Suppression of a squamous cell carcinoma (scc)-related serpin, scc antigen, inhibits tumor growth with increased intratumor infiltration of natural killer cells

Cancer Research

Volumn 61, Issue 5, 2001, Pages 1776-1780

  Suminami, Yoshinori ^a   Nagashima, Shigeki ^b   Murakami, Akihiro ^a   Nawata, Shugo ^a   Gondo, Toshikazu ^a   Hirakawa, Hiroshi ^a   Numa, Fumitaka ^a   Silverman, Gary A ^c   Kato, Hiroshi ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN; SERINE PROTEINASE INHIBITOR; SQUAMOUS CELL CARCINOMA ANTIGEN; TUMOR MARKER;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NATURAL KILLER CELL; NUDE MOUSE; PRIORITY JOURNAL; RETROVIRUS; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; VIRUS INFECTION;

3T3 CELLS; ANIMALS; ANTIGENS, NEOPLASM; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL MOVEMENT; HUMANS; KILLER CELLS, NATURAL; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; OLIGONUCLEOTIDES, ANTISENSE; SERPINS; TRANSDUCTION, GENETIC;

EID: 0035266148     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Radioimmunoassay for tumor-antigen of human cervical squamous cell carcinoma
2. Availability of tumor-antigen 4 as a marker of squamous cell carcinoma of the lung and other organs
3. Squamous cell carcinoma antigen
4. Heterogeneity of a tumor antigen TA-4 of squamous cell carcinoma in relation to its appearance in the circulation
5. Identification of squamous cell carcinoma antigen-2 in tumor tissue by two-dimensional electrophoresis
6. Squamous cell carcinoma antigen is a new member of the serine protease inhibitors
7. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene
8. Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis
9. Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase
10. Electrophoretic analysis of the "cross-class" interaction between novel inhibitory serpin, squamous cell carcinoma antigen-1 and cysteine proteinases
11. Inhibition of apoptosis in human tumor cells by the tumor-associated serpin, SCC antigen-1
12. Vitro and in vivo characteristics of human squamous cell carcinoma of the head and neck cells engineered to secrete interleukin-2
13. Different behaviors in the production and release of SCC antigen in squamous-cell carcinoma
14. Nonsecretory apoptotic killing by human NK Cells
15. The reactive site loop of the serpin SCCA1 is essential for cysteine proteinase inhibition
16. Specific detection and quantitation of SCC antigen-1 and SCC antigen-2 mRNA by fluorescence-based asymmetric semi-nested reverse transcription PCR
17. CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis
18. Plasminogen activator inhibitor type 2 inhibits tumor necrosis factor α-induced apoptosis. Evidence for an alternate biological function
19. A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes
20. Pretreatment serum SCC antigen: A new prognostic factor in early stage cervical carcinoma