Somatic and axonal LIGHT signaling elicit degenerative and regenerative responses in motoneurons, respectively

EMBO Reports

Volumn 15, Issue 5, 2014, Pages 540-547

  Otsmane, Belkacem ^a   Moumen, Anice ^a   Aebischer, Julianne ^a,b   Coque, Emmanuelle ^c   Sar, Chamroeun ^c   Sunyach, Claire ^a   Salsac, Céline ^c   Valmier, Jean ^c   Salinas, Sara ^d   Bowerman, Melissa ^c   Raoul, Cédric ^a,c  

^a Turing Center for Living Systems CENTURI Aix Marseille University   (France)

^b EPFL   (Switzerland)

^c HÔPITAL SAINT ELOI   (France)

^d INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

Author keywords

axon outgrowth; branching; cell death; LIGHT; motoneuron

Indexed keywords

ACTIN; CASPASE 3; CASPASE 9; GAMMA INTERFERON; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN; MYELIN BASIC PROTEIN; NEUROFILAMENT PROTEIN; NEUROMODULIN; PROTEIN LIGHT; PROTEIN P42; PROTEIN P44; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; WHEAT GERM AGGLUTININ; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; CASPASE INHIBITOR; FLAVONOID; HERPESVIRUS ENTRY MEDIATOR LIGAND; LYMPHOTOXIN BETA RECEPTOR; NITRILE; PROTEIN KINASE INHIBITOR; RECOMBINANT PROTEIN; TNFSF14 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL INVASION; CONTROLLED STUDY; EMBRYO; GENE DELETION; GENOTYPE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPHOCYTIC INFILTRATION; MOTONEURON; MOUSE; NERVE CRUSH; NERVE DEGENERATION; NERVE ELONGATION; NERVE FIBER; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE FUNCTION; NERVE LESION; NERVE REGENERATION; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REINNERVATION; SIGNAL TRANSDUCTION; SYNAPTOSOME; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL PROLIFERATION; GENETICS; IMMUNOLOGY; INJURIES; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SCIATIC NERVE;

ANIMALS; AXONS; B-LYMPHOCYTES; BUTADIENES; CASPASE 9; CASPASE INHIBITORS; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; LYMPHOTOXIN BETA RECEPTOR; MICE; MICE, KNOCKOUT; MOTOR NEURONS; NITRILES; PROTEIN KINASE INHIBITORS; RECOMBINANT PROTEINS; SCIATIC NERVE; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14;

EID: 84899790868     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1002/embr.201337948     Document Type: Article

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