Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response

Aging Cell

Volumn 13, Issue 6, 2014, Pages 1091-1094

  Valapala, Mallika ^a   Edwards, Malia ^a   Hose, Stacey ^a   Grebe, Rhonda ^a   Bhutto, Imran A ^a   Cano, Marisol ^a   Berger, Thorsten ^b   Mak, Tak W ^b   Wawrousek, Eric ^c   Handa, James T ^a   Lutty, Gerard A ^a   Samuel Zigler, J ^a   Sinha, Debasish ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c NATIONAL EYE INSTITUTE   (United States)

Author keywords

Age related macular degeneration; Cryba1 cKO mice, inflammation; Lipocalin 2; Lysosomes; Retinal pigment epithelium

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; ACUTE PHASE PROTEIN; CRYBA1 PROTEIN, MOUSE; CRYSTALLIN; LCN2 PROTEIN, MOUSE; LIPOCALIN; ONCOPROTEIN;

AGE RELATED MACULAR DEGENERATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; CRYBA1 GENE; GENE; GENETIC TRANSCRIPTION; GLIOSIS; HOMEOSTASIS; IMMUNOREACTIVITY; INNATE IMMUNITY; LYSOSOME; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN MOTIF; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; AGE; ANIMAL; CHRONIC DISEASE; DISEASE MODEL; GENETICS; INFLAMMATION; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; RETINAL PIGMENT EPITHELIUM;

MUS;

ACUTE-PHASE PROTEINS; AGE FACTORS; ANIMALS; CHRONIC DISEASE; CRYSTALLINS; DISEASE MODELS, ANIMAL; INFLAMMATION; LIPOCALINS; MACULAR DEGENERATION; MICE; ONCOGENE PROTEINS; RETINAL PIGMENT EPITHELIUM;

EID: 84911406431     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12274     Document Type: Article

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