GATA binding protein 2 mediates leptin inhibition of PPARγ1 expression in hepatic stellate cells and contributes to hepatic stellate cell activation

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 12, 2014, Pages 2367-2377

  Zhou, Qian ^a   Guan, Wei ^a   Qiao, Haowen ^b   Cheng, Yuanyuan ^a   Li, Ziqiang ^b   Zhai, Xuguang ^b   Zhou, Yajun ^b  

^a NANTONG UNIVERSITY   (China)

^b NANTONG MEDICAL COLLEGE   (China)

Author keywords

GATA binding protein 2; Hepatic stellate cell; Leptin; Liver fibrosis; Peroxisome proliferator activated receptor 1

Indexed keywords

BETA CATENIN; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; PROTEIN BINDING; SHH PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELL ACTIVATION; DNA RESPONSIVE ELEMENT; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; STELLATE CELL; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; LIVER CIRRHOSIS; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BETA CATENIN; BINDING SITES; BLOTTING, WESTERN; CELLS, CULTURED; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION; HEDGEHOG PROTEINS; HEPATIC STELLATE CELLS; LEPTIN; LIVER CIRRHOSIS; MICE, INBRED C57BL; MICE, OBESE; PPAR GAMMA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84908676241     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.10.001     Document Type: Article

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