Pluronic-poly (acrylic acid)-cysteine/Pluronic L121 mixed micelles improve the oral bioavailability of paclitaxel

Drug Development and Industrial Pharmacy

Volumn 40, Issue 11, 2014, Pages 1483-1493

  Zhao, Yanli ^a   Li, Yanli ^b   Ge, Jianjun ^a   Li, Na ^a   Li, Ling Bing ^a  

^a SHANDONG UNIVERSITY   (China)

^b Fourth People's Hospital of Jinan   (China)

Author keywords

Oral drug delivery; P glycoprotein; Paclitaxel; Pluronic poly(acrylic acid) cysteine; Thiomers

Indexed keywords

COPOLYMER; CYSTEINE; PACLITAXEL; PLURONIC POLY(ACRYLIC ACID) CYSTEINE; POLOXAMER; POLYACRYLIC ACID; THIOL GROUP; UNCLASSIFIED DRUG; ACRYLIC ACID RESIN; CARBOPOL 940; DRUG CARRIER; MICELLE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; DISULFIDE BOND; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG RELEASE; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MICELLE; NONHUMAN; PHYSICAL CHEMISTRY; PLASMA CONCENTRATION-TIME CURVE; RAT; SINGLE DRUG DOSE; SMALL INTESTINE ABSORPTION; SYNTHESIS; TAXUS WALLICHIANA VAR. CHINENSIS; ANIMAL; AREA UNDER THE CURVE; BIOAVAILABILITY; CHEMISTRY; INTESTINE ABSORPTION; MALE; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; WISTAR RAT;

ACRYLIC RESINS; ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CYSTEINE; DRUG CARRIERS; INTESTINAL ABSORPTION; MALE; MICELLES; PACLITAXEL; PARTICLE SIZE; POLOXAMER; RATS; RATS, WISTAR; VERAPAMIL;

EID: 84911463923     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.829487     Document Type: Article

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