Ligand binding reveals a role for heme in translationally-controlled tumor protein dimerization

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Lucas, Andrew T ^a   Fu, Xiangping ^a   Liu, JingJing ^a   Brannon, Mary K ^a   Yang, Jianhua ^a,b   Capelluto, Daniel G S ^a   Finkielstein, Carla V ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CALCIUM; HEME; HISTIDINE; OLIGOMER; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; CROSS LINKING REAGENT; HEMIN; PROTEIN BINDING; TUMOR MARKER; TUMOR PROTEIN, TRANSLATIONALLY-CONTROLLED 1;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE REGULATION; CELL DEATH; CELL GROWTH; CELL TRANSFORMATION; CONFORMATIONAL TRANSITION; DIMERIZATION; HOMEOSTASIS; HUMAN; LIGAND BINDING; MICROTUBULE; OLIGOMERIZATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; BIOLOGY; CHEMISTRY; CIRCULAR DICHROISM; FLUORESCENCE; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; ULTRACENTRIFUGATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BIOMARKERS, TUMOR; CALCIUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; COMPUTATIONAL BIOLOGY; CROSS-LINKING REAGENTS; DIMERIZATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENCE; HEMIN; HOMEOSTASIS; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; ULTRACENTRIFUGATION;

EID: 84911469156     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112823     Document Type: Article

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