Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 2, 2014, Pages 107-116

  Baena, Miguel ^a   Sangüesa, Gemma ^a   Hutter, Natalia ^a   Sánchez, Rosa M ^a,b   Roglans, Núria ^a,b   Laguna, Juan C ^a,b   Alegret, Marta ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

Autophagy; Fructose; Hepatic steatosis; mTORC

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACTIVATING TRANSCRIPTION FACTOR 6; ACYL COENZYME A DESATURASE; ADENYLATE KINASE; FATTY ACID; FRUCTOSE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCOGEN SYNTHASE KINASE 3BETA; HEPATOCYTE NUCLEAR FACTOR 4; JANUS KINASE 1; MAMMALIAN TARGET OF RAPAMYCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN IRE1; PROTEIN KINASE B; PROTEIN P62; SIRTUIN 1; TRIACYLGLYCEROL; TUBULIN; MTOR PROTEIN, RAT; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; FATTY LIVER; FEMALE; GENE EXPRESSION; HISTOLOGY; HYPERTRIGLYCERIDEMIA; LIPID OXIDATION; LIPID STORAGE; LIPOGENESIS; LIVER; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; GLYCOLYSIS; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; PENTOSE PHOSPHATE CYCLE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TIME;

RATTUS;

ANIMALS; AUTOPHAGY; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FATTY ACIDS; FATTY LIVER; FEMALE; FRUCTOSE; GENE EXPRESSION REGULATION; GLYCOLYSIS; HYPERTRIGLYCERIDEMIA; LIPOGENESIS; LIVER; OXIDATION-REDUCTION; PENTOSE PHOSPHATE PATHWAY; PHOSPHORYLATION; PPAR ALPHA; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES; TRIGLYCERIDES;

EID: 84911933228     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.11.003     Document Type: Article

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