메뉴 건너뛰기




Volumn 10, Issue , 2014, Pages 2105-2114

Age-associated decrease in global DNA methylation in patients with major depression

Author keywords

5 hydroxymethylcytosine; 5 methylcytosine; Antidepressant; Epigenetic; Gene modification; Mood disorder

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; CHLORPROMAZINE; DNA; IMIPRAMINE;

EID: 84910090768     PISSN: None     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/NDT.S71997     Document Type: Article
Times cited : (36)

References (60)
  • 1
    • 0033810465 scopus 로고    scopus 로고
    • Genetic epidemiology of major depression: Review and meta-analysis
    • Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry. 2000;157(10):1552-1562.
    • (2000) Am J Psychiatry. , vol.157 , Issue.10 , pp. 1552-1562
    • Sullivan, P.F.1    Neale, M.C.2    Kendler, K.S.3
  • 2
    • 84856181467 scopus 로고    scopus 로고
    • Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene-environment interactions, and epigenetics
    • Heim C, Binder EB. Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp Neurol. 2012;233(1):102-111.
    • (2012) Exp Neurol. , vol.233 , Issue.1 , pp. 102-111
    • Heim, C.1    Binder, E.B.2
  • 3
    • 3342989681 scopus 로고    scopus 로고
    • Epigenetic programming by maternal behavior
    • Weaver IC, Cervoni N, Champagne FA, et al. Epigenetic programming by maternal behavior. Nat Neurosci. 2004;7(8):847-854.
    • (2004) Nat Neurosci. , vol.7 , Issue.8 , pp. 847-854
    • Weaver, I.C.1    Cervoni, N.2    Champagne, F.A.3
  • 4
    • 83755180447 scopus 로고    scopus 로고
    • Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: A link with the severity and type of trauma
    • Perroud N, Paoloni-Giacobino A, Prada P, et al. Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma. Transl Psychiatry. 2011;1:e59.
    • (2011) Transl Psychiatry. , vol.1
    • Perroud, N.1    Paoloni-Giacobino, A.2    Prada, P.3
  • 5
    • 84888297890 scopus 로고    scopus 로고
    • Gestational environment programs adult depression-like behavior through methylation of the calcitonin gene-related peptide gene
    • Jiao J, Opal MD, Dulawa SC. Gestational environment programs adult depression-like behavior through methylation of the calcitonin gene-related peptide gene. Mol Psychiatry. 2013;18(12):1273-1280.
    • (2013) Mol Psychiatry. , vol.18 , Issue.12 , pp. 1273-1280
    • Jiao, J.1    Opal, M.D.2    Dulawa, S.C.3
  • 6
    • 79960310830 scopus 로고    scopus 로고
    • Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample
    • Uddin M, Koenen KC, Aiello AE, Wildman DE, de los Santos R, Galea S. Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample. Psychol Med. 2011;41(5):997-1007.
    • (2011) Psychol Med. , vol.41 , Issue.5 , pp. 997-1007
    • Uddin, M.1    Koenen, K.C.2    Aiello, A.E.3    Wildman, D.E.4    de los Santos, R.5    Galea, S.6
  • 7
    • 79955912262 scopus 로고    scopus 로고
    • Orexin expression and promoter-methylation in peripheral blood of patients suffering from major depressive disorder
    • Rotter A, Asemann R, Decker A, Kornhuber J, Biermann T. Orexin expression and promoter-methylation in peripheral blood of patients suffering from major depressive disorder. J Affect Disord. 2011;131(1-3):186-192.
    • (2011) J Affect Disord. , vol.131 , Issue.1-3 , pp. 186-192
    • Rotter, A.1    Asemann, R.2    Decker, A.3    Kornhuber, J.4    Biermann, T.5
  • 8
    • 80052287594 scopus 로고    scopus 로고
    • DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression
    • Fuchikami M, Morinobu S, Segawa M, et al. DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression. PLoS One. 2011;6(8):e23881.
    • (2011) PLoS One. , vol.6 , Issue.8
    • Fuchikami, M.1    Morinobu, S.2    Segawa, M.3
  • 9
    • 84863768068 scopus 로고    scopus 로고
    • DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression
    • Zill P, Baghai TC, Schüle C, et al. DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. PLoS One. 2012;7(7):e40479.
    • (2012) PLoS One. , vol.7 , Issue.7
    • Zill, P.1    Baghai, T.C.2    Schüle, C.3
  • 10
    • 84869096094 scopus 로고    scopus 로고
    • Epigenetics of the depressed brain: Role of histone acetylation and methylation
    • Sun HS, Kennedy PJ, Nestler EJ. Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacology. 2013;38(1):124-137.
    • (2013) Neuropsychopharmacology. , vol.38 , Issue.1 , pp. 124-137
    • Sun, H.S.1    Kennedy, P.J.2    Nestler, E.J.3
  • 11
    • 84874508475 scopus 로고    scopus 로고
    • Looking beyond the DNA sequence: The relevance of DNA methylation processes for the stress-diathesis model of depression
    • Booij L, Wang D, Levesque ML, Tremblay RE, Szyf M. Looking beyond the DNA sequence: the relevance of DNA methylation processes for the stress-diathesis model of depression. Philos Trans R Soc Lond B Biol Sci. 2013;368(1615):20120251.
    • (2013) Philos Trans R Soc Lond B Biol Sci. , vol.368 , Issue.1615
    • Booij, L.1    Wang, D.2    Levesque, M.L.3    Tremblay, R.E.4    Szyf, M.5
  • 12
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor TH. The DNA methyltransferases of mammals. Hum Mol Genet. 2000;9(16):2395-2402.
    • (2000) Hum Mol Genet. , vol.9 , Issue.16 , pp. 2395-2402
    • Bestor, T.H.1
  • 13
    • 77954842322 scopus 로고    scopus 로고
    • Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
    • Wu H, Coskun V, Tao J, et al. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science. 2010;329(5990):444-448.
    • (2010) Science. , vol.329 , Issue.5990 , pp. 444-448
    • Wu, H.1    Coskun, V.2    Tao, J.3
  • 14
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani M, Koh KP, Shen Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324(5929):930-935.
    • (2009) Science. , vol.324 , Issue.5929 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3
  • 15
    • 4043112183 scopus 로고    scopus 로고
    • Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
    • Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res. 2004;32(14):4100-4108.
    • (2004) Nucleic Acids Res. , vol.32 , Issue.14 , pp. 4100-4108
    • Valinluck, V.1    Tsai, H.H.2    Rogstad, D.K.3    Burdzy, A.4    Bird, A.5    Sowers, L.C.6
  • 16
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T. The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem. 2003;278(6):4035-4040.
    • (2003) J Biol Chem. , vol.278 , Issue.6 , pp. 4035-4040
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 18
    • 0038136913 scopus 로고    scopus 로고
    • Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1
    • Kimura H, Shiota K. Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1. J Biol Chem. 2003;278(7):4806-4812.
    • (2003) J Biol Chem. , vol.278 , Issue.7 , pp. 4806-4812
    • Kimura, H.1    Shiota, K.2
  • 19
    • 33847055935 scopus 로고    scopus 로고
    • Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
    • Valinluck V, Sowers LC. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res. 2007;67(3):946-950.
    • (2007) Cancer Res. , vol.67 , Issue.3 , pp. 946-950
    • Valinluck, V.1    Sowers, L.C.2
  • 20
    • 79960249232 scopus 로고    scopus 로고
    • Genomic mapping of 5-hydroxymethylcytosine in the human brain
    • Jin SG, Wu X, Li AX, Pfeifer GP. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res. 2011;39(12):5015-5024.
    • (2011) Nucleic Acids Res. , vol.39 , Issue.12 , pp. 5015-5024
    • Jin, S.G.1    Wu, X.2    Li, A.X.3    Pfeifer, G.P.4
  • 21
    • 84884241288 scopus 로고    scopus 로고
    • Tet1 is critical for neuronal activity-regulated gene expression and memory extinction
    • Rudenko A, Dawlaty MM, Seo J, et al. Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron. 2013;79(6):1109-1122.
    • (2013) Neuron. , vol.79 , Issue.6 , pp. 1109-1122
    • Rudenko, A.1    Dawlaty, M.M.2    Seo, J.3
  • 22
    • 84897059011 scopus 로고    scopus 로고
    • Decreased expression of ten-eleven translocation 1 protein is associated with some clinicopathological features in gastric cancer
    • Frycz BA, Murawa D, Borejsza-Wysocki M, et al. Decreased expression of ten-eleven translocation 1 protein is associated with some clinicopathological features in gastric cancer. Biomed Pharmacother. 2014;68(2):209-212.
    • (2014) Biomed Pharmacother. , vol.68 , Issue.2 , pp. 209-212
    • Frycz, B.A.1    Murawa, D.2    Borejsza-Wysocki, M.3
  • 23
    • 84255200412 scopus 로고    scopus 로고
    • 5-hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
    • Jin SG, Jiang Y, Qiu R, et al. 5-hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res. 2011;71(24):7360-7365.
    • (2011) Cancer Res. , vol.71 , Issue.24 , pp. 7360-7365
    • Jin, S.G.1    Jiang, Y.2    Qiu, R.3
  • 24
    • 84863393235 scopus 로고    scopus 로고
    • Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation
    • Kudo Y, Tateishi K, Yamamoto K, et al. Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation. Cancer Sci. 2012;103(4):670-676.
    • (2012) Cancer Sci. , vol.103 , Issue.4 , pp. 670-676
    • Kudo, Y.1    Tateishi, K.2    Yamamoto, K.3
  • 25
    • 84866419591 scopus 로고    scopus 로고
    • Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
    • Lian CG, Xu Y, Ceol C, et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell. 2012;150(6):1135-1146.
    • (2012) Cell. , vol.150 , Issue.6 , pp. 1135-1146
    • Lian, C.G.1    Xu, Y.2    Ceol, C.3
  • 26
    • 84866755324 scopus 로고    scopus 로고
    • Effect of aging on 5-hydroxymethylcytosine in brain mitochondria
    • Dzitoyeva S, Chen H, Manev H. Effect of aging on 5-hydroxymethylcytosine in brain mitochondria. Neurobiol Aging. 2012;33(12):2881-2891.
    • (2012) Neurobiol Aging. , vol.33 , Issue.12 , pp. 2881-2891
    • Dzitoyeva, S.1    Chen, H.2    Manev, H.3
  • 27
    • 84862994335 scopus 로고    scopus 로고
    • Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus
    • Chen H, Dzitoyeva S, Manev H. Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus. Restor Neurol Neurosci. 2012;30(3):237-245.
    • (2012) Restor Neurol Neurosci. , vol.30 , Issue.3 , pp. 237-245
    • Chen, H.1    Dzitoyeva, S.2    Manev, H.3
  • 28
    • 84924739457 scopus 로고    scopus 로고
    • Astrocytic abnormalities and global DNA methylation patterns in depression and suicide
    • Epub Mar 25
    • Nagy C, Suderman M, Yang J, et al. Astrocytic abnormalities and global DNA methylation patterns in depression and suicide. Mol Psychiatry. Epub 2014 Mar 25.
    • (2014) Mol Psychiatry.
    • Nagy, C.1    Suderman, M.2    Yang, J.3
  • 29
    • 84905980080 scopus 로고    scopus 로고
    • Hypermethylation in the ZBTB20 gene is associated with major depressive disorder
    • Davies MN, Krause L, Bell JT, et al; UK Brain Expression Consortium. Hypermethylation in the ZBTB20 gene is associated with major depressive disorder. Genome Biol. 2014;15(4):R56.
    • (2014) Genome Biol. , vol.15 , Issue.4
    • Davies, M.N.1    Krause, L.2    Bell, J.T.3
  • 30
    • 84869839291 scopus 로고    scopus 로고
    • Age-associated decrease in serum glial cell line-derived neurotrophic factor levels in patients with major depressive disorder
    • Tseng PT, Lee Y, Lin PY. Age-associated decrease in serum glial cell line-derived neurotrophic factor levels in patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013;40:334-339.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry. , vol.40 , pp. 334-339
    • Tseng, P.T.1    Lee, Y.2    Lin, P.Y.3
  • 31
    • 33644530053 scopus 로고    scopus 로고
    • Efficacy and tolerability of controlled-release paroxetine in the treatment of severe depression: Post hoc analysis of pooled data from a subset of subjects in four double-blind clinical trials
    • Dunner DL, Lipschitz A, Pitts CD, Davies JT. Efficacy and tolerability of controlled-release paroxetine in the treatment of severe depression: post hoc analysis of pooled data from a subset of subjects in four double-blind clinical trials. Clin Ther. 2005;27(12):1901-1911.
    • (2005) Clin Ther. , vol.27 , Issue.12 , pp. 1901-1911
    • Dunner, D.L.1    Lipschitz, A.2    Pitts, C.D.3    Davies, J.T.4
  • 32
    • 57049151378 scopus 로고    scopus 로고
    • The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder
    • Arnold LM, Meyers AL, Sunderajan P, et al. The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder. Ann Clin Psychiatry. 2008;20(4):187-193.
    • (2008) Ann Clin Psychiatry. , vol.20 , Issue.4 , pp. 187-193
    • Arnold, L.M.1    Meyers, A.L.2    Sunderajan, P.3
  • 33
    • 84871593642 scopus 로고    scopus 로고
    • The effect of initial duloxetine dosing strategy on nausea in Korean patients with major depressive disorder
    • Lee MS, Ahn YM, Chung S, Walton R, Raskin J, Kim MS. The effect of initial duloxetine dosing strategy on nausea in Korean patients with major depressive disorder. Psychiatry Investig. 2012;9(4):391-399.
    • (2012) Psychiatry Investig. , vol.9 , Issue.4 , pp. 391-399
    • Lee, M.S.1    Ahn, Y.M.2    Chung, S.3    Walton, R.4    Raskin, J.5    Kim, M.S.6
  • 34
    • 74549148317 scopus 로고    scopus 로고
    • A follow-up study on features of sensory gating P50 in treatment-resistant depression patients
    • Wang Y, Fang YR, Chen XS, et al. A follow-up study on features of sensory gating P50 in treatment-resistant depression patients. Chin Med J (Engl). 2009;122(24):2956-2960.
    • (2009) Chin Med J (Engl). , vol.122 , Issue.24 , pp. 2956-2960
    • Wang, Y.1    Fang, Y.R.2    Chen, X.S.3
  • 35
    • 0025011490 scopus 로고
    • Internal consistency and factor structure of the Chinese Health Questionnaire
    • Cheng TA, Wu JT, Chong MY, Williams P. Internal consistency and factor structure of the Chinese Health Questionnaire. Acta Psychiatr Scand. 1990;82(4):304-308.
    • (1990) Acta Psychiatr Scand. , vol.82 , Issue.4 , pp. 304-308
    • Cheng, T.A.1    Wu, J.T.2    Chong, M.Y.3    Williams, P.4
  • 36
    • 0024379394 scopus 로고
    • Validation of 30- and 12-item versions of the Chinese Health Questionnaire (CHQ) in patients admitted for general health screening
    • Chong MY, Wilkinson G. Validation of 30- and 12-item versions of the Chinese Health Questionnaire (CHQ) in patients admitted for general health screening. Psychol Med. 1989;19(2):495-505.
    • (1989) Psychol Med. , vol.19 , Issue.2 , pp. 495-505
    • Chong, M.Y.1    Wilkinson, G.2
  • 37
    • 0032970133 scopus 로고    scopus 로고
    • Treatment resistant depression: Methodological overview and operational criteria
    • Souery D, Amsterdam J, de Montigny C, et al. Treatment resistant depression: methodological overview and operational criteria. Eur Neuropsychopharmacol. 1999;9(1-2):83-91.
    • (1999) Eur Neuropsychopharmacol. , vol.9 , Issue.1-2 , pp. 83-91
    • Souery, D.1    Amsterdam, J.2    de Montigny, C.3
  • 38
    • 0032901648 scopus 로고    scopus 로고
    • Effectiveness of antidepressants. Meta-analysis of dose-effect relationships in randomised clinical trials
    • Bollini P, Pampallona S, Tibaldi G, Kupelnick B, Munizza C. Effectiveness of antidepressants. Meta-analysis of dose-effect relationships in randomised clinical trials. Br J Psychiatry. 1999;174:297-303.
    • (1999) Br J Psychiatry. , vol.174 , pp. 297-303
    • Bollini, P.1    Pampallona, S.2    Tibaldi, G.3    Kupelnick, B.4    Munizza, C.5
  • 39
    • 0038266756 scopus 로고    scopus 로고
    • Chlorpromazine equivalent doses for the newer atypical antipsychotics
    • Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry. 2003;64(6):663-667.
    • (2003) J Clin Psychiatry. , vol.64 , Issue.6 , pp. 663-667
    • Woods, S.W.1
  • 40
    • 0024552485 scopus 로고
    • Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA
    • Drinkwater RD, Blake TJ, Morley AA, Turner DR. Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA. Mutat Res. 1989;219(1):29-37.
    • (1989) Mutat Res. , vol.219 , Issue.1 , pp. 29-37
    • Drinkwater, R.D.1    Blake, T.J.2    Morley, A.A.3    Turner, D.R.4
  • 41
    • 0024988560 scopus 로고
    • Quantitative changes in T cell DNA methylation occur during differentiation and ageing
    • Golbus J, Palella TD, Richardson BC. Quantitative changes in T cell DNA methylation occur during differentiation and ageing. Eur J Immunol. 1990;20(8):1869-1872.
    • (1990) Eur J Immunol. , vol.20 , Issue.8 , pp. 1869-1872
    • Golbus, J.1    Palella, T.D.2    Richardson, B.C.3
  • 42
    • 34548130797 scopus 로고    scopus 로고
    • Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: A potential link between epigenetics and schizophrenia
    • Shimabukuro M, Sasaki T, Imamura A, et al. Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: a potential link between epigenetics and schizophrenia. J Psychiatr Res. 2007;41(12):1042-1046.
    • (2007) J Psychiatr Res. , vol.41 , Issue.12 , pp. 1042-1046
    • Shimabukuro, M.1    Sasaki, T.2    Imamura, A.3
  • 43
    • 33845873321 scopus 로고    scopus 로고
    • Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: A control study using rats
    • Shimabukuro M, Jinno Y, Fuke C, Okazaki Y. Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: a control study using rats. Behav Brain Funct. 2006;2:37.
    • (2006) Behav Brain Funct. , vol.2 , pp. 37
    • Shimabukuro, M.1    Jinno, Y.2    Fuke, C.3    Okazaki, Y.4
  • 44
    • 43049104493 scopus 로고    scopus 로고
    • No association between global leukocyte DNA methylation and homocysteine levels in schizophrenia patients
    • Bromberg A, Levine J, Nemetz B, Belmaker RH, Agam G. No association between global leukocyte DNA methylation and homocysteine levels in schizophrenia patients. Schizophr Res. 2008;101(1-3):50-57.
    • (2008) Schizophr Res. , vol.101 , Issue.1-3 , pp. 50-57
    • Bromberg, A.1    Levine, J.2    Nemetz, B.3    Belmaker, R.H.4    Agam, G.5
  • 45
    • 84896732939 scopus 로고    scopus 로고
    • Methylome-wide association study of schizophrenia: Identifying blood biomarker signatures of environmental insults
    • Aberg KA, McClay JL, Nerella S, et al. Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults. JAMA Psychiatry. 2014;71(3):255-264.
    • (2014) JAMA Psychiatry. , vol.71 , Issue.3 , pp. 255-264
    • Aberg, K.A.1    McClay, J.L.2    Nerella, S.3
  • 46
    • 84910042345 scopus 로고    scopus 로고
    • Aberrant DNA methylation of blood in schizophrenia by adjusting for estimated cellular proportions
    • Epub Jul 23
    • Kinoshita M, Numata S, Tajima A, et al. Aberrant DNA methylation of blood in schizophrenia by adjusting for estimated cellular proportions. Neuromolecular Med. Epub 2014 Jul 23.
    • (2014) Neuromolecular Med.
    • Kinoshita, M.1    Numata, S.2    Tajima, A.3
  • 47
    • 69949114948 scopus 로고    scopus 로고
    • Global leukocyte DNA methylation is not altered in euthymic bipolar patients
    • Bromberg A, Bersudsky Y, Levine J, Agam G. Global leukocyte DNA methylation is not altered in euthymic bipolar patients. J Affect Disord. 2009;118(1-3):234-239.
    • (2009) J Affect Disord. , vol.118 , Issue.1-3 , pp. 234-239
    • Bromberg, A.1    Bersudsky, Y.2    Levine, J.3    Agam, G.4
  • 48
    • 39149100275 scopus 로고    scopus 로고
    • Global DNA methylation is influenced by smoking behaviour
    • Hillemacher T, Frieling H, Moskau S, et al. Global DNA methylation is influenced by smoking behaviour. Eur Neuropsychopharmacol. 2008;18(4):295-298.
    • (2008) Eur Neuropsychopharmacol. , vol.18 , Issue.4 , pp. 295-298
    • Hillemacher, T.1    Frieling, H.2    Moskau, S.3
  • 49
    • 84877850278 scopus 로고    scopus 로고
    • Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
    • Mehta D, Klengel T, Conneely KN, et al. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proc Natl Acad Sci U S A. 2013;110(20):8302-8307.
    • (2013) Proc Natl Acad Sci U S A. , vol.110 , Issue.20 , pp. 8302-8307
    • Mehta, D.1    Klengel, T.2    Conneely, K.N.3
  • 51
    • 84873050679 scopus 로고    scopus 로고
    • Promoter methylation and age-related downregulation of Klotho in rhesus monkey
    • King GD, Rosene DL, Abraham CR. Promoter methylation and age-related downregulation of Klotho in rhesus monkey. Age (Dordr). 2012;34(6):1405-1419.
    • (2012) Age (Dordr). , vol.34 , Issue.6 , pp. 1405-1419
    • King, G.D.1    Rosene, D.L.2    Abraham, C.R.3
  • 52
    • 84876124887 scopus 로고    scopus 로고
    • Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases
    • Sundar IK, Yao H, Rahman I. Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. Antioxid Redox Signal. 2013;18(15):1956-1971.
    • (2013) Antioxid Redox Signal. , vol.18 , Issue.15 , pp. 1956-1971
    • Sundar, I.K.1    Yao, H.2    Rahman, I.3
  • 53
    • 84865362095 scopus 로고    scopus 로고
    • Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria
    • Sanchez-Roman I, Gómez A, Pérez I, et al. Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria. Biogerontology. 2012;13(4):399-411.
    • (2012) Biogerontology. , vol.13 , Issue.4 , pp. 399-411
    • Sanchez-Roman, I.1    Gómez, A.2    Pérez, I.3
  • 54
    • 84868557877 scopus 로고    scopus 로고
    • Epigenetic genome-wide association methylation in aging and longevity
    • Ben-Avraham D, Muzumdar RH, Atzmon G. Epigenetic genome-wide association methylation in aging and longevity. Epigenomics. 2012;4(5):503-509.
    • (2012) Epigenomics. , vol.4 , Issue.5 , pp. 503-509
    • Ben-Avraham, D.1    Muzumdar, R.H.2    Atzmon, G.3
  • 55
    • 82255192294 scopus 로고    scopus 로고
    • 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
    • Szulwach KE, Li X, Li Y, et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci. 2011;14(12):1607-1616.
    • (2011) Nat Neurosci. , vol.14 , Issue.12 , pp. 1607-1616
    • Szulwach, K.E.1    Li, X.2    Li, Y.3
  • 56
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature. 2010;466(7310):1129-1133.
    • (2010) Nature. , vol.466 , Issue.7310 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 57
    • 84861077168 scopus 로고    scopus 로고
    • Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression
    • Melas PA, Rogdaki M, Lennartsson A, et al. Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. Int J Neuropsychopharmacol. 2012;15(5):669-679.
    • (2012) Int J Neuropsychopharmacol. , vol.15 , Issue.5 , pp. 669-679
    • Melas, P.A.1    Rogdaki, M.2    Lennartsson, A.3
  • 58
    • 79958039842 scopus 로고    scopus 로고
    • Genes, environment, and individual differences in responding to treatment for depression
    • Uher R. Genes, environment, and individual differences in responding to treatment for depression. Harv Rev Psychiatry. 2011;19(3):109-124.
    • (2011) Harv Rev Psychiatry. , vol.19 , Issue.3 , pp. 109-124
    • Uher, R.1
  • 59
    • 82155191318 scopus 로고    scopus 로고
    • Serum Brain-derived neurotrophirc factor (Bdnf): The severity and symptomatic dimensions of depression
    • Jevtovic S, Karlovic D, Mihaljevic-Peles A, Seric V, Vrkic N, Jaksic N. Serum Brain-derived neurotrophirc factor (Bdnf): the severity and symptomatic dimensions of depression. Psychiatr Danub. 2011;23(4):363-369.
    • (2011) Psychiatr Danub. , vol.23 , Issue.4 , pp. 363-369
    • Jevtovic, S.1    Karlovic, D.2    Mihaljevic-Peles, A.3    Seric, V.4    Vrkic, N.5    Jaksic, N.6
  • 60
    • 19244374612 scopus 로고    scopus 로고
    • Differentiating moderate and severe depression using the Montgomery-Asberg depression rating scale (MADRS)
    • Muller MJ, Himmerich H, Kienzle B, Szegedi A. Differentiating moderate and severe depression using the Montgomery-Asberg depression rating scale (MADRS). J Affect Disord. 2003;77(3):255-260.
    • (2003) J Affect Disord. , vol.77 , Issue.3 , pp. 255-260
    • Muller, M.J.1    Himmerich, H.2    Kienzle, B.3    Szegedi, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.