-
1
-
-
0036561908
-
Modelling the molecular circuitry of cancer
-
Hahn WC, Weinberg RA. Modelling the molecular circuitry of cancer. Nat Rev Cancer 2002; 2: 331-41.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 331-341
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
2
-
-
61449182121
-
Principles of cancer therapy: Oncogene and non-oncogene addiction
-
Luo J, Solimini NL, Elledge SJ. Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 2009; 136: 823-37.
-
(2009)
Cell
, vol.136
, pp. 823-837
-
-
Luo, J.1
Solimini, N.L.2
Elledge, S.J.3
-
3
-
-
0037025173
-
Cancer. Addiction to oncogenes--the Achilles heal of cancer
-
Weinstein IB. Cancer. Addiction to oncogenes--the Achilles heal of cancer. Science 2002; 297: 63-4.
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
-
4
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher DW, Bishop JM. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 1999; 4: 199-207.
-
(1999)
Mol Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
5
-
-
0037025201
-
Sustained loss of a neoplastic phenotype by brief inactivation of MYC
-
Jain M, Arvanitis C, Chu K, et al. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 2002; 297: 102-4.
-
(2002)
Science
, vol.297
, pp. 102-104
-
-
Jain, M.1
Arvanitis, C.2
Chu, K.3
-
6
-
-
0037013147
-
Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
-
Pelengaris S, Khan M, Evan GI. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell 2002; 109: 321-34.
-
(2002)
Cell
, vol.109
, pp. 321-334
-
-
Pelengaris, S.1
Khan, M.2
Evan, G.I.3
-
7
-
-
0036781812
-
c-MYC: More than just a matter of life and death
-
Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer 2002; 2: 764-76.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 764-776
-
-
Pelengaris, S.1
Khan, M.2
Evan, G.3
-
8
-
-
79952833775
-
MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms
-
Felsher DW. MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms. Genes Cancer 2010; 1: 597-604.
-
(2010)
Genes Cancer
, vol.1
, pp. 597-604
-
-
Felsher, D.W.1
-
9
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker BJ, Lydon NB. Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J Clin Invest 2000; 105: 3-7.
-
(2000)
J Clin Invest
, vol.105
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
10
-
-
0038777142
-
Imatinib: A targeted clinical drug development
-
Capdeville R, Silberman S. Imatinib: a targeted clinical drug development. Semin Hematol 2003; 40: 15-20.
-
(2003)
Semin Hematol
, vol.40
, pp. 15-20
-
-
Capdeville, R.1
Silberman, S.2
-
11
-
-
0036653768
-
Targeting epidermal growth factor receptor in lung cancer
-
Baselga J, Albanell J. Targeting epidermal growth factor receptor in lung cancer. Curr Oncol Rep 2002; 4: 317-24.
-
(2002)
Curr Oncol Rep
, vol.4
, pp. 317-324
-
-
Baselga, J.1
Albanell, J.2
-
12
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
Vita M, Henriksson M. The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 2006; 16: 318-30.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
14
-
-
84862731787
-
Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis
-
Huang HL, Weng HY, Wang LQ, et al. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis. Mol Cancer Ther 2012; 11: 1155-65.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1155-1165
-
-
Huang, H.L.1
Weng, H.Y.2
Wang, L.Q.3
-
15
-
-
77952266182
-
Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells
-
Lu JJ, Meng LH, Shankavaram UT, et al. Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells. Biochem Pharmacol 2010; 80: 22-30.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 22-30
-
-
Lu, J.J.1
Meng, L.H.2
Shankavaram, U.T.3
-
16
-
-
0020349364
-
Retroviruses and cancer genes
-
Bishop JM. Retroviruses and cancer genes. Adv Cancer Res 1982; 37: 1-32.
-
(1982)
Adv Cancer Res
, vol.37
, pp. 1-32
-
-
Bishop, J.M.1
-
17
-
-
0020603359
-
The human c-myc oncogene: Structural consequences of translocation into the IgH locus in Burkitt lymphoma
-
Battey J, Moulding C, Taub R, et al. The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma. Cell 1983; 34: 779-87.
-
(1983)
Cell
, vol.34
, pp. 779-787
-
-
Battey, J.1
Moulding, C.2
Taub, R.3
-
18
-
-
0026774149
-
Translational activation of the non-AUG-initiated c-myc 1 protein at high cell densities due to methionine deprivation
-
Hann SR, Sloan-Brown K, Spotts GD. Translational activation of the non-AUG-initiated c-myc 1 protein at high cell densities due to methionine deprivation. Genes Dev 1992; 6: 1229-40.
-
(1992)
Genes Dev
, vol.6
, pp. 1229-1240
-
-
Hann, S.R.1
Sloan-Brown, K.2
Spotts, G.D.3
-
19
-
-
58149098874
-
Specific targeting of HER2 overexpressing breast cancer cells with doxorubicin-loaded trastuzumab-modified human serum albumin nanoparticles
-
Anhorn MG, Wagner S, Kreuter J, Langer K, von Briesen H. Specific targeting of HER2 overexpressing breast cancer cells with doxorubicin-loaded trastuzumab-modified human serum albumin nanoparticles. Bioconjug Chem 2008; 19: 2321-31.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 2321-2331
-
-
Anhorn, M.G.1
Wagner, S.2
Kreuter, J.3
Langer, K.4
von Briesen, H.5
-
20
-
-
0031037987
-
Identification of downstream-initiated c-Myc proteins which are dominant-negative inhibitors of transactivation by full-length c-Myc proteins
-
Spotts GD, Patel SV, Xiao Q, Hann SR. Identification of downstream-initiated c-Myc proteins which are dominant-negative inhibitors of transactivation by full-length c-Myc proteins. Mol Cell Biol 1997; 17: 1459-68.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1459-1468
-
-
Spotts, G.D.1
Patel, S.V.2
Xiao, Q.3
Hann, S.R.4
-
21
-
-
0025763419
-
Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
-
Blackwood EM, Eisenman RN. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 1991; 251: 1211-7.
-
(1991)
Science
, vol.251
, pp. 1211-1217
-
-
Blackwood, E.M.1
Eisenman, R.N.2
-
22
-
-
0025829169
-
Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation
-
Prendergast GC, Lawe D, Ziff EB. Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell 1991; 65: 395-407.
-
(1991)
Cell
, vol.65
, pp. 395-407
-
-
Prendergast, G.C.1
Lawe, D.2
Ziff, E.B.3
-
23
-
-
0025608909
-
Sequence-specific DNA binding by the c-Myc protein
-
Blackwell TK, Kretzner L, Blackwood EM, Eisenman RN and Weintraub H. Sequence-specific DNA binding by the c-Myc protein. Science 1990; 250: 1149-51.
-
(1990)
Science
, vol.250
, pp. 1149-1151
-
-
Blackwell, T.K.1
Kretzner, L.2
Blackwood, E.M.3
Eisenman, R.N.4
Weintraub, H.5
-
24
-
-
0026665523
-
Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max
-
Amati B, Dalton S, Brooks MW, Littlewood TD, Evan GI, Land H. Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature 1992; 359: 423-6.
-
(1992)
Nature
, vol.359
, pp. 423-426
-
-
Amati, B.1
Dalton, S.2
Brooks, M.W.3
Littlewood, T.D.4
Evan, G.I.5
Land, H.6
-
25
-
-
0033551393
-
The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: Function and regulation
-
Luscher B, Larsson LG. The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: function and regulation. Oncogene 1999; 18: 2955-66.
-
(1999)
Oncogene
, vol.18
, pp. 2955-2966
-
-
Luscher, B.1
Larsson, L.G.2
-
26
-
-
0025166030
-
An amino-terminal c-myc domain required for neoplastic transformation activates transcription
-
Kato GJ, Barrett J, Villa-Garcia M, Dang CV. An amino-terminal c-myc domain required for neoplastic transformation activates transcription. Mol Cell Biol 1990; 10: 5914-20.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 5914-5920
-
-
Kato, G.J.1
Barrett, J.2
Villa-Garcia, M.3
Dang, C.V.4
-
27
-
-
0023116071
-
Definition of regions in human c-myc that are involved in transformation and nuclear localization
-
Stone J, de Lange T, Ramsay G, et al. Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol 1987; 7: 1697-709.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 1697-1709
-
-
Stone, J.1
de Lange, T.2
Ramsay, G.3
-
28
-
-
0023136649
-
Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity
-
Sarid J, Halazonetis TD, Murphy W, Leder P. Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity. Proc Natl Acad Sci USA 1987; 84: 170-3.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 170-173
-
-
Sarid, J.1
Halazonetis, T.D.2
Murphy, W.3
Leder, P.4
-
29
-
-
0025461390
-
Definition of the activities and properties of c-myc required to inhibit cell differentiation
-
Freytag SO, Dang CV, Lee WM. Definition of the activities and properties of c-myc required to inhibit cell differentiation. Cell Growth Differ 1990; 1: 339-43.
-
(1990)
Cell Growth Differ
, vol.1
, pp. 339-343
-
-
Freytag, S.O.1
Dang, C.V.2
Lee, W.M.3
-
30
-
-
0028232627
-
Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts
-
Goruppi S, Gustincich S, Brancolini C, Lee WM, Schneider C. Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts. Oncogene 1994; 9: 1537-44.
-
(1994)
Oncogene
, vol.9
, pp. 1537-1544
-
-
Goruppi, S.1
Gustincich, S.2
Brancolini, C.3
Lee, W.M.4
Schneider, C.5
-
31
-
-
18644371442
-
Negative regulation of the mammalian UV response by Myc through association with Miz-1
-
Herold S, Wanzel M, Beuger V, et al. Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell 2002; 10: 509-21.
-
(2002)
Mol Cell
, vol.10
, pp. 509-521
-
-
Herold, S.1
Wanzel, M.2
Beuger, V.3
-
32
-
-
0037126303
-
Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
Seoane J, Le HV, Massague J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002; 419: 729-34.
-
(2002)
Nature
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massague, J.3
-
33
-
-
18644373146
-
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering M, Sancho E, Verweij C, et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002; 111: 241-50.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
van de Wetering, M.1
Sancho, E.2
Verweij, C.3
-
34
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005; 6: 635-45.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
35
-
-
82555169647
-
The role of the transcription factor Miz-1 in lymphocyte development and lymphomagenesis-Binding Myc makes the difference
-
Moroy T, Saba I, Kosan C. The role of the transcription factor Miz-1 in lymphocyte development and lymphomagenesis-Binding Myc makes the difference. Semin Immunol 2011; 23: 379-87.
-
(2011)
Semin Immunol
, vol.23
, pp. 379-387
-
-
Moroy, T.1
Saba, I.2
Kosan, C.3
-
36
-
-
0038185378
-
Genomic targets of the human c-Myc protein
-
Fernandez PC, Frank SR, Wang L, et al. Genomic targets of the human c-Myc protein. Genes Dev 2003; 17: 1115-29.
-
(2003)
Genes Dev
, vol.17
, pp. 1115-1129
-
-
Fernandez, P.C.1
Frank, S.R.2
Wang, L.3
-
37
-
-
0038492517
-
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells
-
Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci USA 2003; 100: 8164-9.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8164-8169
-
-
Li, Z.1
Van Calcar, S.2
Qu, C.3
Cavenee, W.K.4
Zhang, M.Q.5
Ren, B.6
-
38
-
-
0033676967
-
Bax is a transcriptional target and mediator of c-myc-induced apoptosis
-
Mitchell KO, Ricci MS, Miyashita T, et al. Bax is a transcriptional target and mediator of c-myc-induced apoptosis. Cancer Res 2000; 60: 6318-25.
-
(2000)
Cancer Res
, vol.60
, pp. 6318-6325
-
-
Mitchell, K.O.1
Ricci, M.S.2
Miyashita, T.3
-
39
-
-
0037144437
-
A novel myc target gene, mina53, that is involved in cell proliferation
-
Tsuneoka M, Koda Y, Soejima M, Teye K, Kimura H. A novel myc target gene, mina53, that is involved in cell proliferation. J Biol Chem 2002; 277: 35450-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 35450-35459
-
-
Tsuneoka, M.1
Koda, Y.2
Soejima, M.3
Teye, K.4
Kimura, H.5
-
40
-
-
0028336733
-
An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc
-
Gaubatz S, Meichle A, Eilers M. An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc. Mol Cell Biol 1994; 14: 3853-62.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3853-3862
-
-
Gaubatz, S.1
Meichle, A.2
Eilers, M.3
-
41
-
-
0026099022
-
The MYC protein activates transcription of the alpha-prothymosin gene
-
Eilers M, Schirm S, Bishop JM. The MYC protein activates transcription of the alpha-prothymosin gene. EMBO J 1991; 10: 133-41.
-
(1991)
EMBO J
, vol.10
, pp. 133-141
-
-
Eilers, M.1
Schirm, S.2
Bishop, J.M.3
-
42
-
-
0028930840
-
An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants
-
Miltenberger RJ, Sukow KA, Farnham PJ. An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants. Mol Cell Biol 1995; 15: 2527-35.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2527-2535
-
-
Miltenberger, R.J.1
Sukow, K.A.2
Farnham, P.J.3
-
43
-
-
0030921103
-
c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth
-
Shim H, Dolde C, Lewis BC, et al. c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc Natl Acad Sci USA 1997; 94: 6658-63.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
-
45
-
-
0030747725
-
Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals
-
Sears R, Ohtani K, Nevins JR. Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Mol Cell Biol 1997; 17: 5227-35.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5227-5235
-
-
Sears, R.1
Ohtani, K.2
Nevins, J.R.3
-
46
-
-
0028169192
-
c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II
-
Li LH, Nerlov C, Prendergast G, MacGregor D, Ziff EB. c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J 1994; 13: 4070-9.
-
(1994)
EMBO J
, vol.13
, pp. 4070-4079
-
-
Li, L.H.1
Nerlov, C.2
Prendergast, G.3
McGregor, D.4
Ziff, E.B.5
-
47
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
48
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008; 40: 43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
-
49
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005; 435: 839-43.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
51
-
-
79961173138
-
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
-
Steelman LS, Chappell WH, Abrams SL, et al. Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging. Aging (Albany NY) 2011; 3: 192-222.
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 192-222
-
-
Steelman, L.S.1
Chappell, W.H.2
Abrams, S.L.3
-
52
-
-
0034306997
-
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
-
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 2000; 14: 2501-14.
-
(2000)
Genes Dev
, vol.14
, pp. 2501-2514
-
-
Sears, R.1
Nuckolls, F.2
Haura, E.3
Taya, Y.4
Tamai, K.5
Nevins, J.R.6
-
53
-
-
0037541152
-
The MYC oncogene as a cancer drug target
-
Hermeking H. The MYC oncogene as a cancer drug target. Curr Cancer Drug Targets 2003; 3: 163-75.
-
(2003)
Curr Cancer Drug Targets
, vol.3
, pp. 163-175
-
-
Hermeking, H.1
-
54
-
-
0000538165
-
Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells
-
Dalla-Favera R, Bregni M, Erikson J, Patterson D, Gallo RC, Croce CM. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc Natl Acad Sci USA 1982; 79: 7824-7.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 7824-7827
-
-
Dalla-Favera, R.1
Bregni, M.2
Erikson, J.3
Patterson, D.4
Gallo, R.C.5
Croce, C.M.6
-
55
-
-
0035839844
-
Translocations involving c-myc and c-myc function
-
Boxer LM, Dang CV. Translocations involving c-myc and c-myc function. Oncogene 2001; 20: 5595-610.
-
(2001)
Oncogene
, vol.20
, pp. 5595-5610
-
-
Boxer, L.M.1
Dang, C.V.2
-
56
-
-
0033928972
-
The biology of multiple myeloma
-
Drach J, Kaufmann H, Urbauer E, Schreiber S, Ackermann J, Huber H. The biology of multiple myeloma. J Cancer Res Clin Oncol 2000; 126: 441-7.
-
(2000)
J Cancer Res Clin Oncol
, vol.126
, pp. 441-447
-
-
Drach, J.1
Kaufmann, H.2
Urbauer, E.3
Schreiber, S.4
Ackermann, J.5
Huber, H.6
-
57
-
-
0034602691
-
Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma
-
Shou Y, Martelli ML, Gabrea A, et al. Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma. Proc Natl Acad Sci USA 2000; 97: 228-33.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 228-233
-
-
Shou, Y.1
Martelli, M.L.2
Gabrea, A.3
-
58
-
-
1542377669
-
Comparative immunohistochemical analysis of pediatric Burkitt lymphoma and diffuse large B-cell lymphoma
-
Frost M, Newell J, Lones MA, Tripp SR, Cairo MS, Perkins SL. Comparative immunohistochemical analysis of pediatric Burkitt lymphoma and diffuse large B-cell lymphoma. Am J Clin Pathol 2004; 121: 384-92.
-
(2004)
Am J Clin Pathol
, vol.121
, pp. 384-392
-
-
Frost, M.1
Newell, J.2
Lones, M.A.3
Tripp, S.R.4
Cairo, M.S.5
Perkins, S.L.6
-
59
-
-
0026147847
-
MYC protein and proteins antigenically related with MYC in acute lymphoblastic leukemia
-
Miranda Peralta EI, Valles Ayoub Y, Hernandez Mendoza L, et al. [MYC protein and proteins antigenically related with MYC in acute lymphoblastic leukemia]. Rev Invest Clin 1991; 43: 139-45.
-
(1991)
Rev Invest Clin
, vol.43
, pp. 139-145
-
-
Miranda Peralta, E.I.1
Valles Ayoub, Y.2
Hernandez Mendoza, L.3
-
60
-
-
0035134989
-
Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases
-
Kraehn GM, Utikal J, Udart M, et al. Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases. Br J Cancer 2001; 84: 72-9.
-
(2001)
Br J Cancer
, vol.84
, pp. 72-79
-
-
Kraehn, G.M.1
Utikal, J.2
Udart, M.3
-
61
-
-
3042789990
-
Extra copies of c-myc are more pronounced in nodular melanomas than in superficial spreading melanomas as revealed by fluorescence in situ hybridisation
-
Treszl A, Adany R, Rakosy Z, et al. Extra copies of c-myc are more pronounced in nodular melanomas than in superficial spreading melanomas as revealed by fluorescence in situ hybridisation. Cytometry B Clin Cytom 2004; 60: 37-46.
-
(2004)
Cytometry B Clin Cytom
, vol.60
, pp. 37-46
-
-
Treszl, A.1
Adany, R.2
Rakosy, Z.3
-
62
-
-
0031800385
-
Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer
-
Masramon L, Arribas R, Tortola S, Perucho M, Peinado MA. Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer. Br J Cancer 1998; 77: 2349-56.
-
(1998)
Br J Cancer
, vol.77
, pp. 2349-2356
-
-
Masramon, L.1
Arribas, R.2
Tortola, S.3
Perucho, M.4
Peinado, M.A.5
-
63
-
-
70349317146
-
Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer
-
Camps J, Nguyen QT, Padilla-Nash HM, et al. Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. Genes Chromosomes Cancer 2009; 48: 1002-17.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 1002-1017
-
-
Camps, J.1
Nguyen, Q.T.2
Padilla-Nash, H.M.3
-
64
-
-
0026505212
-
C-myc amplification is a better prognostic factor than HER2/neu amplification in primary breast cancer
-
Berns EM, Klijn JG, van Putten WL, van Staveren IL, Portengen H, Foekens JA. c-myc amplification is a better prognostic factor than HER2/neu amplification in primary breast cancer. Cancer Res 1992; 52: 1107-13.
-
(1992)
Cancer Res
, vol.52
, pp. 1107-1113
-
-
Berns, E.M.1
Klijn, J.G.2
van Putten, W.L.3
van Staveren, I.L.4
Portengen, H.5
Foekens, J.A.6
-
65
-
-
0027263201
-
Amplification of c-myc but not of c-erbB-2 is associated with high proliferative capacity in breast cancer
-
Kreipe H, Feist H, Fischer L, et al. Amplification of c-myc but not of c-erbB-2 is associated with high proliferative capacity in breast cancer. Cancer Res 1993; 53: 1956-61.
-
(1993)
Cancer Res
, vol.53
, pp. 1956-1961
-
-
Kreipe, H.1
Feist, H.2
Fischer, L.3
-
66
-
-
0021053735
-
Amplification and expression of the c-myc oncogene in human lung cancer cell lines
-
Little CD, Nau MM, Carney DN, Gazdar AF, Minna JD. Amplification and expression of the c-myc oncogene in human lung cancer cell lines. Nature 1983; 306: 194-6.
-
(1983)
Nature
, vol.306
, pp. 194-196
-
-
Little, C.D.1
Nau, M.M.2
Carney, D.N.3
Gazdar, A.F.4
Minna, J.D.5
-
67
-
-
0021799560
-
Amplification of the c-myc oncogene in a subpopulation of human small cell lung cancer
-
Saksela K, Bergh J, Lehto VP, Nilsson K, Alitalo K. Amplification of the c-myc oncogene in a subpopulation of human small cell lung cancer. Cancer Res 1985; 45: 1823-7.
-
(1985)
Cancer Res
, vol.45
, pp. 1823-1827
-
-
Saksela, K.1
Bergh, J.2
Lehto, V.P.3
Nilsson, K.4
Alitalo, K.5
-
68
-
-
0025188561
-
C-myc amplification in ovarian cancer
-
Baker VV, Borst MP, Dixon D, Hatch KD, Shingleton HM, Miller D. c-myc amplification in ovarian cancer. Gynecol Oncol 1990; 38: 340-2.
-
(1990)
Gynecol Oncol
, vol.38
, pp. 340-342
-
-
Baker, V.V.1
Borst, M.P.2
Dixon, D.3
Hatch, K.D.4
Shingleton, H.M.5
Miller, D.6
-
69
-
-
33745239261
-
Fluorescence in situ hybridization analysis of c-myc amplification in stage TNM prostate cancer in Japanese patients
-
Sato H, Minei S, Hachiya T, Yoshida T and Takimoto Y. Fluorescence in situ hybridization analysis of c-myc amplification in stage TNM prostate cancer in Japanese patients. Int J Urol 2006; 13: 761-6.
-
(2006)
Int J Urol
, vol.13
, pp. 761-766
-
-
Sato, H.1
Minei, S.2
Hachiya, T.3
Yoshida, T.4
Takimoto, Y.5
-
70
-
-
84874319924
-
miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells
-
Abe W, Nasu K, Nakada C, Kawano Y, Moriyama M, Narahara H. miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells. Hum Reprod 2013; 28: 750-61.
-
(2013)
Hum Reprod
, vol.28
, pp. 750-761
-
-
Abe, W.1
Nasu, K.2
Nakada, C.3
Kawano, Y.4
Moriyama, M.5
Narahara, H.6
-
71
-
-
0021088187
-
Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma
-
Rabbitts TH, Hamlyn PH, Baer R. Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma. Nature 1983; 306: 760-5.
-
(1983)
Nature
, vol.306
, pp. 760-765
-
-
Rabbitts, T.H.1
Hamlyn, P.H.2
Baer, R.3
-
72
-
-
0026996760
-
C-myc hypermutation in Burkitt's lymphoma
-
Johnston JM, Carroll WL. c-myc hypermutation in Burkitt's lymphoma. Leuk Lymphoma 1992; 8: 431-9.
-
(1992)
Leuk Lymphoma
, vol.8
, pp. 431-439
-
-
Johnston, J.M.1
Carroll, W.L.2
-
73
-
-
0028055178
-
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines
-
Albert T, Urlbauer B, Kohlhuber F, Hammersen B, Eick D. Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines. Oncogene 1994; 9: 759-63.
-
(1994)
Oncogene
, vol.9
, pp. 759-763
-
-
Albert, T.1
Urlbauer, B.2
Kohlhuber, F.3
Hammersen, B.4
Eick, D.5
-
74
-
-
0028023421
-
Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
-
Lutterbach B, Hann SR. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol Cell Biol 1994; 14: 5510-22.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5510-5522
-
-
Lutterbach, B.1
Hann, S.R.2
-
75
-
-
79551552058
-
Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland
-
Wang X, Cunningham M, Zhang X, et al. Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland. Cancer Res 2011; 71: 925-36.
-
(2011)
Cancer Res
, vol.71
, pp. 925-936
-
-
Wang, X.1
Cunningham, M.2
Zhang, X.3
-
76
-
-
0034653998
-
C-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
Bahram F, von der Lehr N, Cetinkaya C, Larsson LG. c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood 2000; 95: 2104-10.
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.1
von der Lehr, N.2
Cetinkaya, C.3
Larsson, L.G.4
-
77
-
-
84863115732
-
Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression
-
Zhang X, Farrell AS, Daniel CJ, et al. Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression. Proc Natl Acad Sci USA 2012; 109: 2790-5.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2790-2795
-
-
Zhang, X.1
Farrell, A.S.2
Daniel, C.J.3
-
78
-
-
0035118130
-
A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation
-
Bazarov AV, Adachi S, Li SF, Mateyak MK, Wei S, Sedivy JM. A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation. Cancer Res 2001; 61: 1178-86.
-
(2001)
Cancer Res
, vol.61
, pp. 1178-1186
-
-
Bazarov, A.V.1
Adachi, S.2
Li, S.F.3
Mateyak, M.K.4
Wei, S.5
Sedivy, J.M.6
-
80
-
-
0028998491
-
Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter
-
Kim HG, Miller DM. Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter. Biochemistry 1995; 34: 8165-71.
-
(1995)
Biochemistry
, vol.34
, pp. 8165-8171
-
-
Kim, H.G.1
Miller, D.M.2
-
81
-
-
0034660876
-
Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells
-
McGuffie EM, Pacheco D, Carbone GM, Catapano CV. Antigene and antiproliferative effects of a c-myc-targeting phosphorothioate triple helix-forming oligonucleotide in human leukemia cells. Cancer Res 2000; 60: 3790-9.
-
(2000)
Cancer Res
, vol.60
, pp. 3790-3799
-
-
McGuffie, E.M.1
Pacheco, D.2
Carbone, G.M.3
Catapano, C.V.4
-
82
-
-
0037096781
-
Design of a novel triple helix-forming oligodeoxyribonucleotide directed to the major promoter of the c-myc gene
-
McGuffie EM, Catapano CV. Design of a novel triple helix-forming oligodeoxyribonucleotide directed to the major promoter of the c-myc gene. Nucleic Acids Res 2002; 30: 2701-9.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2701-2709
-
-
McGuffie, E.M.1
Catapano, C.V.2
-
83
-
-
32644432553
-
Growth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming oligonucleotides targeting the c-myc gene in prostate cancer cells
-
Napoli S, Negri U, Arcamone F, Capobianco ML, Carbone GM, Catapano CV. Growth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming oligonucleotides targeting the c-myc gene in prostate cancer cells. Nucleic Acids Res 2006; 34: 734-44.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 734-744
-
-
Napoli, S.1
Negri, U.2
Arcamone, F.3
Capobianco, M.L.4
Carbone, G.M.5
Catapano, C.V.6
-
84
-
-
2342461708
-
DNA binding and antigene activity of a daunomycin-conjugated triplex-forming oligonucleotide targeting the P2 promoter of the human c-myc gene
-
Carbone GM, McGuffie E, Napoli S, et al. DNA binding and antigene activity of a daunomycin-conjugated triplex-forming oligonucleotide targeting the P2 promoter of the human c-myc gene. Nucleic Acids Res 2004; 32: 2396-410.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 2396-2410
-
-
Carbone, G.M.1
McGuffie, E.2
Napoli, S.3
-
85
-
-
0036597090
-
The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo
-
Grand CL, Han H, Munoz RM, et al. The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo. Mol Cancer Ther 2002; 1: 565-73.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 565-573
-
-
Grand, C.L.1
Han, H.2
Munoz, R.M.3
-
86
-
-
77957044322
-
Selective targeting of G-quadruplex using furan-based cyclic homooligopeptides: Effect on c-MYC expression
-
Agarwal T, Roy S, Chakraborty TK, Maiti S. Selective targeting of G-quadruplex using furan-based cyclic homooligopeptides: effect on c-MYC expression. Biochemistry 2010; 49: 8388-97.
-
(2010)
Biochemistry
, vol.49
, pp. 8388-8397
-
-
Agarwal, T.1
Roy, S.2
Chakraborty, T.K.3
Maiti, S.4
-
87
-
-
34147100699
-
Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives
-
Ou TM, Lu YJ, Zhang C, et al. Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives. J Med Chem 2007; 50: 1465-74.
-
(2007)
J Med Chem
, vol.50
, pp. 1465-1474
-
-
Ou, T.M.1
Lu, Y.J.2
Zhang, C.3
-
88
-
-
84861625962
-
12-N-Methylated 5, 6-dihydrobenzo[c]acridine derivatives: A new class of highly selective ligands for c-myc G-quadruplex DNA
-
Liao SR, Zhou CX, Wu WB, et al. 12-N-Methylated 5, 6-dihydrobenzo[c]acridine derivatives: a new class of highly selective ligands for c-myc G-quadruplex DNA. Eur J Med Chem 2012; 53: 52-63.
-
(2012)
Eur J Med Chem
, vol.53
, pp. 52-63
-
-
Liao, S.R.1
Zhou, C.X.2
Wu, W.B.3
-
89
-
-
84877812258
-
FDA-approved drugs selected using virtual screening bind specifically to G-quadruplex DNA
-
Castillo-Gonzalez D, Perez-Machado G, Guedin A, Mergny JL, Cabrera-Perez MA. FDA-approved drugs selected using virtual screening bind specifically to G-quadruplex DNA. Curr Pharm Des 2013; 19: 2164-73.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 2164-2173
-
-
Castillo-Gonzalez, D.1
Perez-Machado, G.2
Guedin, A.3
Mergny, J.L.4
Cabrera-Perez, M.A.5
-
90
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
Delmore JE, Issa GC, Lemieux ME, et al. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 2011; 146: 904-17.
-
(2011)
Cell
, vol.146
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
-
91
-
-
0023227831
-
A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1
-
Heikkila R, Schwab G, Wickstrom E, et al. A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1. Nature 1987; 328: 445-9.
-
(1987)
Nature
, vol.328
, pp. 445-449
-
-
Heikkila, R.1
Schwab, G.2
Wickstrom, E.3
-
92
-
-
0023954113
-
An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation
-
Holt JT, Redner RL, Nienhuis AW. An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation. Mol Cell Biol 1988; 8: 963-73.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 963-973
-
-
Holt, J.T.1
Redner, R.L.2
Nienhuis, A.W.3
-
93
-
-
0023786827
-
C-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells
-
Prochownik EV, Kukowska J, Rodgers C. c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells. Mol Cell Biol 1988; 8: 3683-95.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 3683-3695
-
-
Prochownik, E.V.1
Kukowska, J.2
Rodgers, C.3
-
94
-
-
0023927355
-
Specific inhibition of c-myc protein biosynthesis using an antisense synthetic deoxy-oligonucleotide in human T lymphocytes
-
Harel-Bellan A, Ferris DK, Vinocour M, Holt JT, Farrar WL. Specific inhibition of c-myc protein biosynthesis using an antisense synthetic deoxy-oligonucleotide in human T lymphocytes. J Immunol 1988; 140: 2431-5.
-
(1988)
J Immunol
, vol.140
, pp. 2431-2435
-
-
Harel-Bellan, A.1
Ferris, D.K.2
Vinocour, M.3
Holt, J.T.4
Farrar, W.L.5
-
95
-
-
0028935119
-
Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells
-
Kimura S, Maekawa T, Hirakawa K, Murakami A, Abe T. Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells. Cancer Res 1995; 55: 1379-84.
-
(1995)
Cancer Res
, vol.55
, pp. 1379-1384
-
-
Kimura, S.1
Maekawa, T.2
Hirakawa, K.3
Murakami, A.4
Abe, T.5
-
96
-
-
0029360643
-
Prevention of tumor formation in a mouse model of Burkitt's lymphoma by 6 weeks of treatment with anti-c-myc DNA phosphorothioate
-
Huang Y, Snyder R, Kligshteyn M, Wickstrom E. Prevention of tumor formation in a mouse model of Burkitt's lymphoma by 6 weeks of treatment with anti-c-myc DNA phosphorothioate. Mol Med 1995; 1: 647-58.
-
(1995)
Mol Med
, vol.1
, pp. 647-658
-
-
Huang, Y.1
Snyder, R.2
Kligshteyn, M.3
Wickstrom, E.4
-
97
-
-
0032486759
-
Antisense c-myc and immunostimulatory oligonucleotide inhibition of tumorigenesis in a murine B-cell lymphoma transplant model
-
Smith JB, Wickstrom E. Antisense c-myc and immunostimulatory oligonucleotide inhibition of tumorigenesis in a murine B-cell lymphoma transplant model. J Natl Cancer Inst 1998; 90: 1146-54.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1146-1154
-
-
Smith, J.B.1
Wickstrom, E.2
-
98
-
-
0036606633
-
Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: Implications for the antiproliferative effects of antiestrogens
-
Carroll JS, Swarbrick A, Musgrove EA, Sutherland RL. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. Cancer Res 2002; 62: 3126-31.
-
(2002)
Cancer Res
, vol.62
, pp. 3126-3131
-
-
Carroll, J.S.1
Swarbrick, A.2
Musgrove, E.A.3
Sutherland, R.L.4
-
99
-
-
0034881060
-
Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line
-
Leonetti C, Biroccio A, Benassi B, et al. Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line. Cancer Gene Ther 2001; 8: 459-68.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 459-468
-
-
Leonetti, C.1
Biroccio, A.2
Benassi, B.3
-
100
-
-
0035216893
-
Cationic liposomes enhance cellular/nuclear localization of 99mTc-antisense oligonucleotides in target tumor cells
-
Zhang YM, Rusckowski M, Liu N, Liu C, Hnatowich DJ. Cationic liposomes enhance cellular/nuclear localization of 99mTc-antisense oligonucleotides in target tumor cells. Cancer Biother Radiopharm 2001; 16: 411-9.
-
(2001)
Cancer Biother Radiopharm
, vol.16
, pp. 411-419
-
-
Zhang, Y.M.1
Rusckowski, M.2
Liu, N.3
Liu, C.4
Hnatowich, D.J.5
-
101
-
-
0034656564
-
Antisense delivery using protamine-oligonucleotide particles
-
Junghans M, Kreuter J, Zimmer A. Antisense delivery using protamine-oligonucleotide particles. Nucleic Acids Res 2000; 28: E45.
-
(2000)
Nucleic Acids Res
, vol.28
-
-
Junghans, M.1
Kreuter, J.2
Zimmer, A.3
-
102
-
-
0034655249
-
Dihydrotestosterone as a selective cellular/nuclear localization vector for anti-gene peptide nucleic acid in prostatic carcinoma cells
-
Boffa LC, Scarfi S, Mariani MR, et al. Dihydrotestosterone as a selective cellular/nuclear localization vector for anti-gene peptide nucleic acid in prostatic carcinoma cells. Cancer Res 2000; 60: 2258-62.
-
(2000)
Cancer Res
, vol.60
, pp. 2258-2262
-
-
Boffa, L.C.1
Scarfi, S.2
Mariani, M.R.3
-
104
-
-
0032990450
-
Oligonucleotide therapeutics: Clothing the emperor
-
Gewirtz AM. Oligonucleotide therapeutics: clothing the emperor. Curr Opin Mol Ther 1999; 1: 297-306.
-
(1999)
Curr Opin Mol Ther
, vol.1
, pp. 297-306
-
-
Gewirtz, A.M.1
-
105
-
-
0034093722
-
Antisense therapeutics in chronic myeloid leukaemia: The promise, the progress and the problems
-
Clark RE. Antisense therapeutics in chronic myeloid leukaemia: the promise, the progress and the problems. Leukemia 2000; 14: 347-55.
-
(2000)
Leukemia
, vol.14
, pp. 347-355
-
-
Clark, R.E.1
-
106
-
-
0035140240
-
Molecular therapy with recombinant antisense c-myc adenovirus for human gastric carcinoma cells in vitro and in vivo
-
Chen JP, Lin C, Xu CP, et al. Molecular therapy with recombinant antisense c-myc adenovirus for human gastric carcinoma cells in vitro and in vivo. J Gastroenterol Hepatol 2001; 16: 22-8.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, pp. 22-28
-
-
Chen, J.P.1
Lin, C.2
Xu, C.P.3
-
107
-
-
0035017537
-
Reduction of c-myc expression by an antisense approach under Cre/loxP switching induces apoptosis in human liver cancer cells
-
Ebinuma H, Saito H, Kosuga M, et al. Reduction of c-myc expression by an antisense approach under Cre/loxP switching induces apoptosis in human liver cancer cells. J Cell Physiol 2001; 188: 56-66.
-
(2001)
J Cell Physiol
, vol.188
, pp. 56-66
-
-
Ebinuma, H.1
Saito, H.2
Kosuga, M.3
-
108
-
-
23844448634
-
Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo
-
Wang YH, Liu S, Zhang G, et al. Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo. Breast Cancer Res 2005; 7: R220-8.
-
(2005)
Breast Cancer Res
, vol.7
, pp. R220-R228
-
-
Wang, Y.H.1
Liu, S.2
Zhang, G.3
-
109
-
-
78449286445
-
Tumor cell kill by c-MYC depletion: Role of MYC-regulated genes that control DNA double-strand break repair
-
Luoto KR, Meng AX, Wasylishen AR, et al. Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair. Cancer Res 2010; 70: 8748-59.
-
(2010)
Cancer Res
, vol.70
, pp. 8748-8759
-
-
Luoto, K.R.1
Meng, A.X.2
Wasylishen, A.R.3
-
110
-
-
15744373826
-
Silencing of human c-myc oncogene expression by poly-DNP-RNA
-
Shen L, Zhang C, Ambrus JL, Wang JH. Silencing of human c-myc oncogene expression by poly-DNP-RNA. Oligonucleotides 2005; 15: 23-35.
-
(2005)
Oligonucleotides
, vol.15
, pp. 23-35
-
-
Shen, L.1
Zhang, C.2
Ambrus, J.L.3
Wang, J.H.4
-
111
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
Sampson VB, Rong NH, Han J, et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007; 67: 9762-70.
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
-
112
-
-
77953232823
-
The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice
-
He XY, Chen JX, Zhang Z, Li CL, Peng QL, Peng HM. The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice. J Cancer Res Clin Oncol 2010; 136: 1023-8.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 1023-1028
-
-
He, X.Y.1
Chen, J.X.2
Zhang, Z.3
Li, C.L.4
Peng, Q.L.5
Peng, H.M.6
-
113
-
-
78649561463
-
Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A)
-
Lan FF, Wang H, Chen YC, et al. Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A). Int J Cancer 2011; 128: 319-31.
-
(2011)
Int J Cancer
, vol.128
, pp. 319-331
-
-
Lan, F.F.1
Wang, H.2
Chen, Y.C.3
-
114
-
-
84862908609
-
MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells
-
Nadiminty N, Tummala R, Lou W, et al. MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. J Biol Chem 2012; 287: 1527-37.
-
(2012)
J Biol Chem
, vol.287
, pp. 1527-1537
-
-
Nadiminty, N.1
Tummala, R.2
Lou, W.3
-
115
-
-
79954431152
-
MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression
-
Wong TS, Man OY, Tsang CM, et al. MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression. J Cancer Res Clin Oncol 2011; 137: 415-22.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 415-422
-
-
Wong, T.S.1
Man, O.Y.2
Tsang, C.M.3
-
116
-
-
62549148270
-
p53 represses c-Myc through induction of the tumor suppressor miR-145
-
Sachdeva M, Zhu S, Wu F, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106: 3207-12.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3207-3212
-
-
Sachdeva, M.1
Zhu, S.2
Wu, F.3
-
117
-
-
78549269168
-
miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc
-
Chen Z, Zeng H, Guo Y, et al. miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. J Exp Clin Cancer Res 2010; 29: 151.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 151
-
-
Chen, Z.1
Zeng, H.2
Guo, Y.3
-
118
-
-
69949098536
-
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements
-
Lal A, Navarro F, Maher CA, et al. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell 2009; 35: 610-25.
-
(2009)
Mol Cell
, vol.35
, pp. 610-625
-
-
Lal, A.1
Navarro, F.2
Maher, C.A.3
-
119
-
-
84874502379
-
Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma
-
Yamada Y, Hidaka H, Seki N, et al. Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma. Cancer Sci 2013; 104: 304-12.
-
(2013)
Cancer Sci
, vol.104
, pp. 304-312
-
-
Yamada, Y.1
Hidaka, H.2
Seki, N.3
-
120
-
-
84878682019
-
Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions
-
Jung HM, Patel RS, Phillips BL, et al. Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions. Mol Biol Cell 2013; 24: 1638-48, S1-7.
-
(2013)
Mol Biol Cell
, vol.24
-
-
Jung, H.M.1
Patel, R.S.2
Phillips, B.L.3
-
121
-
-
84876493330
-
MiR-449c targets c-Myc and inhibits NSCLC cell progression
-
Miao LJ, Huang SF, Sun ZT, et al. MiR-449c targets c-Myc and inhibits NSCLC cell progression. FEBS Lett 2013; 587: 1359-65.
-
(2013)
FEBS Lett
, vol.587
, pp. 1359-1365
-
-
Miao, L.J.1
Huang, S.F.2
Sun, Z.T.3
-
122
-
-
63649086487
-
Targeting the ubiquitin system in cancer therapy
-
Hoeller D, Dikic I. Targeting the ubiquitin system in cancer therapy. Nature 2009; 458: 438-44.
-
(2009)
Nature
, vol.458
, pp. 438-444
-
-
Hoeller, D.1
Dikic, I.2
-
123
-
-
2942614705
-
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
-
Yada M, Hatakeyama S, Kamura T, et al. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J 2004; 23: 2116-25.
-
(2004)
EMBO J
, vol.23
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
-
124
-
-
12444264823
-
The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription
-
von der Lehr N, Johansson S, Wu S, et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol Cell 2003; 11: 1189-200.
-
(2003)
Mol Cell
, vol.11
, pp. 1189-1200
-
-
von der Lehr, N.1
Johansson, S.2
Wu, S.3
-
125
-
-
0037648338
-
Skp2 regulates Myc protein stability and activity
-
Kim SY, Herbst A, Tworkowski KA, Salghetti SE, Tansey WP. Skp2 regulates Myc protein stability and activity. Mol Cell 2003; 11: 1177-88.
-
(2003)
Mol Cell
, vol.11
, pp. 1177-1188
-
-
Kim, S.Y.1
Herbst, A.2
Tworkowski, K.A.3
Salghetti, S.E.4
Tansey, W.P.5
-
126
-
-
84874785567
-
The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity
-
Paul I, Ahmed SF, Bhowmik A, Deb S, Ghosh MK. The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity. Oncogene 2013; 32: 1284-95.
-
(2013)
Oncogene
, vol.32
, pp. 1284-1295
-
-
Paul, I.1
Ahmed, S.F.2
Bhowmik, A.3
Deb, S.4
Ghosh, M.K.5
-
127
-
-
32944455992
-
The immunomodulatory benzodiazepine Bz-423 inhibits B-cell proliferation by targeting c-myc protein for rapid and specific degradation
-
Sundberg TB, Ney GM, Subramanian C, Opipari AW, Jr., Glick GD. The immunomodulatory benzodiazepine Bz-423 inhibits B-cell proliferation by targeting c-myc protein for rapid and specific degradation. Cancer Res 2006; 66: 1775-82.
-
(2006)
Cancer Res
, vol.66
, pp. 1775-1782
-
-
Sundberg, T.B.1
Ney, G.M.2
Subramanian, C.3
Opipari, A.W.4
Glick, G.D.5
-
128
-
-
77949514451
-
Mechanisms of c-myc degradation by nickel compounds and hypoxia
-
Li Q, Kluz T, Sun H, Costa M. Mechanisms of c-myc degradation by nickel compounds and hypoxia. PLoS One 2009; 4: e8531.
-
(2009)
PLoS One
, vol.4
-
-
Li, Q.1
Kluz, T.2
Sun, H.3
Costa, M.4
-
129
-
-
24744441049
-
Targeted destruction of c-Myc by an engineered ubiquitin ligase suppresses cell transformation and tumor formation
-
Hatakeyama S, Watanabe M, Fujii Y, Nakayama KI. Targeted destruction of c-Myc by an engineered ubiquitin ligase suppresses cell transformation and tumor formation. Cancer Res 2005; 65: 7874-9.
-
(2005)
Cancer Res
, vol.65
, pp. 7874-7879
-
-
Hatakeyama, S.1
Watanabe, M.2
Fujii, Y.3
Nakayama, K.I.4
-
130
-
-
2542461324
-
A protein knockdown strategy to study the function of beta-catenin in tumorigenesis
-
Cong F, Zhang J, Pao W, Zhou P, Varmus H. A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. BMC Mol Biol 2003; 4: 10.
-
(2003)
BMC Mol Biol
, vol.4
, pp. 10
-
-
Cong, F.1
Zhang, J.2
Pao, W.3
Zhou, P.4
Varmus, H.5
-
131
-
-
0037133575
-
Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts
-
Berg T, Cohen SB, Desharnais J, et al. Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts. Proc Natl Acad Sci USA 2002; 99: 3830-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3830-3835
-
-
Berg, T.1
Cohen, S.B.2
Desharnais, J.3
-
132
-
-
0142057146
-
Low molecular weight inhibitors of Myc-Max interaction and function
-
Yin X, Giap C, Lazo JS, Prochownik EV. Low molecular weight inhibitors of Myc-Max interaction and function. Oncogene 2003; 22: 6151-9.
-
(2003)
Oncogene
, vol.22
, pp. 6151-6159
-
-
Yin, X.1
Giap, C.2
Lazo, J.S.3
Prochownik, E.V.4
-
133
-
-
34748867198
-
Improved low molecular weight Myc-Max inhibitors
-
Wang H, Hammoudeh DI, Follis AV, et al. Improved low molecular weight Myc-Max inhibitors. Mol Cancer Ther 2007; 6: 2399-408.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2399-2408
-
-
Wang, H.1
Hammoudeh, D.I.2
Follis, A.V.3
-
134
-
-
33646551232
-
Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation
-
Mo H, Henriksson M. Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation. Proc Natl Acad Sci USA 2006; 103: 6344-9.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6344-6349
-
-
Mo, H.1
Henriksson, M.2
-
135
-
-
33746961739
-
Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy
-
Weinstein IB, Joe AK. Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy. Nat Clin Pract Oncol 2006; 3: 448-57.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 448-457
-
-
Weinstein, I.B.1
Joe, A.K.2
-
136
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344: 783-92.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
137
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351: 337-45.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
138
-
-
78650625238
-
Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia
-
Preudhomme C, Guilhot J, Nicolini FE, et al. Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia. N Engl J Med 2010; 363: 2511-21.
-
(2010)
N Engl J Med
, vol.363
, pp. 2511-2521
-
-
Preudhomme, C.1
Guilhot, J.2
Nicolini, F.E.3
-
139
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
Vaux DL, Cory S, Adams JM. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335: 440-2.
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
140
-
-
79960631098
-
Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression
-
Sasaki N, Kuroda J, Nagoshi H, et al. Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression. Exp Hematol 2011; 39: 817-28 e1.
-
(2011)
Exp Hematol
, vol.39
-
-
Sasaki, N.1
Kuroda, J.2
Nagoshi, H.3
-
141
-
-
16344371749
-
Antitumor efficacy of bcl-2 and c-myc antisense oligonucleotides in combination with cisplatin in human melanoma xenografts: Relevance of the administration sequence
-
Zupi G, Scarsella M, Semple SC, Mottolese M, Natali PG, Leonetti C. Antitumor efficacy of bcl-2 and c-myc antisense oligonucleotides in combination with cisplatin in human melanoma xenografts: relevance of the administration sequence. Clin Cancer Res 2005; 11: 1990-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1990-1998
-
-
Zupi, G.1
Scarsella, M.2
Semple, S.C.3
Mottolese, M.4
Natali, P.G.5
Leonetti, C.6
-
142
-
-
34548736559
-
Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer
-
Leonetti C, Biroccio A, DAngelo C, Semple SC, Scarsella M, Zupi G. Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer. Prostate 2007; 67: 1475-85.
-
(2007)
Prostate
, vol.67
, pp. 1475-1485
-
-
Leonetti, C.1
Biroccio, A.2
Dangelo, C.3
Semple, S.C.4
Scarsella, M.5
Zupi, G.6
-
143
-
-
0036229111
-
Combination antigene therapy targeting c-myc and c-erbB(2) in the ovarian cancer COC(1) cell line
-
Fei R, Shaoyang L. Combination antigene therapy targeting c-myc and c-erbB(2) in the ovarian cancer COC(1) cell line. Gynecol Oncol 2002; 85: 40-4.
-
(2002)
Gynecol Oncol
, vol.85
, pp. 40-44
-
-
Fei, R.1
Shaoyang, L.2
-
144
-
-
1342308035
-
Specific inhibition of gene expression and transactivation functions of hepatitis B virus X protein and c-myc by small interfering RNAs
-
Hung L, Kumar V. Specific inhibition of gene expression and transactivation functions of hepatitis B virus X protein and c-myc by small interfering RNAs. FEBS Lett 2004; 560: 210-4.
-
(2004)
FEBS Lett
, vol.560
, pp. 210-214
-
-
Hung, L.1
Kumar, V.2
-
145
-
-
0031963158
-
C-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice
-
Citro G, D'Agnano I, Leonetti C, et al. c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice. Cancer Res 1998; 58: 283-9.
-
(1998)
Cancer Res
, vol.58
, pp. 283-289
-
-
Citro, G.1
D'Agnano, I.2
Leonetti, C.3
-
146
-
-
0032852873
-
Increase of cisplatin sensitivity by c-myc antisense oligodeoxynucleotides in a human metastatic melanoma inherently resistant to cisplatin
-
Leonetti C, Biroccio A, Candiloro A, et al. Increase of cisplatin sensitivity by c-myc antisense oligodeoxynucleotides in a human metastatic melanoma inherently resistant to cisplatin. Clin Cancer Res 1999; 5: 2588-95.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2588-2595
-
-
Leonetti, C.1
Biroccio, A.2
Candiloro, A.3
-
147
-
-
0036606156
-
Acridine-modified, clamp-forming antisense oligonucleotides synergize with cisplatin to inhibit c-Myc expression and B16-F0 tumor progression
-
Stewart DA, Xu X, Thomas SD, Miller DM. Acridine-modified, clamp-forming antisense oligonucleotides synergize with cisplatin to inhibit c-Myc expression and B16-F0 tumor progression. Nucleic Acids Res 2002; 30: 2565-74.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2565-2574
-
-
Stewart, D.A.1
Xu, X.2
Thomas, S.D.3
Miller, D.M.4
-
148
-
-
33845712932
-
Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells
-
Lin CP, Liu JD, Chow JM, Liu CR, Liu HE. Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. Anticancer Drugs 2007; 18: 161-70.
-
(2007)
Anticancer Drugs
, vol.18
, pp. 161-170
-
-
Lin, C.P.1
Liu, J.D.2
Chow, J.M.3
Liu, C.R.4
Liu, H.E.5
-
149
-
-
71249164186
-
Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines
-
Xie XK, Yang DS, Ye ZM, Tao HM. Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines. Chemotherapy 2009; 55: 433-40.
-
(2009)
Chemotherapy
, vol.55
, pp. 433-440
-
-
Xie, X.K.1
Yang, D.S.2
Ye, Z.M.3
Tao, H.M.4
-
150
-
-
29144445979
-
Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc
-
Bidwell GL, 3rd, Raucher D. Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc. Biochem Pharmacol 2006; 71: 248-56.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 248-256
-
-
Bidwell, G.L.1
Raucher, D.2
-
151
-
-
38549126565
-
Increase of therapeutic effects by treating melanoma with targeted combinations of c-myc antisense and doxorubicin
-
Pastorino F, Mumbengegwi DR, Ribatti D, Ponzoni M, Allen TM. Increase of therapeutic effects by treating melanoma with targeted combinations of c-myc antisense and doxorubicin. J Control Release 2008; 126: 85-94.
-
(2008)
J Control Release
, vol.126
, pp. 85-94
-
-
Pastorino, F.1
Mumbengegwi, D.R.2
Ribatti, D.3
Ponzoni, M.4
Allen, T.M.5
-
153
-
-
84906240020
-
Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer
-
Boulware SB, Christensen LA, Thames H, Coghlan L, Vasquez KM, Finch RA. Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer. Mol Carcinog 2013; DOI: 10. 1002/mc. 22026.
-
(2013)
Mol Carcinog
-
-
Boulware, S.B.1
Christensen, L.A.2
Thames, H.3
Coghlan, L.4
Vasquez, K.M.5
Finch, R.A.6
-
154
-
-
84881670536
-
Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy
-
Zhang Y, Peng L, Mumper RJ, Huang L. Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy. Biomaterials 2013; DOI; 10. 1016/j. biomaterials. 2013. 07. 050.
-
(2013)
Biomaterials
-
-
Zhang, Y.1
Peng, L.2
Mumper, R.J.3
Huang, L.4
-
155
-
-
84905995986
-
Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S
-
Weng HY, Huang HL, Dong BW, Zhao PP, Zhou H, Qu LH. Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S. Cancer Res 2014; DOI: 10. 1158/0008-5472. CAN-13-1748.
-
(2014)
Cancer Res
-
-
Weng, H.Y.1
Huang, H.L.2
Dong, B.W.3
Zhao, P.P.4
Zhou, H.5
Qu, L.H.6
-
156
-
-
0032905924
-
C-Myc target genes involved in cell growth, apoptosis, and metabolism
-
Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 1999; 19: 1-11.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1-11
-
-
Dang, C.V.1
-
157
-
-
2342495721
-
Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway
-
Wang Y, Engels IH, Knee DA, Nasoff M, Deveraux QL, Quon KC. Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway. Cancer Cell 2004; 5: 501-12.
-
(2004)
Cancer Cell
, vol.5
, pp. 501-512
-
-
Wang, Y.1
Engels, I.H.2
Knee, D.A.3
Nasoff, M.4
Deveraux, Q.L.5
Quon, K.C.6
-
158
-
-
84861735363
-
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
-
Horiuchi D, Kusdra L, Huskey NE, et al. MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J Exp Med 2012; 209: 679-96.
-
(2012)
J Exp Med
, vol.209
, pp. 679-696
-
-
Horiuchi, D.1
Kusdra, L.2
Huskey, N.E.3
-
159
-
-
77956369534
-
Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
-
Yang D, Liu H, Goga A, Kim S, Yuneva M, Bishop JM. Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase. Proc Natl Acad Sci USA 2010; 107: 13836-41.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13836-13841
-
-
Yang, D.1
Liu, H.2
Goga, A.3
Kim, S.4
Yuneva, M.5
Bishop, J.M.6
-
160
-
-
84861171712
-
Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis
-
Lin CJ, Nasr Z, Premsrirut PK, et al. Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis. Cell Rep 2012; 1: 325-33.
-
(2012)
Cell Rep
, vol.1
, pp. 325-333
-
-
Lin, C.J.1
Nasr, Z.2
Premsrirut, P.K.3
-
161
-
-
84856069665
-
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
-
Kessler JD, Kahle KT, Sun T, et al. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science 2012; 335: 348-53.
-
(2012)
Science
, vol.335
, pp. 348-353
-
-
Kessler, J.D.1
Kahle, K.T.2
Sun, T.3
|