Systematic comparison of molecular conformations of H+, K+-ATPase reveals an important contribution of the A-M2 linker for the luminal gating

Journal of Biological Chemistry

Volumn 289, Issue 44, 2014, Pages 30590-30601

  Abe, Kazuhiro ^a   Tani, Kazutoshi ^a   Fujiyoshi, Yoshinori ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ELECTRON MICROSCOPES; FLUORINE COMPOUNDS; MEDICAL IMAGING;

AZIMUTHAL POSITION; CRYO-ELECTRON MICROSCOPY; ELECTRON CRYSTALLOGRAPHY; MAGNESIUM FLUORIDE; MOLECULAR CONFORMATION; SARCOPLASMIC RETICULUM; TRANSMEMBRANE HELICES; TWO-DIMENSIONAL CRYSTALS;

CONFORMATIONS;

8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ALUMINUM FLUORIDE; BERYLLIUM FLUORIDE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; INORGANIC SALT; MAGNESIUM FLUORIDE; PHOSPHATE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; ANTIULCER AGENT; IMIDAZOLE DERIVATIVE; PROTEIN BINDING; PROTON PUMP INHIBITOR;

ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTALLIZATION; CYTOPLASM; ENZYME CONFORMATION; FLUORESCENCE; PROTEIN DOMAIN; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVE SITE; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; SWINE;

ANIMALS; ANTI-ULCER AGENTS; CATALYTIC DOMAIN; CRYOELECTRON MICROSCOPY; H(+)-K(+)-EXCHANGING ATPASE; IMIDAZOLES; ION CHANNEL GATING; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTON PUMP INHIBITORS; SUS SCROFA;

EID: 84910089272     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.584623     Document Type: Article

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