Antiarrhythmic effect of lithium in rats after myocardial infarction by activation of Nrf2/HO-1 signaling

Free Radical Biology and Medicine

Volumn 77, Issue , 2014, Pages 71-81

  Lee, Tsung Ming ^a,b,c   Lin, Shinn Zong ^a,b,d,e   Chang, Nen Chung ^c,f  

^a China Medical University An Nan Hospital   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Arrhythmias; Free radicals; Glycogen synthase kinase 3; Heme oxygenase 1; Lithium; Nuclear factor erythroid 2 related factor 2

Indexed keywords

ALKALOID; ANTIARRHYTHMIC AGENT; HEME OXYGENASE 1; LITHIUM CHLORIDE; NERVE GROWTH FACTOR; NFE2L2 PROTEIN, RAT; TRANSCRIPTION FACTOR NRF2; TRIGONELLINE;

ADRENERGIC SYSTEM; ANIMAL; ARRHYTHMIAS, CARDIAC; DRUG EFFECTS; DRUG SCREENING; ENZYMOLOGY; GENETICS; HEART; INNERVATION; MALE; METABOLISM; MYOCARDIAL INFARCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; WISTAR RAT;

ALKALOIDS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; DRUG EVALUATION, PRECLINICAL; HEART; HEME OXYGENASE-1; LITHIUM CHLORIDE; MALE; MYOCARDIAL INFARCTION; NERVE GROWTH FACTOR; NF-E2-RELATED FACTOR 2; PROTEIN TRANSPORT; RATS, WISTAR; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM;

EID: 84908669939     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.08.022     Document Type: Article

References (44)

1. P. Rada, A.I. Rojo, N. Evrard-Todeschi, N.G. Innamorato, A. Cotte, T. Jaworski, J.C. Tobón-Velasco, H. Devijver, M.F. García-Mayoral, F. Van Leuven, J.D. Hayes, G. Bertho, and A. Cuadrado Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis Mol. Cell. Biol. 32 2012 3486 3499
2. S. Espada, F. Ortega, E. Molina-Jijón, A.I. Rojo, R. Pérez-Sen, J. Pedraza-Chaverri, M.T. Miras-Portugal, and A. Cuadrado The purinergic P2Y(13) receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death Free Radic. Biol. Med. 49 2010 416 426
3. T.W. Kensler, N. Wakabayashi, and S. Biswal Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway Annu. Rev. Pharmacol. Toxicol. 47 2007 89 116
4. L.E. Otterbein, J.K. Kolls, L.L. Mantell, J.L. Cook, J. Alam, and A.M. Choi Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury J. Clin. Invest. 103 1999 1047 1054
5. K.D. Poss, and S. Tonegawa Reduced stress defense in heme oxygenase 1-deficient cells Proc. Natl. Acad. Sci. USA 94 1997 10925 10930
6. M. Salazar, A.I. Rojo, D. Velasco, R.M. de Sagarra, and A. Cuadrado Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2 J. Biol. Chem. 281 2006 14841 14851
7. T.M. Lee, P.Y. Lai, and N.C. Chang Effect of N-acetylcysteine on sympathetic hyperinnervation in post-infarcted rat hearts Cardiovasc. Res. 85 2010 137 146
8. T.M. Lee, C.C. Chen, and Y.J. Hsu Differential effect of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in post-infarcted rat hearts Free Radic. Biol. Med. 50 2011 1461 1470
9. T.M. Lee, S.Z. Lin, and N.C. Chang Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction PLoS One 8 2013 e71878
10. R. Vracko, D. Thorning, and R.G. Frederickson Fate of nerve fibers in necrotic, healing, and healed rat myocardium Lab. Invest. 63 1990 490 501
11. J.M. Cao, M.C. Fishbein, J.B. Han, W.W. Lai, A.C. Lai, T.J. Wu, L. Czer, P.L. Wolf, T.A. Denton, I.P. Shintaku, P.S. Chen, and L.S. Chen Relationship between regional cardiac hyperinnervation and ventricular arrhythmias Circulation 101 2000 1960 1969
12. W.D. Snider Functions of the neurotrophins during nervous system development: what the knockouts are teaching us Cell 77 1994 627 638
13. A.M. Colangelo, P.F. Johnson, and I. Mocchetti Beta-adrenergic receptor-induced activation of nerve growth factor gene transcription in rat cerebral cortex involves CCAAT/enhancer-binding protein delta Proc. Natl. Acad. Sci. USA 95 1998 10920 10925
14. C. Abate, L. Patel, F.J. Rauscher 3rd, and T. Curran Redox regulation of fos and jun DNA-binding activity in vitro Science 249 1990 1157 1161
15. M.R. Vargas, M. Pehar, P. Cassina, A.G. Estévez, J.S. Beckman, and L. Barbeito Stimulation of nerve growth factor expression in astrocytes by peroxynitrite In Vivo 18 2004 269 274
16. F. Angelucci, L. Aloe, P. Jiménez-Vasquez, and A.A. Mathé Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression Int. J. Neuropsychopharmacol. 6 2003 225 231
17. H. Paves, T. Neuman, M. Metsis, and M. Saarma Nerve growth factor-induced rapid reorganization of microfilaments in PC12 cells: possible roles of different second messenger systems Exp. Cell Res. 186 1990 218 226
18. D.E. Burstein, P.J. Seeley, and L.A. Greene Lithium ion inhibits nerve growth factor-induced neurite outgrowth and phosphorylation of nerve growth factor-modulated microtubule-associated proteins J. Cell Biol. 101 1985 862 870
19. J. Xu, A. Scholz, N. Rösch, A. Blume, T. Unger, R. Kreutz, J. Culman, and P. Gohlke Low-dose lithium combined with captopril prevents stroke and improves survival in salt-loaded, stroke-prone spontaneously hypertensive rats J. Hypertens. 23 2005 2277 2285
20. J. Zdychová, L. Kazdová, T. Pelikanová, J.N. Lindsley, S. Anderson, and R. Komers Renal activity of Akt kinase in obese Zucker rats Exp. Biol. Med. (Maywood) 233 2008 1231 1241
21. Q.G. Xia, O. Chung, H. Spitznagel, S. Illner, G. Jänichen, B. Rossius, P. Gohlke, and T. Unger Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure Cardiovasc. Res. 49 2001 110 117
22. M.A. Pfeffer, and E. Braunwald Ventricular remodeling after myocardial infarction Circulation 81 1990 161 172
23. A. Arlt, S. Sebens, S. Krebs, C. Geismann, M. Grossmann, M.L. Kruse, S. Schreiber, and H. Schäfer Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity Oncogene 32 2013 4825 4835
24. J.E. Clark, R. Foresti, C.J. Green, and R. Motterlini Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress Biochem. J. 348 2000 615 619
25. T.M. Lee, C.C. Chen, and N.C. Chang Cardiac sympathetic hyperinnervation in deoxycorticosterone acetate-salt hypertensive rats Clin. Sci. (London) 123 2012 445 457
26. J.M. Herre, L. Wetstein, Y.L. Lin, A.S. Mills, M. Dae, and M.D. Thames Effect of transmural versus nontransmural myocardial infarction on inducibility of ventricular arrhythmias during sympathetic stimulation in dogs J. Am. Coll. Cardiol. 11 1988 414 421
27. P. Bélichard, P. Savard, R. Cardinal, R. Nadeau, H. Gosselin, P. Paradis, and J.L. Rouleau Markedly different effects on ventricular remodeling result in a decrease in inducibility of ventricular arrhythmias J. Am. Coll. Cardiol. 23 1994 505 513
28. P.S. Shapiro, A.M. Whalen, N.S. Tolwinski, J. Wilsbacher, S.J. Froelich-Ammon, M. Garcia, N. Osheroff, and N.G. Ahn Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation Mol. Cell. Biol. 19 1999 3551 3560
29. T.M. Lee, M.S. Lin, T.F. Chou, C.H. Tsai, and N.C. Chang Adjunctive 17β-estradiol administration reduces infarct size by altered expression of canine myocardial connexin43 protein Cardiovasc. Res. 63 2004 109 117
30. M. Ahmad, Y. Elnakady, M. Farooq, and M. Wadaan Lithium induced toxicity in rats: blood serum chemistry, antioxidative enzymes in red blood cells and histopathological studies Biol. Pharm. Bull. 34 2011 272 277
31. C. Bergmann, A. Akhmetshina, C. Dees, K. Palumbo, P. Zerr, C. Beyer, J. Zwerina, O. Distler, G. Schett, and J.H. Distler Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway Ann. Rheum. Dis. 70 2011 2191 2198
32. R. Han, B. Gao, R. Sheng, L.S. Zhang, H.L. Zhang, Z.L. Gu, and Z.H. Qin Synergistic effects of prostaglandin E1 and lithium in a rat model of cerebral ischemia Acta Pharmacol. Sin. 29 2008 1141 1149
33. S. Kelsen, B.J. Patel, L.B. Parker, T. Vera, J.M. Rimoldi, R.S. Gadepalli, H.A. Drummond, and D.E. Stec Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells Am. J. Physiol. Renal Physiol 295 2008 F1158 F1165
34. R. Stocker, Y. Yamamoto, A.F. McDonagh, A.N. Glazer, and B.N. Ames Bilirubin is an antioxidant of possible physiological importance Science 235 1987 1043 1046
35. A. Pflueger, A.J. Croatt, T.E. Peterson, L.A. Smith, L.V. dUscio, Z.S. Katusic, and K.A. Nath The hyperbilirubinemic Gunn rat is resistant to the pressor effects of angiotensin II Am. J. Physiol. Renal Physiol 288 2005 F552 F558
36. T. Vera, S. Kelsen, L.L. Yanes, J.F. Reckelhoff, and D.E. Stec HO-1 induction lowers blood pressure and superoxide production in the renal medulla of angiotensin II hypertensive mice Am. J. Physiol. Regul. Integr. Comp. Physiol 292 2007 R1472 R1478
37. Z. Wang, J. Wang, J. Li, X. Wang, Y. Yao, X. Zhang, C. Li, Y. Cheng, G. Ding, L. Liu, and Z. Ding MEK/ERKs signaling is essential for lithium-induced neurite outgrowth in N2a cells Int. J. Dev. Neurosci. 29 2011 415 422
38. H.J. Song, and M.M. Poo Signal transduction underlying growth cone guidance by diffusible factors Curr. Opin. Neurobiol. 9 1999 355 363
39. J.J. Garrido, D. Simon, O. Varea, and F. Wandosell GSK3 alpha and GSK3 beta are necessary for axon formation FEBS Lett. 581 2007 1579 1586
40. W.T. OBrien, A.D. Harper, F. Jové, J.R. Woodgett, S. Maretto, S. Piccolo, and P.S. Klein Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium J. Neurosci. 24 2004 6791 6798
41. C.M. Hu, Y.H. Chen, M.T. Chiang, and L.Y. Chau Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo Circulation 110 2004 309 316
42. L. Baird, and A.T. Dinkova-Kostova The cytoprotective role of the Keap1-Nrf2 pathway Arch. Toxicol. 85 2011 241 272
43. S. Matsushima, S. Kinugawa, T. Ide, H. Matsusaka, N. Inoue, Y. Ohta, T. Yokota, K. Sunagawa, and H. Tsutsui Overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart Am. J. Physiol. Heart Circ. Physiol 291 2006 H2237 H2245
44. D.S. Abdalla, H.P. Monteiro, J.A. Oliveira, and E.J. Bechara Activities of superoxide dismutase and glutathione peroxidase in schizophrenic and manic-depressive patients Clin. Chem. 32 1986 805 807