Both PKA and Epac Pathways Mediate N-Acetylcysteine-Induced Connexin43 Preservation in Rats with Myocardial Infarction

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Lee, Tsung Ming ^a,b,c   Lin, Shinn Zong ^a,b,d,f   Chang, Nen Chung ^c,e  

^a Cardiology Section   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

9 (TETRAHYDRO 2 FURYL)ADENINE; ACETYLCYSTEINE; ANTIPORTER; BREFELDIN A; CONNEXIN 43; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DYE; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP; GLYCOGEN SYNTHASE KINASE 3BETA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARRHYTHMIC SCORE; ARTICLE; COMBINATION CHEMOTHERAPY; CONNEXIN43 GENE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRESSLER SYNDROME; EX VIVO STUDY; GAP JUNCTION; GENE; GENE EXPRESSION; HEART INFARCTION; HEART INFARCTION SIZE; HEART PRESERVATION; HEART PROTECTION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE REMODELING; HEMODYNAMICS; IMMUNOFLUORESCENCE TEST; MALE; MEMBRANE PERMEABILITY; MONOTHERAPY; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; RATING SCALE; REAL TIME POLYMERASE CHAIN REACTION; SCORING SYSTEM; SHAM PROCEDURE; SIGNAL TRANSDUCTION; TREATMENT DURATION; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; ARRHYTHMIAS, CARDIAC; BREFELDIN A; CARDIOTONIC AGENTS; CONNEXIN 43; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG EVALUATION, PRECLINICAL; FREE RADICAL SCAVENGERS; GAP JUNCTIONS; GENE EXPRESSION; GLYCOGEN SYNTHASE KINASE 3; GUANINE NUCLEOTIDE EXCHANGE FACTORS; ISOQUINOLINES; MALE; MYOCARDIAL INFARCTION; PERMEABILITY; PROTEIN KINASE INHIBITORS; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, WISTAR; SULFONAMIDES; VENTRICULAR REMODELING;

EID: 84883162994     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071878     Document Type: Article

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