Lyn deficiency leads to increased microbiota-Dependent intestinal inflammation and susceptibility to enteric pathogens

Journal of Immunology

Volumn 193, Issue 10, 2014, Pages 5249-5263

  Roberts, Morgan E ^a   Bishop, Jennifer L ^a   Fan, Xueling ^a   Beer, Jennifer L ^a   Kum, Winnie W S ^a,b   Krebs, Danielle L ^a   Huang, Morris ^a   Gill, Navkiran ^a,b   Priatel, John J ^c   Finlay, B Brett ^a,b   Harder, Kenneth W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN A; INTERLEUKIN 17; INTERLEUKIN 22; PROTEIN KINASE LYN; DEXTRAN SULFATE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL TRANSMISSION; CELL EXPANSION; CITROBACTER RODENTIUM; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; DYSBIOSIS; EMBRYO; FEMALE; GASTROENTERITIS; IMMUNE RESPONSE; IMMUNE SYSTEM; INTESTINE FLORA; INTESTINE INFECTION; MALE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN FUNCTION; RECTUM HEMORRHAGE; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; T LYMPHOCYTE; UPREGULATION; ANIMAL; B LYMPHOCYTE; CHEMICALLY INDUCED; DEFICIENCY; ENTEROBACTERIACEAE INFECTION; GENE EXPRESSION; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; MICROFLORA; PATHOGENICITY; PATHOLOGY; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SEVERITY OF ILLNESS INDEX;

ANIMALS; B-LYMPHOCYTES; CITROBACTER RODENTIUM; COLITIS; DEXTRAN SULFATE; DISEASE SUSCEPTIBILITY; DYSBIOSIS; ENTEROBACTERIACEAE INFECTIONS; FEMALE; GENE EXPRESSION; IMMUNOGLOBULIN A; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKINS; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT; MICROBIOTA; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; SEVERITY OF ILLNESS INDEX; SRC-FAMILY KINASES; T-LYMPHOCYTES;

EID: 84910115605     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302832     Document Type: Article

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