Crystal structure of the high-affinity Na+,K+-ATPase- ouabain complex with Mg2+ bound in the cation binding site

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 27, 2013, Pages 10958-10963

  Laursen, Mette ^a,b   Yatime, Laure ^a,b   Nissen, Poul ^a,b   Fedosova, Natalya U ^a,b  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Cardiac glycosides; Crystallography; Membrane proteins; Phosphoenzyme

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ISOLEUCINE; MAGNESIUM ION; OUABAIN; RUBIDIUM ION; STEROID; VALINE;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CATION TRANSPORT; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; DRUG BINDING SITE; DRUG STRUCTURE; HYDROGEN BOND; KIDNEY; MOLECULAR INTERACTION; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SWINE;

CARDIAC GLYCOSIDES; CRYSTALLOGRAPHY; MEMBRANE PROTEINS; PHOSPHOENZYME;

ANIMALS; BINDING SITES; CARDIOTONIC AGENTS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MAGNESIUM; MODELS, MOLECULAR; OUABAIN; POTASSIUM; PROTEIN CONFORMATION; SODIUM-POTASSIUM-EXCHANGING ATPASE; SWINE;

ANIMALIA; STROPHANTHUS GRATUS; SUIDAE;

EID: 84879701596     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222308110     Document Type: Article

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