메뉴 건너뛰기




Volumn 278, Issue , 2015, Pages 453-461

The effects of Ginkgo biloba extract on cognitive functions in aged female rats: The role of oxidative stress and brain-derived neurotrophic factor

Author keywords

Aging; BDNF; Cognitive function; Ginkgo biloba; Memory; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BRAIN DERIVED NEUROTROPHIC FACTOR; GINKGO BILOBA EXTRACT; GLUTATHIONE; MALONALDEHYDE; PLACEBO; SUPEROXIDE DISMUTASE; 8-OXO-7-HYDRODEOXYGUANOSINE; DEOXYGUANOSINE; PLANT EXTRACT;

EID: 84910000522     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.10.032     Document Type: Article
Times cited : (59)

References (71)
  • 1
    • 84883278681 scopus 로고    scopus 로고
    • Anti-amnestic properties of Ginkgo biloba extract on impaired memory function induced by aluminum in rats
    • Abd-Elhady R.M., Elsheikh A.M., Khalifa A.E. Anti-amnestic properties of Ginkgo biloba extract on impaired memory function induced by aluminum in rats. Int J Dev Neurosci 2013, 31:598-607.
    • (2013) Int J Dev Neurosci , vol.31 , pp. 598-607
    • Abd-Elhady, R.M.1    Elsheikh, A.M.2    Khalifa, A.E.3
  • 3
    • 0031590580 scopus 로고    scopus 로고
    • The ageing brain: normal and abnormal memory
    • Albert M.S. The ageing brain: normal and abnormal memory. Philos Trans R Soc Lond B: Biol Sci 1997, 352:1703-1709.
    • (1997) Philos Trans R Soc Lond B: Biol Sci , vol.352 , pp. 1703-1709
    • Albert, M.S.1
  • 4
    • 0034121829 scopus 로고    scopus 로고
    • The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid
    • Bastianetto S., Ramassamy C., Doré S., Christen Y., Poirier J., Quirion R. The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid. Eur J Neurosci 2000, 12:1882-1890.
    • (2000) Eur J Neurosci , vol.12 , pp. 1882-1890
    • Bastianetto, S.1    Ramassamy, C.2    Doré, S.3    Christen, Y.4    Poirier, J.5    Quirion, R.6
  • 5
    • 0034122940 scopus 로고    scopus 로고
    • The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C
    • Bastianetto S., Zheng W.H., Quirion R. The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C. J Neurochem 2000, 74:2268-2277.
    • (2000) J Neurochem , vol.74 , pp. 2268-2277
    • Bastianetto, S.1    Zheng, W.H.2    Quirion, R.3
  • 6
    • 84867741460 scopus 로고    scopus 로고
    • Age and sex affect spatial and emotional behaviors in rats: the role of repeated elevated plus maze test
    • Belviranli M., Atalik K.E., Okudan N., Gökbel H. Age and sex affect spatial and emotional behaviors in rats: the role of repeated elevated plus maze test. Neuroscience 2012, 227:1-9.
    • (2012) Neuroscience , vol.227 , pp. 1-9
    • Belviranli, M.1    Atalik, K.E.2    Okudan, N.3    Gökbel, H.4
  • 7
    • 84878564756 scopus 로고    scopus 로고
    • Curcumin improves spatial memory and decreases oxidative damage in aged female rats
    • Belviranli M., Okudan N., Atalik K.E., Öz M. Curcumin improves spatial memory and decreases oxidative damage in aged female rats. Biogerontology 2013, 14:187-196.
    • (2013) Biogerontology , vol.14 , pp. 187-196
    • Belviranli, M.1    Okudan, N.2    Atalik, K.E.3    Öz, M.4
  • 8
    • 78650719643 scopus 로고    scopus 로고
    • Spatial and emotional memory in aged rats: a behavioral-statistical analysis
    • Bergado J.A., Almaguer W., Rojas Y., Capdevila V., Frey J.U. Spatial and emotional memory in aged rats: a behavioral-statistical analysis. Neuroscience 2011, 172:256-269.
    • (2011) Neuroscience , vol.172 , pp. 256-269
    • Bergado, J.A.1    Almaguer, W.2    Rojas, Y.3    Capdevila, V.4    Frey, J.U.5
  • 9
    • 0027359334 scopus 로고
    • Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
    • Bowling A.C., Schulz J.B., Brown R.H., Beal M.F. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J Neurochem 1993, 61:2322-2325.
    • (1993) J Neurochem , vol.61 , pp. 2322-2325
    • Bowling, A.C.1    Schulz, J.B.2    Brown, R.H.3    Beal, M.F.4
  • 10
    • 79953662385 scopus 로고    scopus 로고
    • Immune system to brain signaling: neuropsychopharmacological implications
    • Capuron L., Miller A.H. Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol Ther 2011, 130:226-238.
    • (2011) Pharmacol Ther , vol.130 , pp. 226-238
    • Capuron, L.1    Miller, A.H.2
  • 11
    • 0036728025 scopus 로고    scopus 로고
    • Bilobalide, a component of the Ginkgo biloba extract (EGb 761), protects against neuronal death in global brain ischemia and in glutamate-induced excitotoxicity
    • Chandrasekaran K., Mehrabian Z., Spinnewyn B., Chinopoulos C., Drieu K., Fiskum G. Bilobalide, a component of the Ginkgo biloba extract (EGb 761), protects against neuronal death in global brain ischemia and in glutamate-induced excitotoxicity. Cell Mol Biol (Noisy-le-grand) 2002, 48:663-669.
    • (2002) Cell Mol Biol (Noisy-le-grand) , vol.48 , pp. 663-669
    • Chandrasekaran, K.1    Mehrabian, Z.2    Spinnewyn, B.3    Chinopoulos, C.4    Drieu, K.5    Fiskum, G.6
  • 12
    • 0031010596 scopus 로고    scopus 로고
    • Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow
    • Cohen G., Farooqui R., Kesler N. Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow. Proc Natl Acad Sci USA 1997, 94:4890-4894.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4890-4894
    • Cohen, G.1    Farooqui, R.2    Kesler, N.3
  • 14
    • 0034232147 scopus 로고    scopus 로고
    • Ginkgo biloba extract (EGb 761) and CNS functions: basic studies and clinical applications
    • DeFeudis F.V., Drieu K. Ginkgo biloba extract (EGb 761) and CNS functions: basic studies and clinical applications. Curr Drug Targets 2000, 1:25-58.
    • (2000) Curr Drug Targets , vol.1 , pp. 25-58
    • DeFeudis, F.V.1    Drieu, K.2
  • 15
    • 0034888287 scopus 로고    scopus 로고
    • Applications of the Morris water maze in the study of learning and memory
    • D'Hooge R., De Deyn P.P. Applications of the Morris water maze in the study of learning and memory. Brain Res Brain Res Rev 2001, 36:60-90.
    • (2001) Brain Res Brain Res Rev , vol.36 , pp. 60-90
    • D'Hooge, R.1    De Deyn, P.P.2
  • 17
    • 84863885261 scopus 로고    scopus 로고
    • Mitochondrial effects of Ginkgo biloba extract
    • Eckert A. Mitochondrial effects of Ginkgo biloba extract. Int Psychogeriatr 2012, 24:S18-S20.
    • (2012) Int Psychogeriatr , vol.24 , pp. S18-S20
    • Eckert, A.1
  • 18
    • 60549086571 scopus 로고    scopus 로고
    • Aging: an important factor for the pathogenesis of neurodegenerative diseases
    • Farooqui T., Farooqui A.A. Aging: an important factor for the pathogenesis of neurodegenerative diseases. Mech Ageing Dev 2009, 130:203-215.
    • (2009) Mech Ageing Dev , vol.130 , pp. 203-215
    • Farooqui, T.1    Farooqui, A.A.2
  • 19
    • 84865755929 scopus 로고    scopus 로고
    • Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's disease
    • Foster P.P., Rosenblatt K.P., Kuljiš R.O. Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's disease. Front Neurol 2011, 2:28.
    • (2011) Front Neurol , vol.2 , pp. 28
    • Foster, P.P.1    Rosenblatt, K.P.2    Kuljiš, R.O.3
  • 20
    • 0026027012 scopus 로고
    • Lack of effect of age and dietary restriction on DNA single-stranded breaks in brain, liver, and kidney of (C3H x C57BL/10)F1 mice
    • Fu C.S., Harris S.B., Wilhelmi P., Walford R.L. Lack of effect of age and dietary restriction on DNA single-stranded breaks in brain, liver, and kidney of (C3H x C57BL/10)F1 mice. J Gerontol 1991, 46:78-80.
    • (1991) J Gerontol , vol.46 , pp. 78-80
    • Fu, C.S.1    Harris, S.B.2    Wilhelmi, P.3    Walford, R.L.4
  • 21
    • 18044392043 scopus 로고    scopus 로고
    • Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rats
    • Gong Q.H., Wu Q., Huang X.N., Sun A.S., Shi J.S. Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rats. Life Sci 2005, 77:140-148.
    • (2005) Life Sci , vol.77 , pp. 140-148
    • Gong, Q.H.1    Wu, Q.2    Huang, X.N.3    Sun, A.S.4    Shi, J.S.5
  • 22
    • 0035090135 scopus 로고    scopus 로고
    • Prevention of neuronal cell damage induced by oxidative stress in-vitro: effect of different Ginkgo biloba extracts
    • Guidetti C., Paracchini S., Lucchini S., Cambieri M., Marzatico F. Prevention of neuronal cell damage induced by oxidative stress in-vitro: effect of different Ginkgo biloba extracts. J Pharm Pharmacol 2001, 53:387-392.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 387-392
    • Guidetti, C.1    Paracchini, S.2    Lucchini, S.3    Cambieri, M.4    Marzatico, F.5
  • 23
    • 84905392606 scopus 로고    scopus 로고
    • Age-related learning and memory deficits in rats: role of altered brain neurotransmitters, acetylcholinesterase activity and changes in antioxidant defense system
    • Haider S., Saleem S., Perveen T., Tabassum S., Batool Z., Sadir S., et al. Age-related learning and memory deficits in rats: role of altered brain neurotransmitters, acetylcholinesterase activity and changes in antioxidant defense system. Age (Dordr) 2014, 36:9653.
    • (2014) Age (Dordr) , vol.36 , pp. 9653
    • Haider, S.1    Saleem, S.2    Perveen, T.3    Tabassum, S.4    Batool, Z.5    Sadir, S.6
  • 24
    • 14844285338 scopus 로고    scopus 로고
    • Modulation of age-associated oxidative DNA damage in rat brain cerebral cortex, striatum and hippocampus by l-carnitine
    • Haripriya D., Sangeetha P., Kanchana A., Balu M., Panneerselvam C. Modulation of age-associated oxidative DNA damage in rat brain cerebral cortex, striatum and hippocampus by l-carnitine. Exp Gerontol 2005, 40:129-135.
    • (2005) Exp Gerontol , vol.40 , pp. 129-135
    • Haripriya, D.1    Sangeetha, P.2    Kanchana, A.3    Balu, M.4    Panneerselvam, C.5
  • 26
    • 0033460182 scopus 로고    scopus 로고
    • Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761)
    • Hoyer S., Lannert H., Nöldner M., Chatterjee S.S. Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761). J Neural Transm 1999, 106:1171-1188.
    • (1999) J Neural Transm , vol.106 , pp. 1171-1188
    • Hoyer, S.1    Lannert, H.2    Nöldner, M.3    Chatterjee, S.S.4
  • 27
    • 0032126843 scopus 로고    scopus 로고
    • Oxidized phospholipids as a new landmark in atherosclerosis
    • Itabe H. Oxidized phospholipids as a new landmark in atherosclerosis. Prog Lipid Res 1998, 37:181-207.
    • (1998) Prog Lipid Res , vol.37 , pp. 181-207
    • Itabe, H.1
  • 29
    • 0142156732 scopus 로고    scopus 로고
    • An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice
    • Kuribara H., Weintraub S.T., Yoshihama T., Maruyama Y. An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice. J Nat Prod 2003, 66:1333-1337.
    • (2003) J Nat Prod , vol.66 , pp. 1333-1337
    • Kuribara, H.1    Weintraub, S.T.2    Yoshihama, T.3    Maruyama, Y.4
  • 30
    • 84881172705 scopus 로고    scopus 로고
    • Protective effect of bilobalide on learning and memory impairment in rats with vascular dementia
    • Li W.Z., Wu W.Y., Huang H., Wu Y.Y., Yin Y.Y. Protective effect of bilobalide on learning and memory impairment in rats with vascular dementia. Mol Med Rep 2013, 8:935-941.
    • (2013) Mol Med Rep , vol.8 , pp. 935-941
    • Li, W.Z.1    Wu, W.Y.2    Huang, H.3    Wu, Y.Y.4    Yin, Y.Y.5
  • 32
    • 84870426481 scopus 로고    scopus 로고
    • Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid receptors in male Kunming mice
    • Ma L., Wang S., Tai F., Yuan G., Wu R., Liu X., et al. Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid receptors in male Kunming mice. Phytomedicine 2012, 20:89-96.
    • (2012) Phytomedicine , vol.20 , pp. 89-96
    • Ma, L.1    Wang, S.2    Tai, F.3    Yuan, G.4    Wu, R.5    Liu, X.6
  • 33
    • 84855445646 scopus 로고    scopus 로고
    • The effect of Ginkgo biloba extract (EGb 761) on parameters of oxidative stress in different regions of aging rat brains after acute hypoxia
    • Martin R., Mozet C., Martin H., Welt K., Engel C., Fitzl G. The effect of Ginkgo biloba extract (EGb 761) on parameters of oxidative stress in different regions of aging rat brains after acute hypoxia. Aging Clin Exp Res 2011, 23:255-263.
    • (2011) Aging Clin Exp Res , vol.23 , pp. 255-263
    • Martin, R.1    Mozet, C.2    Martin, H.3    Welt, K.4    Engel, C.5    Fitzl, G.6
  • 34
    • 1342279441 scopus 로고    scopus 로고
    • Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons
    • Massieu L., Morán J., Christen Y. Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons. Brain Res 2004, 1002:76-85.
    • (2004) Brain Res , vol.1002 , pp. 76-85
    • Massieu, L.1    Morán, J.2    Christen, Y.3
  • 36
    • 0033374833 scopus 로고    scopus 로고
    • Lynch age-related changes in oxidative mechanisms and LTP are reversed by dietary manipulation
    • McGahon B.M., Murray C.A., Horrobin D.F. Lynch age-related changes in oxidative mechanisms and LTP are reversed by dietary manipulation. Neurobiol Aging 1999, 20:643-653.
    • (1999) Neurobiol Aging , vol.20 , pp. 643-653
    • McGahon, B.M.1    Murray, C.A.2    Horrobin, D.F.3
  • 37
    • 84856770110 scopus 로고    scopus 로고
    • Ginkgo extract EGb761 confers neuroprotection by reduction of glutamate release in ischemic brain
    • Mdzinarishvili A., Sumbria R., Lang D., Klein J. Ginkgo extract EGb761 confers neuroprotection by reduction of glutamate release in ischemic brain. J Pharm Pharm Sci 2012, 15:94-102.
    • (2012) J Pharm Pharm Sci , vol.15 , pp. 94-102
    • Mdzinarishvili, A.1    Sumbria, R.2    Lang, D.3    Klein, J.4
  • 39
    • 84863895230 scopus 로고    scopus 로고
    • Effects of the standardized Ginkgo biloba extract EGb 761* on neuroplasticity
    • Müller W.E., Heiser J., Leuner K. Effects of the standardized Ginkgo biloba extract EGb 761* on neuroplasticity. Int Psychogeriatr 2012, 24:S21-S24.
    • (2012) Int Psychogeriatr , vol.24 , pp. S21-S24
    • Müller, W.E.1    Heiser, J.2    Leuner, K.3
  • 40
    • 34548071368 scopus 로고    scopus 로고
    • Association between trait anxiety and endothelial function observed in elderly males but not in young males
    • Narita K., Murata T., Hamada T., Takahashi T., Kosaka H., Yoshida H., et al. Association between trait anxiety and endothelial function observed in elderly males but not in young males. Int Psychogeriatr 2007, 19:947-954.
    • (2007) Int Psychogeriatr , vol.19 , pp. 947-954
    • Narita, K.1    Murata, T.2    Hamada, T.3    Takahashi, T.4    Kosaka, H.5    Yoshida, H.6
  • 43
    • 0032412522 scopus 로고    scopus 로고
    • Dietary antioxidant supplementation reverses age-related neuronal changes
    • O'Donnell E., Lynch M.A. Dietary antioxidant supplementation reverses age-related neuronal changes. Neurobiol Aging 1998, 19:461-467.
    • (1998) Neurobiol Aging , vol.19 , pp. 461-467
    • O'Donnell, E.1    Lynch, M.A.2
  • 45
    • 0027090268 scopus 로고
    • Flow cytometric estimation of the effect of Ginkgo biloba extract on the content of hydrogen peroxide in dissociated mammalian brain neurons
    • Oyama Y., Ueha T., Hayashi A., Chikahisa L., Noda K. Flow cytometric estimation of the effect of Ginkgo biloba extract on the content of hydrogen peroxide in dissociated mammalian brain neurons. Jpn J Pharmacol 1992, 60:385-388.
    • (1992) Jpn J Pharmacol , vol.60 , pp. 385-388
    • Oyama, Y.1    Ueha, T.2    Hayashi, A.3    Chikahisa, L.4    Noda, K.5
  • 46
    • 0029928823 scopus 로고    scopus 로고
    • Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide
    • Oyama Y., Chikahisa L., Ueha T., Kanemaru K., Noda K. Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide. Brain Res 1996, 712:349-352.
    • (1996) Brain Res , vol.712 , pp. 349-352
    • Oyama, Y.1    Chikahisa, L.2    Ueha, T.3    Kanemaru, K.4    Noda, K.5
  • 47
    • 0342472188 scopus 로고    scopus 로고
    • Age-dependent effects of a chronic ultramild stress procedure on open-field behaviour in B6D2F1 female mice
    • Pardon M., Pérez-Diaz F., Joubert C., Cohen-Salmon C. Age-dependent effects of a chronic ultramild stress procedure on open-field behaviour in B6D2F1 female mice. Physiol Behav 2000, 70:7-13.
    • (2000) Physiol Behav , vol.70 , pp. 7-13
    • Pardon, M.1    Pérez-Diaz, F.2    Joubert, C.3    Cohen-Salmon, C.4
  • 48
    • 0030474286 scopus 로고    scopus 로고
    • Sex differences in performance in the Morris water maze and the effects of initial nonstationary hidden platform training
    • Perrot-Sinal T.S., Kostenuik M.A., Ossenkopp K.P., Kavaliers M. Sex differences in performance in the Morris water maze and the effects of initial nonstationary hidden platform training. Behav Neurosci 1996, 110:1309-1320.
    • (1996) Behav Neurosci , vol.110 , pp. 1309-1320
    • Perrot-Sinal, T.S.1    Kostenuik, M.A.2    Ossenkopp, K.P.3    Kavaliers, M.4
  • 49
    • 84856228497 scopus 로고    scopus 로고
    • Aerobic exercise prevents age-dependent cognitive decline and reduces anxiety-related behaviors in middle-aged and old rats
    • Pietrelli A., Lopez-Costa J., Goñi R., Brusco A., Basso N. Aerobic exercise prevents age-dependent cognitive decline and reduces anxiety-related behaviors in middle-aged and old rats. Neuroscience 2012, 202:252-266.
    • (2012) Neuroscience , vol.202 , pp. 252-266
    • Pietrelli, A.1    Lopez-Costa, J.2    Goñi, R.3    Brusco, A.4    Basso, N.5
  • 50
    • 15044355889 scopus 로고    scopus 로고
    • Effects of extract of Ginkgo biloba with venlafaxine on brain injury in a rat model of depression
    • Qin X.S., Jin K.H., Ding B.K., Xie S.F., Ma H. Effects of extract of Ginkgo biloba with venlafaxine on brain injury in a rat model of depression. Chin Med J (Engl) 2005, 118:391-397.
    • (2005) Chin Med J (Engl) , vol.118 , pp. 391-397
    • Qin, X.S.1    Jin, K.H.2    Ding, B.K.3    Xie, S.F.4    Ma, H.5
  • 51
    • 0030782744 scopus 로고    scopus 로고
    • Anxiety, defence and the elevated plus-maze
    • Rodgers R.J., Dalvi A. Anxiety, defence and the elevated plus-maze. Neurosci Biobehav Rev 1997, 21:801-810.
    • (1997) Neurosci Biobehav Rev , vol.21 , pp. 801-810
    • Rodgers, R.J.1    Dalvi, A.2
  • 52
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: plasticity, network dynamics, and cognition
    • Rosenzweig E.S., Barnes C.A. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol 2003, 69:143-179.
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 53
    • 0019131019 scopus 로고
    • Age-related changes in lipid peroxidation as measured by ethane, ethylene, butane and pentane in respired gases of rats
    • Sagai M., Ichinose T. Age-related changes in lipid peroxidation as measured by ethane, ethylene, butane and pentane in respired gases of rats. Life Sci 1980, 27:731-738.
    • (1980) Life Sci , vol.27 , pp. 731-738
    • Sagai, M.1    Ichinose, T.2
  • 54
    • 0031583896 scopus 로고    scopus 로고
    • Alterations in the activities of cerebral antioxidant enzymes of rat are related to aging
    • Sahoo A., Chainy G.B. Alterations in the activities of cerebral antioxidant enzymes of rat are related to aging. Int J Dev Neurosci 1997, 15:939-948.
    • (1997) Int J Dev Neurosci , vol.15 , pp. 939-948
    • Sahoo, A.1    Chainy, G.B.2
  • 56
    • 0028024339 scopus 로고
    • Behavioral changes following chronic myocardial infarction in rats
    • Schoemaker R.G., Smits J.F. Behavioral changes following chronic myocardial infarction in rats. Physiol Behav 1994, 56:585-589.
    • (1994) Physiol Behav , vol.56 , pp. 585-589
    • Schoemaker, R.G.1    Smits, J.F.2
  • 57
    • 84883036583 scopus 로고    scopus 로고
    • Neuroprotection by bilobalide in ischemia: improvement of mitochondrial function
    • Schwarzkopf T.M., Hagl S., Eckert G.P., Klein J. Neuroprotection by bilobalide in ischemia: improvement of mitochondrial function. Pharmazie 2013, 68:584-589.
    • (2013) Pharmazie , vol.68 , pp. 584-589
    • Schwarzkopf, T.M.1    Hagl, S.2    Eckert, G.P.3    Klein, J.4
  • 58
    • 0029556184 scopus 로고
    • Lipid peroxide, phospholipids, glutathione levels and superoxide dismutase activity in rat brain after ischaemia: effect of Ginkgo biloba extract
    • Seif-El-Nasr M., El-Fattah A.A. Lipid peroxide, phospholipids, glutathione levels and superoxide dismutase activity in rat brain after ischaemia: effect of Ginkgo biloba extract. Pharmacol Res 1995, 32:273-278.
    • (1995) Pharmacol Res , vol.32 , pp. 273-278
    • Seif-El-Nasr, M.1    El-Fattah, A.A.2
  • 59
    • 84857685524 scopus 로고    scopus 로고
    • An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat
    • Simpson J., Kelly J.P. An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat. Behav Brain Res 2012, 229:289-300.
    • (2012) Behav Brain Res , vol.229 , pp. 289-300
    • Simpson, J.1    Kelly, J.P.2
  • 60
    • 34547824397 scopus 로고    scopus 로고
    • Luo Y. EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease
    • Tchantchou F., Xu Y., Wu Y., Christen Y. Luo Y. EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease. FASEB J 2007, 21:2400-2408.
    • (2007) FASEB J , vol.21 , pp. 2400-2408
    • Tchantchou, F.1    Xu, Y.2    Wu, Y.3    Christen, Y.4
  • 61
    • 0345596416 scopus 로고    scopus 로고
    • Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging
    • Tian L., Cai Q., Wei H. Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging. Free Radic Biol Med 1998, 24:1477-1484.
    • (1998) Free Radic Biol Med , vol.24 , pp. 1477-1484
    • Tian, L.1    Cai, Q.2    Wei, H.3
  • 63
    • 0036742611 scopus 로고    scopus 로고
    • From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
    • Tyler W.J., Alonso M., Bramham C.R., Pozzo-Miller L.D. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn Mem 2002, 9:224-237.
    • (2002) Learn Mem , vol.9 , pp. 224-237
    • Tyler, W.J.1    Alonso, M.2    Bramham, C.R.3    Pozzo-Miller, L.D.4
  • 64
    • 20344405201 scopus 로고    scopus 로고
    • Gingko biloba extract diminishes stress-induced memory deficits in rats
    • Walesiuk A., Trofimiuk E., Braszko J.J. Gingko biloba extract diminishes stress-induced memory deficits in rats. Pharmacol Rep 2005, 57:176-187.
    • (2005) Pharmacol Rep , vol.57 , pp. 176-187
    • Walesiuk, A.1    Trofimiuk, E.2    Braszko, J.J.3
  • 65
    • 0000650706 scopus 로고
    • The Open-Field Test: a critical review
    • Walsh R.N., Cummins R.A. The Open-Field Test: a critical review. Psychol Bull 1976, 83:482-504.
    • (1976) Psychol Bull , vol.83 , pp. 482-504
    • Walsh, R.N.1    Cummins, R.A.2
  • 66
    • 33745015824 scopus 로고    scopus 로고
    • The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats
    • Wang Y., Wang L., Wu J., Cai J. The in vivo synaptic plasticity mechanism of EGb 761-induced enhancement of spatial learning and memory in aged rats. Br J Pharmacol 2006, 148:147-153.
    • (2006) Br J Pharmacol , vol.148 , pp. 147-153
    • Wang, Y.1    Wang, L.2    Wu, J.3    Cai, J.4
  • 67
    • 33748134645 scopus 로고    scopus 로고
    • Shannon Weickert C. BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan
    • Webster M.J., Herman M.M., Kleinman J.E. Shannon Weickert C. BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan. Gene Expr Patterns 2006, 6:941-951.
    • (2006) Gene Expr Patterns , vol.6 , pp. 941-951
    • Webster, M.J.1    Herman, M.M.2    Kleinman, J.E.3
  • 68
    • 0031987332 scopus 로고    scopus 로고
    • The effects of an extract of Ginkgo biloba, EGb 761, on cognitive behavior and longevity in the rat
    • Winter J.C. The effects of an extract of Ginkgo biloba, EGb 761, on cognitive behavior and longevity in the rat. Physiol Behav 1998, 63:425-433.
    • (1998) Physiol Behav , vol.63 , pp. 425-433
    • Winter, J.C.1
  • 69
    • 84876003481 scopus 로고    scopus 로고
    • Protective effects of bilobalide on Aβ(25-35) induced learning and memory impairments in male rats
    • Yin Y., Ren Y., Wu W., Wang Y., Cao M., Zhu Z., et al. Protective effects of bilobalide on Aβ(25-35) induced learning and memory impairments in male rats. Pharmacol Biochem Behav 2013, 106:77-84.
    • (2013) Pharmacol Biochem Behav , vol.106 , pp. 77-84
    • Yin, Y.1    Ren, Y.2    Wu, W.3    Wang, Y.4    Cao, M.5    Zhu, Z.6
  • 70
    • 84863900113 scopus 로고    scopus 로고
    • Effects of EGb761 on hippocamal synaptic plasticity of vascular dementia rats
    • Zhang L.Y., Wang Y.L. Effects of EGb761 on hippocamal synaptic plasticity of vascular dementia rats. Zhongguo Ying Yong Sheng Li Xue Za Zhi 2008, 24:36-40.
    • (2008) Zhongguo Ying Yong Sheng Li Xue Za Zhi , vol.24 , pp. 36-40
    • Zhang, L.Y.1    Wang, Y.L.2
  • 71
    • 84856609251 scopus 로고    scopus 로고
    • Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats
    • Zhang Z., Peng D., Zhu H., Wang X. Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats. Brain Res Bull 2012, 87:193-198.
    • (2012) Brain Res Bull , vol.87 , pp. 193-198
    • Zhang, Z.1    Peng, D.2    Zhu, H.3    Wang, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.