Depressed mitochondrial biogenesis and dynamic remodeling in mouse tibialis anterior and gastrocnemius induced by 4-week hindlimb unloading

IUBMB Life

Volumn 64, Issue 11, 2012, Pages 901-910

  Liu, Jing ^a   Peng, Yunhua ^a   Cui, Zhiwei ^a   Wu, Zhiming ^a   Qian, Airong ^b   Shang, Peng ^b   Qu, Lina ^c   Li, Yinghui ^c   Liu, Jiankang ^a   Long, Jiangang ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

^c CHINA ASTRONAUT RESEARCH AND TRAINING CENTER   (China)

Author keywords

mitochondria dynamics remodeling; skeletal muscle atrophy; unloading

Indexed keywords

ADENYLATE KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BIOGENESIS; CONTROLLED STUDY; DEPRESSED MITOCHONDRIAL BIOGENESIS; EXPERIMENTAL MODEL; GASTROCNEMIUS MUSCLE; HINDLIMB UNLOADING; MALE; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL RESPIRATION; MOLECULAR DYNAMICS; MOUSE; MUSCLE ATROPHY; MUSCLE MITOCHONDRION; NONHUMAN; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; TIBIALIS ANTERIOR MUSCLE;

ANIMALS; BLOTTING, WESTERN; HINDLIMB SUSPENSION; MALE; MICE; MICE, INBRED STRAINS; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL TURNOVER; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PHYSICAL CONDITIONING, ANIMAL; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84867838766     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1087     Document Type: Article

References (36)

1. Jackman, R. W., and, Kandarian, S. C., (2004) The molecular basis of skeletal muscle atrophy. Am. J. Physiol. Cell Physiol. 287, C834.
2. McKinnell, I. W., and, Rudnicki, M. A., (2004) Molecular mechanisms of muscle atrophy. Cell 119, 907-910.
3. Morey, E. R., (1979) Spaceflight and bone turnover: correlation with a new rat model of weightlessness. Bioscience 29, 168-172.
4. Morey-Holton, E. R., and, Globus, R. K., (2002) Hindlimb unloading rodent model: technical aspects. J. Appl. Physiol. 92, 1367.
5. Hock, M. B., and, Kralli, A., (2009) Transcriptional control of mitochondrial biogenesis and function. Annu. Rev. Physiol. 71, 177-203.
6. Powers, S. K., Kavazis, A. N., and, McClung, J. M., (2007) Oxidative stress and disuse muscle atrophy. J. Appl. Physiol. 102, 2389.
7. Marzetti, E., Hwang, J. C. Y., Lees, H. A., Wohlgemuth, S. E., Dupont-Versteegden, E. E., et al. (2010) Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy. Biochim. Biophys. Acta (BBA)-Gen. Subj. 1800, 235-244.
8. Scarpulla, R. C., (2008) Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev. 88, 611.
9. Vega, R. B., Huss, J. M., and, Kelly, D. P., (2000) The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol. Cell Biol. 20, 1868.
10. Sugden, M. C., Caton, P. W., and, Holness, M. J., (2010) PPAR control: it's SIRTainly as easy as PGC. J. Endocrinol. 204, 93.
11. Roberts-Wilson, T. K., Reddy, R. N., Bailey, J. L., Zheng, B., Ordas, R., et al. (2010) Calcineurin signaling and PGC-1 [alpha] expression are suppressed during muscle atrophy due to diabetes. Biochim. Biophys. Acta (BBA)-Mol. Cell Res. 1803, 960-967.
12. Mazzatti, D. J., Smith, M. A., Oita, R. C., Lim, F. L., White, A. J., et al. (2008) Muscle unloading-induced metabolic remodeling is associated with acute alterations in PPARÎ and UCP-3 expression. Physiol. Genom. 34, 149-161.
13. Sandri, M., Lin, J., Handschin, C., Yang, W., Arany, Z. P., et al.(2006) PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc. Natl. Acad. Sci. USA 103, 16260.
14. Tatsuta, T., and, Langer, T., (2008) Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J. 27, 306-314.
15. Romanello, V., Guadagnin, E., Gomes, L., Roder, I., Sandri, C., et al. (2010) Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J. 29, 1774-1785.
16. Masiero, E., Agatea, L., Mammucari, C., Blaauw, B., Loro, E., et al. (2009) Autophagy is required to maintain muscle mass. Cell Metabol. 10, 507-515.
17. Thomason, D. B., and, Booth, F. W., (1990) Atrophy of the soleus muscle by hindlimb unweighting. J. Appl. Physiol. 68, 1.
18. Cassano, P., Sciancalepore, A., Pesce, V., Flück, M., Hoppeler, H., et al. (2006) Acetyl- L -carnitine feeding to unloaded rats triggers in soleus muscle the coordinated expression of genes involved in mitochondrial biogenesis. Biochim. Biophys. Acta (BBA)-Bioenerg. 1757, 1421-1428.
19. Koesterer, T., Dodd, S. L., and, Powers, S., (2002) Increased antioxidant capacity does not attenuate muscle atrophy caused by unweighting. J. Appl. Physiol. 93, 1959.
20. Desaphy, J. F., Pierno, S., Liantonio, A., Giannuzzi, V., Digennaro, C., et al. (2010) Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles. Pharmacol. Res. 61, 553-563.
21. Yajid, F., Mercier, J. G., Mercier, B. M., Dubouchaud, H., and, Préfaut C,.(1998) Effects of 4 wk of hindlimb suspension on skeletal muscle mitochondrial respiration in rats. J. Appl. Physiol. 84, 479.
22. Ohira, Y., Nomura, T., Kawano, F., Sato, Y., Ishihara, A., et al. (2002) Effects of nine weeks of unloading on neuromuscular activities in adult rats. J. Gravit. Physiol. 9, 49.
23. Ferreira, J. A., Crissey, J. M., and, Brown, M., (2011) An alternant method to the traditional NASA hindlimb unloading model in mice. J. Vis. Exp. 49, e2467.
24. Long, J., Wang, X., Gao, H., Liu, Z., Liu, C., et al. (2007) D-galactose toxicity in mice is associated with mitochondrial dysfunction: protecting effects of mitochondrial nutrient R-alpha-lipoic acid. Biogerontology 8, 373-381.
25. Shen, W., Liu, K., Tian, C., Yang, L., Li, X., et al. (2008) R-α-Lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes. Diabetologia 51, 165-174.
26. Ryan, M. T., and, Hoogenraad, N. J., (2007) Mitochondrial-nuclear communications. Annu. Rev. Biochem. 76, 701-722.
27. Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., et al. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829.
28. Lira, V. A., Brown, D. L., Lira, A. K., Kavazis, A. N., Soltow, Q. A., et al. (2010) Nitric oxide and AMPK cooperatively regulate PGC-1α in skeletal muscle cells. J. Physiol. 588, 3551.
29. Gurd, B. J., (2011) Deacetylation of PGC-1α by SIRT1: importance for skeletal muscle function and exercise-induced mitochondrial biogenesis. Appl. Physiol. Nutr. Metabol. 36, 589-597.
30. Han, B., Zhu, M. J., Ma, C., and, Du, M., (2007) Rat hindlimb unloading down-regulates insulin like growth factor-1 signaling and AMP-activated protein kinase, and leads to severe atrophy of the soleus muscle. Appl. Physiol. Nutr. Metabol. 32, 1115-1123.
31. Vives-Bauza, C., Zhou, C., Huang, Y., Cui, M., de Vries, R. L. A., et al. (2010) PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc. Natl. Acad. Sci. USA 107, 378.
32. Schweers, R. L., Zhang, J., Randall, M. S., Loyd, M. R., Li, W., et al. (2007) NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc. Natl. Acad. Sci. USA 104, 19500.
33. Wang, X., Su, B., Lee, H., Li, X., Perry, G., et al. (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J. Neurosci. 29, 9090-9103.
34. Song, Z., Ghochani, M., McCaffery, J. M., Frey, T. G., and, Chan, D. C., (2009) Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion. Mol. Biol. Cell 20, 3525-3532.
35. Wagatsuma, A., Kotake, N., Kawachi, T., Shiozuka, M., Yamada, S., et al. (2010) Mitochondrial adaptations in skeletal muscle to hindlimb unloading. Mol. Cell Biochem. 350, 1-11.
36. Twig, G., Hyde, B., and, Shirihai, O. S., (2008) Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim. Biophys. Acta Bioenerg. 1777, 1092-1097.