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Volumn 8, Issue 3, 2013, Pages

Primary Microcephaly Gene MCPH1 Shows Signatures of Tumor Suppressors and Is Regulated by miR-27a in Oral Squamous Cell Carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

MICROCEPHALIN 1; MICRORNA; MICRORNA 27A; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; MCPH1 PROTEIN, HUMAN; MIRN27 MICRORNA, HUMAN; NERVE PROTEIN;

EID: 84874609790     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054643     Document Type: Article
Times cited : (40)

References (55)
  • 1
    • 0037821661 scopus 로고    scopus 로고
    • Multiple tumor suppressor pathways negatively regulate telomerase
    • Lin SY, Elledge SJ, (2003) Multiple tumor suppressor pathways negatively regulate telomerase. Cell 113: 881-889.
    • (2003) Cell , vol.113 , pp. 881-889
    • Lin, S.Y.1    Elledge, S.J.2
  • 2
    • 0036302105 scopus 로고    scopus 로고
    • Identification of microcephalin, a protein implicated in determining the size of the human brain
    • Jackson AP, Eastwood H, Bell SM, Adu J, Toomes C, et al. (2002) Identification of microcephalin, a protein implicated in determining the size of the human brain. Am J Hum Genet 71: 136-142.
    • (2002) Am J Hum Genet , vol.71 , pp. 136-142
    • Jackson, A.P.1    Eastwood, H.2    Bell, S.M.3    Adu, J.4    Toomes, C.5
  • 3
    • 3242657086 scopus 로고    scopus 로고
    • Mutations in microcephalin cause aberrant regulation of chromosome condensation
    • Trimborn M, Bell SM, Felix C, Rashid Y, Jafri H, et al. (2004) Mutations in microcephalin cause aberrant regulation of chromosome condensation. Am J Hum Genet 75: 261-266.
    • (2004) Am J Hum Genet , vol.75 , pp. 261-266
    • Trimborn, M.1    Bell, S.M.2    Felix, C.3    Rashid, Y.4    Jafri, H.5
  • 4
    • 33746857684 scopus 로고    scopus 로고
    • BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer
    • Rai R, Dai H, Multani AS, Li K, Chin K, et al. (2006) BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer. Cancer Cell 10: 145-157.
    • (2006) Cancer Cell , vol.10 , pp. 145-157
    • Rai, R.1    Dai, H.2    Multani, A.S.3    Li, K.4    Chin, K.5
  • 5
    • 70349916401 scopus 로고    scopus 로고
    • BRIT1/MCPH1 is a multifunctional DNA damage responsive protein mediating DNA repair-associated chromatin remodeling
    • Peng G, Lin SY, (2009) BRIT1/MCPH1 is a multifunctional DNA damage responsive protein mediating DNA repair-associated chromatin remodeling. Cell Cycle 8: 3071-3072.
    • (2009) Cell Cycle , vol.8 , pp. 3071-3072
    • Peng, G.1    Lin, S.Y.2
  • 6
    • 57649223685 scopus 로고    scopus 로고
    • Microcephalin/MCPH1 associates with the condensin II complex to function in homologous recombination repair
    • Wood JL, Liang Y, Li K, Chen J, (2008) Microcephalin/MCPH1 associates with the condensin II complex to function in homologous recombination repair. J Biol Chem 283: 29586-29592.
    • (2008) J Biol Chem , vol.283 , pp. 29586-29592
    • Wood, J.L.1    Liang, Y.2    Li, K.3    Chen, J.4
  • 7
    • 51049100399 scopus 로고    scopus 로고
    • MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis
    • Yang SZ, Lin FT, Lin WC, (2008) MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis. EMBO Rep 9: 907-915.
    • (2008) EMBO Rep , vol.9 , pp. 907-915
    • Yang, S.Z.1    Lin, F.T.2    Lin, W.C.3
  • 8
    • 47749153760 scopus 로고    scopus 로고
    • Differential regulation of centrosome integrity by DNA damage response proteins
    • Rai R, Phadnis A, Haralkar S, Badwe RA, Dai H, et al. (2008) Differential regulation of centrosome integrity by DNA damage response proteins. Cell Cycle 7: 2225-2233.
    • (2008) Cell Cycle , vol.7 , pp. 2225-2233
    • Rai, R.1    Phadnis, A.2    Haralkar, S.3    Badwe, R.A.4    Dai, H.5
  • 9
    • 67649576600 scopus 로고    scopus 로고
    • Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1
    • Tibelius A, Marhold J, Zentgraf H, Heilig CE, Neitzel H, et al. (2009) Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1. J Cell Biol 185: 1149-1157.
    • (2009) J Cell Biol , vol.185 , pp. 1149-1157
    • Tibelius, A.1    Marhold, J.2    Zentgraf, H.3    Heilig, C.E.4    Neitzel, H.5
  • 10
    • 77957793995 scopus 로고    scopus 로고
    • MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification
    • Brown JA, Bourke E, Liptrot C, Dockery P, Morrison CG, (2010) MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification. Oncogene 29: 5537-5544.
    • (2010) Oncogene , vol.29 , pp. 5537-5544
    • Brown, J.A.1    Bourke, E.2    Liptrot, C.3    Dockery, P.4    Morrison, C.G.5
  • 11
    • 76749170775 scopus 로고    scopus 로고
    • BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice
    • Liang Y, Gao H, Lin SY, Peng G, Huang X, et al. (2010) BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice. PLoS Genet 6: e1000826.
    • (2010) PLoS Genet , vol.6
    • Liang, Y.1    Gao, H.2    Lin, S.Y.3    Peng, G.4    Huang, X.5
  • 12
    • 77949532680 scopus 로고    scopus 로고
    • Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function
    • Trimborn M, Ghani M, Walther DJ, Dopatka M, Dutrannoy V, et al. (2010) Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function. PLoS ONE 5: e9242.
    • (2010) PLoS ONE , vol.5
    • Trimborn, M.1    Ghani, M.2    Walther, D.J.3    Dopatka, M.4    Dutrannoy, V.5
  • 13
    • 80455177095 scopus 로고    scopus 로고
    • MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway
    • Gruber R, Zhou Z, Sukchev M, Joerss T, Frappart PO, et al. (2011) MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway. Nat Cell Biol 13: 1325-1334.
    • (2011) Nat Cell Biol , vol.13 , pp. 1325-1334
    • Gruber, R.1    Zhou, Z.2    Sukchev, M.3    Joerss, T.4    Frappart, P.O.5
  • 14
    • 0000377414 scopus 로고    scopus 로고
    • Deletion mapping defines three discrete areas of allelic imbalance on chromosome arm 8p in oral and oropharyngeal squamous cell carcinomas
    • Wu CL, Roz L, Sloan P, Read AP, Holland S, et al. (1997) Deletion mapping defines three discrete areas of allelic imbalance on chromosome arm 8p in oral and oropharyngeal squamous cell carcinomas. Genes Chromosomes Cancer 20: 347-353.
    • (1997) Genes Chromosomes Cancer , vol.20 , pp. 347-353
    • Wu, C.L.1    Roz, L.2    Sloan, P.3    Read, A.P.4    Holland, S.5
  • 15
    • 34047171368 scopus 로고    scopus 로고
    • Frequent loss of heterozygosity in two distinct regions, 8p23.1 and 8p22, in hepatocellular carcinoma
    • Lu T, Hano H, Meng C, Nagatsuma K, Chiba S, et al. (2007) Frequent loss of heterozygosity in two distinct regions, 8p23.1 and 8p22, in hepatocellular carcinoma. World J Gastroenterol 13: 1090-1097.
    • (2007) World J Gastroenterol , vol.13 , pp. 1090-1097
    • Lu, T.1    Hano, H.2    Meng, C.3    Nagatsuma, K.4    Chiba, S.5
  • 16
    • 77957197261 scopus 로고    scopus 로고
    • Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer
    • Bilbao C, Ramirez R, Rodriguez G, Falcon O, Leon L, et al. (2010) Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer. Eur J Cancer 46: 2821-2827.
    • (2010) Eur J Cancer , vol.46 , pp. 2821-2827
    • Bilbao, C.1    Ramirez, R.2    Rodriguez, G.3    Falcon, O.4    Leon, L.5
  • 17
    • 79958279660 scopus 로고    scopus 로고
    • Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation
    • Richardson J, Shaaban AM, Kamal M, Alisary R, Walker C, et al. (2011) Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation. Breast Cancer Res Treat 127: 639-648.
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 639-648
    • Richardson, J.1    Shaaban, A.M.2    Kamal, M.3    Alisary, R.4    Walker, C.5
  • 18
    • 0030692092 scopus 로고    scopus 로고
    • TNM classification of malignant tumors, fifth edition. Union Internationale Contre le Cancer and the American Joint Committee on Cancer
    • Sobin LH, Fleming ID, (1997) TNM classification of malignant tumors, fifth edition. Union Internationale Contre le Cancer and the American Joint Committee on Cancer. Cancer 80: 1803-1804.
    • (1997) Cancer , vol.80 , pp. 1803-1804
    • Sobin, L.H.1    Fleming, I.D.2
  • 19
    • 34447302548 scopus 로고    scopus 로고
    • The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines
    • White JS, Weissfeld JL, Ragin CC, Rossie KM, Martin CL, et al. (2007) The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines. Oral Oncol 43: 701-712.
    • (2007) Oral Oncol , vol.43 , pp. 701-712
    • White, J.S.1    Weissfeld, J.L.2    Ragin, C.C.3    Rossie, K.M.4    Martin, C.L.5
  • 20
    • 0031714587 scopus 로고    scopus 로고
    • Molecular characterization and delineation of subtle deletions in de novo "balanced" chromosomal rearrangements
    • Kumar A, Becker LA, Depinet TW, Haren JM, Kurtz CL, et al. (1998) Molecular characterization and delineation of subtle deletions in de novo "balanced" chromosomal rearrangements. Hum Genet 103: 173-178.
    • (1998) Hum Genet , vol.103 , pp. 173-178
    • Kumar, A.1    Becker, L.A.2    Depinet, T.W.3    Haren, J.M.4    Kurtz, C.L.5
  • 21
    • 0028340435 scopus 로고
    • Loss of chromosome arm 8p loci in prostate cancer: mapping by quantitative allelic imbalance
    • MacGrogan D, Levy A, Bostwick D, Wagner M, Wells D, et al. (1994) Loss of chromosome arm 8p loci in prostate cancer: mapping by quantitative allelic imbalance. Genes Chromosomes Cancer 10: 151-159.
    • (1994) Genes Chromosomes Cancer , vol.10 , pp. 151-159
    • MacGrogan, D.1    Levy, A.2    Bostwick, D.3    Wagner, M.4    Wells, D.5
  • 22
    • 45949107072 scopus 로고    scopus 로고
    • Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma
    • Chakraborty S, Mohiyuddin SM, Gopinath KS, Kumar A, (2008) Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma. BMC Cancer 8: 163.
    • (2008) BMC Cancer , vol.8 , pp. 163
    • Chakraborty, S.1    Mohiyuddin, S.M.2    Gopinath, K.S.3    Kumar, A.4
  • 23
    • 29244459423 scopus 로고    scopus 로고
    • Choice of endogenous control for gene expression in non small cell lung cancer
    • Liu DW, Chen ST, Liu HP, (2005) Choice of endogenous control for gene expression in non small cell lung cancer. Eur Respir J 26: 1002-1008.
    • (2005) Eur Respir J , vol.26 , pp. 1002-1008
    • Liu, D.W.1    Chen, S.T.2    Liu, H.P.3
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 28244435863 scopus 로고    scopus 로고
    • Identification of a candidate tumor suppressor gene RHOBTB1 located at a novel allelic loss region 10q21 in head and neck cancer
    • Beder LB, Gunduz M, Ouchida M, Gunduz E, Sakai A, et al. (2006) Identification of a candidate tumor suppressor gene RHOBTB1 located at a novel allelic loss region 10q21 in head and neck cancer. J Cancer Res Clin Oncol 132: 19-27.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 19-27
    • Beder, L.B.1    Gunduz, M.2    Ouchida, M.3    Gunduz, E.4    Sakai, A.5
  • 26
    • 0035111058 scopus 로고    scopus 로고
    • Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients
    • Simmons ML, Lamborn KR, Takahashi M, Chen P, Israel MA, et al. (2001) Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients. Cancer Res 61: 1122-1128.
    • (2001) Cancer Res , vol.61 , pp. 1122-1128
    • Simmons, M.L.1    Lamborn, K.R.2    Takahashi, M.3    Chen, P.4    Israel, M.A.5
  • 27
    • 52949106845 scopus 로고    scopus 로고
    • Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS
    • Bajaj V, Singhmar P, Kumar A, (2008) Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS. Gene 424: 40-47.
    • (2008) Gene , vol.424 , pp. 40-47
    • Bajaj, V.1    Singhmar, P.2    Kumar, A.3
  • 28
    • 6444233371 scopus 로고    scopus 로고
    • The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line
    • Baumann Kubetzko FB, Di Paolo C, Maag C, Meier R, Schafer BW, et al. (2004) The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line. Carcinogenesis 25: 1839-1846.
    • (2004) Carcinogenesis , vol.25 , pp. 1839-1846
    • Baumann Kubetzko, F.B.1    Di Paolo, C.2    Maag, C.3    Meier, R.4    Schafer, B.W.5
  • 29
    • 33748424414 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is involved in S100A2-mediated tumor suppression in squamous cell carcinoma
    • Tsai WC, Tsai ST, Jin YT, Wu LW, (2006) Cyclooxygenase-2 is involved in S100A2-mediated tumor suppression in squamous cell carcinoma. Mol Cancer Res 4: 539-547.
    • (2006) Mol Cancer Res , vol.4 , pp. 539-547
    • Tsai, W.C.1    Tsai, S.T.2    Jin, Y.T.3    Wu, L.W.4
  • 30
    • 0032957639 scopus 로고    scopus 로고
    • Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis
    • Wang W, Malcolm BA, (1999) Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis. Biotechniques 26: 680-682.
    • (1999) Biotechniques , vol.26 , pp. 680-682
    • Wang, W.1    Malcolm, B.A.2
  • 31
    • 44349101865 scopus 로고    scopus 로고
    • miR-Q: a novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample
    • Sharbati-Tehrani S, Kutz-Lohroff B, Bergbauer R, Scholven J, Einspanier R, (2008) miR-Q: a novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample. BMC Mol Biol 9: 34.
    • (2008) BMC Mol Biol , vol.9 , pp. 34
    • Sharbati-Tehrani, S.1    Kutz-Lohroff, B.2    Bergbauer, R.3    Scholven, J.4    Einspanier, R.5
  • 32
    • 74549200943 scopus 로고    scopus 로고
    • Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: modification of the two-hit hypothesis
    • Pan S, Dong Q, Sun LS, Li TJ, (2010) Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: modification of the two-hit hypothesis. Clin Cancer Res 16: 442-450.
    • (2010) Clin Cancer Res , vol.16 , pp. 442-450
    • Pan, S.1    Dong, Q.2    Sun, L.S.3    Li, T.J.4
  • 33
    • 30844470110 scopus 로고    scopus 로고
    • The first missense alteration in the MCPH1 gene causes autosomal recessive microcephaly with an extremely mild cellular and clinical phenotype
    • Trimborn M, Richter R, Sternberg N, Gavvovidis I, Schindler D, et al. (2005) The first missense alteration in the MCPH1 gene causes autosomal recessive microcephaly with an extremely mild cellular and clinical phenotype. Hum Mutat 26: 496.
    • (2005) Hum Mutat , vol.26 , pp. 496
    • Trimborn, M.1    Richter, R.2    Sternberg, N.3    Gavvovidis, I.4    Schindler, D.5
  • 35
    • 75449091571 scopus 로고    scopus 로고
    • Craniosyntosis-microcephaly with chromosomal breakage and other abnormalities is caused by a truncating MCPH1 mutation and is allelic to premature chromosomal condensation syndrome and primary autosomal recessive microcephaly type 1
    • Farooq M, Baig S, Tommerup N, Kjar KW, (2010) Craniosyntosis-microcephaly with chromosomal breakage and other abnormalities is caused by a truncating MCPH1 mutation and is allelic to premature chromosomal condensation syndrome and primary autosomal recessive microcephaly type 1. Am J Med Genet A 152A: 495-497.
    • (2010) Am J Med Genet A , vol.152 A , pp. 495-497
    • Farooq, M.1    Baig, S.2    Tommerup, N.3    Kjar, K.W.4
  • 37
    • 84862498488 scopus 로고    scopus 로고
    • Two missense mutations in the primary autosomal recessive microcephaly gene MCPH1 disrupt the function of the highly conserved N-terminal BRCT domain of microcephalin
    • Ghani-Kakhki M, Robinson PN, Morlot S, Mitter D, Trimborn M, et al. (2012) Two missense mutations in the primary autosomal recessive microcephaly gene MCPH1 disrupt the function of the highly conserved N-terminal BRCT domain of microcephalin. Mol Syndromol 3: 6-13.
    • (2012) Mol Syndromol , vol.3 , pp. 6-13
    • Ghani-Kakhki, M.1    Robinson, P.N.2    Morlot, S.3    Mitter, D.4    Trimborn, M.5
  • 38
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future
    • Esteller M, (2002) CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 21: 5427-5440.
    • (2002) Oncogene , vol.21 , pp. 5427-5440
    • Esteller, M.1
  • 39
    • 78649251520 scopus 로고    scopus 로고
    • The origins and implications of intra-tumor heterogeneity
    • Michor F, Polyak K, (2010) The origins and implications of intra-tumor heterogeneity. Cancer Prev Res 3: 1361-1364.
    • (2010) Cancer Prev Res , vol.3 , pp. 1361-1364
    • Michor, F.1    Polyak, K.2
  • 41
    • 84856086311 scopus 로고    scopus 로고
    • Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression
    • Shi L, Su B, (2012) Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression. FEBS J 279: 491-503.
    • (2012) FEBS J , vol.279 , pp. 491-503
    • Shi, L.1    Su, B.2
  • 42
    • 5044239253 scopus 로고    scopus 로고
    • Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage
    • Hague A, Eveson JW, MacFarlane M, Huntley S, Janghra N, et al. (2004) Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage. J Pathol 204: 175-182.
    • (2004) J Pathol , vol.204 , pp. 175-182
    • Hague, A.1    Eveson, J.W.2    MacFarlane, M.3    Huntley, S.4    Janghra, N.5
  • 43
    • 54949084695 scopus 로고    scopus 로고
    • Evaluation of caspase-3 and caspase-8 deregulation in tongue squamous cell carcinoma, based on immunohistochemistry and computerised image analysis
    • Andressakis D, Lazaris AC, Tsiambas E, Kavantzas N, Rapidis A, et al. (2008) Evaluation of caspase-3 and caspase-8 deregulation in tongue squamous cell carcinoma, based on immunohistochemistry and computerised image analysis. J Laryngol Otol 122: 1213-1218.
    • (2008) J Laryngol Otol , vol.122 , pp. 1213-1218
    • Andressakis, D.1    Lazaris, A.C.2    Tsiambas, E.3    Kavantzas, N.4    Rapidis, A.5
  • 44
    • 58449103581 scopus 로고    scopus 로고
    • Cell line cross-contamination: KB is not an oral squamous cell carcinoma cell line
    • Jiang L, Zeng X, Wang Z, Chen Q, (2009) Cell line cross-contamination: KB is not an oral squamous cell carcinoma cell line. Eur J Oral Sci 117: 90-91.
    • (2009) Eur J Oral Sci , vol.117 , pp. 90-91
    • Jiang, L.1    Zeng, X.2    Wang, Z.3    Chen, Q.4
  • 45
    • 34249856066 scopus 로고    scopus 로고
    • Distance constraints between microRNA target sites dictate efficacy and cooperativity
    • Saetrom P, Heale BS, Snove O, Aagaard L, Alluin J, et al. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Res 35: 2333-2342.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2333-2342
    • Saetrom, P.1    Heale, B.S.2    Snove, O.3    Aagaard, L.4    Alluin, J.5
  • 46
    • 76749160835 scopus 로고    scopus 로고
    • Comprehensive microRNA profiling for head and neck squamous cell carcinomas
    • Hui AB, Lenarduzzi M, Krushel T, Waldron L, Pintilie M, et al. (2010) Comprehensive microRNA profiling for head and neck squamous cell carcinomas. Clin Cancer Res 16: 1129-1139.
    • (2010) Clin Cancer Res , vol.16 , pp. 1129-1139
    • Hui, A.B.1    Lenarduzzi, M.2    Krushel, T.3    Waldron, L.4    Pintilie, M.5
  • 47
    • 77957948990 scopus 로고    scopus 로고
    • miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2
    • Ma Y, Yu S, Zhao W, Lu Z, Chen J, (2010) miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2. Cancer Lett 298: 150-158.
    • (2010) Cancer Lett , vol.298 , pp. 150-158
    • Ma, Y.1    Yu, S.2    Zhao, W.3    Lu, Z.4    Chen, J.5
  • 48
    • 27144540976 scopus 로고    scopus 로고
    • Centrosome amplification, chromosome instability and cancer development
    • Fukasawa K, (2005) Centrosome amplification, chromosome instability and cancer development. Cancer Lett 230: 6-19.
    • (2005) Cancer Lett , vol.230 , pp. 6-19
    • Fukasawa, K.1
  • 49
    • 62649118818 scopus 로고    scopus 로고
    • Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly
    • Kumar A, Girimaji SC, Duvvari MR, Blanton SH, (2009) Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly. Am J Hum Genet 84: 286-290.
    • (2009) Am J Hum Genet , vol.84 , pp. 286-290
    • Kumar, A.1    Girimaji, S.C.2    Duvvari, M.R.3    Blanton, S.H.4
  • 51
    • 80054925777 scopus 로고    scopus 로고
    • Mutations in WDR62, encoding a centrosomal and nuclear protein, in Indian primary microcephaly families with cortical malformations
    • Bhat V, Girimaji SC, Mohan G, Arvinda HR, Singhmar P, et al. (2011) Mutations in WDR62, encoding a centrosomal and nuclear protein, in Indian primary microcephaly families with cortical malformations. Clin Genet 80: 532-540.
    • (2011) Clin Genet , vol.80 , pp. 532-540
    • Bhat, V.1    Girimaji, S.C.2    Mohan, G.3    Arvinda, H.R.4    Singhmar, P.5
  • 52
    • 84860757548 scopus 로고    scopus 로고
    • A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function
    • Hussain MS, Baig SM, Neumann S, Nurnberg G, Farooq M, et al. (2012) A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet 90: 871-878.
    • (2012) Am J Hum Genet , vol.90 , pp. 871-878
    • Hussain, M.S.1    Baig, S.M.2    Neumann, S.3    Nurnberg, G.4    Farooq, M.5
  • 53
    • 78651248502 scopus 로고    scopus 로고
    • CEP152 is a genome maintenance protein disrupted in Seckel syndrome
    • Kalay E, Yigit G, Aslan Y, Brown KE, Pohl E, et al. (2011) CEP152 is a genome maintenance protein disrupted in Seckel syndrome. Nat Genet 43: 23-26.
    • (2011) Nat Genet , vol.43 , pp. 23-26
    • Kalay, E.1    Yigit, G.2    Aslan, Y.3    Brown, K.E.4    Pohl, E.5
  • 54
    • 85027955669 scopus 로고    scopus 로고
    • ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target
    • Bikeye SN, Colin C, Marie Y, Vampouille R, Ravassard P, et al. (2010) ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target. Cancer Cell Int 10: 1.
    • (2010) Cancer Cell Int , vol.10 , pp. 1
    • Bikeye, S.N.1    Colin, C.2    Marie, Y.3    Vampouille, R.4    Ravassard, P.5
  • 55
    • 0037214560 scopus 로고    scopus 로고
    • Gene therapy for the treatment of oral squamous cell carcinoma
    • Xi S, Grandis JR, (2003) Gene therapy for the treatment of oral squamous cell carcinoma. J Dent Res 82: 11-16.
    • (2003) J Dent Res , vol.82 , pp. 11-16
    • Xi, S.1    Grandis, J.R.2


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