Targeted reduction of vascular Msx1 and Msx2 mitigates arteriosclerotic calcification and aortic stiffness in LDLR-deficient mice fed diabetogenic diets

Diabetes

Volumn 63, Issue 12, 2014, Pages 4326-4337

  Cheng, Su Li ^a   Behrmann, Abraham ^a   Shao, Jian Su ^b   Ramachandran, Bindu ^a   Krchma, Karen ^a   Arredondo, Yoanna Bello ^a   Kovacs, Attila ^c   Mead, Megan ^a   Maxson, Robert ^d   Towler, Dwight A ^a,e  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c WASHINGTON UNIVERSITY   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e FLORIDA HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ATAXIN 1; DEXAMETHASONE; GLUCOSE; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR MSX2; WNT11 PROTEIN; WNT2 PROTEIN; WNT3 PROTEIN; WNT4 PROTEIN; WNT5A PROTEIN; WNT5B PROTEIN; WNT7A PROTEIN; WNT7B PROTEIN; WNT8B PROTEIN; WNT9A PROTEIN; HOMEODOMAIN PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LY ANTIGEN; LY6A PROTEIN, MOUSE; MEMBRANE PROTEIN; MSX1 PROTEIN, MOUSE; SHH PROTEIN, MOUSE; WNT PROTEIN; WNT5A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL STIFFNESS; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD VESSEL DIAMETER; BONE MINERAL; CONTROLLED STUDY; DIABETIC ANGIOPATHY; DIABETOGENIC DIET; DOPPLER ECHOCARDIOGRAPHY; DOWN REGULATION; DUAL ENERGY X RAY ABSORPTIOMETRY; GENE DELETION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; LIPID DIET; MALE; MESENCHYME CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; OBESITY; PRIMARY CELL CULTURE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PULSE WAVE; RNA INTERFERENCE; SMOOTH MUSCLE FIBER; ANIMAL; AORTA; ARTERIOSCLEROSIS; BLOOD VESSEL CALCIFICATION; BONE DEVELOPMENT; CELL CULTURE; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION PROFILING; GENETICS; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; ANTIGENS, LY; AORTA; ARTERIOSCLEROSIS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIET, HIGH-FAT; GENE DELETION; GENE EXPRESSION PROFILING; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MSX1 TRANSCRIPTION FACTOR; MYOCYTES, SMOOTH MUSCLE; MYOFIBROBLASTS; OSTEOGENESIS; RECEPTORS, LDL; VASCULAR CALCIFICATION; VASCULAR STIFFNESS; WNT PROTEINS; WNT2 PROTEIN;

EID: 84911877386     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0326     Document Type: Article

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