-
1
-
-
33646568784
-
Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
-
PMID: 16682732
-
Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006; 24: 2137-2150 [PMID: 16682732 DOI: 10.1200/JCO.2005.05.2308]
-
(2006)
J Clin Oncol
, vol.24
, pp. 2137-2150
-
-
Kamangar, F.1
Dores, G.M.2
Anderson, W.F.3
-
2
-
-
10044280517
-
Trends in mortality from major cancers in the European Union, including acceding countries, in 2004
-
PMID: 15526321
-
Levi F, Lucchini F, Negri E, La Vecchia C. Trends in mortality from major cancers in the European Union, including acceding countries, in 2004. Cancer 2004; 101: 2843-2850 [PMID: 15526321 DOI: 10.1002/cncr.20666]
-
(2004)
Cancer
, vol.101
, pp. 2843-2850
-
-
Levi, F.1
Lucchini, F.2
Negri, E.3
La Vecchia, C.4
-
3
-
-
0037263849
-
Gastric cancer epidemiology and risk factors
-
PMID: 12589864
-
Kelley JR, Duggan JM. Gastric cancer epidemiology and risk factors. J Clin Epidemiol 2003; 56: 1-9 [PMID: 12589864 DOI: 10.1016/S0895-4356(02)00534-6]
-
(2003)
J Clin Epidemiol
, vol.56
, pp. 1-9
-
-
Kelley, J.R.1
Duggan, J.M.2
-
4
-
-
14944385553
-
Global cancer statistics, 2002
-
PMID: 15761078
-
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108 [PMID: 15761078 DOI: 10.3322/canjclin.55.2.74]
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
5
-
-
41549131651
-
Cancer mortality in the European Union, 1970-2003, with a joinpoint analysis
-
PMID: 18281267
-
Bosetti C, Bertuccio P, Levi F, Lucchini F, Negri E, La Vecchia C. Cancer mortality in the European Union, 1970-2003, with a joinpoint analysis. Ann Oncol 2008; 19: 631-640 [PMID: 18281267 DOI: 10.1093/annonc/mdm597]
-
(2008)
Ann Oncol
, vol.19
, pp. 631-640
-
-
Bosetti, C.1
Bertuccio, P.2
Levi, F.3
Lucchini, F.4
Negri, E.5
La Vecchia, C.6
-
6
-
-
56749148631
-
Cancer mortality in Italy, 1970-2002
-
PMID: 19112936
-
Malvezzi M, Bosetti C, Negri E, La Vecchia C, Decarli A. Cancer mortality in Italy, 1970-2002. Tumori 2008; 94: 640-657 [PMID: 19112936]
-
(2008)
Tumori
, vol.94
, pp. 640-657
-
-
Malvezzi, M.1
Bosetti, C.2
Negri, E.3
La Vecchia, C.4
Decarli, A.5
-
7
-
-
0037570623
-
S-1 in gastric cancer: A comprehensive review
-
PMID: 12775012
-
Maehara Y. S-1 in gastric cancer: a comprehensive review. Gastric Cancer 2003; 6 Suppl 1: 2-8 [PMID: 12775012 DOI: 10.1007/s10120-003-0232-9]
-
(2003)
Gastric Cancer
, vol.6
, pp. 2-8
-
-
Maehara, Y.1
-
8
-
-
35748946650
-
Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine
-
PMID: 17978289
-
Sakuramoto S, Sasako M, Yamaguchi T, Kinoshita T, Fujii M, Nashimoto A, Furukawa H, Nakajima T, Ohashi Y, Imamura H, Higashino M, Yamamura Y, Kurita A, Arai K. Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med 2007; 357: 1810-1820 [PMID: 17978289 DOI: 10.1056/NEJMoa072252]
-
(2007)
N Engl J Med
, vol.357
, pp. 1810-1820
-
-
Sakuramoto, S.1
Sasako, M.2
Yamaguchi, T.3
Kinoshita, T.4
Fujii, M.5
Nashimoto, A.6
Furukawa, H.7
Nakajima, T.8
Ohashi, Y.9
Imamura, H.10
Higashino, M.11
Yamamura, Y.12
Kurita, A.13
Arai, K.14
-
9
-
-
55249096993
-
Phase II study of weekly paclitaxel by one-hour infusion for advanced gastric cancer
-
PMID: 18958560
-
Emi Y, Yamamoto M, Takahashi I, Orita H, Kakeji Y, Kohnoe S, Maehara Y. Phase II study of weekly paclitaxel by one-hour infusion for advanced gastric cancer. Surg Today 2008; 38: 1013-1020 [PMID: 18958560 DOI: 10.1007/s00595-008-3769-8]
-
(2008)
Surg Today
, vol.38
, pp. 1013-1020
-
-
Emi, Y.1
Yamamoto, M.2
Takahashi, I.3
Orita, H.4
Kakeji, Y.5
Kohnoe, S.6
Maehara, Y.7
-
10
-
-
73449121065
-
Docetaxel: Its role in current and future treatments for advanced gastric cancer
-
PMID: 19890692
-
Nishiyama M, Wada S. Docetaxel: its role in current and future treatments for advanced gastric cancer. Gastric Cancer 2009; 12: 132-141 [PMID: 19890692 DOI: 10.1007/s10120-009-0521-z]
-
(2009)
Gastric Cancer
, vol.12
, pp. 132-141
-
-
Nishiyama, M.1
Wada, S.2
-
11
-
-
0037687787
-
The role of chemotherapy in the current treatment of gastric cancer
-
PMID: 12772882
-
Van Cutsem E, Haller D, Ohtsu A. The role of chemotherapy in the current treatment of gastric cancer. Gastric Cancer 2002; 5 Suppl 1: 17-22 [PMID: 12772882 DOI: 10.1007/s10120-002-0219-y]
-
(2002)
Gastric Cancer
, vol.5
, pp. 17-22
-
-
Van Cutsem, E.1
Haller, D.2
Ohtsu, A.3
-
12
-
-
40749153540
-
S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial
-
PMID: 18282805
-
Koizumi W, Narahara H, Hara T, Takagane A, Akiya T, Takagi M, Miyashita K, Nishizaki T, Kobayashi O, Takiyama W, Toh Y, Nagaie T, Takagi S, Yamamura Y, Yanaoka K, Orita H, Takeuchi M. S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial. Lancet Oncol 2008; 9: 215-221 [PMID: 18282805 DOI: 10.1016/S1470-2045(08)70035-4]
-
(2008)
Lancet Oncol
, vol.9
, pp. 215-221
-
-
Koizumi, W.1
Narahara, H.2
Hara, T.3
Takagane, A.4
Akiya, T.5
Takagi, M.6
Miyashita, K.7
Nishizaki, T.8
Kobayashi, O.9
Takiyama, W.10
Toh, Y.11
Nagaie, T.12
Takagi, S.13
Yamamura, Y.14
Yanaoka, K.15
Orita, H.16
Takeuchi, M.17
-
13
-
-
75149136556
-
Preoperative chemotherapy with S-1 and cisplatin for highly advanced gastric cancer
-
PMID: 20032421
-
Nashimoto A, Yabusaki H, Nakagawa S, Takii Y, Tsuchiya Y, Otsuo T. Preoperative chemotherapy with S-1 and cisplatin for highly advanced gastric cancer. Anticancer Res 2009; 29: 4689-4696 [PMID: 20032421]
-
(2009)
Anticancer Res
, vol.29
, pp. 4689-4696
-
-
Nashimoto, A.1
Yabusaki, H.2
Nakagawa, S.3
Takii, Y.4
Tsuchiya, Y.5
Otsuo, T.6
-
14
-
-
0034855942
-
Nuclear localization of EGF receptor and its potential new role as a transcription factor
-
PMID: 11533659
-
Lin SY, Makino K, Xia W, Matin A, Wen Y, Kwong KY, Bourguignon L, Hung MC. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol 2001; 3: 802-808 [PMID: 11533659 DOI: 10.1038/ncb0901-802]
-
(2001)
Nat Cell Biol
, vol.3
, pp. 802-808
-
-
Lin, S.Y.1
Makino, K.2
Xia, W.3
Matin, A.4
Wen, Y.5
Kwong, K.Y.6
Bourguignon, L.7
Hung, M.C.8
-
15
-
-
8444243682
-
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
-
PMID: 15534001
-
Williams CC, Allison JG, Vidal GA, Burow ME, Beckman BS, Marrero L, Jones FE. The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone. J Cell Biol 2004; 167: 469-478 [PMID: 15534001 DOI: 10.1083/jcb.200403155]
-
(2004)
J Cell Biol
, vol.167
, pp. 469-478
-
-
Williams, C.C.1
Allison, J.G.2
Vidal, G.A.3
Burow, M.E.4
Beckman, B.S.5
Marrero, L.6
Jones, F.E.7
-
16
-
-
77956292811
-
The role of HER2 in cancer therapy and targeted drug delivery
-
PMID: 20385184
-
Tai W, Mahato R, Cheng K. The role of HER2 in cancer therapy and targeted drug delivery. J Control Release 2010; 146: 264-275 [PMID: 20385184 DOI: 10.1016/j.jconrel.2010.04.009]
-
(2010)
J Control Release
, vol.146
, pp. 264-275
-
-
Tai, W.1
Mahato, R.2
Cheng, K.3
-
17
-
-
77956895978
-
HER2 diagnostics in gastric cancer-guideline validation and development of standardized immunohistochemical testing
-
PMID: 20665045
-
Rüschoff J, Dietel M, Baretton G, Arbogast S, Walch A, Monges G, Chenard MP, Penault-Llorca F, Nagelmeier I, Schlake W, Höfler H, Kreipe HH. HER2 diagnostics in gastric cancer-guideline validation and development of standardized immunohistochemical testing. Virchows Arch 2010; 457: 299-307 [PMID: 20665045 DOI: 10.1007/s00428-010-0952-2]
-
(2010)
Virchows Arch
, vol.457
, pp. 299-307
-
-
Rüschoff, J.1
Dietel, M.2
Baretton, G.3
Arbogast, S.4
Walch, A.5
Monges, G.6
Chenard, M.P.7
Penault-Llorca, F.8
Nagelmeier, I.9
Schlake, W.10
Höfler, H.11
Kreipe, H.H.12
-
18
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
PMID: 2999974
-
Coussens L, Yang-Feng TL, Liao YC, Chen E, Gray A, Mc-Grath J, Seeburg PH, Libermann TA, Schlessinger J, Francke U. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985; 230: 1132-1139 [PMID: 2999974 DOI: 10.1126/science.2999974]
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
Chen, E.4
Gray, A.5
Mc-Grath, J.6
Seeburg, P.H.7
Libermann, T.A.8
Schlessinger, J.9
Francke, U.10
-
19
-
-
0022647432
-
The product of the human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity
-
PMID: 3012781
-
Akiyama T, Sudo C, Ogawara H, Toyoshima K, Yamamoto T. The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity. Science 1986; 232: 1644-1646 [PMID: 3012781 DOI: 10.1126/science.3012781]
-
(1986)
Science
, vol.232
, pp. 1644-1646
-
-
Akiyama, T.1
Sudo, C.2
Ogawara, H.3
Toyoshima, K.4
Yamamoto, T.5
-
20
-
-
0024651788
-
Localization of the human erbB-2 gene on normal and rearranged chromosomes 17 to bands q12-21.32
-
PMID: 2565881
-
Popescu NC, King CR, Kraus MH. Localization of the human erbB-2 gene on normal and rearranged chromosomes 17 to bands q12-21.32. Genomics 1989; 4: 362-366 [PMID: 2565881 DOI: 10.1016/0888-7543(89)90343-1]
-
(1989)
Genomics
, vol.4
, pp. 362-366
-
-
Popescu, N.C.1
King, C.R.2
Kraus, M.H.3
-
21
-
-
20044372721
-
Amplification of HER-2 in gastric carcinoma: Association with Topoisomerase IIalpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab
-
PMID: 15668283
-
Tanner M, Hollmén M, Junttila TT, Kapanen AI, Tommola S, Soini Y, Helin H, Salo J, Joensuu H, Sihvo E, Elenius K, Isola J. Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIalpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab. Ann Oncol 2005; 16: 273-278 [PMID: 15668283 DOI: 10.1093/annonc/mdi064]
-
(2005)
Ann Oncol
, vol.16
, pp. 273-278
-
-
Tanner, M.1
Hollmén, M.2
Junttila, T.T.3
Kapanen, A.I.4
Tommola, S.5
Soini, Y.6
Helin, H.7
Salo, J.8
Joensuu, H.9
Sihvo, E.10
Elenius, K.11
Isola, J.12
-
22
-
-
0027283498
-
Stability of HER-2/neu expression over time and at multiple metastatic sites
-
PMID: 8101229
-
Niehans GA, Singleton TP, Dykoski D, Kiang DT. Stability of HER-2/neu expression over time and at multiple metastatic sites. J Natl Cancer Inst 1993; 85: 1230-1235 [PMID: 8101229 DOI: 10.1093/jnci/85.15.1230]
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1230-1235
-
-
Niehans, G.A.1
Singleton, T.P.2
Dykoski, D.3
Kiang, D.T.4
-
23
-
-
79955928823
-
Clinicopathologic significance of HER-2/neu protein expression and gene amplification in gastric carcinoma
-
PMID: 21472111
-
Yan SY, Hu Y, Fan JG, Tao GQ, Lu YM, Cai X, Yu BH, Du YQ. Clinicopathologic significance of HER-2/neu protein expression and gene amplification in gastric carcinoma. World J Gastroenterol 2011; 17: 1501-1506 [PMID: 21472111 DOI: 10.3748/wjg.v17.i11.1501]
-
(2011)
World J Gastroenterol
, vol.17
, pp. 1501-1506
-
-
Yan, S.Y.1
Hu, Y.2
Fan, J.G.3
Tao, G.Q.4
Lu, Y.M.5
Cai, X.6
Yu, B.H.7
Du, Y.Q.8
-
24
-
-
78650783838
-
HER2 testing in gastric cancer
-
PMID: 21169738
-
Albarello L, Pecciarini L, Doglioni C. HER2 testing in gastric cancer. Adv Anat Pathol 2011; 18: 53-59 [PMID: 21169738 DOI: 10.1097/PAP.0b013e3182026d72]
-
(2011)
Adv Anat Pathol
, vol.18
, pp. 53-59
-
-
Albarello, L.1
Pecciarini, L.2
Doglioni, C.3
-
25
-
-
50849123421
-
HER2 in gastric cancer: A new prognostic factor and a novel therapeutic target
-
PMID: 18441328
-
Gravalos C, Jimeno A. HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target. Ann Oncol 2008; 19: 1523-1529 [PMID: 18441328 DOI: 10.1093/annonc/mdn169]
-
(2008)
Ann Oncol
, vol.19
, pp. 1523-1529
-
-
Gravalos, C.1
Jimeno, A.2
-
26
-
-
70450209516
-
Pathological features of advanced gastric cancer (GC): Relationship to human epidermal growth factor receptor 2 (HER2) positivity in the global screening programme of the ToGA trial
-
Bang Y, Chung H, Xu J, Lordick F, Sawaki A, Lipatov O, See C, Rueschoff J, Cutsem EV. Pathological features of advanced gastric cancer (GC): Relationship to human epidermal growth factor receptor 2 (HER2) positivity in the global screening programme of the ToGA trial. J Clin Oncol 2009; 27: 4556
-
(2009)
J Clin Oncol
, vol.27
, pp. 4556
-
-
Bang, Y.1
Chung, H.2
Xu, J.3
Lordick, F.4
Sawaki, A.5
Lipatov, O.6
See, C.7
Rueschoff, J.8
Cutsem, E.V.9
-
28
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
PMID: 9403702
-
Petit AM, Rak J, Hung MC, Rockwell P, Goldstein N, Fendly B, Kerbel RS. Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors. Am J Pathol 1997; 151: 1523-1530 [PMID: 9403702]
-
(1997)
Am J Pathol
, vol.151
, pp. 1523-1530
-
-
Petit, A.M.1
Rak, J.2
Hung, M.C.3
Rockwell, P.4
Goldstein, N.5
Fendly, B.6
Kerbel, R.S.7
-
29
-
-
67649472398
-
Novel anticancer targets: Revisiting ERBB2 and discovering ERBB3
-
PMID: 19536107
-
Baselga J, Swain SM. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer 2009; 9: 463-475 [PMID: 19536107 DOI: 10.1038/nrc2656]
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 463-475
-
-
Baselga, J.1
Swain, S.M.2
-
30
-
-
33947320114
-
Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models
-
PMID: 17031648
-
Fujimoto-Ouchi K, Sekiguchi F, Yasuno H, Moriya Y, Mori K, Tanaka Y. Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models. Cancer Chemother Pharmacol 2007; 59: 795-805 [PMID: 17031648 DOI: 10.1007/s00280-006-0337-z]
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 795-805
-
-
Fujimoto-Ouchi, K.1
Sekiguchi, F.2
Yasuno, H.3
Moriya, Y.4
Mori, K.5
Tanaka, Y.6
-
31
-
-
24344489058
-
Suppression of tumor growth in human gastric cancer with HER2 overexpression by an anti-HER2 antibody in a murine model
-
PMID: 16077916
-
Matsui Y, Inomata M, Tojigamori M, Sonoda K, Shiraishi N, Kitano S. Suppression of tumor growth in human gastric cancer with HER2 overexpression by an anti-HER2 antibody in a murine model. Int J Oncol 2005; 27: 681-685 [PMID: 16077916]
-
(2005)
Int J Oncol
, vol.27
, pp. 681-685
-
-
Matsui, Y.1
Inomata, M.2
Tojigamori, M.3
Sonoda, K.4
Shiraishi, N.5
Kitano, S.6
-
32
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
PMID: 20728210
-
Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, Aprile G, Kulikov E, Hill J, Lehle M, Rüschoff J, Kang YK. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010; 376: 687-697 [PMID: 20728210 DOI: 10.1016/S0140-6736(10)61121-X]
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
Chung, H.C.4
Shen, L.5
Sawaki, A.6
Lordick, F.7
Ohtsu, A.8
Omuro, Y.9
Satoh, T.10
Aprile, G.11
Kulikov, E.12
Hill, J.13
Lehle, M.14
Rüschoff, J.15
Kang, Y.K.16
-
33
-
-
78649724338
-
Human epidermal growth factor receptor 2 (HER2) in gastric cancer: A new therapeutic target. Cancer Treat Rev
-
PMID: 21129604
-
De Vita F, Giuliani F, Silvestris N, Catalano G, Ciardiello F, Orditura M. Human epidermal growth factor receptor 2 (HER2) in gastric cancer: a new therapeutic target. Cancer Treat Rev 2010; 36 Suppl 3: S11-S15 [PMID: 21129604 DOI: 10.1016/S0305-7372(10)70014-1]
-
(2010)
36 Suppl
, vol.3
, pp. S11-S15
-
-
De Vita, F.1
Giuliani, F.2
Silvestris, N.3
Catalano, G.4
Ciardiello, F.5
Orditura, M.6
-
34
-
-
79954475621
-
Her-2/neu testing and therapy in gastroesophageal adenocarcinoma
-
PMID: 21188213
-
Moelans CB, van Diest PJ, Milne AN, Offerhaus GJ. Her-2/neu testing and therapy in gastroesophageal adenocarcinoma. Patholog Res Int 2011; 2011: 674182 [PMID: 21188213 DOI: 10.4061/2011/674182]
-
(2011)
Patholog Res Int
, vol.2011
, pp. 674182
-
-
Moelans, C.B.1
Van Diest, P.J.2
Milne, A.N.3
Offerhaus, G.J.4
-
35
-
-
77950859162
-
Gastric cancer: Trastuzumab trial results spur search for other targets
-
PMID: 19755679
-
Hede K. Gastric cancer: trastuzumab trial results spur search for other targets. J Natl Cancer Inst 2009; 101: 1306-1307 [PMID: 19755679 DOI: 10.1093/jnci/djp341]
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1306-1307
-
-
Hede, K.1
-
36
-
-
0032586731
-
Prognostic value of Laurén classification and c-erbB-2 oncogene overexpression in adenocarcinoma of the esophagus and gastroesophageal junction
-
PMID: 10340889
-
Polkowski W, van Sandick JW, Offerhaus GJ, ten Kate FJ, Mulder J, Obertop H, van Lanschot JJ. Prognostic value of Laurén classification and c-erbB-2 oncogene overexpression in adenocarcinoma of the esophagus and gastroesophageal junction. Ann Surg Oncol 1999; 6: 290-297 [PMID: 10340889 DOI: 10.1007/s10434-999-0290-2]
-
(1999)
Ann Surg Oncol
, vol.6
, pp. 290-297
-
-
Polkowski, W.1
Van Sandick, J.W.2
Offerhaus, G.J.3
Ten Kate, F.J.4
Mulder, J.5
Obertop, H.6
Van Lanschot, J.J.7
-
37
-
-
78651323217
-
Genomic and epigenetic profiles of gastric cancer: Potential diagnostic and therapeutic applications
-
PMID: 21191688
-
Yamashita K, Sakuramoto S, Watanabe M. Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications. Surg Today 2011; 41: 24-38 [PMID: 21191688 DOI: 10.1007/s00595-010-4370-5]
-
(2011)
Surg Today
, vol.41
, pp. 24-38
-
-
Yamashita, K.1
Sakuramoto, S.2
Watanabe, M.3
-
38
-
-
77954217471
-
Trastuzumab in gastric cancer
-
PMID: 20542421
-
Okines AF, Cunningham D. Trastuzumab in gastric cancer. Eur J Cancer 2010; 46: 1949-1959 [PMID: 20542421 DOI: 10.1016/j.ejca.2010.05.003]
-
(2010)
Eur J Cancer
, vol.46
, pp. 1949-1959
-
-
Okines, A.F.1
Cunningham, D.2
-
39
-
-
71249128928
-
Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: A randomised phase 3 study
-
PMID: 19818685
-
Boku N, Yamamoto S, Fukuda H, Shirao K, Doi T, Sawaki A, Koizumi W, Saito H, Yamaguchi K, Takiuchi H, Nasu J, Ohtsu A. Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study. Lancet Oncol 2009; 10: 1063-1069 [PMID: 19818685 DOI: 10.1016/S1470-2045(09)70259-1]
-
(2009)
Lancet Oncol
, vol.10
, pp. 1063-1069
-
-
Boku, N.1
Yamamoto, S.2
Fukuda, H.3
Shirao, K.4
Doi, T.5
Sawaki, A.6
Koizumi, W.7
Saito, H.8
Yamaguchi, K.9
Takiuchi, H.10
Nasu, J.11
Ohtsu, A.12
-
40
-
-
79959380640
-
New Japanese classifications and treatment guidelines for gastric cancer: Revision concepts and major revised points
-
PMID: 21573921
-
Sano T, Aiko T. New Japanese classifications and treatment guidelines for gastric cancer: revision concepts and major revised points. Gastric Cancer 2011; 14: 97-100 [PMID: 21573921 DOI: 10.1007/s10120-011-0040-6]
-
(2011)
Gastric Cancer
, vol.14
, pp. 97-100
-
-
Sano, T.1
Aiko, T.2
-
41
-
-
84919398686
-
Efficacy of S-1 plus cisplatin combination chemotherapy in patients with HER2-positive advanced gastric cancer
-
Nov 12; Epub ahead of print [PMID: 24218279]
-
Honma Y, Shimada Y, Takashima A, Iwasa S, Kato K, Hamaguchi T, Yamada Y, Taniguchi H, Sekine S, Kushima R. Efficacy of S-1 plus cisplatin combination chemotherapy in patients with HER2-positive advanced gastric cancer. Int J Clin Oncol 2013 Nov 12; Epub ahead of print [PMID: 24218279]
-
(2013)
Int J Clin Oncol
-
-
Honma, Y.1
Shimada, Y.2
Takashima, A.3
Iwasa, S.4
Kato, K.5
Hamaguchi, T.6
Yamada, Y.7
Taniguchi, H.8
Sekine, S.9
Kushima, R.10
-
42
-
-
78650874372
-
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
-
PMID: 12748309
-
Abrams TJ, Lee LB, Murray LJ, Pryer NK, Cherrington JM. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003; 2: 471-478 [PMID: 12748309]
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
Pryer, N.K.4
Cherrington, J.M.5
-
43
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
PMID: 12538485
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, Schreck RE, Abrams TJ, Ngai TJ, Lee LB, Murray LJ, Carver J, Chan E, Moss KG, Haznedar JO, Sukbuntherng J, Blake RA, Sun L, Tang C, Miller T, Shirazian S, McMahon G, Cherrington JM. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003; 9: 327-337 [PMID: 12538485]
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
Chan, E.13
Moss, K.G.14
Haznedar, J.O.15
Sukbuntherng, J.16
Blake, R.A.17
Sun, L.18
Tang, C.19
Miller, T.20
Shirazian, S.21
McMahon, G.22
Cherrington, J.M.23
more..
-
44
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
PMID: 12531805
-
O'Farrell AM, Abrams TJ, Yuen HA, Ngai TJ, Louie SG, Yee KW, Wong LM, Hong W, Lee LB, Town A, Smolich BD, Manning WC, Murray LJ, Heinrich MC, Cherrington JM. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003; 101: 3597-3605 [PMID: 12531805 DOI: 10.1182/blood-2002-07-2307]
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
Smolich, B.D.11
Manning, W.C.12
Murray, L.J.13
Heinrich, M.C.14
Cherrington, J.M.15
-
45
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
-
PMID: 17046465
-
Demetri GD, van Oosterom AT, Garrett CR, Blackstein ME, Shah MH, Verweij J, McArthur G, Judson IR, Heinrich MC, Morgan JA, Desai J, Fletcher CD, George S, Bello CL, Huang X, Baum CM, Casali PG. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 2006; 368: 1329-1338 [PMID: 17046465 DOI: 10.1016/S0140-6736(06)69446-4]
-
(2006)
Lancet
, vol.368
, pp. 1329-1338
-
-
Demetri, G.D.1
Van Oosterom, A.T.2
Garrett, C.R.3
Blackstein, M.E.4
Shah, M.H.5
Verweij, J.6
McArthur, G.7
Judson, I.R.8
Heinrich, M.C.9
Morgan, J.A.10
Desai, J.11
Fletcher, C.D.12
George, S.13
Bello, C.L.14
Huang, X.15
Baum, C.M.16
Casali, P.G.17
-
46
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
PMID: 17215529
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, Chen I, Bycott PW, Baum CM, Figlin RA. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007; 356: 115-124 [PMID: 17215529 DOI: 10.1056/NEJMoa065044]
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
47
-
-
79958803154
-
An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer
-
PMID: 21561763
-
Moehler M, Mueller A, Hartmann JT, Ebert MP, Al-Batran SE, Reimer P, Weihrauch M, Lordick F, Trarbach T, Biesterfeld S, Kabisch M, Wachtlin D, Galle PR. An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer. Eur J Cancer 2011; 47: 1511-1520 [PMID: 21561763 DOI: 10.1016/j.ejca.2011.04.006]
-
(2011)
Eur J Cancer
, vol.47
, pp. 1511-1520
-
-
Moehler, M.1
Mueller, A.2
Hartmann, J.T.3
Ebert, M.P.4
Al-Batran, S.E.5
Reimer, P.6
Weihrauch, M.7
Lordick, F.8
Trarbach, T.9
Biesterfeld, S.10
Kabisch, M.11
Wachtlin, D.12
Galle, P.R.13
-
48
-
-
82955241985
-
Phase II study of sunitinib as second-line treatment for advanced gastric cancer
-
PMID: 20461441
-
Bang YJ, Kang YK, Kang WK, Boku N, Chung HC, Chen JS, Doi T, Sun Y, Shen L, Qin S, Ng WT, Tursi JM, Lechuga MJ, Lu DR, Ruiz-Garcia A, Sobrero A. Phase II study of sunitinib as second-line treatment for advanced gastric cancer. Invest New Drugs 2011; 29: 1449-1458 [PMID: 20461441 DOI: 10.1007/s10637-010-9438-y]
-
(2011)
Invest New Drugs
, vol.29
, pp. 1449-1458
-
-
Bang, Y.J.1
Kang, Y.K.2
Kang, W.K.3
Boku, N.4
Chung, H.C.5
Chen, J.S.6
Doi, T.7
Sun, Y.8
Shen, L.9
Qin, S.10
Ng, W.T.11
Tursi, J.M.12
Lechuga, M.J.13
Lu, D.R.14
Ruiz-Garcia, A.15
Sobrero, A.16
-
49
-
-
84860234330
-
Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum
-
PMID: 22460270
-
Yi JH, Lee J, Lee J, Park SH, Park JO, Yim DS, Park YS, Lim HY, Kang WK. Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum. Br J Cancer 2012; 106: 1469-1474 [PMID: 22460270 DOI: 10.1038/bjc.2012.100]
-
(2012)
Br J Cancer
, vol.106
, pp. 1469-1474
-
-
Yi, J.H.1
Lee, J.2
Lee, J.3
Park, S.H.4
Park, J.O.5
Yim, D.S.6
Park, Y.S.7
Lim, H.Y.8
Kang, W.K.9
-
50
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
PMID: 6823562
-
Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983; 219: 983-985 [PMID: 6823562]
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
51
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
PMID: 2735925
-
Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989; 161: 851-858 [PMID: 2735925 DOI: 10.1016/0006-291X(89)92678-8]
-
(1989)
Biochem Biophys Res Commun
, vol.161
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.J.2
-
52
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
PMID: 7538264
-
Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995; 146: 1029-1039 [PMID: 7538264]
-
(1995)
Am J Pathol
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
53
-
-
0026321129
-
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
-
PMID: 1755866
-
Pepper MS, Ferrara N, Orci L, Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 1991; 181: 902-906 [PMID: 1755866 DOI: 10.1016/0006-291X(91)91276-I]
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 902-906
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
Montesano, R.4
-
54
-
-
0026446859
-
Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells
-
PMID: 1447317
-
Unemori EN, Ferrara N, Bauer EA, Amento EP. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol 1992; 153: 557-562 [PMID: 1447317]
-
(1992)
J Cell Physiol
, vol.153
, pp. 557-562
-
-
Unemori, E.N.1
Ferrara, N.2
Bauer, E.A.3
Amento, E.P.4
-
55
-
-
0033231069
-
Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
-
PMID: 10554007
-
Shaheen RM, Davis DW, Liu W, Zebrowski BK, Wilson MR, Bucana CD, McConkey DJ, McMahon G, Ellis LM. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res 1999; 59: 5412-5416 [PMID: 10554007]
-
(1999)
Cancer Res
, vol.59
, pp. 5412-5416
-
-
Shaheen, R.M.1
Davis, D.W.2
Liu, W.3
Zebrowski, B.K.4
Wilson, M.R.5
Bucana, C.D.6
McConkey, D.J.7
McMahon, G.8
Ellis, L.M.9
-
56
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
-
PMID: 9804796
-
Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 1998; 273: 30336-30343 [PMID: 9804796 DOI: 10.1074/jbc.273.46.30336]
-
(1998)
J Biol Chem
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Yan, M.4
Keyt, B.A.5
Dixit, V.6
Ferrara, N.7
-
57
-
-
0034883882
-
Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1
-
PMID: 11501971
-
Lissoni P, Malugani F, Bonfanti A, Bucovec R, Secondino S, Brivio F, Ferrari-Bravo A, Ferrante R, Vigoré L, Rovelli F, Mandalà M, Viviani S, Fumagalli L, Gardani GS. Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1. J Biol Regul Homeost Agents 2001; 15: 140-144 [PMID: 11501971]
-
(2001)
J Biol Regul Homeost Agents
, vol.15
, pp. 140-144
-
-
Lissoni, P.1
Malugani, F.2
Bonfanti, A.3
Bucovec, R.4
Secondino, S.5
Brivio, F.6
Ferrari-Bravo, A.7
Ferrante, R.8
Vigoré, L.9
Rovelli, F.10
Mandalà, M.11
Viviani, S.12
Fumagalli, L.13
Gardani, G.S.14
-
58
-
-
58149190795
-
Pathways mediating resistance to vascular endothelial growth factor-targeted therapy
-
PMID: 18927275
-
Ellis LM, Hicklin DJ. Pathways mediating resistance to vascular endothelial growth factor-targeted therapy. Clin Cancer Res 2008; 14: 6371-6375 [PMID: 18927275 DOI: 10.1158/1078-0432.CCR-07-5287]
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6371-6375
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
59
-
-
84875544045
-
Significance of preoperative tissue levels of vascular-endothelial cadherin, liver-intestine cadherin and vascular endothelial growth factor in gastric cancer
-
PMID: 23089909
-
Ryu KH, Shim KN, Jung SA, Yoo K, Joo YH, Lee JH. Significance of preoperative tissue levels of vascular-endothelial cadherin, liver-intestine cadherin and vascular endothelial growth factor in gastric cancer. Korean J Gastroenterol 2012; 60: 229-241 [PMID: 23089909 DOI: 10.4166/kjg.2012.60.4.229]
-
(2012)
Korean J Gastroenterol
, vol.60
, pp. 229-241
-
-
Ryu, K.H.1
Shim, K.N.2
Jung, S.A.3
Yoo, K.4
Joo, Y.H.5
Lee, J.H.6
-
60
-
-
84873602673
-
Prognostic value of vascular endothelial growth factor expression in resected gastric cancer
-
PMID: 22994715
-
Liu L, Ma XL, Xiao ZL, Li M, Cheng SH, Wei YQ. Prognostic value of vascular endothelial growth factor expression in resected gastric cancer. Asian Pac J Cancer Prev 2012; 13: 3089-3097 [PMID: 22994715 DOI: 10.7314/APJCP.2012.13.7.3089]
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 3089-3097
-
-
Liu, L.1
Ma, X.L.2
Xiao, Z.L.3
Li, M.4
Cheng, S.H.5
Wei, Y.Q.6
-
61
-
-
23844522021
-
VEGF significance in peritoneal recurrence from gastric cancer
-
PMID: 16086118
-
Aoyagi K, Kouhuji K, Yano S, Miyagi M, Imaizumi T, Takeda J, Shirouzu K. VEGF significance in peritoneal recurrence from gastric cancer. Gastric Cancer 2005; 8: 155-163 [PMID: 16086118 DOI: 10.1007/s10120-005-0329-4]
-
(2005)
Gastric Cancer
, vol.8
, pp. 155-163
-
-
Aoyagi, K.1
Kouhuji, K.2
Yano, S.3
Miyagi, M.4
Imaizumi, T.5
Takeda, J.6
Shirouzu, K.7
-
62
-
-
84910017715
-
Molecular targeting therapy using bevacizumab for peritoneal metastasis from gastric cancer
-
PMID: 24701416
-
Aoyagi K, Kouhuji K, Miyagi M, Kizaki J, Isobe T, Hashimoto K, Shirouzu K. Molecular targeting therapy using bevacizumab for peritoneal metastasis from gastric cancer. World J Crit Care Med 2013; 2: 48-55 [PMID: 24701416 DOI: 10.5492/wjccm.v2.i4.48]
-
(2013)
World J Crit Care Med
, vol.2
, pp. 48-55
-
-
Aoyagi, K.1
Kouhuji, K.2
Miyagi, M.3
Kizaki, J.4
Isobe, T.5
Hashimoto, K.6
Shirouzu, K.7
-
63
-
-
33846629672
-
Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
-
PMID: 17114652
-
Shah MA, Ramanathan RK, Ilson DH, Levnor A, D'Adamo D, O'Reilly E, Tse A, Trocola R, Schwartz L, Capanu M, Schwartz GK, Kelsen DP. Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. J Clin Oncol 2006; 24: 5201-5206 [PMID: 17114652 DOI: 10.1200/JCO.2006.08.0887]
-
(2006)
J Clin Oncol
, vol.24
, pp. 5201-5206
-
-
Shah, M.A.1
Ramanathan, R.K.2
Ilson, D.H.3
Levnor, A.4
D'Adamo, D.5
O'Reilly, E.6
Tse, A.7
Trocola, R.8
Schwartz, L.9
Capanu, M.10
Schwartz, G.K.11
Kelsen, D.P.12
-
64
-
-
79952355358
-
Phase II study of modified docetaxel, cisplatin, and fluorouracil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma
-
PMID: 21189380
-
Shah MA, Jhawer M, Ilson DH, Lefkowitz RA, Robinson E, Capanu M, Kelsen DP. Phase II study of modified docetaxel, cisplatin, and fluorouracil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma. J Clin Oncol 2011; 29: 868-874 [PMID: 21189380 DOI: 10.1200/JCO.2010.32.0770]
-
(2011)
J Clin Oncol
, vol.29
, pp. 868-874
-
-
Shah, M.A.1
Jhawer, M.2
Ilson, D.H.3
Lefkowitz, R.A.4
Robinson, E.5
Capanu, M.6
Kelsen, D.P.7
-
65
-
-
80053573446
-
Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: A randomized, double-blind, placebo-controlled phase III study
-
PMID: 21844504
-
Ohtsu A, Shah MA, Van Cutsem E, Rha SY, Sawaki A, Park SR, Lim HY, Yamada Y, Wu J, Langer B, Starnawski M, Kang YK. Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a randomized, double-blind, placebo-controlled phase III study. J Clin Oncol 2011; 29: 3968-3976 [PMID: 21844504 DOI: 10.1200/JCO.2011.36.2236]
-
(2011)
J Clin Oncol
, vol.29
, pp. 3968-3976
-
-
Ohtsu, A.1
Shah, M.A.2
Van Cutsem, E.3
Rha, S.Y.4
Sawaki, A.5
Park, S.R.6
Lim, H.Y.7
Yamada, Y.8
Wu, J.9
Langer, B.10
Starnawski, M.11
Kang, Y.K.12
-
66
-
-
84910016914
-
Survival analysis by gastric cancer subtypes in AVAGAST phase III trial
-
Helwick C, editor. Proceedings of the 2012 Gastrointestinal Cancers Symposium: 19-21 January 2012; San Francisco
-
Shah MA. Survival analysis by gastric cancer subtypes in AVAGAST phase III trial. In: Helwick C, editor. Proceedings of the 2012 Gastrointestinal Cancers Symposium: 19-21 January 2012; San Francisco. The ASCO post 2012; 3: 6
-
(2012)
The ASCO Post
, vol.3
, pp. 6
-
-
Shah, M.A.1
-
67
-
-
34548071359
-
Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network
-
PMID: 17699871
-
Ritter CA, Perez-Torres M, Rinehart C, Guix M, Dugger T, Engelman JA, Arteaga CL. Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network. Clin Cancer Res 2007; 13: 4909-4919 [PMID: 17699871 DOI: 10.1158/1078-0432.CCR-07-0701]
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4909-4919
-
-
Ritter, C.A.1
Perez-Torres, M.2
Rinehart, C.3
Guix, M.4
Dugger, T.5
Engelman, J.A.6
Arteaga, C.L.7
-
68
-
-
77649162889
-
Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo
-
PMID: 20179222
-
Wainberg ZA, Anghel A, Desai AJ, Ayala R, Luo T, Safran B, Fejzo MS, Hecht JR, Slamon DJ, Finn RS. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res 2010; 16: 1509-1519 [PMID: 20179222 DOI: 10.1158/1078-0432.CCR-09-1112]
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1509-1519
-
-
Wainberg, Z.A.1
Anghel, A.2
Desai, A.J.3
Ayala, R.4
Luo, T.5
Safran, B.6
Fejzo, M.S.7
Hecht, J.R.8
Slamon, D.J.9
Finn, R.S.10
-
69
-
-
80054057131
-
Southwest Oncology Group study S0413: A phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer
-
PMID: 21415234
-
Iqbal S, Goldman B, Fenoglio-Preiser CM, Lenz HJ, Zhang W, Danenberg KD, Shibata SI, Blanke CD. Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer. Ann Oncol 2011; 22: 2610-2615 [PMID: 21415234 DOI: 10.1093/annonc/mdr021]
-
(2011)
Ann Oncol
, vol.22
, pp. 2610-2615
-
-
Iqbal, S.1
Goldman, B.2
Fenoglio-Preiser, C.M.3
Lenz, H.J.4
Zhang, W.5
Danenberg, K.D.6
Shibata, S.I.7
Blanke, C.D.8
-
70
-
-
84885603623
-
Personalizing therapies for gastric cancer: Molecular mechanisms and novel targeted therapies
-
PMID: 24151357
-
Luis M, Tavares A, Carvalho LS, Lara-Santos L, Araújo A, de Mello RA. Personalizing therapies for gastric cancer: molecular mechanisms and novel targeted therapies. World J Gastroenterol 2013; 19: 6383-6397 [PMID: 24151357 DOI: 10.3748/wjg.v19.i38.6383]
-
(2013)
World J Gastroenterol
, vol.19
, pp. 6383-6397
-
-
Luis, M.1
Tavares, A.2
Carvalho, L.S.3
Lara-Santos, L.4
Araújo, A.5
De Mello, R.A.6
-
71
-
-
84861184026
-
A global, multi-center phase II trial of lapatinib plus capecitabine in gastric cancer
-
Pishvaian M, Sakaeva D, Hsieh R. A global, multi-center phase II trial of lapatinib plus capecitabine in gastric cancer. J Clin Oncol 2011; 29 suppl 4: abstr 88
-
(2011)
J Clin Oncol
, vol.29
-
-
Pishvaian, M.1
Sakaeva, D.2
Hsieh, R.3
-
72
-
-
79952977646
-
Lapatinib capecitabine in advanced gastric cancer: An open-label phase II study of non ERBB2-targeted disease
-
Lenz H, Zhang J, Kemner AM, Kaneko T, Yang D, Franklin N, Iqbal S. Lapatinib capecitabine in advanced gastric cancer: An open-label phase II study of non ERBB2-targeted disease. Anall Oncol 2010; 21: S817
-
(2010)
Anall Oncol
, vol.21
, pp. S817
-
-
Lenz, H.1
Zhang, J.2
Kemner, A.M.3
Kaneko, T.4
Yang, D.5
Franklin, N.6
Iqbal, S.7
-
74
-
-
84872219004
-
Lapatinib monotherapy in recurrent upper gastrointestinal malignancy: Phase II efficacy and biomarker analyses. Proceedings of the Gastrointestinal Cancers Symposium
-
Hecht JR, Urba SG, Koehler M, Ellis C, Gagnon R, Kemner A. Lapatinib monotherapy in recurrent upper gastrointestinal malignancy: Phase II efficacy and biomarker analyses. Proceedings of the Gastrointestinal Cancers Symposium. ASCO GI 2008; 43a
-
(2008)
ASCO GI
, pp. 43a
-
-
Hecht, J.R.1
Urba, S.G.2
Koehler, M.3
Ellis, C.4
Gagnon, R.5
Kemner, A.6
-
76
-
-
79960081156
-
Interim safety analysis from TYTAN: A phase III Asian study of lapatinib in combination with paclitaxel as second-line therapy in gastric cancer
-
Satoh T, Bang Y, Wang J, Xu J, Chung HC, Yeh K, Chen J, Mukaiyama A, Yoshida P, Ohtsu A. Interim safety analysis from TYTAN: A phase III Asian study of lapatinib in combination with paclitaxel as second-line therapy in gastric cancer. J Clin Oncol 2010; 28: abstr4057
-
(2010)
J Clin Oncol
, vol.28
-
-
Satoh, T.1
Bang, Y.2
Wang, J.3
Xu, J.4
Chung, H.C.5
Yeh, K.6
Chen, J.7
Mukaiyama, A.8
Yoshida, P.9
Ohtsu, A.10
-
77
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
PMID: 15122205
-
Bjornsti MA, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev Cancer 2004; 4: 335-348 [PMID: 15122205 DOI: 10.1038/nrc1362]
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
78
-
-
0342858949
-
4E binding protein 1 expression is inversely correlated to the progression of gastrointestinal cancers
-
PMID: 10785360
-
Martín ME, Pérez MI, Redondo C, Alvarez MI, Salinas M, Fando JL. 4E binding protein 1 expression is inversely correlated to the progression of gastrointestinal cancers. Int J Biochem Cell Biol 2000; 32: 633-642 [PMID: 10785360 DOI: 10.1016/S1357-2725(00)00007-8]
-
(2000)
Int J Biochem Cell Biol
, vol.32
, pp. 633-642
-
-
Martín, M.E.1
Pérez, M.I.2
Redondo, C.3
Alvarez, M.I.4
Salinas, M.5
Fando, J.L.6
-
79
-
-
34548427415
-
The biology behind mTOR inhibition in sarcoma
-
PMID: 17766661
-
Wan X, Helman LJ. The biology behind mTOR inhibition in sarcoma. Oncologist 2007; 12: 1007-1018 [PMID: 17766661 DOI: 10.1634/theoncologist.12-8-1007]
-
(2007)
Oncologist
, vol.12
, pp. 1007-1018
-
-
Wan, X.1
Helman, L.J.2
-
80
-
-
52149087173
-
Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo
-
PMID: 18708754
-
Cejka D, Preusser M, Woehrer A, Sieghart W, Strommer S, Werzowa J, Fuereder T, Wacheck V. Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo. Cancer Biol Ther 2008; 7: 1377-1385 [PMID: 18708754 DOI: 10.4161/cbt.7.9.6416]
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1377-1385
-
-
Cejka, D.1
Preusser, M.2
Woehrer, A.3
Sieghart, W.4
Strommer, S.5
Werzowa, J.6
Fuereder, T.7
Wacheck, V.8
-
81
-
-
74949131430
-
Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors
-
PMID: 19783551
-
Okamoto I, Doi T, Ohtsu A, Miyazaki M, Tsuya A, Kurei K, Kobayashi K, Nakagawa K. Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors. Jpn J Clin Oncol 2010; 40: 17-23 [PMID: 19783551 DOI: 10.1093/jjco/hyp120]
-
(2010)
Jpn J Clin Oncol
, vol.40
, pp. 17-23
-
-
Okamoto, I.1
Doi, T.2
Ohtsu, A.3
Miyazaki, M.4
Tsuya, A.5
Kurei, K.6
Kobayashi, K.7
Nakagawa, K.8
-
82
-
-
77951635629
-
Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer
-
PMID: 20231677
-
Doi T, Muro K, Boku N, Yamada Y, Nishina T, Takiuchi H, Komatsu Y, Hamamoto Y, Ohno N, Fujita Y, Robson M, Ohtsu A. Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer. J Clin Oncol 2010; 28: 1904-1910 [PMID: 20231677 DOI: 10.1200/JCO.2009.26.2923]
-
(2010)
J Clin Oncol
, vol.28
, pp. 1904-1910
-
-
Doi, T.1
Muro, K.2
Boku, N.3
Yamada, Y.4
Nishina, T.5
Takiuchi, H.6
Komatsu, Y.7
Hamamoto, Y.8
Ohno, N.9
Fujita, Y.10
Robson, M.11
Ohtsu, A.12
-
84
-
-
34848887261
-
Review: Monoclonal antibodies to the vascular endothelial growth factor receptor-2 in cancer therapy
-
PMID: 17875787
-
Youssoufian H, Hicklin DJ, Rowinsky EK. Review: monoclonal antibodies to the vascular endothelial growth factor receptor-2 in cancer therapy. Clin Cancer Res 2007; 13: 5544s-5548s [PMID: 17875787 DOI: 10.1158/1078-0432.CCR-07-1107]
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5544s-5548s
-
-
Youssoufian, H.1
Hicklin, D.J.2
Rowinsky, E.K.3
-
85
-
-
0242353266
-
Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity
-
PMID: 12917408
-
Lu D, Shen J, Vil MD, Zhang H, Jimenez X, Bohlen P, Witte L, Zhu Z. Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity. J Biol Chem 2003; 278: 43496-43507 [PMID: 12917408 DOI: 10.1074/jbc.M307742200]
-
(2003)
J Biol Chem
, vol.278
, pp. 43496-43507
-
-
Lu, D.1
Shen, J.2
Vil, M.D.3
Zhang, H.4
Jimenez, X.5
Bohlen, P.6
Witte, L.7
Zhu, Z.8
-
86
-
-
0344839087
-
Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity
-
PMID: 12646950
-
Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig DL, Dias S, Kussie P, Koo H, Kim HJ, Lu D, Liu M, Tejada R, Friedrich M, Bohlen P, Witte L, Rafii S. Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity. Leukemia 2003; 17: 604-611 [PMID: 12646950 DOI: 10.1038/sj.leu.2402831]
-
(2003)
Leukemia
, vol.17
, pp. 604-611
-
-
Zhu, Z.1
Hattori, K.2
Zhang, H.3
Jimenez, X.4
Ludwig, D.L.5
Dias, S.6
Kussie, P.7
Koo, H.8
Kim, H.J.9
Lu, D.10
Liu, M.11
Tejada, R.12
Friedrich, M.13
Bohlen, P.14
Witte, L.15
Rafii, S.16
-
87
-
-
77649213706
-
Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2
-
PMID: 20048182
-
Spratlin JL, Cohen RB, Eadens M, Gore L, Camidge DR, Diab S, Leong S, O'Bryant C, Chow LQ, Serkova NJ, Meropol NJ, Lewis NL, Chiorean EG, Fox F, Youssoufian H, Rowinsky EK, Eckhardt SG. Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2. J Clin Oncol 2010; 28: 780-787 [PMID: 20048182 DOI: 10.1200/JCO.2009.23.7537]
-
(2010)
J Clin Oncol
, vol.28
, pp. 780-787
-
-
Spratlin, J.L.1
Cohen, R.B.2
Eadens, M.3
Gore, L.4
Camidge, D.R.5
Diab, S.6
Leong, S.7
O'Bryant, C.8
Chow, L.Q.9
Serkova, N.J.10
Meropol, N.J.11
Lewis, N.L.12
Chiorean, E.G.13
Fox, F.14
Youssoufian, H.15
Rowinsky, E.K.16
Eckhardt, S.G.17
-
88
-
-
84878078429
-
REGARD: A phase III, randomized, double-blind trial of ramucirumab and best supportive care (BSC) versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing combination therapy
-
Fuchs CS, Tomasek J, Cho JY. REGARD: a phase III, randomized, double-blind trial of ramucirumab and best supportive care (BSC) versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing combination therapy. J Clin Oncol 2012; 30 suppl 34: abstr LBA5
-
(2012)
J Clin Oncol
, vol.30
-
-
Fuchs, C.S.1
Tomasek, J.2
Cho, J.Y.3
-
89
-
-
0034799139
-
A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
-
PMID: 11595683
-
Ciardiello F, Tortora G. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin Cancer Res 2001; 7: 2958-2970 [PMID: 11595683]
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2958-2970
-
-
Ciardiello, F.1
Tortora, G.2
-
90
-
-
0028907863
-
Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer
-
PMID: 7889468
-
Tokunaga A, Onda M, Okuda T, Teramoto T, Fujita I, Mizutani T, Kiyama T, Yoshiyuki T, Nishi K, Matsukura N. Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer. Cancer 1995; 75: 1418-1425 [PMID: 7889468 DOI: 10.1002/1097-0142(19950315)75:6〈1418::AID-CNCR2820751505〉3.0.CO;2-Y]
-
(1995)
Cancer
, vol.75
, pp. 1418-1425
-
-
Tokunaga, A.1
Onda, M.2
Okuda, T.3
Teramoto, T.4
Fujita, I.5
Mizutani, T.6
Kiyama, T.7
Yoshiyuki, T.8
Nishi, K.9
Matsukura, N.10
-
91
-
-
0035174127
-
Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839
-
PMID: 11706397
-
Albanell J, Rojo F, Baselga J. Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839. Semin Oncol 2001; 28: 56-66 [PMID: 11706397 DOI: 10.1053/sonc.2001.28551]
-
(2001)
Semin Oncol
, vol.28
, pp. 56-66
-
-
Albanell, J.1
Rojo, F.2
Baselga, J.3
-
92
-
-
0037106273
-
Targeting the epidermal growth factor receptor for cancer therapy
-
PMID: 12235219
-
Mendelsohn J . Targeting the epidermal growth factor receptor for cancer therapy. J Clin Oncol 2002; 20: 1S-13S [PMID: 12235219]
-
(2002)
J Clin Oncol
, vol.20
, pp. 1S-13S
-
-
Mendelsohn, J.1
-
93
-
-
0242610317
-
Expression of epidermal growth factor receptor in gastric carcinomas
-
PMID: 15017643
-
Takehana T, Kunitomo K, Suzuki S, Kono K, Fujii H, Matsumoto Y, Ooi A. Expression of epidermal growth factor receptor in gastric carcinomas. Clin Gastroenterol Hepatol 2003; 1: 438-445 [PMID: 15017643 DOI: 10.1016/S1542-3565(03)00219-2]
-
(2003)
Clin Gastroenterol Hepatol
, vol.1
, pp. 438-445
-
-
Takehana, T.1
Kunitomo, K.2
Suzuki, S.3
Kono, K.4
Fujii, H.5
Matsumoto, Y.6
Ooi, A.7
-
94
-
-
33847663871
-
Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
-
PMID: 17164226
-
Pinto C, Di Fabio F, Siena S, Cascinu S, Rojas Llimpe FL, Ceccarelli C, Mutri V, Giannetta L, Giaquinta S, Funaioli C, Berardi R, Longobardi C, Piana E, Martoni AA. Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study). Ann Oncol 2007; 18: 510-517 [PMID: 17164226 DOI: 10.1093/annonc/mdl459]
-
(2007)
Ann Oncol
, vol.18
, pp. 510-517
-
-
Pinto, C.1
Di Fabio, F.2
Siena, S.3
Cascinu, S.4
Rojas Llimpe, F.L.5
Ceccarelli, C.6
Mutri, V.7
Giannetta, L.8
Giaquinta, S.9
Funaioli, C.10
Berardi, R.11
Longobardi, C.12
Piana, E.13
Martoni, A.A.14
-
95
-
-
69949127786
-
Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy
-
PMID: 19737224
-
Martinelli E, De Palma R, Orditura M, De Vita F, Ciardiello F. Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy. Clin Exp Immunol 2009; 158: 1-9 [PMID: 19737224 DOI: 10.1111/j.1365-2249.2009.03992.x]
-
(2009)
Clin Exp Immunol
, vol.158
, pp. 1-9
-
-
Martinelli, E.1
De Palma, R.2
Orditura, M.3
De Vita, F.4
Ciardiello, F.5
-
96
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
PMID: 18337605
-
Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 2008; 358: 1160-1174 [PMID: 18337605 DOI: 10.1056/NEJMra0707704]
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
97
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
PMID: 19339720
-
Van Cutsem E, Köhne CH, Hitre E, Zaluski J, Chang Chien CR, Makhson A, D'Haens G, Pintér T, Lim R, Bodoky G, Roh JK, Folprecht G, Ruff P, Stroh C, Tejpar S, Schlichting M, Nippgen J, Rougier P. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009; 360: 1408-1417 [PMID: 19339720 DOI: 10.1056/NEJMoa0805019]
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
Zaluski, J.4
Chang Chien, C.R.5
Makhson, A.6
D'Haens, G.7
Pintér, T.8
Lim, R.9
Bodoky, G.10
Roh, J.K.11
Folprecht, G.12
Ruff, P.13
Stroh, C.14
Tejpar, S.15
Schlichting, M.16
Nippgen, J.17
Rougier, P.18
-
98
-
-
70349937924
-
Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study)
-
PMID: 19773760
-
Pinto C, Di Fabio F, Barone C, Siena S, Falcone A, Cascinu S, Rojas Llimpe FL, Stella G, Schinzari G, Artale S, Mutri V, Giaquinta S, Giannetta L, Bardelli A, Martoni AA. Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study). Br J Cancer 2009; 101: 1261-1268 [PMID: 19773760 DOI: 10.1038/sj.bjc.6605319]
-
(2009)
Br J Cancer
, vol.101
, pp. 1261-1268
-
-
Pinto, C.1
Di Fabio, F.2
Barone, C.3
Siena, S.4
Falcone, A.5
Cascinu, S.6
Rojas Llimpe, F.L.7
Stella, G.8
Schinzari, G.9
Artale, S.10
Mutri, V.11
Giaquinta, S.12
Giannetta, L.13
Bardelli, A.14
Martoni, A.A.15
-
99
-
-
76349109904
-
Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer: A phase II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)
-
PMID: 20068568
-
Lordick F, Luber B, Lorenzen S, Hegewisch-Becker S, Folprecht G, Wöll E, Decker T, Endlicher E, Röthling N, Schuster T, Keller G, Fend F, Peschel C. Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer: a phase II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). Br J Cancer 2010; 102: 500-505 [PMID: 20068568 DOI: 10.1038/sj.bjc.6605521]
-
(2010)
Br J Cancer
, vol.102
, pp. 500-505
-
-
Lordick, F.1
Luber, B.2
Lorenzen, S.3
Hegewisch-Becker, S.4
Folprecht, G.5
Wöll, E.6
Decker, T.7
Endlicher, E.8
Röthling, N.9
Schuster, T.10
Keller, G.11
Fend, F.12
Peschel, C.13
-
100
-
-
58749089260
-
Phase II study and biomarker analysis of cetuximab combined with modified FOLFOX6 in advanced gastric cancer
-
PMID: 19127259
-
Han SW, Oh DY, Im SA, Park SR, Lee KW, Song HS, Lee NS, Lee KH, Choi IS, Lee MH, Kim MA, Kim WH, Bang YJ, Kim TY. Phase II study and biomarker analysis of cetuximab combined with modified FOLFOX6 in advanced gastric cancer. Br J Cancer 2009; 100: 298-304 [PMID: 19127259 DOI: 10.1038/sj.bjc.6604861]
-
(2009)
Br J Cancer
, vol.100
, pp. 298-304
-
-
Han, S.W.1
Oh, D.Y.2
Im, S.A.3
Park, S.R.4
Lee, K.W.5
Song, H.S.6
Lee, N.S.7
Lee, K.H.8
Choi, I.S.9
Lee, M.H.10
Kim, M.A.11
Kim, W.H.12
Bang, Y.J.13
Kim, T.Y.14
-
101
-
-
79957864676
-
Cetuximab with irinotecan, folinic acid and 5-fluorouracil as first-line treatment in advanced gastroesophageal cancer: A prospective multi-center biomarker-oriented phase II study
-
PMID: 21119032
-
Moehler M, Mueller A, Trarbach T, Lordick F, Seufferlein T, Kubicka S, Geissler M, Schwarz S, Galle PR, Kanzler S. Cetuximab with irinotecan, folinic acid and 5-fluorouracil as first-line treatment in advanced gastroesophageal cancer: a prospective multi-center biomarker-oriented phase II study. Ann Oncol 2011; 22: 1358-1366 [PMID: 21119032 DOI: 10.1093/annonc/mdq591]
-
(2011)
Ann Oncol
, vol.22
, pp. 1358-1366
-
-
Moehler, M.1
Mueller, A.2
Trarbach, T.3
Lordick, F.4
Seufferlein, T.5
Kubicka, S.6
Geissler, M.7
Schwarz, S.8
Galle, P.R.9
Kanzler, S.10
-
102
-
-
79957539777
-
A prospective phase II study of cetuximab in combination with XELOX (capecitabine and oxaliplatin) in patients with metastatic and/or recurrent advanced gastric cancer
-
PMID: 19997960
-
Kim C, Lee JL, Ryu MH, Chang HM, Kim TW, Lim HY, Kang HJ, Park YS, Ryoo BY, Kang YK. A prospective phase II study of cetuximab in combination with XELOX (capecitabine and oxaliplatin) in patients with metastatic and/or recurrent advanced gastric cancer. Invest New Drugs 2011; 29: 366-373 [PMID: 19997960 DOI: 10.1007/s10637-009-9363-0]
-
(2011)
Invest New Drugs
, vol.29
, pp. 366-373
-
-
Kim, C.1
Lee, J.L.2
Ryu, M.H.3
Chang, H.M.4
Kim, T.W.5
Lim, H.Y.6
Kang, H.J.7
Park, Y.S.8
Ryoo, B.Y.9
Kang, Y.K.10
-
103
-
-
84876951761
-
Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): A randomised, open-label phase 3 trial
-
PMID: 23594786
-
Lordick F, Kang YK, Chung HC, Salman P, Oh SC, Bodoky G, Kurteva G, Volovat C, Moiseyenko VM, Gorbunova V, Park JO, Sawaki A, Celik I, Götte H, Melezínková H, Moehler M. Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial. Lancet Oncol 2013; 14: 490-499 [PMID: 23594786 DOI: 10.1016/S1470-2045(13)70102-5]
-
(2013)
Lancet Oncol
, vol.14
, pp. 490-499
-
-
Lordick, F.1
Kang, Y.K.2
Chung, H.C.3
Salman, P.4
Oh, S.C.5
Bodoky, G.6
Kurteva, G.7
Volovat, C.8
Moiseyenko, V.M.9
Gorbunova, V.10
Park, J.O.11
Sawaki, A.12
Celik, I.13
Götte, H.14
Melezínková, H.15
Moehler, M.16
-
104
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
PMID: 20921465
-
Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, Błasiñska-Morawiec M, Šmakal M, Canon JL, Rother M, Oliner KS, Wolf M, Gansert J. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010; 28: 4697-4705 [PMID: 20921465 DOI: 10.1200/JCO.2009.27.4860]
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
Humblet, Y.7
Bodoky, G.8
Cunningham, D.9
Jassem, J.10
Rivera, F.11
Kocákova, I.12
Ruff, P.13
Błasiñska-Morawiec, M.14
Šmakal, M.15
Canon, J.L.16
Rother, M.17
Oliner, K.S.18
Wolf, M.19
Gansert, J.20
more..
-
105
-
-
38049047178
-
Capecitabine and oxaliplatin for advanced esophagogastric cancer
-
PMID: 18172173
-
Cunningham D, Starling N, Rao S, Iveson T, Nicolson M, Coxon F, Middleton G, Daniel F, Oates J, Norman AR. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N Engl J Med 2008; 358: 36-46 [PMID: 18172173 DOI: 10.1056/NEJMoa073149]
-
(2008)
N Engl J Med
, vol.358
, pp. 36-46
-
-
Cunningham, D.1
Starling, N.2
Rao, S.3
Iveson, T.4
Nicolson, M.5
Coxon, F.6
Middleton, G.7
Daniel, F.8
Oates, J.9
Norman, A.R.10
-
106
-
-
84876992498
-
Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): A randomised, open-label phase 3 trial
-
PMID: 23594787
-
Waddell T, Chau I, Cunningham D, Gonzalez D, Okines AF, Okines C, Wotherspoon A, Saffery C, Middleton G, Wadsley J, Ferry D, Mansoor W, Crosby T, Coxon F, Smith D, Waters J, Iveson T, Falk S, Slater S, Peckitt C, Barbachano Y. Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial. Lancet Oncol 2013; 14: 481-489 [PMID: 23594787 DOI: 10.1016/S1470-2045(13)70096-2]
-
(2013)
Lancet Oncol
, vol.14
, pp. 481-489
-
-
Waddell, T.1
Chau, I.2
Cunningham, D.3
Gonzalez, D.4
Okines, A.F.5
Okines, C.6
Wotherspoon, A.7
Saffery, C.8
Middleton, G.9
Wadsley, J.10
Ferry, D.11
Mansoor, W.12
Crosby, T.13
Coxon, F.14
Smith, D.15
Waters, J.16
Iveson, T.17
Falk, S.18
Slater, S.19
Peckitt, C.20
Barbachano, Y.21
more..
-
107
-
-
77957552916
-
Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for advanced esophagogastric cancer: Dose-finding study for the prospective multicenter, randomized, phase II/III REAL-3 trial
-
PMID: 20679619
-
Okines AF, Ashley SE, Cunningham D, Oates J, Turner A, Webb J, Saffery C, Chua YJ, Chau I. Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for advanced esophagogastric cancer: dose-finding study for the prospective multicenter, randomized, phase II/III REAL-3 trial. J Clin Oncol 2010; 28: 3945-3950 [PMID: 20679619 DOI: 10.1200/JCO.2010.29.2847]
-
(2010)
J Clin Oncol
, vol.28
, pp. 3945-3950
-
-
Okines, A.F.1
Ashley, S.E.2
Cunningham, D.3
Oates, J.4
Turner, A.5
Webb, J.6
Saffery, C.7
Chua, Y.J.8
Chau, I.9
-
108
-
-
84876978978
-
Optimal combination therapy for advanced colorectal cancer: An examination of synergy and antagonism with EGFR inhibition
-
Vora N, Evans S, Bernard PJ, Francisco F, Nagourney RA. Optimal combination therapy for advanced colorectal cancer: an examination of synergy and antagonism with EGFR inhibition. Proc Am Soc Clin Oncol 2012; 30 (suppl): abstr e14075
-
(2012)
Proc Am Soc Clin Oncol
, vol.30
-
-
Vora, N.1
Evans, S.2
Bernard, P.J.3
Francisco, F.4
Nagourney, R.A.5
-
109
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
-
PMID: 21641636
-
Maughan TS, Adams RA, Smith CG, Meade AM, Seymour MT, Wilson RH, Idziaszczyk S, Harris R, Fisher D, Kenny SL, Kay E, Mitchell JK, Madi A, Jasani B, James MD, Bridgewater J, Kennedy MJ, Claes B, Lambrechts D, Kaplan R, Cheadle JP. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet 2011; 377: 2103-2114 [PMID: 21641636 DOI: 10.1016/S0140-6736(11)60613-2]
-
(2011)
Lancet
, vol.377
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
Meade, A.M.4
Seymour, M.T.5
Wilson, R.H.6
Idziaszczyk, S.7
Harris, R.8
Fisher, D.9
Kenny, S.L.10
Kay, E.11
Mitchell, J.K.12
Madi, A.13
Jasani, B.14
James, M.D.15
Bridgewater, J.16
Kennedy, M.J.17
Claes, B.18
Lambrechts, D.19
Kaplan, R.20
Cheadle, J.P.21
more..
-
110
-
-
84875216070
-
Phase III multi-centre, randomized, double-blind, placebo-controlled trials of gefitinib versus placebo in esophageal cancer progressing after chemotherapy, COG (cancer oesophagus gefitinib)
-
Ferry DR, Dutton SJ, Mansoor W. Phase III multi-centre, randomized, double-blind, placebo-controlled trials of gefitinib versus placebo in esophageal cancer progressing after chemotherapy, COG (cancer oesophagus gefitinib). Ann Oncol 2012; 23 (suppl 9): ixe12
-
(2012)
Ann Oncol
, vol.23
, pp. ixe12
-
-
Ferry, D.R.1
Dutton, S.J.2
Mansoor, W.3
-
111
-
-
77958496605
-
Matuzumab plus epirubicin, cisplatin and capecitabine (ECX) compared with epirubicin, cisplatin and capecitabine alone as first-line treatment in patients with advanced oesophago-gastric cancer: A randomised, multicentre open-label phase II study
-
PMID: 20497967
-
Rao S, Starling N, Cunningham D, Sumpter K, Gilligan D, Ruhstaller T, Valladares-Ayerbes M, Wilke H, Archer C, Kurek R, Beadman C, Oates J. Matuzumab plus epirubicin, cisplatin and capecitabine (ECX) compared with epirubicin, cisplatin and capecitabine alone as first-line treatment in patients with advanced oesophago-gastric cancer: a randomised, multicentre open-label phase II study. Ann Oncol 2010; 21: 2213-2219 [PMID: 20497967 DOI: 10.1093/annonc/mdq247]
-
(2010)
Ann Oncol
, vol.21
, pp. 2213-2219
-
-
Rao, S.1
Starling, N.2
Cunningham, D.3
Sumpter, K.4
Gilligan, D.5
Ruhstaller, T.6
Valladares-Ayerbes, M.7
Wilke, H.8
Archer, C.9
Kurek, R.10
Beadman, C.11
Oates, J.12
-
112
-
-
84879117062
-
Phase I study of matuzumab in combination with 5-fluorouracil, leucovorin and cisplatin (PLF) in patients with advanced gastric and esophagogastric adenocarcinomas
-
PMID: 22763610
-
Trarbach T, Przyborek M, Schleucher N, Heeger S, Lüpfert C, Vanhoefer U. Phase I study of matuzumab in combination with 5-fluorouracil, leucovorin and cisplatin (PLF) in patients with advanced gastric and esophagogastric adenocarcinomas. Invest New Drugs 2013; 31: 642-652 [PMID: 22763610 DOI: 10.1007/s10637-012-9848-0]
-
(2013)
Invest New Drugs
, vol.31
, pp. 642-652
-
-
Trarbach, T.1
Przyborek, M.2
Schleucher, N.3
Heeger, S.4
Lüpfert, C.5
Vanhoefer, U.6
-
114
-
-
77953458271
-
ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity
-
PMID: 20484018
-
Munshi N, Jeay S, Li Y, Chen CR, France DS, Ashwell MA, Hill J, Moussa MM, Leggett DS, Li CJ. ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity. Mol Cancer Ther 2010; 9: 1544-1553 [PMID: 20484018 DOI: 10.1158/1535-7163.MCT-09-1173]
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1544-1553
-
-
Munshi, N.1
Jeay, S.2
Li, Y.3
Chen, C.R.4
France, D.S.5
Ashwell, M.A.6
Hill, J.7
Moussa, M.M.8
Leggett, D.S.9
Li, C.J.10
-
115
-
-
84896404764
-
A phase II trial of a selective c-Met inhibitor tivantinib (ARQ 197) monotherapy as a second- or third-line therapy in the patients with metastatic gastric cancer
-
PMID: 24337769
-
Kang YK, Muro K, Ryu MH, Yasui H, Nishina T, Ryoo BY, Kamiya Y, Akinaga S, Boku N. A phase II trial of a selective c-Met inhibitor tivantinib (ARQ 197) monotherapy as a second- or third-line therapy in the patients with metastatic gastric cancer. Invest New Drugs 2014; 32: 355-361 [PMID: 24337769 DOI: 10.1007/s10637-013-0057-2]
-
(2014)
Invest New Drugs
, vol.32
, pp. 355-361
-
-
Kang, Y.K.1
Muro, K.2
Ryu, M.H.3
Yasui, H.4
Nishina, T.5
Ryoo, B.Y.6
Kamiya, Y.7
Akinaga, S.8
Boku, N.9
-
116
-
-
79960847995
-
Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells
-
PMID: 21730976
-
Okamoto W, Okamoto I, Arao T, Yanagihara K, Nishio K, Nakagawa K. Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells. Br J Cancer 2011; 105: 407-412 [PMID: 21730976 DOI: 10.1038/bjc.2011.246]
-
(2011)
Br J Cancer
, vol.105
, pp. 407-412
-
-
Okamoto, W.1
Okamoto, I.2
Arao, T.3
Yanagihara, K.4
Nishio, K.5
Nakagawa, K.6
|