Formation and cultivation of medaka primordial germ cells
    • Li Z, Li M, Hong N, Yi M, Hong Y (2014) Formation and cultivation of medaka primordial germ cells. Cell Tissue Res. doi:10.1007/s00441-014-1867-z
    • (2014) Cell Tissue Res
    • Li, Z.1    Li, M.2    Hong, N.3    Yi, M.4    Hong, Y.5
  • 31
    • 0026907094 scopus 로고
    • Integration, expression and germ-line transmission of foreign growth hormone genes in medaka (Oryzias latipes)
    • Lu, J.K., Chen, T.T., Chrisman, C.L., Andrisani, O.M. & Dixon, J.E. (1992). Integration, expression and germ-line transmission of foreign growth hormone genes in medaka (Oryzias latipes). Mol Mar Biol Biotechnol 1:366–75
    • (1992) Mol Mar Biol Biotechnol , vol.1 , pp. 366-375
    • Lu, J.K.1    Chen, T.T.2    Chrisman, C.L.3    Andrisani, O.M.4    Dixon, J.E.5
  • 33
    • 44949162060 scopus 로고    scopus 로고
    • Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
    • PID: 18500337, COI: 1:CAS:528:DC%2BD1cXmvVCju7o%3D
    • Meng XD, Noyes MB, Zhu LHJ, Lawson ND, Wolfe SA (2008) Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat Biotechnol 26:695–701. doi:10.1038/Nbt1398
    • (2008) Nat Biotechnol , vol.26 , pp. 695-701
    • Meng, X.D.1    Noyes, M.B.2    Zhu, L.H.J.3    Lawson, N.D.4    Wolfe, S.A.5
  • 34
    • 77957005768 scopus 로고    scopus 로고
    • Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases
    • PID: 20686113, COI: 1:CAS:528:DC%2BC3cXhtFSmt7vP
    • Meyer M, De Angelis MH, Wurst W, Kuhn R (2010) Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases. Proc Natl Acad Sci U S A 107:15022–6. doi:10.1073/pnas.1009424107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15022-15026
    • Meyer, M.1    De Angelis, M.H.2    Wurst, W.3    Kuhn, R.4
  • 35
    • 77954738991 scopus 로고    scopus 로고
    • Targeted mutagenesis in the sea urchin embryo using zinc-finger nucleases
    • PID: 20604805, COI: 1:CAS:528:DC%2BC3cXhtVCltbrO
    • Ochiai H, Fujita K, Suzuki K, Nishikawa M, Shibata T, Sakamoto N, Yamamoto T (2010) Targeted mutagenesis in the sea urchin embryo using zinc-finger nucleases. Genes Cells 15:875–885. doi:10.1111/j.1365-2443.2010.01425.x
    • (2010) Genes Cells , vol.15 , pp. 875-885
    • Ochiai, H.1    Fujita, K.2    Suzuki, K.3    Nishikawa, M.4    Shibata, T.5    Sakamoto, N.6    Yamamoto, T.7
  • 36
    • 0020645054 scopus 로고
    • One-step gene disruption in yeast
    • PID: 6310324, COI: 1:CAS:528:DyaL2cXhvVOmsA%3D%3D
    • Rothstein RJ (1983) One-step gene disruption in yeast. Methods Enzymol 101:202–11
    • (1983) Methods Enzymol , vol.101 , pp. 202-211
    • Rothstein, R.J.1
  • 37
    • 79961192836 scopus 로고    scopus 로고
    • Targeted gene disruption in somatic zebrafish cells using engineered TALENs
    • PID: 21822241, COI: 1:CAS:528:DC%2BC3MXpvVOlsrc%3D
    • Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR (2011) Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat Biotechnol 29:697–8. doi:10.1038/nbt.1934
    • (2011) Nat Biotechnol , vol.29 , pp. 697-698
    • Sander, J.D.1    Cade, L.2    Khayter, C.3    Reyon, D.4    Peterson, R.T.5    Joung, J.K.6    Yeh, J.R.7
  • 38
    • 78650852409 scopus 로고    scopus 로고
    • Expression of gonadal soma derived factor (GSDF) is spatially and temporally correlated with early testicular differentiation in medaka
    • PID: 20601164, COI: 1:CAS:528:DC%2BC3cXpt12mtb0%3D
    • Shibata Y, Paul-Prasanth B, Suzuki A, Usami T, Nakamoto M, Matsuda M, Nagahama Y (2010) Expression of gonadal soma derived factor (GSDF) is spatially and temporally correlated with early testicular differentiation in medaka. Gene Expr Patterns 10:283–289. doi:10.1016/j.gep.2010.06.005
    • (2010) Gene Expr Patterns , vol.10 , pp. 283-289
    • Shibata, Y.1    Paul-Prasanth, B.2    Suzuki, A.3    Usami, T.4    Nakamoto, M.5    Matsuda, M.6    Nagahama, Y.7
  • 39
    • 0023884698 scopus 로고
    • Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos
    • Stuart, G.W., McMurray, J.V. & Westerfield, M. (1988). Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Dev 103:403–12
    • (1988) Dev , vol.103 , pp. 403-412
    • Stuart, G.W.1    McMurray, J.V.2    Westerfield, M.3
  • 41
    • 0035956930 scopus 로고    scopus 로고
    • Establishment of medaka (Oryzias latipes) transgenic lines with the expression of green fluorescent protein fluorescence exclusively in germ cells: a useful model to monitor germ cells in a live vertebrate
    • PID: 11226275, COI: 1:CAS:528:DC%2BD3MXhslKms7k%3D
    • Tanaka M, Kinoshita M, Kobayashi D, Nagahama Y (2001) Establishment of medaka (Oryzias latipes) transgenic lines with the expression of green fluorescent protein fluorescence exclusively in germ cells: a useful model to monitor germ cells in a live vertebrate. Proc Natl Acad Sci U S A 98:2544–9. doi:10.1073/pnas.041315498
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2544-2549
    • Tanaka, M.1    Kinoshita, M.2    Kobayashi, D.3    Nagahama, Y.4
  • 42
    • 77956524118 scopus 로고    scopus 로고
    • Production of p53 gene knockout rats by homologous recombination in embryonic stem cells
    • PID: 20703227, COI: 1:CAS:528:DC%2BC3cXhtVSmurnO
    • Tong C, Li P, Wu NL, Yan Y, Ying QL (2010) Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature 467:211–3. doi:10.1038/nature09368
    • (2010) Nature , vol.467 , pp. 211-213
    • Tong, C.1    Li, P.2    Wu, N.L.3    Yan, Y.4    Ying, Q.L.5
  • 43
    • 0001782331 scopus 로고    scopus 로고
    • Transgenic livestock: progress and prospects for the future
    • Wall R.J. (1996). Transgenic livestock: progress and prospects for the future. Theriologenology 45:57–68
    • (1996) Theriologenology , vol.45 , pp. 57-68
    • Wall, R.J.1
  • 45
    • 0036245348 scopus 로고    scopus 로고
    • Medaka—a model organism from the far East
    • PID: 11823791, COI: 1:CAS:528:DC%2BD38XhsV2gtrg%3D
    • Wittbrodt J, Shima A, Schartl M (2002) Medaka—a model organism from the far East. Nat Rev Genet 3:53–64
    • (2002) Nat Rev Genet , vol.3 , pp. 53-64
    • Wittbrodt, J.1    Shima, A.2    Schartl, M.3
  • 48
    • 70350128134 scopus 로고    scopus 로고
    • Generation of medaka fish haploid embryonic stem cells
    • PID: 19833967, COI: 1:CAS:528:DC%2BD1MXht1GgtLfI
    • Yi M, Hong N, Hong Y (2009) Generation of medaka fish haploid embryonic stem cells. Science 326:430–3. doi:10.1126/science.1175151
    • (2009) Science , vol.326 , pp. 430-433
    • Yi, M.1    Hong, N.2    Hong, Y.3
  • 49
    • 77955183842 scopus 로고    scopus 로고
    • Derivation and characterization of haploid embryonic stem cell cultures in medaka fish
    • PID: 20671725, COI: 1:CAS:528:DC%2BC3cXpsVCksL0%3D
    • Yi M, Hong N, Hong Y (2010) Derivation and characterization of haploid embryonic stem cell cultures in medaka fish. Nat Protoc 5:1418–30. doi:10.1038/nprot.2010.104
    • (2010) Nat Protoc , vol.5 , pp. 1418-1430
    • Yi, M.1    Hong, N.2    Hong, Y.3
  • 51
    • 84894323293 scopus 로고    scopus 로고
    • Parameters and efficiency of direct gene disruption by zinc finger nucleases in Medaka embryos
    • Zhang X, Guan G, Chen J, Naruse K, Hong Y (2013) Parameters and efficiency of direct gene disruption by zinc finger nucleases in Medaka embryos. Marine Biotechnol. doi:10.1007/s10126-013-9556-6
    • (2013) Marine Biotechnol
    • Zhang, X.1    Guan, G.2    Chen, J.3    Naruse, K.4    Hong, Y.5
  • 52
    • 84862910017 scopus 로고    scopus 로고
    • Fusion gene vectors allowing for simultaneous drug selection, cell labeling and reporter assay in vitro and in vivo
    • Zhao H, Hong N, Lu W, Zeng H, Song J, Hong Y (2011) Fusion gene vectors allowing for simultaneous drug selection, cell labeling and reporter assay in vitro and in vivo. Anal Chem. doi:10.1021/ac202541t
    • (2011) Anal Chem
    • Zhao, H.1    Hong, N.2    Lu, W.3    Zeng, H.4    Song, J.5    Hong, Y.6
  • 53
    • 84862910017 scopus 로고    scopus 로고
    • Fusion gene vectors allowing for simultaneous drug selection, cell labeling, and reporter assay in vitro and in vivo
    • PID: 22081858, COI: 1:CAS:528:DC%2BC3MXhsVKiur%2FE
    • Zhao H, Hong N, Lu W, Zeng H, Song J, Hong Y (2012) Fusion gene vectors allowing for simultaneous drug selection, cell labeling, and reporter assay in vitro and in vivo. Anal Chem 84:987–93. doi:10.1021/ac202541t
    • (2012) Anal Chem , vol.84 , pp. 987-993
    • Zhao, H.1    Hong, N.2    Lu, W.3    Zeng, H.4    Song, J.5    Hong, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.