Enterovirus-71 virus-like particles induce the activation and maturation of human monocyte-derived dendritic cells through TLR4 signaling

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Lin, Yu Li ^a   Hu, Yu Chen ^b   Liang, Cheng Chao ^c   Lin, Shih Yeh ^b   Liang, Yu Chih ^d   Yuan, Hui Ping ^a   Chiang, Bor Luen ^a,e  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; TOLL LIKE RECEPTOR 4; CYTOKINE; I KAPPA B; NF-KAPPAB INHIBITOR ALPHA; TLR4 PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVATION; CELL MATURATION; CELL SURFACE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENDOCYTOSIS; ENTEROVIRUS 71; HUMAN; HUMAN CELL; IMMUNOMODULATION; MONOCYTE; MONOCYTE DERIVED DENDRITIC CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH1 CELL; VIRUS ATTACHMENT; VIRUS LIKE AGENT; VIRUS NEUTRALIZATION; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; ENTEROVIRUS A; IMMUNOLOGY; METABOLISM; VIRION;

HUMAN ENTEROVIRUS 71;

CELL DIFFERENTIATION; CYTOKINES; DENDRITIC CELLS; ENDOCYTOSIS; ENTEROVIRUS A, HUMAN; HUMANS; I-KAPPA B PROTEINS; IMMUNOMODULATION; MODELS, BIOLOGICAL; MONOCYTES; NF-KAPPA B; PROTEOLYSIS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 4; VIRION;

EID: 84910148849     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111496     Document Type: Article

References (49)

1. Tagaya I, Takayama R, Hagiwara A (1981) A large-scale epidemic of hand, foot and mouth disease associated with enterovirus 71 infection in Japan in 1978. Jpn J Med Sci Biol 34: 191-196.
2. Wang SM, Lei HY, Yu CK, Wang JR, Su IJ, et al. (2008) Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis 198: 1002-1006.
3. Wu WH, Kuo TC, Lin YT, Huang SW, Liu HF, et al. (2013) Molecular epidemiology of enterovirus 71 infection in the central region of Taiwan from 2002 to 2012. PLoS One 8: e83711.
4. Wu CN, Lin YC, Fann C, Liao NS, Shih SR, et al. (2001) Protection against lethal enterovirus 71 infection in newborn mice by passive immunization with subunit VP1 vaccines and inactivated virus. Vaccine 20: 895-904.
5. McMinn PC (2002) An overview of the evolution of enterovirus 71 and its clinical and public health significance. FEMS Microbiol Rev 26: 91-107.
6. Zeltins A (2013) Construction and characterization of virus-like particles: a review. Mol Biotechnol 53: 92-107.
7. Vacher G, Kaeser MD, Moser C, Gurny R, Borchard G (2013) Recent advances in mucosal immunization using virus-like particles. Mol Pharm 10: 1596-1609.
8. Grgacic EV, Anderson DA (2006) Virus-like particles: passport to immune recognition. Methods 40: 60-65.
9. Hu YC, Hsu JT, Huang JH, Ho MS, Ho YC (2003) Formation of enterovirus-like particle aggregates by recombinant baculoviruses co-expressing P1 and 3CD in insect cells. Biotechnol Lett 25: 919-925.
10. Chung YC, Huang JH, Lai CW, Sheng HC, Shih SR, et al. (2006) Expression, purification and characterization of enterovirus-71 virus-like particles. World J - Gastroenterol 12: 921-927.
11. Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392: 245-252.
12. Cella M, Sallusto F, Lanzavecchia A (1997) Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 9: 10-16.
13. Aerts-Toegaert C, Heirman C, Tuyaerts S, Corthals J, Aerts JL, et al. (2007) CD83 expression on dendritic cells and T cells: correlation with effective immune responses. Eur J Immunol 37: 686-695.
14. Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20: 709-760.
15. Korokhov N, Noureddini SC, Curiel DT, Santegoets SJ, Scheper RJ, et al. (2005) A single-component CD40-targeted adenovirus vector displays highly efficient transduction and activation of dendritic cells in a human skin substrate system. Mol Pharm 2: 218-223.
16. Ausiello CM, Fedele G, Urbani F, Lande R, Di Carlo B, et al. (2002) Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses. J Infect Dis 186: 351-360.
17. Lin YL, Yu CI, Hu YC, Tsai TJ, Kuo YC, et al. (2012) Enterovirus type 71 neutralizing antibodies in the serum of macaque monkeys immunized with EV71 virus-like particles. Vaccine 30: 1305-1312.
18. Lin YL, Liang YC, Tseng YS, Huang HY, Chou SY, et al. (2009) An immunomodulatory protein, Ling Zhi-8, induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and MAPK pathways. J Leukoc Biol 86: 877-889.
19. Lin YW, Wang SW, Tung YY, Chen SH (2009) Enterovirus 71 infection of human dendritic cells. Exp Biol Med (Maywood) 234: 1166-1173.
20. Kato M, Neil TK, Fearnley DB, McLellan AD, Vuckovic S, et al. (2000) Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells. Int Immunol 12: 1511-1519.
21. Chou NT, Cheng CF, Wu HC, Lai CP, Lin LT, et al. (2012) Chlorella sorokiniana-Induced Activation and Maturation of Human Monocyte-Derived Dendritic Cells through NF-kappa B and PI3K/MAPK Pathways. Evidence-Based Complementary and Alternative Medicine.
22. Petsch D, Deckwer WD, Anspach FB (1998) Proteinase K digestion of proteins improves detection of bacterial endotoxins by the Limulus amebocyte lysate assay: application for endotoxin removal from cationic proteins. Anal Biochem 259: 42-47.
23. Ghosh S, May MJ, Kopp EB (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 16: 225-260.
24. Ramqvist T, Andreasson K, Dalianis T (2007) Vaccination, immune and gene therapy based on virus-like particles against viral infections and cancer. Expert Opin Biol Ther 7: 997-1007.
25. Szarewski A (2010) HPV vaccine: Cervarix. Expert Opin Biol Ther 10: 477-487.
26. Buonaguro FM, Tornesello ML, Buonaguro L (2009) Virus-like particle vaccines and adjuvants: the HPV paradigm. Expert Rev Vaccines 8: 1379-1398.
27. Young KR, McBurney SP, Karkhanis LU, Ross TM (2006) Virus-like particles: designing an effective AIDS vaccine. Methods 40: 98-117.
28. Shi L, Sings HL, Bryan JT, Wang B, Wang Y, et al. (2007) GARDASIL: prophylactic human papillomavirus vaccine development-from bench top to bed-side. Clin Pharmacol Ther 81: 259-264.
29. Chung YC, Ho MS, Wu JC, Chen WJ, Huang JH, et al. (2008) Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challenge. Vaccine 26: 1855-1862.
30. Trinchieri G (1993) Interleukin-12 and its role in the generation of TH1 cells. Immunol Today 14: 335-338.
31. Fayette J, Durand I, Bridon JM, Arpin C, Dubois B, et al. (1998) Dendritic cells enhance the differentiation of naive B cells into plasma cells in vitro. Scand J Immunol 48: 563-570.
32. Chen JG, Tong J, Liu HB, Liu YZ, Su ZL, et al. (2012) Increased frequency of Th17 cells in the peripheral blood of children infected with enterovirus 71. Journal of Medical Virology 84: 763-767.
33. MacDonald KPA, Munster DJ, Clark GJ, Dzionek A, Schmitz J, et al. (2002) Characterization of human blood dendritic cell subsets. Blood 100: 4512-4520.
34. Schreibelt G, Tel J, Sliepen KHEWJ, Benitez-Ribas D, Figdor CG, et al. (2010) Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer Immunology Immunotherapy 59: 1573-1582.
35. Schulte BM, Kers-Rebel ED, Prosser AC, Galama JMD, van Kuppeveld FJM, et al. (2013) Differential Susceptibility and Response of Primary Human Myeloid BDCA1(+) Dendritic Cells to Infection with Different Enteroviruses. Plos One 8.
36. Lenz P, Day PM, Pang YY, Frye SA, Jensen PN, et al. (2001) Papillomavirus-like particles induce acute activation of dendritic cells. J Immunol 166: 5346-5355.
37. Yan M, Peng J, Jabbar IA, Liu X, Filgueira L, et al. (2005) Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-kappaB-mediated signalling, moderated by TGF-beta. Immunol Cell Biol 83: 83-91.
38. Da Silva DM, Fausch SC, Verbeek JS, Kast WM (2007) Uptake of human papillomavirus virus-like particles by dendritic cells is mediated by Fcgamma receptors and contributes to acquisition of T cell immunity. J Immunol 178: 7587-7597.
39. Coll RC, O'Neill LA (2010) New insights into the regulation of signalling by toll-like receptors and nod-like receptors. J Innate Immun 2: 406-421.
40. Duenas AI, Orduna A, Crespo MS, Garcia-Rodriguez C (2004) Interaction of endotoxins with Toll-like receptor 4 correlates with their endotoxic potential and may explain the proinflammatory effect of Brucella spp. LPS. Int Immunol 16:1467-1475.
41. Yang H, Young DW, Gusovsky F, Chow JC (2000) Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1. J Biol Chem 275: 20861-20866.
42. Park BS, Song DH, Kim HM, Choi BS, Lee H, et al. (2009) The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 458: 1191-1195.
43. Plevka P, Perera R, Cardosa J, Kuhn RJ, Rossmann MG (2012) Crystal structure of human enterovirus 71. Science 336: 1274.
44. Ren XX, Ma L, Liu QW, Li C, Huang Z, et al. (2014) The molecule of DCSIGN captures enterovirus 71 and confers dendritic cell-mediated viral transinfection. Virology Journal 11.
45. Nishimura Y, Shimojima M, Tano Y, Miyamura T, Wakita T, et al. (2009) Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71. Nat Med 15: 794-797.
46. Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, et al. (2009) Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nat Med 15: 798-801.
47. Yamayoshi S, Koike S (2011) Identification of a human SCARB2 region that is important for enterovirus 71 binding and infection. J Virol 85: 4937-4946.
48. Yamayoshi S, Ohka S, Fujii K, Koike S (2013) Functional Comparison of SCARB2 and PSGL1 as Receptors for Enterovirus 71. Journal of Virology 87: 3335-3347.
49. Yoshimoto T, Kojima K, Funakoshi T, Endo Y, Fujita T, et al. (1996) Molecular cloning and characterization of murine IL-12 genes. J Immunol 156: 1082-1088.