Constant rate of p53 tetramerization in response to DNA damage controls the p53 response

Molecular Systems Biology

Volumn 10, Issue 10, 2014, Pages

  Gaglia, Giorgio ^a   Lahav, Galit ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DNA damage; Fluorescence imaging; P53 dynamics; Single cells; Tetramers

Indexed keywords

APOPTOSIS REPRESSOR WITH CASPASE RECRUITMENT DOMAIN; BINDING PROTEIN; PROTEIN P53; SMALL INTERFERING RNA; TETRAMER; YELLOW FLUORESCENT PROTEIN; ACTIVITY REGULATED CYTOSKELETAL-ASSOCIATED PROTEIN; CYTOSKELETON PROTEIN; NERVE PROTEIN; TP53 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; MCF 7 CELL LINE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; REGULATORY MECHANISM; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROTEIN MULTIMERIZATION; SPECTROFLUOROMETRY; TIME LAPSE IMAGING;

CYTOSKELETAL PROTEINS; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMANS; MCF-7 CELLS; NERVE TISSUE PROTEINS; PROTEIN MULTIMERIZATION; SPECTROMETRY, FLUORESCENCE; TIME-LAPSE IMAGING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84910036204     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20145168     Document Type: Article

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