Carbon monoxide is not always a poison gas for human organism: Physiological and pharmacological features of CO

Chemico-Biological Interactions

Volumn 222, Issue , 2014, Pages 37-43

  Olas, Beata ^a  

^a UNIVERSITY OF LODZ   (Poland)

Author keywords

Blood platelet; Carbon monoxide; Cardiovascular system

Indexed keywords

CARBON MONOXIDE; CYCLIN DEPENDENT KINASE 2; GUANYLATE CYCLASE; HEME OXYGENASE 1; HEME OXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; GASOTRANSMITTER; HEME;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY THROMBOSIS; BIOLOGICAL ACTIVITY; BIOSYNTHESIS; CARBON METABOLISM; CARDIOVASCULAR SYSTEM; CELL PROTECTION; DRUG PROTEIN BINDING; DRUG RESEARCH; ENZYME ACTIVATION; ENZYME BINDING; ENZYME REGULATION; ENZYME SYNTHESIS; GAS ANALYSIS; GAS EVOLUTION; HEART PROTECTION; HUMAN; IN VIVO STUDY; NERVOUS SYSTEM; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; SHORT SURVEY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE RELAXATION; SYSTEMS BIOLOGY; THROMBOCYTE AGGREGATION INHIBITION; TRANSCRIPTION REGULATION; UPREGULATION; CARDIOVASCULAR FUNCTION; DRUG EFFECTS; METABOLISM; NERVOUS SYSTEM FUNCTION; PHYSIOLOGY;

CARBON MONOXIDE; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; GASOTRANSMITTERS; HEME; HUMANS; NERVOUS SYSTEM PHYSIOLOGICAL PHENOMENA; SIGNAL TRANSDUCTION;

EID: 84908505461     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.08.005     Document Type: Review

References (65)

1. U. Schatzschneider, Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs), Br. J. Pharmacol. (2014) (in press).
2. R.F. Coburn, W.S. Blakemore, R.E. Forester, Endogenous carbon monoxide production in man, J. Clin. Invest. 42 (1963) 1172-1178.
3. H.P. Kim, S.W. Ryter, A.M.K. Choi, CO as a cellular signaling molecule, Annu. Rev. Pharmacol. Toxicol. 46 (2006) 411-449.
4. C.A. Piantadosi, Carbon monoxide, reactive oxygen signaling, and oxidative stress, Free Radic. Biol. Med. 45 (2008) 562-569.
5. L. Wu, R. Wang, Carbon monoxide: endogenous production, physiological functions, and pharmacological applications, Pharmacol. Rev. 57 (2005) 585-630.
6. L. Muchova, R.J. Wong, M. Hsu, I. Morioka, L. Vitek, J. Zelenka, et al., Statin treatment increases formation of carbon monoxide and bilirubin in mice: a novel mechanisms of in vivo antioxidant protection, Can. J. Physiol. Pharmacol. 85 (2007) 800-810.
7. I. Andreadou, E.K. IIiodromitis, T. Rassaf, R. Schulz, A. Papepetropoulos, P. Ferdinandy, The role of gasotransmitters NO, H2S, CO in myocardial ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote conditioning, Br. J. Pharmacol. (2014) (in press).
8. M. Bilban, A. Haschemi, B. Wegiel, B.Y. Chin, O. Wagner, L.E. Otterbein, Heme oxygenase and carbon monoxide initiate homeostatic signaling, J. Mol. Med. 86 (2008) 267-279.
9. M. Ufnal, T. Żera, The role of nitric oxide, hydrogen sulfide and carbon monoxide in the regulation of the circulatory system and their pharmacotherapeutic potential, Pol. Heart J. 5 (2010) 436-440.
10. J.M. Fukuto, S.J. Carrington, D.J. Tantillo, J.G. Harrison, L.J. Ignarro, B.A. Freeman, A. Chen, D.A. Wink, Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species, Chem. Res. Toxicol. 25 (2012) 7690793.
11. J. Tadeusiewicz, B. Olas, Nitric oxide and carbon monoxide as two important gasotransmitters, Kosmos (in press).
12. + channel Nav1.5 by carbon monoxide, JBC (2014) 1-19 (in press).
13. C. Peers, D.S. Steele, Carbon monoxide: a vital signaling molecule and potent toxin in the myocardium, J. Mol. Cell. Cardiol. 52 (2012) 359-365.
14. L.E. Otterbein, A.M.K. Choi, Heme oxygenase: colors of defense against cellular stress, Am. J. Physiol. Lung Cell. Mol. Physiol. 279 (2000) L1029-L1037.
15. J. Bełtowski, A. Jamroz, E. Borkowska, Heme oxygenase and carbon monoxide in the physiology and pathology of the cardiovascular system, Postepy Hig. Med. Dosw. 58 (2004) 83-99.
16. J. Du, Y. Hui, Y. Cheung, G. Ben, H. Jiang, X. Chen, C. Tang, The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells, Heart Vessels 19 (2004) 75-80.
17. G.S. Oh, H.O. Pae, B.S. Lee, B.N. Kim, J.M. Kim, H.R. Kim, S.B. Jeon, W.K. Jeon, H.J. Chae, H.T. Chung, Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide, Free Radic. Biol. Med. 41 (2006) 106-119.
18. S.O. Jeong, H.O. Pae, G.S. Oh, G.S. Jeong, B.S. Lee, S. Lee, d.Y. Kim, H.Y. Rhew, K.M. Lee, H.T. Chung, Hydrogen sulfide potentiates interleukin-1beta-induced nitric oxide production via enhancement of extracellular signal-regulated kinase activation in rat vascular smooth muscle cells, Biochem. Biophys. Res. Commun. 345 (2006) 938-944.
19. B. Olas, Hydrogen sulfide on hemostasis: friend or foe?, Chem Biol. Interact. 217 (2014) 49-56.
20. D. Boehning, Ch. Moon, S. Sharma, K.J. Hurt, L.D. Hester, G.V. Ronnett, D. Shugar, S.H. Snyder, Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2, Neuron 40 (2003) 129-137.
21. W.K. Mccoubrey, T.J. Huang, M.D. Maines, Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3, Eur. J. Biochem. 247 (1997) 725-732.
22. W. Durante, F.K. Johnson, R.A. Johnson, Role of carbon monoxide in cardiovascular function, J. Cell Mol. Med. 10 (2006) 672-686.
23. K. Jasnos, M. Magierowski, S. Kwiecień, T. Brzozowski, Carbon monoxide in human physiology - its role in the gastrointestinal tract, Postepy Hig. Med. Dosw. 68 (2014) 101-109.
24. T.L. Poulos, Soluble guanylate cyclase, Curr. Opin. Struct. Biol. 16 (2006) 736-743.
25. E.R. Derbyshire, M.A. Marletta, Structure and regulation of soluble guanylate cyclase, Annu. Rev. Biochem. 81 (2012) 533-559.
26. N. Gupta, S.W. Ragsdale, Thiol-disulfide redox dependence of heme binding and heme ligand switching in nuclear hormone receptor Rev-erbβ, J. Biol. Chem. 286 (2011) 4392-4403.
27. W.J. Wilkinson, P.J. Kemp, Carbon monoxide: an emerging regulator of ion channels, J. Physiol. 589 (2011) 3055-3062.
28. B. Brune, V. Ullrich, Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase, Mol. Pharmacol. 32 (1987) 497-504.
29. S. Chłopicki, R. Olszanecki, E. Marcinkiewicz, M. Łomnicka, R. Motterlini, Carbon monoxide released by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase, Cardiovasc. Res. 71 (2006) 393-401.
30. N.J. Truss, T.D. Warner, Gasotransmitters and platelets, Pharmacol. Ther. 132 (2011) 196-203.
31. S. Li Calzi, D.L. Purich, K.H. Chang, A. Afzal, T. Nakagawa, J.V. Busik, A. Agarwal, M.S. Segal, M.B. Grant, Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetes, Diabetes 57 (2008) 2488-2494.
32. J.G. Vostal, J.C. Fratantoni, Econazole inhibits thapsigargin-induced platelet calcium influx by mechanisms other than cytochrome P-450 inhibition, Biochem. J. 295 (1993) 525-529.
33. L. Peng, L. Mundada, J.M. Stomel, J.J. Liu, J. Sun, S.F. Yet, W.P. Fay, Induction of heme oxygenase-1 expression inhibits platelet-dependent thrombosis, Antioxid. Redox Signal. 6 (2004) 729-735.
34. N. Desbuards, G.Y. Rochefort, D. Schlecht, M.C. Machet, J.M. Halimi, V. Eder, J.M. Hyvelin, D. Antier, Heme oxygenase-1 inducer hemin prevents vascular thrombosis, Thromb. Haemost. 98 (2007) 614-620.
35. B. Chen, L. Guo, C. Fan, S. Bolisetty, R. Joseph, M.M. Wright, A. Agarwal, J.F. George, Carbon monoxide rescues heme oxygenase-1-deficient mice from arterial thrombosis in allogeneic aortic transplantation, Am. J. Pathol. 175 (2009) 422-429.
36. Y.H. Chen, H.L. Tsai, M.T. Chiang, L.Y. Chau, Carbon monoxide-induced early thrombolysis contributes to heme oxygenase-1-mediated inhibition of neointimal growth after vascular injury in hypercholesterolemic mice, J. Biomed. Sci. 13 (2006) 721-730.
37. H.J. Duckers, M. Boehm, A.L. True, S.F. Yet, H. San, J.L. Park, Heme oxygenase-1 protects against vascular constriction and proliferation, Nat. Med. 7 (2001) 693-698.
38. L.E. Otterbein, F.H. Bach, J. Alam, M. Soaries, H.T. Lu, M. Wysk, R.J. Davis, R.A. Flavell, A.M.K. Choi, Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway, Nat. Med. 6 (2000) 422-428.
39. X. Zhang, P. Shan, J. Alam, R.J. Davis, R.A. Flavell, P.J. Lee, Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38α mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury, J. Biol. Chem. 278 (2003) 22061-22070.
40. X. Liu, G.B. Chapman, K.J. Peyton, A.I. Schafer, W. Durante, Carbon monoxide inhibits apoptosis in vascular smooth muscle cells, Cardiovasc. Res. 55 (2002) 396-405.
41. S. Brouard, L.E. Otterbein, J. Anrather, E. Tobiasch, F.H. Bach, A.M.K. Choi, M.P. Soares, Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis, J. Exp. Med. 192 (2000) 1015-1025.
42. 2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species, J. Biol. Chem. 283 (2008) 24412-24419.
43. Ch. Peers, M.L. Dallas, J.L. Scragg, Ion channels as effectors in carbon monoxide signaling, Commun. Integr. Biol. 2 (2009) 241-242.
44. P. Lakkisto, E. Palojoki, T. Backlund, A. Saraste, I. Tikkanan, L.M. Voipio-Pulkki, K. Pulkki, Expression of heme oxygenase-1 in response to myocardial infarction in rats, J. Mol. Cell. Cardiol. 34 (2002) 1357-1365.
45. J.E. Clark, P. Naughton, S. Shurey, C.J. Green, T.R. Johnson, B.E. Mann, R. Foresti, R. Motterlini, Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule, Circ. Res. 93 (2003) e2-e8.
46. S.F. Yet, M.A. Perrella, M.D. Layne, C.M. Hsieh, K. Maemura, L. Kobzik, P. Wiesel, H. Christou, S. Kourembana, M.E. Lee, Hypoxia induces severe right ventricular dilatation and infraction in heme oxygenase-1 null mice, J. Clin. Invest. 103 (1999) R23-R29.
47. S.F. Yet, R. Tian, M.D. Layne, Z.Y. Wang, K. Maemura, M. Solovyeva, B. Ith, L.G. Melo, L. Zhang, J.S. Ingwall, V.J. Dzau, M.E. Lee, M.A. Perrella, Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice, Circ. Res. 89 (2001) 168-173.
48. Y.S. Jung, J.S. Lee, Y.G. Min, J.S. Park, W.C. Jeon, E.J. Park, J.H. Shin, S. Oh, S.C. Choi, Carbon monoxide-induced cardiomyopathy-epidemiology, clinical characteristics and prognosis, Circ. J. (2014) 1-8 (in press).
49. V.L. Mahan, Neuroprotective, neurotherapeutic, and neurometabolic effects of carbon monoxide, Med. Gas Res. 2 (2012) 1-7.
50. H.S. Kim, P.A. Loughran, T.R. Billiar, Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1b-stimulated hepatocytes, Nitric Oxide 18 (2008) 256-265.
51. Y. Liu, Z. Li, X Shi, Y. Liu, W. Li, G. Duan, H. Li, X. Yang, C. Zhang, L. Zou, Neuroprotection of up-regulated carbon monoxide by electrical acupuncture on perinatal hypoxic-ischemic brain damage in rats, Neurochem. Res. (2014) (in press).
52. K.A. Nath, Preservation of the kidney by carbon monoxide: a black swan phenomenon, Kidney Int. 74 (2008) 989-991.
53. E. Chan, G.J. Dusting, G.S. Liu, F. Jiang, Redox mechanisms of the beneficial effects of heme oxygenase in hypertension, J. Hypertension. 32 (2014) 1379-1386.
54. O. Kreß, M. Gnida, A.M. Pelzmann, C. Marx, W. Meyer-Klaucke, O. Meyer, Reversible inactivation of CO dehydrogenase with thiol compounds, Biochem. Biophys. Res. Commun. 447 (2014) 413-418.
55. N. Arngrim, H.W. Schytz, M.K. Hauge, M. Ashina, J. Olesen, Carbon monoxide may be an important molecule in migraine and other headaches, Cephalalgia (2014) (in press).
56. H. Yin, J. Fang, L. Liao, H. Maeda, Q. Su, Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity, BMC Cancer 14 (2014) 436-441.
57. B. Sun, X. Zou, Y. Chen, P. Zhang, G. Shi, Preconditioning of carbon monoxide releasing molecule-derived CO attenuates LPS-induced activation of HUVEC, Int. J. Biol. Sci. 4 (2008) 270-278.
58. A.B. Stein, Y. Guo, W. Tan, W.J. Wu, X. Zhu, Q. Liu, et al., Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction, J. Moll. Cell. Cardiol. 38 (2005) 127-134.
59. Y. Ruan, L., Wang, Y. Zhao, Y. Yao, S. Chen, J. Li, H. Guo, C. Ming, S. Chen, F. Gong, G. Chen, Carbon monoxide potently prevents ischemia-induced high-mobility group box 1 translocation and release and protects against lethal renal ischemia-reperfusion injury, Kidney Int. (2014) (in press).
60. B. Bakhautdin, D. Das, P. Mandal, S. Roychowdhury, J. Danner, K. Bush, K. Pollard, J.W. Kaspar, W. Li, R.G. Salomon, M.R. McMullen, L.E. Nagy, Protective role of HO-1 and carbon monoxide in ethanol-induced cell death in hepatocytes and liver injury in mice, J. Hepatol. (2014) (in press).
61. C. Steiger, T. Luhmann, L. Meinel, Oral drug delivery of therapeutic gases - carbon monoxide release for gastrointestinal diseases, J. Control. Release 189 (2014) 46-53.
62. B.E. Mann, Carbon monoxide: an essential signalling molecule, in: N. Metzler-Nolte, G. Jaouen (Eds.), Top. Organomet. Chem., vol. 32, Springer, Berlin, 2010, pp. 247-285.
63. C.C. Romao, W.A. Blattler, J.D. Seixas, G.J.L. Bernardes, Developing drug molecules for therapy with carbon monoxide, Chem. Soc. Rev. 41 (2012) 3571-3583.
64. H.H. Lin, Y.H. Chen, M.T. Chiang, P.L. Huang, L.Y. Chau, Activator protein-2 mediates carbon monoxide-induced stromal cell-derived factor-1 expression and vascularization in ischemic heart, Arterioscler. Thromb. Vasc. Biol. 33 (2013) 785-794.
65. H.M. Soni, M.R. Jain, A.A. Mehta, Mechanism(s) involved in carbon monoxide-releasing molecule-2-mediated cardioprotection during ischemia-reperfusion injury in isolated rat heart, Indian J. Pharm. Sci. 74 (2012) 281-291.