Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32639-32655

  Bing, Yuntao ^a   Zhu, Siying ^a   Yu, Guozheng ^a   Li, Ting ^a   Liu, Weijun ^a   Li, Changsheng ^a   Wang, Yitao ^a   Qi, Haolong ^a   Guo, Tao ^a   Yuan, Yufeng ^a   He, Yueming ^a   Liu, Zhisu ^a   Liu, Quanyan ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINO ACIDS; ANTIBIOTICS; FEEDBACK; GLYCOPROTEINS; HORMONES; METHYLATION; PATIENT TREATMENT; PROTEINS; VIRUSES;

ANTIVIRAL ACTIVITIES; CHRONIC HEPATITIS B; DNA METHYLTRANSFERASES; GLUCOCORTICOID RECEPTOR; POSITIVE FEEDBACK LOOP; POSSIBLE MECHANISMS; POST-TRANSCRIPTIONAL REGULATIONS; S-ADENOSYLMETHIONINE;

CELL SIGNALING;

ALPHA INTERFERON; DEXAMETHASONE; DNA METHYLTRANSFERASE 1; GLUCOCORTICOID RECEPTOR; HEPATITIS B VIRUS X PROTEIN; METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE 1A; S ADENOSYLMETHIONINE; STAT1 PROTEIN; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; GLUCOCORTICOID; MAT1A PROTEIN, HUMAN; PROTEIN BINDING;

AMINO ACID SYNTHESIS; ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA FLANKING REGION; DNA SEQUENCE; DRUG PROTEIN BINDING; GENE; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION REGULATION; GENE LOCATION; GLUCOCORTICOID RESPONSIVE ELEMENT; HEPATITIS B; HEPATITIS B VIRUS; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; IN VITRO STUDY; LUCIFERASE ASSAY; MAT1A GENE; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; POSITIVE FEEDBACK; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION; VIRUS REPLICATION; CELL LINE; DNA METHYLATION; DNA RESPONSIVE ELEMENT; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEPG2 CELL LINE; IMMUNOBLOTTING; METABOLISM; METHYLATION; PHYSIOLOGY; TUMOR CELL LINE;

HEPATITIS B VIRUS;

ANTIVIRAL AGENTS; CELL LINE; CELL LINE, TUMOR; DEXAMETHASONE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENE EXPRESSION; GLUCOCORTICOIDS; HEP G2 CELLS; HEPATITIS B VIRUS; HUMANS; IMMUNOBLOTTING; INTERFERON-ALPHA; METHIONINE ADENOSYLTRANSFERASE; METHYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; S-ADENOSYLMETHIONINE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR;

EID: 84911948657     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.589689     Document Type: Article

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