Single episode of mild murine malaria induces neuroinflammation, alters microglial profile, impairs adult neurogenesis, and causes deficits in social and anxiety-like behavior

Brain, Behavior, and Immunity

Volumn 42, Issue , 2014, Pages 123-137

  Guha, Suman K ^a   Tillu, Rucha ^a   Sood, Ankit ^a   Patgaonkar, Mandar ^a   Nanavaty, Ishira N ^a   Sengupta, Arjun ^a,b   Sharma, Shobhona ^a   Vaidya, Vidita A ^a   Pathak, Sulabha ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cytokine; Doublecortin; Hippocampus; Infection; Neural stem cell; Neuroimmune; Open field test; Plasmodium

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN MALARIA; CALCIUM BINDING; CELL COUNTING; CELL SURVIVAL; CEREBROVASCULAR DISEASE; COMPUTER LANGUAGE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOKINE RESPONSE; DNA DENATURATION; FLOW CYTOMETRY; GENE EXPRESSION; HIPPOCAMPUS; HYDROLYSIS; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; MALARIA; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM INFLAMMATION; NEURAL STEM CELL; NONHUMAN; OPEN FIELD TEST; PARASITE CLEARANCE; PARASITEMIA; PLASMODIUM; PLASMODIUM CHABAUDI; POST HOC ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; QUALITY CONTROL; REAL TIME POLYMERASE CHAIN REACTION; RODENT MALARIA; SOCIAL BEHAVIOR; ANIMAL; ANIMAL BEHAVIOR; BRAIN; COMPLICATION; INFLAMMATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; HIPPOCAMPUS; INFLAMMATION; MALARIA; MALE; MICE; MICROGLIA; NEUROGENESIS; SOCIAL BEHAVIOR;

EID: 84908621420     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.06.009     Document Type: Article

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