Bayesian inference supports a location and neighbour-dependent model of DNA methylation propagation at the MGMT gene promoter in lung tumours

Journal of Theoretical Biology

Volumn 336, Issue , 2013, Pages 87-95

  Bonello, Nicolas ^a   Sampson, James ^b   Burn, John ^b   Wilson, Ian J ^b   McGrown, Gail ^c   Margison, Geoff P ^c   Thorncroft, Mary ^c   Crossbie, Philip ^d   Povey, Andrew C ^d   Santibanez Koref, Mauro ^b   Walters, Kevin ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Bayesian analysis; DNA methylation; Lung cancer; MGMT; Model selection

Indexed keywords

DNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

BAYESIAN ANALYSIS; CANCER; DNA; METHYLATION; NUMERICAL MODEL; TUMOR;

ALLELE; ARTICLE; BAYES THEOREM; COMPARATIVE STUDY; CPG ISLAND; DNA METHYLATION; EXON; GENETIC POLYMORPHISM; LUNG TUMOR; MGMT GENE; PRIORITY JOURNAL; PROBABILITY; PROMOTER REGION; SIMULATION; STATISTICAL MODEL; BIOLOGICAL MODEL; ENZYMOLOGY; GENETIC DATABASE; GENETICS; HUMAN;

ALLELES; BAYES THEOREM; CPG ISLANDS; DATABASES, GENETIC; DNA METHYLATION; HUMANS; LUNG NEOPLASMS; MODELS, GENETIC; MODELS, STATISTICAL; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PROMOTER REGIONS, GENETIC;

EID: 84882257623     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2013.07.019     Document Type: Article

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