Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress

Journal of Cellular and Molecular Medicine

Volumn 18, Issue 11, 2014, Pages 2298-2310

  Wang, Xue Qing ^a,b   Shao, Yong ^a,b   Ma, Chong Yi ^a,b   Chen, Wei ^a,b   Sun, Lu ^a,b   Liu, Wei ^b   Zhang, Dong Yang ^a,b   Fu, Bi Cheng ^a,b   Liu, Kai Yu ^a,b   Jia, Zhi Bo ^a,b   Xie, Bao Dong ^a,b   Jiang, Shu Lin ^a,b   Li, Ren Ke ^c   Tian, Hai ^a,b  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Ageing; Antioxidants; Mesenchymal stromal stem cells; Myocardium; Oxidative stress; SIRT3

Indexed keywords

ANTIOXIDANT; CATALASE; REACTIVE OXYGEN METABOLITE; SIRT3 PROTEIN, HUMAN; SIRTUIN 3; SUPEROXIDE DISMUTASE;

AGING; APOPTOSIS; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; OXIDATIVE STRESS; PATHOLOGY;

AGING; ANTIOXIDANTS; APOPTOSIS; CATALASE; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIRTUIN 3; SUPEROXIDE DISMUTASE;

EID: 84911051649     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12395     Document Type: Article

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