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Volumn 289, Issue 46, 2014, Pages 32276-32290

MicroRNA-125a reduces proliferation and invasion of oral squamous cell carcinoma cells by targeting estrogenrelated receptor α: Implications for cancer therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELL PROLIFERATION; MAMMALS; TRANSCRIPTION; TUMORS;

EID: 84911409223     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.584136     Document Type: Article
Times cited : (54)

References (50)
  • 2
    • 0023857147 scopus 로고
    • Identification of a new class of steroid hormone receptors
    • Giguère, V., Yang, N., Segui, P., and Evans, R. M. (1988) Identification of a new class of steroid hormone receptors. Nature 331, 91-94
    • (1988) Nature , vol.331 , pp. 91-94
    • Giguère, V.1    Yang, N.2    Segui, P.3    Evans, R.M.4
  • 3
    • 0030787844 scopus 로고    scopus 로고
    • The orphan nuclear receptor estrogen-related receptorα is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene
    • Sladek, R., Bader, J. A., and Giguère, V. (1997) The orphan nuclear receptor estrogen-related receptorα is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol. Cell. Biol. 17, 5400-5409
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5400-5409
    • Sladek, R.1    Bader, J.A.2    Giguère, V.3
  • 4
    • 0037112441 scopus 로고    scopus 로고
    • Estrogen-related receptor α and estrogen-related receptor γ associate with unfavorable and favorable biomarkers, respectively, in human breast cancer
    • Ariazi, E. A., Clark, G. M., and Mertz, J. E. (2002) Estrogen-related receptor α and estrogen-related receptor γ associate with unfavorable and favorable biomarkers, respectively, in human breast cancer. Cancer Res. 62, 6510-6518
    • (2002) Cancer Res. , vol.62 , pp. 6510-6518
    • Ariazi, E.A.1    Clark, G.M.2    Mertz, J.E.3
  • 5
    • 20444500826 scopus 로고    scopus 로고
    • Oestrogen receptorrelated receptorα (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression
    • Cavallini, A., Notarnicola, M., Giannini, R., Montemurro, S., Lorusso, D., Visconti, A., Minervini, F., and Caruso, M. G. (2005) Oestrogen receptorrelated receptorα (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression. Eur. J. Cancer 41, 1487-1494
    • (2005) Eur. J. Cancer , vol.41 , pp. 1487-1494
    • Cavallini, A.1    Notarnicola, M.2    Giannini, R.3    Montemurro, S.4    Lorusso, D.5    Visconti, A.6    Minervini, F.7    Caruso, M.G.8
  • 7
    • 21544454405 scopus 로고    scopus 로고
    • Expression of estrogen receptor-related receptors, a subfamily of orphan nuclear receptors, as new tumor biomarkers in ovarian cancer cells
    • Sun, P., Sehouli, J., Denkert, C., Mustea, A., Könsgen, D., Koch, I., Wei, L., and Lichtenegger, W. (2005) Expression of estrogen receptor-related receptors, a subfamily of orphan nuclear receptors, as new tumor biomarkers in ovarian cancer cells. J. Mol. Med. 83, 457-467
    • (2005) J. Mol. Med. , vol.83 , pp. 457-467
    • Sun, P.1    Sehouli, J.2    Denkert, C.3    Mustea, A.4    Könsgen, D.5    Koch, I.6    Wei, L.7    Lichtenegger, W.8
  • 11
    • 69949171075 scopus 로고    scopus 로고
    • Modulating estrogen receptor-related receptor-α activity inhibits cell proliferation
    • Bianco, S., Lanvin, O., Tribollet, V., Macari, C., North, S., and Vanacker, J. M. (2009) Modulating estrogen receptor-related receptor-α activity inhibits cell proliferation. J. Biol. Chem. 284, 23286-23292
    • (2009) J. Biol. Chem. , vol.284 , pp. 23286-23292
    • Bianco, S.1    Lanvin, O.2    Tribollet, V.3    Macari, C.4    North, S.5    Vanacker, J.M.6
  • 12
    • 71849115893 scopus 로고    scopus 로고
    • Identification and characterization of estrogen receptor-related receptorα and γ in human glioma and astrocytoma cells
    • Gandhari, M. K., Frazier, C. R., Hartenstein, J. S., Cloix, J. F., Bernier, M., and Wainer, I. W. (2010) Identification and characterization of estrogen receptor-related receptorα and γ in human glioma and astrocytoma cells. Mol. Cell. Endocrinol. 315, 314-318
    • (2010) Mol. Cell. Endocrinol. , vol.315 , pp. 314-318
    • Gandhari, M.K.1    Frazier, C.R.2    Hartenstein, J.S.3    Cloix, J.F.4    Bernier, M.5    Wainer, I.W.6
  • 13
    • 77649216353 scopus 로고    scopus 로고
    • Oestrogen-related receptor α inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production
    • Wang, J., Wang, Y., and Wong, C. (2010) Oestrogen-related receptor α inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production. Cell Prolif. 43, 103-113
    • (2010) Cell Prolif. , vol.43 , pp. 103-113
    • Wang, J.1    Wang, Y.2    Wong, C.3
  • 14
    • 80051890961 scopus 로고    scopus 로고
    • Estrogen-related receptor α expression and function are associated with vascular endothelial growth factor in human cervical cancer
    • Mori, T., Sawada, M., Kuroboshi, H., Tatsumi, H., Katsuyama, M., Iwasaku, K., and Kitawaki, J. (2011) Estrogen-related receptor α expression and function are associated with vascular endothelial growth factor in human cervical cancer. Int. J. Gynecol. Cancer 21, 609-615
    • (2011) Int. J. Gynecol. Cancer , vol.21 , pp. 609-615
    • Mori, T.1    Sawada, M.2    Kuroboshi, H.3    Tatsumi, H.4    Katsuyama, M.5    Iwasaku, K.6    Kitawaki, J.7
  • 15
    • 84862489809 scopus 로고    scopus 로고
    • MiR-137 targets estrogen-related receptor α and impairs the proliferative and migratory capacity of breast cancer cells
    • Zhao, Y., Li, Y., Lou, G., Zhao, L., Xu, Z., Zhang, Y., and He, F. (2012) miR-137 targets estrogen-related receptor α and impairs the proliferative and migratory capacity of breast cancer cells. PLoS One 7, e39102
    • (2012) PLoS One , vol.7 , pp. e39102
    • Zhao, Y.1    Li, Y.2    Lou, G.3    Zhao, L.4    Xu, Z.5    Zhang, Y.6    He, F.7
  • 16
    • 78650387482 scopus 로고    scopus 로고
    • Transcriptional control of the ERBB2 amplicon by ERRα and PGC-1β promotes mammary gland tumorigenesis
    • Deblois, G., Chahrour, G., Perry, M. C., Sylvain-Drolet, G., Muller, W. J., and Giguère, V. (2010) Transcriptional control of the ERBB2 amplicon by ERRα and PGC-1β promotes mammary gland tumorigenesis. Cancer Res. 70, 10277-10287
    • (2010) Cancer Res. , vol.70 , pp. 10277-10287
    • Deblois, G.1    Chahrour, G.2    Perry, M.C.3    Sylvain-Drolet, G.4    Muller, W.J.5    Giguère, V.6
  • 17
    • 84871715437 scopus 로고    scopus 로고
    • Oestrogen-related receptors in breast cancer: Control of cellular metabolism and beyond
    • Deblois, G., and Giguère, V. (2013) Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond. Nat. Rev. Cancer 13, 27-36
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 27-36
    • Deblois, G.1    Giguère, V.2
  • 18
    • 33846951523 scopus 로고    scopus 로고
    • Estrogen-related receptor α1 transcriptional activities are regulated in part via the ErbB2/HER2 signaling pathway
    • Ariazi, E. A., Kraus, R. J., Farrell, M. L., Jordan, V. C., and Mertz, J. E. (2007) Estrogen-related receptor α1 transcriptional activities are regulated in part via the ErbB2/HER2 signaling pathway. Mol. Cancer Res. 5, 71-85
    • (2007) Mol. Cancer Res. , vol.5 , pp. 71-85
    • Ariazi, E.A.1    Kraus, R.J.2    Farrell, M.L.3    Jordan, V.C.4    Mertz, J.E.5
  • 19
    • 84875909085 scopus 로고    scopus 로고
    • Molecular and genetic cross-talks betweenmTORand ERRα are key determinants of rapamycininduced nonalcoholic fatty liver
    • Chaveroux, C., Eichner, L. J., Dufour, C. R., Shatnawi, A., Khoutorsky, A., Bourque, G., Sonenberg, N., and Giguère, V. (2013) Molecular and genetic cross-talks betweenmTORand ERRα are key determinants of rapamycininduced nonalcoholic fatty liver. Cell Metab. 17, 586-598
    • (2013) Cell Metab. , vol.17 , pp. 586-598
    • Chaveroux, C.1    Eichner, L.J.2    Dufour, C.R.3    Shatnawi, A.4    Khoutorsky, A.5    Bourque, G.6    Sonenberg, N.7    Giguère, V.8
  • 20
    • 2442607758 scopus 로고    scopus 로고
    • A polymorphic autoregulatory hormone response element in the human estrogen-related receptor α (ERRα) promoter dictates peroxisome proliferator-activated receptor γ coactivator-1α control of ERRα expression
    • Laganière, J., Tremblay, G. B., Dufour, C. R., Giroux, S., Rousseau, F., and Giguère, V., (2004) A polymorphic autoregulatory hormone response element in the human estrogen-related receptor α (ERRα) promoter dictates peroxisome proliferator-activated receptor γ coactivator-1α control of ERRα expression. J. Biol. Chem. 279, 18504-18510
    • (2004) J. Biol. Chem. , vol.279 , pp. 18504-18510
    • Laganière, J.1    Tremblay, G.B.2    Dufour, C.R.3    Giroux, S.4    Rousseau, F.5    Giguère, V.6
  • 21
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 23
    • 84872058567 scopus 로고    scopus 로고
    • Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: Implications for cancer therapeutics
    • Rather, M. I., Nagashri, M. N., Swamy, S. S., Gopinath, K. S., and Kumar, A. (2013) Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics. J. Biol. Chem. 288, 608-618
    • (2013) J. Biol. Chem. , vol.288 , pp. 608-618
    • Rather, M.I.1    Nagashri, M.N.2    Swamy, S.S.3    Gopinath, K.S.4    Kumar, A.5
  • 24
    • 79960799901 scopus 로고    scopus 로고
    • Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer
    • Chang, C. J., Hsu, C. C., Chang, C. H., Tsai, L. L., Chang, Y. C., Lu, S. W., Yu, C. H., Huang, H. S., Wang, J. J., and Tsai, C. H. (2011) Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer. Oncol. Rep. 26, 1003-1010
    • (2011) Oncol. Rep. , vol.26 , pp. 1003-1010
    • Chang, C.J.1    Hsu, C.C.2    Chang, C.H.3    Tsai, L.L.4    Chang, Y.C.5    Lu, S.W.6    Yu, C.H.7    Huang, H.S.8    Wang, J.J.9    Tsai, C.H.10
  • 27
  • 28
    • 84885065624 scopus 로고    scopus 로고
    • First microRNA mimic enters clinic
    • Bouchie, A. (2013) First microRNA mimic enters clinic. Nat. Biotechnol. 31, 577-577
    • (2013) Nat. Biotechnol. , vol.31 , pp. 577-577
    • Bouchie, A.1
  • 30
    • 0030692092 scopus 로고    scopus 로고
    • TNM classification of malignant tumors, fifth edition. Union Internationale Centre le Cancer and the American Joint Committee on Cancer
    • Sobin, L. H., and Fleming, I. D. (1997) TNM classification of malignant tumors, fifth edition. Union Internationale Centre le Cancer and the American Joint Committee on Cancer. Cancer 80, 1803-1804
    • (1997) Cancer , vol.80 , pp. 1803-1804
    • Sobin, L.H.1    Fleming, I.D.2
  • 31
    • 44349101865 scopus 로고    scopus 로고
    • MiR-Q: A novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample
    • Sharbati-Tehrani, S., Kutz-Lohroff, B., Bergbauer, R., Scholven, J., and Einspanier, R. (2008) miR-Q: a novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample. BMC Mol. Biol. 9, 34
    • (2008) BMC Mol. Biol. , vol.9 , pp. 34
    • Sharbati-Tehrani, S.1    Kutz-Lohroff, B.2    Bergbauer, R.3    Scholven, J.4    Einspanier, R.5
  • 32
    • 84894254202 scopus 로고    scopus 로고
    • MiR-125a regulates cell cycle, proliferation, and apoptosis by targeting the ErbB pathway in acute myeloid leukemia
    • Ufkin, M. L., Peterson, S., Yang, X., Driscoll, H., Duarte, C., and Sathyanarayana, P. (2014) miR-125a regulates cell cycle, proliferation, and apoptosis by targeting the ErbB pathway in acute myeloid leukemia. Leuk. Res. 38, 402-410
    • (2014) Leuk. Res. , vol.38 , pp. 402-410
    • Ufkin, M.L.1    Peterson, S.2    Yang, X.3    Driscoll, H.4    Duarte, C.5    Sathyanarayana, P.6
  • 33
    • 84874609790 scopus 로고    scopus 로고
    • Primary microcephaly gene MCPH1 shows signatures of tumor suppressors and is regulated by miR-27a in oral squamous cell carcinoma
    • Venkatesh, T., Nagashri, M. N., Swamy, S. S., Mohiyuddin, S. M., Gopinath, K. S., and Kumar, A. (2013) Primary microcephaly gene MCPH1 shows signatures of tumor suppressors and is regulated by miR-27a in oral squamous cell carcinoma. PloS One 8, e54643
    • (2013) PloS One , vol.8 , pp. e54643
    • Venkatesh, T.1    Nagashri, M.N.2    Swamy, S.S.3    Mohiyuddin, S.M.4    Gopinath, K.S.5    Kumar, A.6
  • 36
    • 77950584927 scopus 로고    scopus 로고
    • MicroRNA-125a represses cell growth by targeting HuR in breast cancer
    • Guo, X., Wu, Y., and Hartley, R. S. (2009) MicroRNA-125a represses cell growth by targeting HuR in breast cancer. RNA Biol. 6, 575-583
    • (2009) RNA Biol. , vol.6 , pp. 575-583
    • Guo, X.1    Wu, Y.2    Hartley, R.S.3
  • 37
    • 70349229606 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-regulated miR-125a-5p-a metastatic inhibitor of lung cancer
    • Wang, G., Mao, W., Zheng, S., and Ye, J. (2009) Epidermal growth factor receptor-regulated miR-125a-5p-a metastatic inhibitor of lung cancer. FEBS J. 276, 5571-5578
    • (2009) FEBS J. , vol.276 , pp. 5571-5578
    • Wang, G.1    Mao, W.2    Zheng, S.3    Ye, J.4
  • 38
    • 79955513982 scopus 로고    scopus 로고
    • MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab
    • Nishida, N., Mimori, K., Fabbri, M., Yokobori, T., Sudo, T., Tanaka, F., Shibata, K., Ishii, H., Doki, Y., and Mori, M. (2011) MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab. Clin. Cancer Res. 17, 2725-2733
    • (2011) Clin. Cancer Res. , vol.17 , pp. 2725-2733
    • Nishida, N.1    Mimori, K.2    Fabbri, M.3    Yokobori, T.4    Sudo, T.5    Tanaka, F.6    Shibata, K.7    Ishii, H.8    Doki, Y.9    Mori, M.10
  • 39
    • 70350728790 scopus 로고    scopus 로고
    • The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells
    • Cowden Dahl, K. D., Dahl, R., Kruichak, J. N., and Hudson, L. G. (2009) The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells. Neoplasia 11, 1208-1215
    • (2009) Neoplasia , vol.11 , pp. 1208-1215
    • Cowden Dahl, K.D.1    Dahl, R.2    Kruichak, J.N.3    Hudson, L.G.4
  • 40
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • Kozaki, K., Imoto, I., Mogi, S., Omura, K., and Inazawa, J. (2008) Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res. 68, 2094-2105
    • (2008) Cancer Res. , vol.68 , pp. 2094-2105
    • Kozaki, K.1    Imoto, I.2    Mogi, S.3    Omura, K.4    Inazawa, J.5
  • 42
    • 84863111015 scopus 로고    scopus 로고
    • Ectopic expression of miR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF
    • Bi, Q., Tang, S., Xia, L., Du, R., Fan, R., Gao, L., Jin, J., Liang, S., Chen, Z., and Xu, G. (2012) Ectopic expression of miR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. PLoS One 7, e40169
    • (2012) PLoS One , vol.7 , pp. e40169
    • Bi, Q.1    Tang, S.2    Xia, L.3    Du, R.4    Fan, R.5    Gao, L.6    Jin, J.7    Liang, S.8    Chen, Z.9    Xu, G.10
  • 43
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • Scott, G. K., Goga, A., Bhaumik, D., Berger, C. E., Sullivan, C. S., and Benz, C. C. (2007) Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J. Biol. Chem. 282, 1479-1486
    • (2007) J. Biol. Chem. , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 44
    • 84868120534 scopus 로고    scopus 로고
    • A regulatory loop involving Dies1 and miR-125a controls BMP4 signaling in mouse embryonic stem cells
    • Parisi, S., Battista, M., Musto, A., Navarra, A., Tarantino, C., and Russo, T. (2012) A regulatory loop involving Dies1 and miR-125a controls BMP4 signaling in mouse embryonic stem cells. FASEB J. 26, 3957-3968
    • (2012) FASEB J. , vol.26 , pp. 3957-3968
    • Parisi, S.1    Battista, M.2    Musto, A.3    Navarra, A.4    Tarantino, C.5    Russo, T.6
  • 45
    • 68849108383 scopus 로고    scopus 로고
    • Estrogen-related receptor α (ERRα) inverse agonist XCT-790 induces cell death in chemotherapeutic resistant cancer cells
    • Wu, F., Wang, J., Wang, Y., Kwok, T. T., Kong, S. K., and Wong, C. (2009) Estrogen-related receptor α (ERRα) inverse agonist XCT-790 induces cell death in chemotherapeutic resistant cancer cells. Chem. Biol. Interact. 181, 236-242
    • (2009) Chem. Biol. Interact. , vol.181 , pp. 236-242
    • Wu, F.1    Wang, J.2    Wang, Y.3    Kwok, T.T.4    Kong, S.K.5    Wong, C.6
  • 46
    • 79958035502 scopus 로고    scopus 로고
    • Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic ras-dependent anchorage-independent growth
    • Fisher, K. W., Das, B., Kortum, R. L., Chaika, O. V., and Lewis, R. E. (2011) Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic ras-dependent anchorage-independent growth. Mol. Cell. Biol. 31, 2453-2461
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 2453-2461
    • Fisher, K.W.1    Das, B.2    Kortum, R.L.3    Chaika, O.V.4    Lewis, R.E.5
  • 47
    • 84897574523 scopus 로고    scopus 로고
    • Targeting estrogen-related receptor α inhibits epithelial to mesenchymal transition and stem cell properties of ovarian cancer cells
    • Lam, S. S., Mak, A. S., Yam, J. W., Cheung, A. N., Ngan, H. Y., and Wong, A. S. (2014) Targeting estrogen-related receptor α inhibits epithelial to mesenchymal transition and stem cell properties of ovarian cancer cells. Mol. Ther. 22, 743-751
    • (2014) Mol. Ther. , vol.22 , pp. 743-751
    • Lam, S.S.1    Mak, A.S.2    Yam, J.W.3    Cheung, A.N.4    Ngan, H.Y.5    Wong, A.S.6
  • 48
    • 2942726272 scopus 로고    scopus 로고
    • Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells
    • Ouko, L., Ziegler, T. R., Gu, L. H., Eisenberg, L. M., and Yang, V. W. (2004) Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells. J. Biol. Chem. 279, 26707-26715
    • (2004) J. Biol. Chem. , vol.279 , pp. 26707-26715
    • Ouko, L.1    Ziegler, T.R.2    Gu, L.H.3    Eisenberg, L.M.4    Yang, V.W.5
  • 50
    • 77956901498 scopus 로고    scopus 로고
    • The promise of microRNA replacement therapy
    • Bader, A. G., Brown, D., and Winkler, M. (2010) The promise of microRNA replacement therapy. Cancer Res. 70, 7027-7030
    • (2010) Cancer Res. , vol.70 , pp. 7027-7030
    • Bader, A.G.1    Brown, D.2    Winkler, M.3


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