-
1
-
-
13144305649
-
Biology of lung cancer
-
J. F. Murray and J. A. Nadel (eds.). 2nd ed., Philadelphia: W. B. Saunders
-
Chia, M. M., Gazdar, A. F., Carone, D. P., and Minna J. P. Biology of lung cancer. In: J. F. Murray and J. A. Nadel (eds.). Textbook of Respiratory Medicine, 2nd ed., pp. 1485-1503. Philadelphia: W. B. Saunders, 1994.
-
(1994)
Textbook of Respiratory Medicine
, pp. 1485-1503
-
-
Chia, M.M.1
Gazdar, A.F.2
Carone, D.P.3
Minna, J.P.4
-
2
-
-
0001434929
-
Small cell lung cancer
-
V. T. DeVita, S. Hellman, and S. A. Rosenberg (eds.), 6th ed., Philadelphia: Lippincott Williams & Wilkins
-
Murren, J., Glatstein, E., and Pass, H. I. Small cell lung cancer. In: V. T. DeVita, S. Hellman, and S. A. Rosenberg (eds.), Cancer: Principles & Practice of Oncology, 6th ed., pp. 983-1018. Philadelphia: Lippincott Williams & Wilkins, 1993.
-
(1993)
Cancer: Principles & Practice of Oncology
, pp. 983-1018
-
-
Murren, J.1
Glatstein, E.2
Pass, H.I.3
-
3
-
-
0028252924
-
Steel factor and c-kit protooncogene: Genetic lessons in signal transduction
-
Lev, S., Blechman, J. M., Givol, D., and Yarden, Y. Steel factor and c-kit protooncogene: genetic lessons in signal transduction. Crit. Rev. Oncog., 5: 141-168, 1994.
-
(1994)
Crit. Rev. Oncog.
, vol.5
, pp. 141-168
-
-
Lev, S.1
Blechman, J.M.2
Givol, D.3
Yarden, Y.4
-
4
-
-
0030069519
-
Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor
-
Krystal, G. W., Hines, S. J., and Organ, C. P. Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor. Cancer Res., 56: 370-376, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 370-376
-
-
Krystal, G.W.1
Hines, S.J.2
Organ, C.P.3
-
5
-
-
0033883060
-
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors
-
Lux, M. L., Rubin, B. P., Biase, T. L., Chen, C. J., Maclure, T., Demetri, G., Xiao, S., Singer, S., Fletcher, C. D., and Fletcher, J. A. KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors. Am. J. Pathol., 156: 791-795, 2000. (Pubitemid 30626936)
-
(2000)
American Journal of Pathology
, vol.156
, Issue.3
, pp. 791-795
-
-
Lux, M.L.1
Rubin, B.P.2
Biase, T.L.3
Chen, C.-J.4
Maclure, T.5
Demetri, G.6
Xiao, S.7
Singer, S.8
Fletcher, C.D.M.9
Fletcher, J.A.10
-
6
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
DOI 10.1126/science.279.5350.577
-
Hirota, S., Isozaki, K., Moriyama, Y., Hashimoto, K., Nishida, T., Ishiguro, S., Kawano, K., Hanada, M., Kurata, A., Takeda, M., Muhammad Tunio, G., Matsuzawa, Y., Kanakura, Y., Shinomura, Y., and Kitamura, Y. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science (Wash. DC), 279: 577-580, 1998. (Pubitemid 28067289)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Tunio, G.M.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
7
-
-
0033800085
-
c-Kit and c-kit mutations in mastocytosis and other hematological diseases
-
Boissan, M., Feger, F., Guillosson, J. J., and Arock, M. c-Kit and c-kit mutations in mastocytosis and other hematological diseases. J. Leukocyte Biol., 67: 135-148, 2000.
-
(2000)
J. Leukocyte Biol.
, vol.67
, pp. 135-148
-
-
Boissan, M.1
Feger, F.2
Guillosson, J.J.3
Arock, M.4
-
8
-
-
0030980383
-
Induction of apoptosis and inhibition of small cell lung cancer growth by the quinoxaline tyrphostins
-
Krystal, G. W., Carlson, P., and Litz, J. Induction of apoptosis and inhibition of small cell lung cancer growth by the quinoxaline tyrphostins. Cancer Res., 57: 2203-2208, 1997. (Pubitemid 27247039)
-
(1997)
Cancer Research
, vol.57
, Issue.11
, pp. 2203-2208
-
-
Krystal, G.W.1
Carlson, P.2
Litz, J.3
-
9
-
-
0035328851
-
Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells
-
Krystal, G. W., Honsawek, S., Kiewlich, D., Liang, C., Vasile, S., Sun, L., McMahon, G., and Lipson, K. E. Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells. Cancer Res., 61: 3660-3668, 2001. (Pubitemid 32694977)
-
(2001)
Cancer Research
, vol.61
, Issue.9
, pp. 3660-3668
-
-
Krystal, G.W.1
Honsawek, S.2
Kiewlich, D.3
Liang, C.4
Vasile, S.5
Sun, L.6
McMahon, G.7
Lipson, K.E.8
-
10
-
-
0033883653
-
The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth
-
Krystal, G. W., Honsawek, S., Litz, J., and Buchdunger, E. The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth. Clin. Cancer Res., 6: 3319-3326, 2000. (Pubitemid 30637763)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.8
, pp. 3319-3326
-
-
Krystal, G.W.1
Honsawek, S.2
Litz, J.3
Buchdunger, E.4
-
11
-
-
0034691761
-
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571
-
Wang, W. L., Healy, M. E., Sattler, M., Verma, S., Lin, J., Maulik, G., Stiles, C. D., Griffin, J. D., Johnson, B. E., and Salgia, R. Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. Oncogene, 19: 3521-3528, 2000. (Pubitemid 30487449)
-
(2000)
Oncogene
, vol.19
, Issue.31
, pp. 3521-3528
-
-
Wang W.-L1
Healy, M.E.2
Sattler, M.3
Verma, S.4
Lin, J.5
Maulik, G.6
Stiles, C.D.7
Griffin, J.D.8
Johnson, B.E.9
Salgia, R.10
-
12
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel, D. B., Laird, A. D., Xin, X., Louie, S. G., Christensen, J. G., Li, G., Schreck, R. E., Abrams, T. J., Ngai, T. J., Lee, L. B., Murray, L. J., Carver, J., Chan, E., Moss, K. G., Haznedar, J. O., Sukbuntherng, J., Blake, R. A., Sun, C., Tang, C., Miller, T., Shirazian, S., McMahon, G. and Cherrington, J. M. In vivo anti-tumor activity of SU11248, a novel tyrosine kinase inhibitor targeting VEGF and PDGF receptors: determination of a pharmacokinetic/ pharmacodynamic relationship. Clin. Cancer Res., 9: 327-337, 2002. (Pubitemid 36109749)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.1 I
, pp. 327-337
-
-
Mendel, D.B.1
Douglas, L.A.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
Chan, E.13
Moss, K.G.14
Haznedar, J.O.15
Sukbuntherng, J.16
Blake, R.A.17
Sun, L.18
Tang, C.19
Miller, T.20
Shirazian, S.21
McMahon, G.22
Cherrington, J.M.23
more..
-
13
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
in press
-
O'Farrell, A. M., Abrams, T. J., Yuen, H. A., Ngai, T. J., Louie, S. G., Yee, K. W. H., Wong, L. M., Hong, W. M., Lee, L. B., Town, A., Smolich, B. D., Manning, W. C., Murray, L. J., Heinrich, M. C., and Cherrington, J. M. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood, in press, 2003.
-
(2003)
Blood
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.H.6
Wong, L.M.7
Hong, W.M.8
Lee, L.B.9
Town, A.10
Smolich, B.D.11
Manning, W.C.12
Murray, L.J.13
Heinrich, M.C.14
Cherrington, J.M.15
-
14
-
-
0033650988
-
New paradigms for the treatment of cancer; the role of anti-angiogenesis agents
-
G. Klein and G. F. Vande Woude (eds.), 1st ed., San Diego, CA: Academic Press
-
Cherrington, J. M., Strawn, L. M., and Shawver, L. K. New paradigms for the treatment of cancer; the role of anti-angiogenesis agents. In: G. Klein and G. F. Vande Woude (eds.), Advances in Cancer Research, 1st ed., pp. 1-38. San Diego, CA: Academic Press, 2000.
-
(2000)
Advances in Cancer Research
, pp. 1-38
-
-
Cherrington, J.M.1
Strawn, L.M.2
Shawver, L.K.3
-
15
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker, B. J., Tamura, S., Buchdunger, E., Ohno, S., Segal, G. M., Fanning, S., Zimmermann, J., and Lydon, N. B. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med., 2: 561-566, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.B.8
-
16
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
Carroll, M., Ohno-Jones, S., Tamura, S., Buchdunger, E., Zimmermann, J., Lydon, N. B., Gilliland, D. G., and Druker, B. J. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood, 90: 4947-4952, 1997. (Pubitemid 28007210)
-
(1997)
Blood
, vol.90
, Issue.12
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmermann, J.5
Lydon, N.B.6
Gilliland, D.G.7
Druker, B.J.8
-
17
-
-
0035525787
-
Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571
-
Wolff, N. C., and Ilaria, R. L., Jr. Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571. Blood, 98: 2808-2816, 2001.
-
(2001)
Blood
, vol.98
, pp. 2808-2816
-
-
Wolff, N.C.1
Ilaria Jr., R.L.2
-
18
-
-
0035421175
-
Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis
-
Sjoblom, T., Shimizu, A., O'Brien, K. P., Pietras, K., Dal Cin, P., Buchdunger, E., Dumanski, J. P., Ostman, A., and Heldin, C-H. Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis. Cancer Res., 61: 5778-5783, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 5778-5783
-
-
Sjoblom, T.1
Shimizu, A.2
O'Brien, K.P.3
Pietras, K.4
Dal Cin, P.5
Buchdunger, E.6
Dumanski, J.P.7
Ostman, A.8
Heldin, C.-H.9
-
19
-
-
0033585504
-
In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor
-
Bethesda
-
le Coutre, P., Mologni, L., Cleris, L., Marchesi, E., Buchdunger, E., Giardini, R., Formelli, F., and Gambacorti-Passerini, C. In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor. J. Natl. Cancer Inst. (Bethesda), 91: 163-168, 1999.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 163-168
-
-
Le Coutre, P.1
Mologni, L.2
Cleris, L.3
Marchesi, E.4
Buchdunger, E.5
Giardini, R.6
Formelli, F.7
Gambacorti-Passerini, C.8
-
20
-
-
0033816156
-
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
-
Buchdunger, E., Cioffi, C. L., Law, N., Stover, D., Ohno-Jones, S., Druker, B. J., and Lydon, N. B. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J. Pharmacol. Exp. Ther., 295: 139-145, 2000.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 139-145
-
-
Buchdunger, E.1
Cioffi, C.L.2
Law, N.3
Stover, D.4
Ohno-Jones, S.5
Druker, B.J.6
Lydon, N.B.7
-
21
-
-
0035742095
-
Current standards of care in small-cell and non-small-cell lung cancer
-
Basel
-
Schiller, J. H. Current standards of care in small-cell and non-small-cell lung cancer. Oncology (Basel), 61 (Suppl.): 3-13, 2001.
-
(2001)
Oncology
, vol.61
, Issue.SUPPL.
, pp. 3-13
-
-
Schiller, J.H.1
-
22
-
-
0026318821
-
Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer
-
Hibi, K., Takahashi, T., Sekido, Y., Ueda, R., Hida, T., Ariyoshi, Y., and Takagi, H. Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer. Oncogene, 6: 2291-2296, 1991. (Pubitemid 21924076)
-
(1991)
Oncogene
, vol.6
, Issue.12
, pp. 2291-2296
-
-
Hibi, K.1
Takahashi, T.2
Sekido, Y.3
Ueda, R.4
Hida, T.5
Ariyoshi, Y.6
Takagi, H.7
Takahashi, T.8
-
23
-
-
0027818682
-
c-myc Expression correlates with suppression of c-kit protooncogene expression in small cell lung cancer cell lines
-
Plummer, H., III, Catlett, J., Leftwich, J., Armstrong, B., Carlson, P., Huff, T., and Krystal, G. c-myc expression correlates with suppression of c-kit protooncogene expression in small cell lung cancer cell lines. Cancer Res., 53: 4337-4342, 1993. (Pubitemid 24146787)
-
(1993)
Cancer Research
, vol.53
, Issue.18
, pp. 4337-4342
-
-
Plummer III, H.1
Catlett, J.2
Leftwich, J.3
Armstrong, B.4
Carlson, P.5
Huff, T.6
Krystal, G.7
-
24
-
-
0027390395
-
Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts
-
Rygaard, K., Nakamura, T., and Spang-Thomsen, M. Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts. Br. J. Cancer, 67: 37-46, 1993. (Pubitemid 23034921)
-
(1993)
British Journal of Cancer
, vol.67
, Issue.1
, pp. 37-46
-
-
Rygaard, K.1
Nakamura, T.2
Spang-Thomsen, M.3
-
25
-
-
84880152665
-
Differential expression of c-kit in lung carcinomas; implications for possible use of the tyrosine kinase inhibitor STI571 in lung cancer
-
Siziopikou, K. P., Cosar, E., Morgan, M., and Husain, A. N. Differential expression of c-kit in lung carcinomas; implications for possible use of the tyrosine kinase inhibitor STI571 in lung cancer. Proc. Am. Assoc. Cancer Res., 43: 755-756, 2002.
-
(2002)
Proc. Am. Assoc. Cancer Res.
, vol.43
, pp. 755-756
-
-
Siziopikou, K.P.1
Cosar, E.2
Morgan, M.3
Husain, A.N.4
-
26
-
-
0032197408
-
Leflunomide approved for rheumatoid arthritis; other drugs nearing approval
-
Leflunomide approved for rheumatoid arthritis; other drugs nearing approval. Am. J. Health Syst. Pharm., 55: 2225-2226, 1998.
-
(1998)
Am. J. Health Syst. Pharm.
, vol.55
, pp. 2225-2226
-
-
-
27
-
-
0033571749
-
Identification of breast cancer cell line-derived paracrine factors that stimulate osteoclast activity
-
Pederson, L., Winding, B., Foged, N. T., Spelsberg, T. C., and Oursler, M. J. Identification of breast cancer cell line-derived paracrine factors that stimulate osteoclast activity. Cancer Res., 59: 5849-5855, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 5849-5855
-
-
Pederson, L.1
Winding, B.2
Foged, N.T.3
Spelsberg, T.C.4
Oursler, M.J.5
-
28
-
-
0029047695
-
Vascular permeability factor/vascular endothelial growth factor: An important mediator of angiogenesis in malignancy and inflammation
-
Dvorak, H. F., Detmar, M., Claffey, K. P., Nagy, J. A., van de Water, L., and Senger, D. R. Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. Int. Arch. Allergy Immunol., 107: 233-235, 1995.
-
(1995)
Int. Arch. Allergy Immunol.
, vol.107
, pp. 233-235
-
-
Dvorak, H.F.1
Detmar, M.2
Claffey, K.P.3
Nagy, J.A.4
Van De Water, L.5
Senger, D.R.6
-
29
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
DOI 10.1016/S0092-8674(00)80108-7
-
Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996. (Pubitemid 26272076)
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
30
-
-
0031942430
-
High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer
-
DOI 10.1002/(SICI)1097-0215(19980417)79:2<144::AID
-
Salven, P., Ruotsalainen, T., Mattson, K., and Joensuu, H. High pretreatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer. Int. J. Cancer, 79: 144-146, 1998. (Pubitemid 28201685)
-
(1998)
International Journal of Cancer
, vol.79
, Issue.2
, pp. 144-146
-
-
Salven, P.1
Ruotsalainen, T.2
Mattson, K.3
Joensuu, H.4
-
31
-
-
0036080185
-
Serum vascular endothelial growth factor levels correlate better with tumour stage in small cell lung cancer than albumin, neuron-specific enolase or lactate dehydrogenase
-
DOI 10.1046/j.1440-1843.2002.00386.x
-
Mall, J. W., Schwenk, W., Philipp, A. W., Meyer-Kipker, C., Mall, W., Muller, J., and Pollmann, C. Serum vascular endothelial growth factor levels correlate better with tumour stage in small cell lung cancer than albumin, neuron-specific enolase or lactate dehydrogenase. Respirology, 7: 99-102, 2002. (Pubitemid 34662939)
-
(2002)
Respirology
, vol.7
, Issue.2
, pp. 99-102
-
-
Mall, J.W.1
Schwenk, W.2
Philipp, A.W.3
Meyer-Kipker, C.4
Mall, W.5
Muller, J.6
Pollmann, C.7
-
32
-
-
0036017044
-
Small cell lung carcinoma (SCLC): The angiogenic phenomenon
-
Lucchi, M., Mussi, A., Fontanini, G., Faviana, P., Ribechini, A., and Angeletti, C. A. Small cell lung carcinoma (SCLC): the angiogenic phenomenon. Eur. J. Cardio-thoracic Surg., 21: 1105-1110, 2002.
-
(2002)
Eur. J. Cardio-thoracic Surg.
, vol.21
, pp. 1105-1110
-
-
Lucchi, M.1
Mussi, A.2
Fontanini, G.3
Faviana, P.4
Ribechini, A.5
Angeletti, C.A.6
|