Increased frequency of Th17 cells in the peripheral blood of children infected with enterovirus 71

Journal of Medical Virology

Volumn 84, Issue 5, 2012, Pages 763-767

  Chen, Jianguo ^a,b   Tong, Jia ^a,b   Liu, Haibing ^a,b   Liu, Yingzhao ^a,b   Su, Zhaoliang ^b   Wang, Shengjun ^a,b   Shi, Yan ^b   Zheng, Dong ^b   Sandoghchian, Siamak ^b   Geng, Jianzhong ^a   Xu, Huaxi ^b  

^a AFFILIATED PEOPLE S HOSPITAL OF JIANGSU UNIVERSITY   (China)

^b JIANGSU UNIVERSITY   (China)

Author keywords

Enterovirus 71; IL 17; IL 23; Neutrophil; ROR t; Th17

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 23; ORPHAN NUCLEAR RECEPTOR; ORPHAN NUCLEAR RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ARTICLE; BLOOD; BLOOD ANALYSIS; BLOOD CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; NEUTROPHIL; NEUTROPHIL COUNT; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TH17 CELL;

CHILD; CHILD, PRESCHOOL; CYTOKINES; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-23; NEUTROPHILS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, HELPER-INDUCER; TH17 CELLS;

HUMAN ENTEROVIRUS 71;

EID: 84863338910     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.23254     Document Type: Article

References (21)

1. Campillo-Gimenez L, Cumont MC, Fay M, Kared H, Monceaux V, Diop O, Muller-Trutwin M, Hurtrel B, Levy Y, Zaunders J, Dy M, Leite-de-Moraes MC, Elbim C, Estaquier J. 2010. AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection. J Immunol 184: 984- 992.
2. Cohen J. 2002. The immunopathogenesis of sepsis. Nature 420: 885- 891.
3. Ge J, Wang K, Meng QH, Qi ZX, Meng FL, Fan YC. 2010. Implication of Th17 and Th1 cells in patients with chronic active hepatitis B. J Clin Immunol 30: 60- 67.
4. Hashimoto K, Durbin JE, Zhou W, Collins RD, Ho SB, Kolls JK, Dubin PJ, Sheller JR, Goleniewska K, O'Neal JF, Olson SJ, Mitchell D, Graham BS, Peebles RS Jr. 2005. Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels. J Allergy Clin Immunol 116: 550- 557.
5. Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK. 2010. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett 127: 150- 156.
6. Higgins SC, Jarnicki AG, Lavelle EC, Mills KH. 2006. TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: Role of IL-17-producing T cells. J Immunol 177: 7980- 7989.
7. Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. 2006. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121- 1133.
8. Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J, Cilley GE, Shen F, Eaton SM, Gaffen SL, Swain SL, Locksley RM, Haynes L, Randall TD, Cooper AM. 2007. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 8: 369- 377.
9. Li X, Yuan FL, Lu WG, Zhao YQ, Li CW, Li JP, Xu RS. 2010. The role of interleukin-17 in mediating joint destruction in rheumatoid arthritis. Biochem Biophys Res Commun 397: 131- 135.
10. Luger D, Silver PB, Tang J, Cua D, Chen Z, Iwakura Y, Bowman EP, Sgambellone NM, Chan CC, Caspi RR. 2008. Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category. J Exp Med 205: 799- 810.
11. Maek ANW, Buranapraditkun S, Klaewsongkram J, Ruxrungtham K. 2007. Increased interleukin-17 production both in helper T cell subset Th17 and CD4-negative T cells in human immunodeficiency virus infection. Viral Immunol 20: 66- 75.
12. Mao LX, Wu B, Bao WX, Han FA, Xu L, Ge QJ, Yang J, Yuan ZH, Miao CH, Huang XX, Zhang C, Xu H. 2010. Epidemiology of hand, foot, and mouth disease and genotype characterization of Enterovirus 71 in Jiangsu, China. J Clin Virol 49: 100- 104.
13. McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ. 2007. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol 8: 1390- 1397.
14. Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A. 2003. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways. J Immunol 170: 4665- 4672.
15. Mollers M, Aries SP, Dromann D, Mascher B, Braun J, Dalhoff K. 2001. Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis. Thorax 56: 487- 493.
16. Rowan AG, Fletcher JM, Ryan EJ, Moran B, Hegarty JE, O'Farrelly C, Mills KH. 2008. Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta. J Immunol 181: 4485- 4494.
17. Shi Y, Wang H, Su Z, Chen J, Xue Y, Wang S, He Z, Yang H, Zhou C, Kong F, Liu Y, Yang P, Lu L, Shao Q, Huang X, Xu H. 2010. Differentiation imbalance of Th1/Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimoto's thyroiditis. Scand J Immunol 72: 250- 255.
18. Wu C, Wang S, Wang F, Chen Q, Peng S, Zhang Y, Qian J, Jin J, Xu H. 2009. Increased frequencies of T helper type 17 cells in the peripheral blood of patients with acute myeloid leukaemia. Clin Exp Immunol 158: 199- 204.
19. Wu Q, Martin RJ, Rino JG, Breed R, Torres RM, Chu HW. 2007. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes Infect 9: 78- 86.
20. Yang F, Ren L, Xiong Z, Li J, Xiao Y, Zhao R, He Y, Bu G, Zhou S, Wang J, Qi J. 2009. Enterovirus 71 outbreak in the People's Republic of China in 2008. J Clin Microbiol 47: 2351- 2352.
21. Ye P, Garvey PB, Zhang P, Nelson S, Bagby G, Summer WR, Schwarzenberger P, Shellito JE, Kolls JK. 2001. Interleukin-17 and lung host defense against Klebsiella pneumoniae infection. Am J Respir Cell Mol Biol 25: 335- 340.