Long-Term Stability of a Vaccine Formulated with the Amphipol-Trapped Major Outer Membrane Protein from Chlamydia trachomatis

Journal of Membrane Biology

Volumn 247, Issue 9-10, 2014, Pages 1053-1065

  Eric Feinstein, H ^a   Tifrea, Delia ^a   Sun, Guifeng ^a   Popot, Jean Luc ^b   de la Maza, Luis M ^a   Cocco, Melanie J ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CNRS   (France)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amphipols; Chlamydia trachomatis; MOMP; NMR; Stability; Vaccine

Indexed keywords

BACTERIAL VACCINE; MAJOR OUTER MEMBRANE PROTEIN AMPHIPOL VACCINE; UNCLASSIFIED DRUG; DRUG CARRIER; OMPA OUTER MEMBRANE PROTEINS; OUTER MEMBRANE PROTEIN; SURFACTANT;

ARTICLE; CHLAMYDIA TRACHOMATIS; CIRCULAR DICHROISM; DENATURATION; DRUG FORMULATION; DRUG STABILITY; FREEZE THAWING; HEATING; IMMUNOCHEMISTRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; ROOM TEMPERATURE; SHELF LIFE; ULTRAVIOLET SPECTROSCOPY; CHEMICAL PHENOMENA; CHEMISTRY; DRUG SCREENING; MEDICINAL CHEMISTRY; PROTEIN CONFORMATION; PROTEIN DENATURATION; SOLUBILITY;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; CHEMISTRY, PHARMACEUTICAL; CHLAMYDIA TRACHOMATIS; DRUG CARRIERS; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; PROTEIN CONFORMATION; PROTEIN DENATURATION; SOLUBILITY; SURFACE-ACTIVE AGENTS;

EID: 84911004807     PISSN: 00222631     EISSN: 14321424     Source Type: Journal    
DOI: 10.1007/s00232-014-9693-5     Document Type: Article

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