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Volumn 441, Issue 3, 2012, Pages 909-918

Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: Implications for breast cancer progression

Author keywords

Breast cancer; Hemidimer; Platelet derived growth factor C (PDGF C); Proteolytic processing; Serine protease

Indexed keywords

GROWTH FACTOR; MATRIPTASE; PLATELET DERIVED GROWTH FACTOR C; SERINE PROTEINASE; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

EID: 84862933330     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111020     Document Type: Article
Times cited : (44)

References (53)
  • 1
    • 0023505080 scopus 로고
    • Polypeptide growth factors: Roles in normal and abnormal cell growth
    • Deuel, T. F. (1987) Polypeptide growth factors: roles in normal and abnormal cell growth. Annu. Rev. Cell Biol. 3, 443-492
    • (1987) Annu. Rev. Cell Biol. , vol.3 , pp. 443-492
    • Deuel, T.F.1
  • 2
    • 0022457822 scopus 로고
    • The biology of platelet-derived growth factor
    • Ross, R., Raines, E. W. and Bowen-Pope, D. F. (1986) The biology of platelet-derived growth factor. Cell 46, 155-169 (Pubitemid 16031684)
    • (1986) Cell , vol.46 , Issue.2 , pp. 155-169
    • Ross, R.1    Raines, E.W.2    Bowen-Pope, D.F.3
  • 3
    • 0032462002 scopus 로고    scopus 로고
    • Evidence for distinct signaling properties and biological responses induced by the PDGF receptor α and β subtypes
    • Rosenkranz, S. and Kazlauskas, A. (1999) Evidence for distinct signaling properties and biological responses induced by the PDGF receptor α and β subtypes. Growth Factors 16, 201-216 (Pubitemid 129725725)
    • (1999) Growth Factors , vol.16 , Issue.3 , pp. 201-216
    • Rosenkranz, S.1    Kazlauskas, A.2
  • 4
    • 58249095931 scopus 로고    scopus 로고
    • Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts
    • Anderberg, C., Li, H., Fredriksson, L., Andrae, J., Betsholtz, C., Li, X., Eriksson, U. and Pietras, K. (2009) Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res. 69, 369-378
    • (2009) Cancer Res. , vol.69 , pp. 369-378
    • Anderberg, C.1    Li, H.2    Fredriksson, L.3    Andrae, J.4    Betsholtz, C.5    Li, X.6    Eriksson, U.7    Pietras, K.8
  • 5
    • 57849106330 scopus 로고    scopus 로고
    • PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
    • Crawford, Y., Kasman, I., Yu, L., Zhong, C., Wu, X., Modrusan, Z., Kaminker, J. and Ferrara, N. (2009) PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 15, 21-34
    • (2009) Cancer Cell , vol.15 , pp. 21-34
    • Crawford, Y.1    Kasman, I.2    Yu, L.3    Zhong, C.4    Wu, X.5    Modrusan, Z.6    Kaminker, J.7    Ferrara, N.8
  • 6
    • 0029039982 scopus 로고
    • Expression of plateletderived growth factor B-chain and the platelet-derived growth factor receptor β subunit in human breast tissue and breast carcinoma
    • Coltrera, M. D., Wang, J., Porter, P. L. and Gown, A. M. (1995) Expression of plateletderived growth factor B-chain and the platelet-derived growth factor receptor β subunit in human breast tissue and breast carcinoma. Cancer Res. 55, 2703-2708
    • (1995) Cancer Res. , vol.55 , pp. 2703-2708
    • Coltrera, M.D.1    Wang, J.2    Porter, P.L.3    Gown, A.M.4
  • 7
    • 33644873490 scopus 로고    scopus 로고
    • Overexpression of platelet-derived growth factor receptor α in breast cancer is associated with tumour progression
    • Carvalho, I., Milanezi, F., Martins, A., Reis, R. M. and Schmitt, F. (2005) Overexpression of platelet-derived growth factor receptor α in breast cancer is associated with tumour progression. Breast Cancer Res. 7, R788-R795
    • (2005) Breast Cancer Res. , vol.7
    • Carvalho, I.1    Milanezi, F.2    Martins, A.3    Reis, R.M.4    Schmitt, F.5
  • 8
    • 0035032263 scopus 로고    scopus 로고
    • The complexities of breast cancer desmoplasia
    • Walker, R. A. (2001) The complexities of breast cancer desmoplasia. Breast Cancer Res. 3, 143-145
    • (2001) Breast Cancer Res. , vol.3 , pp. 143-145
    • Walker, R.A.1
  • 9
    • 0034618408 scopus 로고    scopus 로고
    • Human breast carcinoma desmoplasia is PDGF initiated
    • Shao, Z. M., Nguyen, M. and Barsky, S. H. (2000) Human breast carcinoma desmoplasia is PDGF initiated. Oncogene 19, 4337-4345
    • (2000) Oncogene , vol.19 , pp. 4337-4345
    • Shao, Z.M.1    Nguyen, M.2    Barsky, S.H.3
  • 11
    • 0035242001 scopus 로고    scopus 로고
    • PDGC-C is an EWS/FLI induced transforming growth factor in Ewing family tumors
    • DOI 10.1038/sj.onc.1204133
    • Zwerner, J. P. and May, W. A. (2001) PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors. Oncogene 20, 626-633 (Pubitemid 32156187)
    • (2001) Oncogene , vol.20 , Issue.5 , pp. 626-633
    • Zwerner, J.P.1    May, W.A.2
  • 12
    • 0037198637 scopus 로고    scopus 로고
    • Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines
    • DOI 10.1038/sj/onc/1205486
    • Zwerner, J. P. and May, W. A. (2002) Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines. Oncogene 21, 3847-3854 (Pubitemid 34620852)
    • (2002) Oncogene , vol.21 , Issue.24 , pp. 3847-3854
    • Zwerner, J.P.1    May, W.A.2
  • 13
    • 0036645057 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: Evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors
    • Lokker, N. A., Sullivan, C. M., Hollenbach, S. J., Israel, M. A. and Giese, N. A. (2002) Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors. Cancer Res. 62, 3729-3735 (Pubitemid 34728854)
    • (2002) Cancer Research , vol.62 , Issue.13 , pp. 3729-3735
    • Lokker, N.A.1    Sullivan, C.M.2    Hollenbach, S.J.3    Israel, M.A.4    Giese, N.A.5
  • 14
    • 0036385854 scopus 로고    scopus 로고
    • Platelet-derived growth factor-B and -C and active α-receptors in medulloblastoma cells
    • Andrae, J., Molander, C., Smits, A., Funa, K. and Nister, M. (2002) Platelet-derived growth factor-B and -C and active α-receptors in medulloblastoma cells. Biochem. Biophys. Res. Commun. 296, 604-611
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 604-611
    • Andrae, J.1    Molander, C.2    Smits, A.3    Funa, K.4    Nister, M.5
  • 18
    • 22844439785 scopus 로고    scopus 로고
    • Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator
    • DOI 10.1074/jbc.M503388200
    • Fredriksson, L., Ehnman, M., Fieber, C. and Eriksson, U. (2005) Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator. J. Biol. Chem. 280, 26856-26862 (Pubitemid 41040719)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.29 , pp. 26856-26862
    • Fredriksson, L.1    Ehnman, M.2    Fieber, C.3    Eriksson, U.4
  • 19
    • 0023373687 scopus 로고
    • Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes
    • Fuerst, T. R., Earl, P. L. and Moss, B. (1987) Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes. Mol. Cell. Biol. 7, 2538-2544
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2538-2544
    • Fuerst, T.R.1    Earl, P.L.2    Moss, B.3
  • 20
    • 6344236867 scopus 로고    scopus 로고
    • Tissue plasminogen activator is a potent activator of PDGF-CC
    • DOI 10.1038/sj.emboj.7600397
    • Fredriksson, L., Li, H., Fieber, C., Li, X. and Eriksson, U. (2004) Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J. 23, 3793-3802 (Pubitemid 39389710)
    • (2004) EMBO Journal , vol.23 , Issue.19 , pp. 3793-3802
    • Fredriksson, L.1    Li, H.2    Fieber, C.3    Li, X.4    Eriksson, U.5
  • 21
    • 39549100205 scopus 로고    scopus 로고
    • Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy
    • Lei, H., Velez, G., Hovland, P., Hirose, T. and Kazlauskas, A. (2008) Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Invest. Ophthalmol. Vis. Sci. 49, 42-48
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 42-48
    • Lei, H.1    Velez, G.2    Hovland, P.3    Hirose, T.4    Kazlauskas, A.5
  • 23
    • 0034714379 scopus 로고    scopus 로고
    • Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
    • Takeuchi, T., Harris, J. L., Huang, W., Yan, K. W., Coughlin, S. R. and Craik, C. S. (2000) Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates. J. Biol. Chem. 275, 26333-26342
    • (2000) J. Biol. Chem. , vol.275 , pp. 26333-26342
    • Takeuchi, T.1    Harris, J.L.2    Huang, W.3    Yan, K.W.4    Coughlin, S.R.5    Craik, C.S.6
  • 24
    • 21744439110 scopus 로고    scopus 로고
    • Platelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells
    • DOI 10.1128/MCB.25.14.6279-6288.2005
    • Ustach, C. V. and Kim, H. R. (2005) Platelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells. Mol. Cell. Biol. 25, 6279-6288 (Pubitemid 40946575)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.14 , pp. 6279-6288
    • Ustach, C.V.1    Kim, H.-R.C.2
  • 25
    • 0026331304 scopus 로고
    • Basic and clinical aspects of fibrinolysis and thrombolysis
    • Collen, D. and Lijnen, H. R. (1991) Basic and clinical aspects of fibrinolysis and thrombolysis. Blood 78, 3114-3124
    • (1991) Blood , vol.78 , pp. 3114-3124
    • Collen, D.1    Lijnen, H.R.2
  • 26
    • 0029665065 scopus 로고    scopus 로고
    • The 2.3 Å crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator
    • Lamba, D., Bauer, M., Huber, R., Fischer, S., Rudolph, R., Kohnert, U. and Bode, W. (1996) The 2.3 Å crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator. J. Mol. Biol. 258, 117-135
    • (1996) J. Mol. Biol. , vol.258 , pp. 117-135
    • Lamba, D.1    Bauer, M.2    Huber, R.3    Fischer, S.4    Rudolph, R.5    Kohnert, U.6    Bode, W.7
  • 28
    • 0036906177 scopus 로고    scopus 로고
    • uPAR: A versatile signalling orchestrator
    • DOI 10.1038/nrm977
    • Blasi, F. and Carmeliet, P. (2002) uPAR: a versatile signalling orchestrator. Nat. Rev. Mol. Cell Biol. 3, 932-943 (Pubitemid 35477371)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.12 , pp. 932-943
    • Blasi, F.1    Carmeliet, P.2
  • 29
    • 0030064016 scopus 로고    scopus 로고
    • Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator
    • DOI 10.1074/jbc.271.8.4461
    • Coombs, G. S., Dang, A. T., Madison, E. L. and Corey, D. R. (1996) Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator. J. Biol. Chem. 271, 4461-4467 (Pubitemid 26070555)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.8 , pp. 4461-4467
    • Coombs, G.S.1    Dang, A.T.2    Madison, E.L.3    Corey, D.R.4
  • 30
    • 0030997660 scopus 로고    scopus 로고
    • Distinguishing the specificities of closely related proteases: Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase
    • DOI 10.1074/jbc.272.26.16603
    • Ke, S. H., Coombs, G. S., Tachias, K., Navre, M., Corey, D. R. and Madison, E. L. (1997) Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase. J. Biol. Chem. 272, 16603-16609 (Pubitemid 27276491)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.26 , pp. 16603-16609
    • Ke, S.-H.1    Coombs, G.S.2    Tachias, K.3    Navre, M.4    Corey, D.R.5    Madison, E.L.6
  • 31
    • 0030878999 scopus 로고    scopus 로고
    • Optimal subsite occupancy and design of a selective inhibitor of urokinase
    • DOI 10.1074/jbc.272.33.20456
    • Ke, S. H., Coombs, G. S., Tachias, K., Corey, D. R. and Madison, E. L. (1997) Optimal subsite occupancy and design of a selective inhibitor of urokinase. J. Biol. Chem. 272, 20456-20462 (Pubitemid 27355599)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20456-20462
    • Ke, S.-H.1    Coombs, G.S.2    Tachias, K.3    Corey, D.R.4    Madison, E.L.5
  • 32
    • 0025972053 scopus 로고
    • Substrate specificity of tissue-type and urokinase-type plasminogen activators
    • Rijken, D. C. and Groeneveld, E. (1991) Substrate specificity of tissue-type and urokinase-type plasminogen activators. Biochem. Biophys. Res. Commun. 174, 432-438
    • (1991) Biochem. Biophys. Res. Commun. , vol.174 , pp. 432-438
    • Rijken, D.C.1    Groeneveld, E.2
  • 34
    • 0027474797 scopus 로고
    • Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells
    • Shi, Y. E., Torri, J., Yieh, L., Wellstein, A., Lippman, M. E. and Dickson, R. B. (1993) Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells. Cancer Res. 53, 1409-1415 (Pubitemid 23097125)
    • (1993) Cancer Research , vol.53 , Issue.6 , pp. 1409-1415
    • Shi, Y.E.1    Torri, J.2    Yieh, L.3    Wellstein, A.4    Lippman, M.E.5    Dickson, R.B.6
  • 35
    • 0033603574 scopus 로고    scopus 로고
    • Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity
    • Lin, C. Y., Anders, J., Johnson, M., Sang, Q. A. and Dickson, R. B. (1999) Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity. J. Biol. Chem. 274, 18231-18236
    • (1999) J. Biol. Chem. , vol.274 , pp. 18231-18236
    • Lin, C.Y.1    Anders, J.2    Johnson, M.3    Sang, Q.A.4    Dickson, R.B.5
  • 36
    • 0033613123 scopus 로고    scopus 로고
    • Reverse biochemistry: Use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue
    • DOI 10.1073/pnas.96.20.11054
    • Takeuchi, T., Shuman, M. A. and Craik, C. S. (1999) Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. Proc. Natl. Acad. Sci. U.S.A. 96, 11054-11061 (Pubitemid 29487326)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.20 , pp. 11054-11061
    • Takeuchi, T.1    Shuman, M.A.2    Craik, C.S.3
  • 37
    • 0032923230 scopus 로고    scopus 로고
    • Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains
    • DOI 10.1007/s002510050515
    • Kim, M. G., Chen, C., Lyu, M. S., Cho, E. G., Park, D., Kozak, C. and Schwartz, R. H. (1999) Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains. Immunogenetics 49, 420-428 (Pubitemid 29178825)
    • (1999) Immunogenetics , vol.49 , Issue.5 , pp. 420-428
    • Kim, M.G.1    Chen, C.2    Lyu, M.S.3    Cho, E.-G.4    Park, D.5    Kozak, C.6    Schwartz, R.H.7
  • 38
    • 33646514271 scopus 로고    scopus 로고
    • Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis
    • List, K., Szabo, R., Molinolo, A., Nielsen, B. S. and Bugge, T. H. (2006) Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis. Am. J. Pathol. 168, 1513-1525
    • (2006) Am. J. Pathol. , vol.168 , pp. 1513-1525
    • List, K.1    Szabo, R.2    Molinolo, A.3    Nielsen, B.S.4    Bugge, T.H.5
  • 40
    • 0035178571 scopus 로고    scopus 로고
    • Ovarian tumor cells express a transmembrane serine protease: A potential candidate for early diagnosis and therapeutic intervention
    • DOI 10.1159/000050604
    • Tanimoto, H., Underwood, L. J., Wang, Y., Shigemasa, K., Parmley, T. H. and O'Brien, T. J. (2001) Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention. Tumour Biol. 22, 104-114 (Pubitemid 32008967)
    • (2001) Tumor Biology , vol.22 , Issue.2 , pp. 104-114
    • Tanimoto, H.1    Underwood, L.J.2    Wang, Y.3    Shigemasa, K.4    Parmley, T.H.5    O'Brien, T.J.6
  • 41
    • 0034711244 scopus 로고    scopus 로고
    • Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease
    • DOI 10.1074/jbc.M007802200
    • Lee, S. L., Dickson, R. B. and Lin, C. Y. (2000) Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease. J. Biol. Chem. 275, 36720-36725 (Pubitemid 32002078)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.47 , pp. 36720-36725
    • Lee, S.-L.1    Dickson, R.B.2    Lin, C.-Y.3
  • 44
    • 30644459109 scopus 로고    scopus 로고
    • Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitr type 1 in normal and malignant tissues of gastrointestinal tract
    • Zeng, L., Cao, J. and Zhang, X. (2005) Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract. World J. Gastroenterol. 11, 6202-6207 (Pubitemid 43085066)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.39 , pp. 6202-6207
    • Zeng, L.1    Cao, J.2    Zhang, X.3
  • 45
    • 14844304649 scopus 로고    scopus 로고
    • Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): Expression and prognostic value in ovarian cancer
    • DOI 10.1038/sj.bjc.6602320
    • Tanimoto, H., Shigemasa, K., Tian, X., Gu, L., Beard, J. B., Sawasaki, T. and O'Brien, T. J. (2005) Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): expression and prognostic value in ovarian cancer. Br. J. Cancer 92, 278-283 (Pubitemid 40343141)
    • (2005) British Journal of Cancer , vol.92 , Issue.2 , pp. 278-283
    • Tanimoto, H.1    Shigemasa, K.2    Tian, X.3    Gu, L.4    Beard, J.B.5    Sawasaki, T.6    O'Brien, T.J.7
  • 46
    • 28344448867 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator is upregulated in metastatic breast cancer cells exposed to insulin-like growth factor-I
    • Chernicky, C. L., Yi, L., Tan, H. and Ilan, J. (2005) Tissue-type plasminogen activator is upregulated in metastatic breast cancer cells exposed to insulin-like growth factor-I. Clin. Breast Cancer 6, 340-348 (Pubitemid 41715696)
    • (2005) Clinical Breast Cancer , vol.6 , Issue.4 , pp. 340-348
    • Chernicky, C.L.1    Yi, L.2    Tan, H.3    Ilan, J.4
  • 47
    • 18844373409 scopus 로고    scopus 로고
    • Tissue plasminogen activator expression in meningiomas and glioblastomas
    • DOI 10.1016/j.clineuro.2004.09.010, PII S0303846704001350
    • Goh, K. Y., Poon, W. S., Chan, D. T. and Ip, C. P. (2005) Tissue plasminogen activator expression in meningiomas and glioblastomas. Clin. Neurol. Neurosurg. 107, 296-300 (Pubitemid 40693505)
    • (2005) Clinical Neurology and Neurosurgery , vol.107 , Issue.4 , pp. 296-300
    • Goh, K.Y.C.1    Poon, W.S.2    Chan, D.T.M.3    Chui, P.I.4
  • 48
    • 33745305950 scopus 로고    scopus 로고
    • Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples
    • Laurell, H., Bouisson, M., Berthelemy, P., Rochaix, P., Dejean, S., Besse, P., Susini, C., Pradayrol, L., Vaysse, N. and Buscail, L. (2006) Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples. World J. Gastroenterol. 12, 3344-3351 (Pubitemid 43933778)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.21 , pp. 3344-3351
    • Laurell, H.1    Bouisson, M.2    Berthelemy, P.3    Rochaix, P.4    Dejean, S.5    Besse, P.6    Susini, C.7    Pradayrol, L.8    Vaysse, N.9    Buscail, L.10
  • 49
    • 33847671384 scopus 로고    scopus 로고
    • Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: Relation to prognosis and angiogenesis
    • DOI 10.1016/j.lungcan.2006.11.018, PII S0169500206006222
    • Offersen, B. V., Pfeiffer, P., Andreasen, P. and Overgaard, J. (2007) Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis. Lung Cancer 56, 43-50 (Pubitemid 46356642)
    • (2007) Lung Cancer , vol.56 , Issue.1 , pp. 43-50
    • Offersen, B.V.1    Pfeiffer, P.2    Andreasen, P.3    Overgaard, J.4
  • 50
    • 33847034860 scopus 로고    scopus 로고
    • Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer
    • Pulukuri, S. M., Estes, N., Patel, J. and Rao, J. S. (2007) Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer. Cancer Res. 67, 930-939
    • (2007) Cancer Res. , vol.67 , pp. 930-939
    • Pulukuri, S.M.1    Estes, N.2    Patel, J.3    Rao, J.S.4
  • 51
    • 0033946825 scopus 로고    scopus 로고
    • Urokinase plasminogen activator system gene expression is increased in human breast carcinoma and its bone metastases - A comparison of normal breast tissue, non-invasive carcinoma and osseous metastases
    • DOI 10.1023/A:1006445129195
    • Fisher, J. L., Field, C. L., Zhou, H., Harris, T. L., Henderson, M. A. and Choong, P. F. (2000) Urokinase plasminogen activator system gene expression is increased in human breast carcinoma and its bone metastases: a comparison of normal breast tissue, non-invasive and invasive carcinoma and osseous metastases. Breast Cancer Res. Treat. 61, 1-12 (Pubitemid 30440545)
    • (2000) Breast Cancer Research and Treatment , vol.61 , Issue.1 , pp. 1-12
    • Fisher, J.L.1    Field, C.L.2    Zhou, H.3    Harris, T.L.4    Henderson, M.A.5    Choong, P.F.M.6
  • 52
    • 0027361935 scopus 로고
    • Expression and localization of elements of the plasminogen activation system in benign breast disease and breast cancers
    • Jankun, J., Merrick, H. W. and Goldblatt, P. J. (1993) Expression and localization of elements of the plasminogen activation system in benign breast disease and breast cancers. J. Cell. Biochem. 53, 135-144 (Pubitemid 23294599)
    • (1993) Journal of Cellular Biochemistry , vol.53 , Issue.2 , pp. 135-144
    • Jankun, J.1    Merrick, H.W.2    Goldblatt, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.