Estrogen-related receptor α (ERRα) inverse agonist XCT-790 induces cell death in chemotherapeutic resistant cancer cells

Chemico-Biological Interactions

Volumn 181, Issue 2, 2009, Pages 236-242

  Wu, Feng ^a   Wang, Junjian ^a   Wang, Yanfei ^a   Kwok, Tim Tak ^b   Kong, Siu Kai ^b   Wong, Chiwai ^a  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Estrogen related receptor alpha (ERR ); Multi drug resistance (MDR); Reactive oxygen species (ROS)

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; DOXORUBICIN; ESTROGEN RELATED RECEPTOR ALPHA; PACLITAXEL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; XCT 790;

ARTICLE; CANCER CELL DESTRUCTION; CELL DEATH; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION;

APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; DNA, MITOCHONDRIAL; DRUG RESISTANCE, NEOPLASM; HUMANS; MITOCHONDRIA; NITRILES; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; RECEPTORS, ESTROGEN; THIAZOLES;

TETRA;

EID: 68849108383     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.05.008     Document Type: Article

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