SCCA1/SERPINB3 promotes oncogenesis and epithelial-mesenchymal transition via the unfolded protein response and IL6 signaling

Cancer Research

Volumn 74, Issue 21, 2014, Pages 6318-6329

  Sheshadri, Namratha ^a   Catanzaro, Joseph M ^a   Bott, Alex J ^a   Sun, Yu ^a   Ullman, Erica ^a   Chen, Emily I ^a   Pan, Ji An ^a   Wu, Song ^b   Crawford, Howard C ^c   Zhang, Jianhua ^d   Zong, Wei Xing ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b Stony Brook University   (United States)

^c MAYO CLINIC   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR B3; UNCLASSIFIED DRUG; IL6 PROTEIN, HUMAN; SQUAMOUS CELL CARCINOMA-RELATED ANTIGEN; TUMOR ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BREAST CANCER CELL LINE; BREAST TUMOR; CARCINOGENESIS; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE INDUCTION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN UNFOLDING; SERPINB3 GENE; TRANSCRIPTION INITIATION; TUMOR MICROENVIRONMENT; UNFOLDED PROTEIN RESPONSE; BIOSYNTHESIS; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CARCINOGENESIS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; NF-KAPPA B; SERPINS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84909592613     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0798     Document Type: Article

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