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Volumn 15, Issue 11, 2014, Pages 20306-20320

Post-transcriptional up-regulation of PDGF-C by HuR in advanced and stressed breast cancer

Author keywords

Breast neoplasms; HuR; MRNA stability; Platelet derived growth factor C (PDGF C)

Indexed keywords

HUR PROTEIN; PLATELET DERIVED GROWTH FACTOR C; 3' UNTRANSLATED REGION; ELAV PROTEIN; LYMPHOKINE; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR C;

EID: 84910107534     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms151120306     Document Type: Article
Times cited : (15)

References (36)
  • 1
    • 77955942384 scopus 로고    scopus 로고
    • Functional proteomics to dissect tyrosine kinase signalling pathways in cancer
    • Kolch, W.; Pitt, A. Functional proteomics to dissect tyrosine kinase signalling pathways in cancer. Nat. Rev. Cancer 2010, 10, 618-629.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 618-629
    • Kolch, W.1    Pitt, A.2
  • 2
    • 84887104840 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor 2 (HER2)-positive and hormone receptor-positive breast cancer: New insights into molecular interactions and clinical implications
    • Montemurro, F.; di Cosimo, S.; Arpino, G. Human epidermal growth factor receptor 2 (HER2)-positive and hormone receptor-positive breast cancer: New insights into molecular interactions and clinical implications. Ann. Oncol. 2013, 24, 2715-2724.
    • (2013) Ann. Oncol , vol.24 , pp. 2715-2724
    • Montemurro, F.1    Di Cosimo, S.2    Arpino, G.3
  • 3
    • 84862933330 scopus 로고    scopus 로고
    • Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: Implications for breast cancer
    • Hurst, N.J.; Najy, A.J.; Ustach, C.V.; Movilla, L.; Kim, H.R. Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: Implications for breast cancer progression. Biochem. J. 2012, 441, 909-918.
    • (2012) Progression. Biochem. J , vol.441 , pp. 909-918
    • Hurst, N.J.1    Najy, A.J.2    Ustach, C.V.3    Movilla, L.4    Kim, H.R.5
  • 4
    • 28044473866 scopus 로고    scopus 로고
    • Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family
    • Reigstad, L.J.; Varhaug, J.E.; Lillehaug, J.R. Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family. FEBS J. 2005, 272, 5723-5741.
    • (2005) FEBS J , vol.272 , pp. 5723-5741
    • Reigstad, L.J.1    Varhaug, J.E.2    Lillehaug, J.R.3
  • 5
    • 33847355253 scopus 로고    scopus 로고
    • The platelet-derived growth factor receptor as a therapeutic target
    • Lewis, N.L. The platelet-derived growth factor receptor as a therapeutic target. Curr. Oncol. Rep. 2007, 9, 89-95.
    • (2007) Curr. Oncol. Rep , vol.9 , pp. 89-95
    • Lewis, N.L.1
  • 6
    • 0038544202 scopus 로고    scopus 로고
    • Platelet-derived growth factor signaling and human cancer
    • Yu, J.; Ustach, C.; Kim, H.R. Platelet-derived growth factor signaling and human cancer. J. Biochem. Mol. Biol. 2003, 36, 49-59.
    • (2003) J. Biochem. Mol. Biol , vol.36 , pp. 49-59
    • Yu, J.1    Ustach, C.2    Kim, H.R.3
  • 8
    • 84896867662 scopus 로고    scopus 로고
    • Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt and Bad phosphorylation
    • Son, D.; Na, Y.R.; Hwang, E.S.; Seok, S.H. Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt and Bad phosphorylation. J. Biol. Chem. 2014, 289, 6225-6235.
    • (2014) J. Biol. Chem , vol.289 , pp. 6225-6235
    • Son, D.1    Na, Y.R.2    Hwang, E.S.3    Seok, S.H.4
  • 10
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • Fabian, M.R.; Sonenberg, N.; Filipowicz, W. Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 2010, 79, 351-379.
    • (2010) Annu. Rev. Biochem , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 11
    • 84889879702 scopus 로고    scopus 로고
    • Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition
    • Aparicio, L.A.; Abella, V.; Valladares, M.; Figueroa, A. Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition. Cell. Mol. Life Sci. 2013, 70, 4463-4477.
    • (2013) Cell. Mol. Life Sci , vol.70 , pp. 4463-4477
    • Aparicio, L.A.1    Abella, V.2    Valladares, M.3    Figueroa, A.4
  • 12
    • 79952759375 scopus 로고    scopus 로고
    • Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip
    • Abdelmohsen, K.; Gorospe, M. Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip. Rev. RNA 2010, 1, 214-229.
    • (2010) Rev. RNA , vol.1 , pp. 214-229
    • Abdelmohsen, K.1    Gorospe, M.2
  • 13
    • 0029873536 scopus 로고    scopus 로고
    • Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
    • Ma, W.J.; Cheng, S.; Campbell, C.; Wright, A.; Furneaux, H. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J. Biol. Chem. 1996, 271, 8144-8151.
    • (1996) J. Biol. Chem , vol.271 , pp. 8144-8151
    • Ma, W.J.1    Cheng, S.2    Campbell, C.3    Wright, A.4    Furneaux, H.5
  • 14
    • 0032526427 scopus 로고    scopus 로고
    • Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
    • Fan, X.C.; Steitz, J.A. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 1998, 17, 3448-3460.
    • (1998) EMBO J , vol.17 , pp. 3448-3460
    • Fan, X.C.1    Steitz, J.A.2
  • 15
    • 0035976612 scopus 로고    scopus 로고
    • Delineation of mRNA export pathways by the use of cell-permeable peptides
    • Gallouzi, I.E.; Steitz, J.A. Delineation of mRNA export pathways by the use of cell-permeable peptides. Science 2001, 294, 1895-1901.
    • (2001) Science , vol.294 , pp. 1895-1901
    • Gallouzi, I.E.1    Steitz, J.A.2
  • 16
    • 0035030368 scopus 로고    scopus 로고
    • Breast cancer genetics: What we know and what we need
    • Nathanson, K.L.; Wooster, R.; Weber, B.L. Breast cancer genetics: What we know and what we need. Nat. Med. 2001, 7, 552-556.
    • (2001) Nat. Med , vol.7 , pp. 552-556
    • Nathanson, K.L.1    Wooster, R.2    Weber, B.L.3
  • 17
    • 84902297754 scopus 로고    scopus 로고
    • Adaptive and maladaptive expression of the mRNA regulatory protein HuR. World
    • Govindaraju, S.; Lee, B.S. Adaptive and maladaptive expression of the mRNA regulatory protein HuR. World J. Biol. Chem. 2013, 4, 111-118.
    • (2013) J. Biol. Chem , vol.4 , pp. 111-118
    • Govindaraju, S.1    Lee, B.S.2
  • 18
    • 57349135602 scopus 로고    scopus 로고
    • Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: The potential involvement of the RNA-binding protein HuR
    • Amadio, M.; Scapagnini, G.; Laforenza, U.; Intrieri, M.; Romeo, L.; Govoni, S.; Pascale, A. Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: The potential involvement of the RNA-binding protein HuR. Curr. Pharm. Des. 2008, 14, 2651-2658.
    • (2008) Curr. Pharm. Des , vol.14 , pp. 2651-2658
    • Amadio, M.1    Scapagnini, G.2    Laforenza, U.3    Intrieri, M.4    Romeo, L.5    Govoni, S.6    Pascale, A.7
  • 20
    • 73249130836 scopus 로고    scopus 로고
    • Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas
    • Bruland, O.; Fluge, O.; Akslen, L.A.; Eiken, H.G.; Lillehaug, J.R.; Varhaug, J.E.; Knappskog, P.M. Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas. BMC Cancer 2009, 9, 425.
    • (2009) BMC Cancer , vol.9 , pp. 425
    • Bruland, O.1    Fluge, O.2    Akslen, L.A.3    Eiken, H.G.4    Lillehaug, J.R.5    Varhaug, J.E.6    Knappskog, P.M.7
  • 24
    • 0034657686 scopus 로고    scopus 로고
    • HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation
    • Wang, W.; Caldwell, M.C.; Lin, S.; Furneaux, H.; Gorospe, M. HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. EMBO J. 2000, 19, 2340-2350.
    • (2000) EMBO J , vol.19 , pp. 2340-2350
    • Wang, W.1    Caldwell, M.C.2    Lin, S.3    Furneaux, H.4    Gorospe, M.5
  • 25
    • 65449184997 scopus 로고    scopus 로고
    • The expression of RNA-binding protein HuR in non-small cell lung cancer correlates with vascular endothelial growth factor-C expression and lymph node metastasis
    • Wang, J.; Zhao, W.; Guo, Y.; Zhang, B.; Xie, Q.; Xiang, D.; Gao, J.; Wang, B.; Chen, Z. The expression of RNA-binding protein HuR in non-small cell lung cancer correlates with vascular endothelial growth factor-C expression and lymph node metastasis. Oncol. Basel 2009, 76, 420-429.
    • (2009) Oncol. Basel , vol.76 , pp. 420-429
    • Wang, J.1    Zhao, W.2    Guo, Y.3    Zhang, B.4    Xie, Q.5    Xiang, D.6    Gao, J.7    Wang, B.8    Chen, Z.9
  • 26
    • 84876154977 scopus 로고    scopus 로고
    • MiR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer
    • Al-Ahmadi, W.; Al-Ghamdi, M.; Al-Souhibani, N.; Khabar, K.S. miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer. J. Pathol. 2013, 230, 28-38.
    • (2013) J. Pathol , vol.230 , pp. 28-38
    • Al-Ahmadi, W.1    Al-Ghamdi, M.2    Al-Souhibani, N.3    Khabar, K.S.4
  • 27
    • 79960157540 scopus 로고    scopus 로고
    • Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer
    • Wang, J.; Wang, B.; Bi, J.; Zhang, C. Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer. Med. Oncol. 2011, 28, S577-S585.
    • (2011) Med. Oncol , vol.28 , pp. S577-S585
    • Wang, J.1    Wang, B.2    Bi, J.3    Zhang, C.4
  • 28
    • 84881480646 scopus 로고    scopus 로고
    • Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer
    • Zhu, Z.; Wang, B.; Bi, J.; Zhang, C.; Guo, Y.; Chu, H.; Liang, X.; Zhong, C.; Wang, J. Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer. Tumor Biol. 2013, 34, 2299-2308.
    • (2013) Tumor Biol , vol.34 , pp. 2299-2308
    • Zhu, Z.1    Wang, B.2    Bi, J.3    Zhang, C.4    Guo, Y.5    Chu, H.6    Liang, X.7    Zhong, C.8    Wang, J.9
  • 29
    • 0031783046 scopus 로고    scopus 로고
    • Protein HuA (HuR) can redistribute between nucleus and cytoplasm and is up-regulated during serum stimulation and T cell activation
    • Atasoy, U.; Watson, J.; Patel, D.; Keene, J.D. ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is up-regulated during serum stimulation and T cell activation. J. Cell Sci. 1998, 111, 3145-3156.
    • (1998) J. Cell Sci , vol.111 , pp. 3145-3156
    • Atasoy, U.1    Watson, J.2    Patel, D.3    Keene, J.4
  • 32
    • 68949161769 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase-and HuR-dependent stabilization of p21Cip1 mRNA mediates the G1/S checkpoint
    • Lafarga, V.; Cuadrado, A.; Lopez, D.S.I.; Bengoechea, R.; Fernandez-Capetillo, O.; Nebreda, A.R. p38 Mitogen-activated protein kinase-and HuR-dependent stabilization of p21Cip1 mRNA mediates the G1/S checkpoint. Mol. Cell Biol. 2009, 29, 4341-4351.
    • (2009) Mol. Cell Biol , vol.29 , pp. 4341-4351
    • Lafarga, V.1    Cuadrado, A.2    Lopez, D.3    Bengoechea, R.4    Fernandez-Capetillo, O.5    Nebreda, A.R.6
  • 33
    • 84866358168 scopus 로고    scopus 로고
    • The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
    • Bouwman, P.; Jonkers, J. The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance. Nat. Rev. Cancer 2012, 12, 587-598.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 587-598
    • Bouwman, P.1    Jonkers, J.2
  • 36
    • 4644362064 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1
    • Midgley, V.C.; Khachigian, L.M. Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1. J. Biol. Chem. 2004, 279, 40289-40295.
    • (2004) J. Biol. Chem , vol.279 , pp. 40289-40295
    • Midgley, V.C.1    Khachigian, L.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.