Mechanism of amyloid-β fibril elongation

Biochemistry

Volumn 53, Issue 44, 2014, Pages 6981-6991

  Gurry, Thomas ^a   Stultz, Collin M ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b Department of Electrical Engineering and Computer Science   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION; FREE ENERGY; HYDROGEN BONDS; MOLECULAR DYNAMICS; MONOMERS; NEURODEGENERATIVE DISEASES; OLIGOMERS;

ALZHEIMER'S DISEASE; AMYLOID FIBRIL; FIBRIL ELONGATION; INTRINSICALLY DISORDERED PROTEINS; MOLECULAR DYNAMICS SIMULATIONS; SECONDARY NUCLEATION; STRUCTURAL LINKS; UMBRELLA SAMPLING;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; MONOMER; OLIGOMER; AMYLOID; AMYLOID BETA-PROTEIN (1-42); AMYLOID BETA-PROTEIN (17-42); PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; BRAIN; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; PROTEIN DEGRADATION; PROTEIN FOLDING; CHEMISTRY; KINETICS; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; THERMODYNAMICS;

AMYLOID; AMYLOID BETA-PEPTIDES; HUMANS; HYDROGEN BONDING; KINETICS; MOLECULAR DYNAMICS SIMULATION; PEPTIDE FRAGMENTS; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS;

EID: 84909594439     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500695g     Document Type: Article

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