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Volumn 12, Issue 11, 2014, Pages 1537-1545

Solid malignancies in individuals with down syndrome: A case presentation and literature review

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; DOCETAXEL; DOXORUBICIN; TAMOXIFEN; TRASTUZUMAB;

EID: 84908500980     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2014.0153     Document Type: Article
Times cited : (8)

References (78)
  • 1
    • 12944293058 scopus 로고    scopus 로고
    • Changing demographics of advanced maternal age (AMA) and the impact on the predicted incidence of Down syndrome in the United States: Implications for prenatal screening and genetic counseling
    • Resta RG. Changing demographics of advanced maternal age (AMA) and the impact on the predicted incidence of Down syndrome in the United States: implications for prenatal screening and genetic counseling. Am J Med Genet A 2005; 133A: 31-36.
    • (2005) Am J Med Genet A , vol.133 A , pp. 31-36
    • Resta, R.G.1
  • 2
    • 0342905433 scopus 로고    scopus 로고
    • Risks of leukaemia and solid tumours in individuals with Down's syndrome
    • Hasle H, Clemmensen IH, Mikkelsen M. Risks of leukaemia and solid tumours in individuals with Down's syndrome. Lancet 2000; 355: 165-169.
    • (2000) Lancet , vol.355 , pp. 165-169
    • Hasle, H.1    Clemmensen, I.H.2    Mikkelsen, M.3
  • 3
    • 0037160991 scopus 로고    scopus 로고
    • Mortality associated with Down's syndrome in the USA from 1983 to 1997: A population-based study
    • Yang Q, Rasmussen SA, Friedman JM. Mortality associated with Down's syndrome in the USA from 1983 to 1997: a population-based study. Lancet 2002; 359: 1019-1025.
    • (2002) Lancet , vol.359 , pp. 1019-1025
    • Yang, Q.1    Rasmussen, S.A.2    Friedman, J.M.3
  • 4
    • 0344837278 scopus 로고    scopus 로고
    • The changing survival profile of people with Down's syndrome: Implications for genetic counselling
    • Glasson EJ, Sullivan SG, Hussain R, et al. The changing survival profile of people with Down's syndrome: implications for genetic counselling. Clin Genet 2002; 62: 390-393.
    • (2002) Clin Genet , vol.62 , pp. 390-393
    • Glasson, E.J.1    Sullivan, S.G.2    Hussain, R.3
  • 5
    • 0035023396 scopus 로고    scopus 로고
    • Mortality and cancer incidence in persons with Down's syndrome, their parents and siblings
    • Hermon C, Alberman E, Beral V, Swerdlow AJ. Mortality and cancer incidence in persons with Down's syndrome, their parents and siblings. Ann Hum Genet 2001; 65(Pt 2): 167-176.
    • (2001) Ann Hum Genet , vol.65 , pp. 167-176
    • Hermon, C.1    Alberman, E.2    Beral, V.3    Swerdlow, A.J.4
  • 6
    • 38649095184 scopus 로고    scopus 로고
    • Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: A report from the Children's Oncology Group Study POG 9421
    • O'Brien MM, Taub JW, Chang MN, et al. Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: a report from the Children's Oncology Group Study POG 9421. J Clin Oncol 2008; 26: 414-420.
    • (2008) J Clin Oncol , vol.26 , pp. 414-420
    • O'brien, M.M.1    Taub, J.W.2    Chang, M.N.3
  • 7
    • 79953789925 scopus 로고    scopus 로고
    • Use of tamoxifen with postsurgical irradiation may improve survival in estrogen and progesterone receptorpositive male breast cancer
    • Fogh S, Hirsch AE, Langmead JP, et al. Use of tamoxifen with postsurgical irradiation may improve survival in estrogen and progesterone receptorpositive male breast cancer. Clin Breast Cancer 2011; 11: 39-45.
    • (2011) Clin Breast Cancer , vol.11 , pp. 39-45
    • Fogh, S.1    Hirsch, A.E.2    Langmead, J.P.3
  • 9
    • 81755172142 scopus 로고    scopus 로고
    • Incidence and outcome of male breast cancer: An international population-based study
    • Miao H, Verkooijen HM, Chia KS, et al. Incidence and outcome of male breast cancer: an international population-based study. J Clin Oncol 2011; 29: 4381-4386.
    • (2011) J Clin Oncol , vol.29 , pp. 4381-4386
    • Miao, H.1    Verkooijen, H.M.2    Chia, K.S.3
  • 10
    • 84862519426 scopus 로고    scopus 로고
    • Evolving trends in the initial locoregional management of male breast cancer
    • Bratman SV, Kapp DS, Horst KC. Evolving trends in the initial locoregional management of male breast cancer. Breast 2012; 21: 296-302.
    • (2012) Breast , vol.21 , pp. 296-302
    • Bratman, S.V.1    Kapp, D.S.2    Horst, K.C.3
  • 11
    • 79958281904 scopus 로고    scopus 로고
    • Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer
    • Callari M, Cappelletti V, De Cecco L, et al. Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer. Breast Cancer Res Treat 2010; 127: 601-610.
    • (2010) Breast Cancer Res Treat , vol.127 , pp. 601-610
    • Callari, M.1    Cappelletti, V.2    De Cecco, L.3
  • 12
    • 80052564919 scopus 로고    scopus 로고
    • High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer
    • Johansson I, Nilsson C, Berglund P, et al. High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer. Breast Cancer Res Treat 2010; 129: 747-760.
    • (2010) Breast Cancer Res Treat , vol.129 , pp. 747-760
    • Johansson, I.1    Nilsson, C.2    Berglund, P.3
  • 13
    • 70349581484 scopus 로고    scopus 로고
    • BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: A population-based study in central Italy
    • Ottini L, Rizzolo P, Zanna I, et al. BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy. Breast Cancer Res Treat 2009; 116: 577-586.
    • (2009) Breast Cancer Res Treat , vol.116 , pp. 577-586
    • Ottini, L.1    Rizzolo, P.2    Zanna, I.3
  • 14
  • 15
    • 64149129804 scopus 로고    scopus 로고
    • Malignancy in children with trisomy 21
    • Rabin KR, Whitlock JA. Malignancy in children with trisomy 21. Oncologist 2009; 14: 164-173.
    • (2009) Oncologist , vol.14 , pp. 164-173
    • Rabin, K.R.1    Whitlock, J.A.2
  • 16
    • 84872060888 scopus 로고    scopus 로고
    • Survival among people with Down syndrome: A nationwide population-based study in Denmark
    • Zhu JL, Hasle H, Correa A, et al. Survival among people with Down syndrome: a nationwide population-based study in Denmark. Genet Med 2013; 15: 64-69.
    • (2013) Genet Med , vol.15 , pp. 64-69
    • Zhu, J.L.1    Hasle, H.2    Correa, A.3
  • 17
    • 33644872564 scopus 로고    scopus 로고
    • Cancer incidence of persons with Down syndrome in Finland: A population-based study
    • Patja K, Pukkala E, Sund R, et al. Cancer incidence of persons with Down syndrome in Finland: a population-based study. Int J Cancer 2006; 118: 1769-1772.
    • (2006) Int J Cancer , vol.118 , pp. 1769-1772
    • Patja, K.1    Pukkala, E.2    Sund, R.3
  • 19
    • 0037463857 scopus 로고    scopus 로고
    • Mortality and cancer incidence among individuals with Down syndrome
    • Hill DA, Gridley G, Cnattingius S, et al. Mortality and cancer incidence among individuals with Down syndrome. Arch Intern Med 2003; 163: 705-711.
    • (2003) Arch Intern Med , vol.163 , pp. 705-711
    • Hill, D.A.1    Gridley, G.2    Cnattingius, S.3
  • 20
    • 84866735729 scopus 로고    scopus 로고
    • Tumorigenesis in Down's syndrome: Big lessons from a small chromosome
    • Nizetic D, Groet J. Tumorigenesis in Down's syndrome: big lessons from a small chromosome. Nat Rev Cancer 2012; 12: 721-732.
    • (2012) Nat Rev Cancer , vol.12 , pp. 721-732
    • Nizetic, D.1    Groet, J.2
  • 21
    • 0035452428 scopus 로고    scopus 로고
    • Incidence of leukemia and other cancers in Down syndrome subjects in Israel
    • Boker LK, Blumstein T, Sadetzki S, et al. Incidence of leukemia and other cancers in Down syndrome subjects in Israel. Int J Cancer 2001; 93: 741-744.
    • (2001) Int J Cancer , vol.93 , pp. 741-744
    • Boker, L.K.1    Blumstein, T.2    Sadetzki, S.3
  • 22
  • 23
    • 7944222395 scopus 로고    scopus 로고
    • Cancers and immune related diseases associated with Down's syndrome: A record linkage study
    • Goldacre MJ, Wotton CJ, Seagroatt V, Yeates D. Cancers and immune related diseases associated with Down's syndrome: a record linkage study. Arch Dis Child 2004; 89: 1014-1017.
    • (2004) Arch Dis Child , vol.89 , pp. 1014-1017
    • Goldacre, M.J.1    Wotton, C.J.2    Seagroatt, V.3    Yeates, D.4
  • 24
    • 84966151860 scopus 로고
    • The mortality from leukaemia and other cancers among patients with Down's syndrome (mongols) and among their parents
    • Holland WW, Doll R, Carter CO. The mortality from leukaemia and other cancers among patients with Down's syndrome (mongols) and among their parents. Br J Cancer 1962; 16: 177-186.
    • (1962) Br J Cancer , vol.16 , pp. 177-186
    • Holland, W.W.1    Doll, R.2    Carter, C.O.3
  • 25
    • 0020466620 scopus 로고
    • Leukemia and other cancers, anomalies and infections as causes of death in Down's syndrome in the United States during 1976
    • Scholl T, Stein Z, Hansen H. Leukemia and other cancers, anomalies and infections as causes of death in Down's syndrome in the United States during 1976. Dev Med Child Neurol 1982; 24: 817-829.
    • (1982) Dev Med Child Neurol , vol.24 , pp. 817-829
    • Scholl, T.1    Stein, Z.2    Hansen, H.3
  • 26
    • 0346977278 scopus 로고    scopus 로고
    • Breast cancer in women with trisomy 21 [in French]
    • discussion 1252-1254
    • Satge D, Sasco AJ, Pujol H, Rethore MO. Breast cancer in women with trisomy 21 [in French]. Bull Acad Natl Med 2001; 185: 1239-1252; discussion 1252-1254.
    • (2001) Bull Acad Natl Med , vol.185 , pp. 1239-1252
    • Satge, D.1    Sasco, A.J.2    Pujol, H.3    Rethore, M.O.4
  • 27
    • 79551647855 scopus 로고    scopus 로고
    • Benign and malignant tumors in Down syndrome: Analysis of the 1514 autopsied cases in Japan
    • Ehara H, Ohno K, Ito H. Benign and malignant tumors in Down syndrome: analysis of the 1514 autopsied cases in Japan. Pediatr Int 2011; 53: 72-77.
    • (2011) Pediatr Int , vol.53 , pp. 72-77
    • Ehara, H.1    Ohno, K.2    Ito, H.3
  • 28
    • 84890887380 scopus 로고    scopus 로고
    • Adenocarcinoma of the lung in Down syndrome: First clinical report
    • Satge D, Salmeron S, Homsi T, et al. Adenocarcinoma of the lung in Down syndrome: first clinical report. Tumori 2013; 99: e169-171.
    • (2013) Tumori , vol.99 , pp. e169-171
    • Satge, D.1    Salmeron, S.2    Homsi, T.3
  • 29
    • 0030829046 scopus 로고    scopus 로고
    • Medical aspects of ageing in a population with intellectual disability: III. Mobility internal conditions and cancer
    • Evenhuis HM. Medical aspects of ageing in a population with intellectual disability: III. Mobility, internal conditions and cancer. J Intellect Disabil Res 1997; 41(Pt 1): 8-18.
    • (1997) J Intellect Disabil Res , vol.41 , pp. 8-18
    • Evenhuis, H.M.1
  • 30
    • 34248226368 scopus 로고    scopus 로고
    • Use of health care guidelines in patients with Down syndrome by family physicians across Canada
    • Virji-Babul N, Eichmann A, Kisly D, et al. Use of health care guidelines in patients with Down syndrome by family physicians across Canada. Paediatr Child Health 2007; 12: 179-183.
    • (2007) Paediatr Child Health , vol.12 , pp. 179-183
    • Virji-Babul, N.1    Eichmann, A.2    Kisly, D.3
  • 31
    • 0037062119 scopus 로고    scopus 로고
    • Breast screening guidelines should be adapted in Down's syndrome
    • Satgé D, Sasco AJ. Breast screening guidelines should be adapted in Down's syndrome. BMJ. 2002; 324: 1155.
    • (2002) BMJ , vol.324 , pp. 1155
    • Satgé, D.1    Sasco, A.J.2
  • 32
    • 1942457411 scopus 로고    scopus 로고
    • The importance of smoking education and preventative health strategies for people with intellectual disability
    • Tracy J, Hosken R. The importance of smoking education and preventative health strategies for people with intellectual disability. J Intellect Disabil Res 1997; 41(Pt 5): 416-421.
    • (1997) J Intellect Disabil Res , vol.41 , pp. 416-421
    • Tracy, J.1    Hosken, R.2
  • 33
    • 0034900991 scopus 로고    scopus 로고
    • Cancer incidence among people with intellectual disability
    • Patja K, Eero P, Iivanainen M. Cancer incidence among people with intellectual disability. J Intellect Disabil Res 2001; 45(Pt 4): 300-307.
    • (2001) J Intellect Disabil Res , vol.45 , pp. 300-307
    • Patja, K.1    Eero, P.2    Iivanainen, M.3
  • 36
    • 43149119494 scopus 로고    scopus 로고
    • Environmental and occupational causes of cancer: New evidence 2005-2007
    • Clapp RW, Jacobs MM, Loechler EL. Environmental and occupational causes of cancer: new evidence 2005-2007. Rev Environ Health 2008; 23: 1-37.
    • (2008) Rev Environ Health , vol.23 , pp. 1-37
    • Clapp, R.W.1    Jacobs, M.M.2    Loechler, E.L.3
  • 37
    • 0037049927 scopus 로고    scopus 로고
    • Bone mass, gonadal function and biochemical assessment in young men with trisomy 21
    • Sakadamis A, Angelopoulou N, Matziari C, et al. Bone mass, gonadal function and biochemical assessment in young men with trisomy 21. Eur J Obstet Gynecol Reprod Biol 2002; 100: 208-212.
    • (2002) Eur J Obstet Gynecol Reprod Biol , vol.100 , pp. 208-212
    • Sakadamis, A.1    Angelopoulou, N.2    Matziari, C.3
  • 39
    • 0023273462 scopus 로고
    • Gonadal function in patients with Down syndrome
    • Hsiang YH, Berkovitz GD, Bland GL, et al. Gonadal function in patients with Down syndrome. Am J Med Genet 1987; 27: 449-458.
    • (1987) Am J Med Genet , vol.27 , pp. 449-458
    • Hsiang, Y.H.1    Berkovitz, G.D.2    Bland, G.L.3
  • 40
    • 19944428648 scopus 로고    scopus 로고
    • Childhood and maternal infections and risk of acute leukaemia in children with Down syndrome: A report from the Children's Oncology Group
    • Canfield KN, Spector LG, Robison LL, et al. Childhood and maternal infections and risk of acute leukaemia in children with Down syndrome: a report from the Children's Oncology Group. Br J Cancer 2004; 91: 1866-1872.
    • (2004) Br J Cancer , vol.91 , pp. 1866-1872
    • Canfield, K.N.1    Spector, L.G.2    Robison, L.L.3
  • 41
    • 84884176276 scopus 로고    scopus 로고
    • Allergy and acute leukaemia in children with Down syndrome: A population study. Report from the Mexican inter-institutional group for the identification of the causes of childhood leukaemia
    • Nunez-Enriquez JC, Fajardo-Gutierrez A, Buchan-Duran EP, et al. Allergy and acute leukaemia in children with Down syndrome: a population study. Report from the Mexican inter-institutional group for the identification of the causes of childhood leukaemia. Br J Cancer 2013; 108: 2334-2338.
    • (2013) Br J Cancer , vol.108 , pp. 2334-2338
    • Nunez-Enriquez, J.C.1    Fajardo-Gutierrez, A.2    Buchan-Duran, E.P.3
  • 42
    • 70249089093 scopus 로고    scopus 로고
    • Breastfeeding and early infection in the aetiology of childhood leukaemia in Down syndrome
    • Flores-Lujano J, Perez-Saldivar ML, Fuentes-Panana EM, et al. Breastfeeding and early infection in the aetiology of childhood leukaemia in Down syndrome. Br J Cancer 2009; 101(5): 860-864.
    • (2009) Br J Cancer , vol.101 , Issue.5 , pp. 860-864
    • Flores-Lujano, J.1    Perez-Saldivar, M.L.2    Fuentes-Panana, E.M.3
  • 43
    • 42249101930 scopus 로고    scopus 로고
    • Vitamin supplement use among children with Down's syndrome and risk of leukaemia: A Children's Oncology Group (COG) study
    • Blair CK, Roesler M, Xie Y, et al. Vitamin supplement use among children with Down's syndrome and risk of leukaemia: a Children's Oncology Group (COG) study. Paediatr Perinat Epidemiol 2008; 22: 288-295.
    • (2008) Paediatr Perinat Epidemiol , vol.22 , pp. 288-295
    • Blair, C.K.1    Roesler, M.2    Xie, Y.3
  • 44
    • 22244448021 scopus 로고    scopus 로고
    • Periconceptional vitamin use and leukemia risk in children with Down syndrome: A Children's Oncology Group study
    • Ross JA, Blair CK, Olshan AF, et al. Periconceptional vitamin use and leukemia risk in children with Down syndrome: a Children's Oncology Group study. Cancer 2005; 104: 405-410.
    • (2005) Cancer , vol.104 , pp. 405-410
    • Ross, J.A.1    Blair, C.K.2    Olshan, A.F.3
  • 45
    • 84876592083 scopus 로고    scopus 로고
    • A genomic view of mosaicism and human disease
    • Biesecker LG, Spinner NB. A genomic view of mosaicism and human disease. Nat Rev Genet 2013; 14: 307-320.
    • (2013) Nat Rev Genet , vol.14 , pp. 307-320
    • Biesecker, L.G.1    Spinner, N.B.2
  • 46
    • 0038575240 scopus 로고    scopus 로고
    • Down syndrome: A study of chromosomal mosaicism
    • Modi D, Berde P, Bhartiya D. Down syndrome: a study of chromosomal mosaicism. Reprod Biomed Online 2003; 6: 499-503.
    • (2003) Reprod Biomed Online , vol.6 , pp. 499-503
    • Modi, D.1    Berde, P.2    Bhartiya, D.3
  • 47
    • 0017149482 scopus 로고
    • Comparison of mental development in individuals with mosaic and trisomy 21 Down's syndrome
    • Fishler K, Koch R, Donnell GN. Comparison of mental development in individuals with mosaic and trisomy 21 Down's syndrome. Pediatrics 1976; 58: 744-748.
    • (1976) Pediatrics , vol.58 , pp. 744-748
    • Fishler, K.1    Koch, R.2    Donnell, G.N.3
  • 48
    • 63749094761 scopus 로고    scopus 로고
    • The phenotype of persons having mosaicism for trisomy 21/Down syndrome reflects the percentage of trisomic cells present in different tissues
    • Papavassiliou P, York TP, Gursoy N, et al. The phenotype of persons having mosaicism for trisomy 21/Down syndrome reflects the percentage of trisomic cells present in different tissues. Am J Med Genet A 2009; 149A: 573-583.
    • (2009) Am J Med Genet A , vol.149 A , pp. 573-583
    • Papavassiliou, P.1    York, T.P.2    Gursoy, N.3
  • 49
    • 38049069895 scopus 로고    scopus 로고
    • Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome
    • Sussan TE, Yang A, Li F, et al. Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome. Nature 2008; 451: 73-75.
    • (2008) Nature , vol.451 , pp. 73-75
    • Sussan, T.E.1    Yang, A.2    Li, F.3
  • 50
    • 75149140916 scopus 로고    scopus 로고
    • Mitotic chromosomal instability and cancer: Mouse modelling of the human disease
    • Schvartzman JM, Sotillo R, Benezra R. Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nat Rev Cancer 2010; 10: 102-115.
    • (2010) Nat Rev Cancer , vol.10 , pp. 102-115
    • Schvartzman, J.M.1    Sotillo, R.2    Benezra, R.3
  • 51
    • 63149148209 scopus 로고    scopus 로고
    • Constitutional aneuploidy and cancer predisposition
    • Ganmore I, Smooha G, Izraeli S. Constitutional aneuploidy and cancer predisposition. Hum Mol Genet 2009; 18(R1): R84-93.
    • (2009) Hum Mol Genet , vol.18 , Issue.1 , pp. R84-93
    • Ganmore, I.1    Smooha, G.2    Izraeli, S.3
  • 52
    • 0034682403 scopus 로고    scopus 로고
    • The DNA sequence of human chromosome 21
    • Hattori M, Fujiyama A, Taylor TD, et al. The DNA sequence of human chromosome 21. Nature 2000; 405: 311-319.
    • (2000) Nature , vol.405 , pp. 311-319
    • Hattori, M.1    Fujiyama, A.2    Taylor, T.D.3
  • 53
    • 29444460637 scopus 로고    scopus 로고
    • Further correlations of morphology according to FAB and WHO classification to cytogenetics in de novo acute myeloid leukemia: A study on 2 235 patients
    • Bacher U, Kern W, Schnittger S, et al. Further correlations of morphology according to FAB and WHO classification to cytogenetics in de novo acute myeloid leukemia: a study on 2, 235 patients. Ann Hematol 2005; 84: 785-791.
    • (2005) Ann Hematol , vol.84 , pp. 785-791
    • Bacher, U.1    Kern, W.2    Schnittger, S.3
  • 54
    • 0030901159 scopus 로고    scopus 로고
    • Acute lymphoblastic leukemia and chromosome 21
    • Berger R. Acute lymphoblastic leukemia and chromosome 21. Cancer Genet Cytogenet 1997; 94: 8-12.
    • (1997) Cancer Genet Cytogenet , vol.94 , pp. 8-12
    • Berger, R.1
  • 55
    • 34249065493 scopus 로고    scopus 로고
    • Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia
    • Heerema NA, Raimondi SC, Anderson JR, et al. Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia. Genes Chromosomes Cancer 2007; 46: 684-693.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 684-693
    • Heerema, N.A.1    Raimondi, S.C.2    Anderson, J.R.3
  • 56
    • 63149148538 scopus 로고    scopus 로고
    • Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome
    • Malinge S, Izraeli S, Crispino JD. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood 2009; 113: 2619-2628.
    • (2009) Blood , vol.113 , pp. 2619-2628
    • Malinge, S.1    Izraeli, S.2    Crispino, J.D.3
  • 57
    • 38349119730 scopus 로고    scopus 로고
    • Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome
    • Kirsammer G, Jilani S, Liu H, et al. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood 2008; 111: 767-775.
    • (2008) Blood , vol.111 , pp. 767-775
    • Kirsammer, G.1    Jilani, S.2    Liu, H.3
  • 58
    • 61849124643 scopus 로고    scopus 로고
    • Hematopoietic defects in the Ts1Cje mouse model of Down syndrome
    • Carmichael CL, Majewski IJ, Alexander WS, et al. Hematopoietic defects in the Ts1Cje mouse model of Down syndrome. Blood 2009; 113: 1929-1937.
    • (2009) Blood , vol.113 , pp. 1929-1937
    • Carmichael, C.L.1    Majewski, I.J.2    Alexander, W.S.3
  • 59
    • 77951074754 scopus 로고    scopus 로고
    • Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome
    • Alford KA, Slender A, Vanes L, et al. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. Blood 2010; 115: 2928-2937.
    • (2010) Blood , vol.115 , pp. 2928-2937
    • Alford, K.A.1    Slender, A.2    Vanes, L.3
  • 60
    • 84857814609 scopus 로고    scopus 로고
    • Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome
    • Malinge S, Bliss-Moreau M, Kirsammer G, et al. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest 2012; 122: 948-962.
    • (2012) J Clin Invest , vol.122 , pp. 948-962
    • Malinge, S.1    Bliss-Moreau, M.2    Kirsammer, G.3
  • 61
    • 33646171446 scopus 로고    scopus 로고
    • NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
    • Arron JR, Winslow MM, Polleri A, et al. NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature 2006; 441: 595-600.
    • (2006) Nature , vol.441 , pp. 595-600
    • Arron, J.R.1    Winslow, M.M.2    Polleri, A.3
  • 62
    • 9644262448 scopus 로고    scopus 로고
    • Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis
    • Minami T, Horiuchi K, Miura M, et al. Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. J Biol Chem 2004; 279: 50537-50554.
    • (2004) J Biol Chem , vol.279 , pp. 50537-50554
    • Minami, T.1    Horiuchi, K.2    Miura, M.3
  • 63
    • 67649506317 scopus 로고    scopus 로고
    • Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
    • Baek KH, Zaslavsky A, Lynch RC, et al. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature 2009; 459: 1126-1130.
    • (2009) Nature , vol.459 , pp. 1126-1130
    • Baek, K.H.1    Zaslavsky, A.2    Lynch, R.C.3
  • 64
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277-285.
    • (1997) Cell , vol.88 , pp. 277-285
    • O'reilly, M.S.1    Boehm, T.2    Shing, Y.3
  • 65
    • 77953457835 scopus 로고    scopus 로고
    • Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome
    • Reynolds LE, Watson AR, Baker M, et al. Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. Nature 2010; 465: 813-817.
    • (2010) Nature , vol.465 , pp. 813-817
    • Reynolds, L.E.1    Watson, A.R.2    Baker, M.3
  • 66
    • 0035667067 scopus 로고    scopus 로고
    • High serum endostatin levels in Down syndrome: Implications for improved treatment and prevention of solid tumours
    • Zorick TS, Mustacchi Z, Bando SY, et al. High serum endostatin levels in Down syndrome: implications for improved treatment and prevention of solid tumours. Eur J Hum Genet 2001; 9: 811-814.
    • (2001) Eur J Hum Genet , vol.9 , pp. 811-814
    • Zorick, T.S.1    Mustacchi, Z.2    Bando, S.Y.3
  • 67
    • 33847313222 scopus 로고    scopus 로고
    • Inhibition of breast cancer growth and invasion by single-minded 2s
    • Kwak HI, Gustafson T, Metz RP, et al. Inhibition of breast cancer growth and invasion by single-minded 2s. Carcinogenesis 2007; 28: 259-266.
    • (2007) Carcinogenesis , vol.28 , pp. 259-266
    • Kwak, H.I.1    Gustafson, T.2    Metz, R.P.3
  • 68
    • 40749114019 scopus 로고    scopus 로고
    • The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy
    • Ge Y, LaFiura KM, Dombkowski AA, et al. The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. Leukemia 2008; 22: 521-529.
    • (2008) Leukemia , vol.22 , pp. 521-529
    • Ge, Y.1    Lafiura, K.M.2    Dombkowski, A.A.3
  • 69
    • 0032585844 scopus 로고    scopus 로고
    • The "gene dosage effect" hypothesis versus the "amplified developmental instability" hypothesis in Down syndrome
    • Pritchard MA, Kola I. The "gene dosage effect" hypothesis versus the "amplified developmental instability" hypothesis in Down syndrome. J Neural Transm Suppl 1999; 57: 293-303.
    • (1999) J Neural Transm Suppl , vol.57 , pp. 293-303
    • Pritchard, M.A.1    Kola, I.2
  • 70
    • 84881668417 scopus 로고    scopus 로고
    • Translating dosage compensation to trisomy 21
    • Jiang J, Jing Y, Cost GJ, et al. Translating dosage compensation to trisomy 21. Nature 2013; 500: 296-300.
    • (2013) Nature , vol.500 , pp. 296-300
    • Jiang, J.1    Jing, Y.2    Cost, G.J.3
  • 71
    • 84898945538 scopus 로고    scopus 로고
    • Domains of genome-wide gene expression dysregulation in Down's syndrome
    • Letourneau A, Santoni FA, Bonilla X, et al. Domains of genome-wide gene expression dysregulation in Down's syndrome. Nature 2014; 508: 345-350.
    • (2014) Nature , vol.508 , pp. 345-350
    • Letourneau, A.1    Santoni, F.A.2    Bonilla, X.3
  • 72
    • 84901651797 scopus 로고    scopus 로고
    • Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation
    • Lane AA, Chapuy B, Lin CY, et al. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. Nat Genet 2014; 46: 618-623.
    • (2014) Nat Genet , vol.46 , pp. 618-623
    • Lane, A.A.1    Chapuy, B.2    Lin, C.Y.3
  • 73
    • 84884412859 scopus 로고    scopus 로고
    • Usp16 contributes to somatic stemcell defects in Down's syndrome
    • Adorno M, Sikandar S, Mitra SS, et al. Usp16 contributes to somatic stemcell defects in Down's syndrome. Nature 2013; 501: 380-384.
    • (2013) Nature , vol.501 , pp. 380-384
    • Adorno, M.1    Sikandar, S.2    Mitra, S.S.3
  • 75
  • 77
    • 35548986309 scopus 로고    scopus 로고
    • Regulation of cell cycle progression and gene expression by H2A deubiquitination
    • Joo HY, Zhai L, Yang C, et al. Regulation of cell cycle progression and gene expression by H2A deubiquitination. Nature 2007; 449: 1068-1072.
    • (2007) Nature , vol.449 , pp. 1068-1072
    • Joo, H.Y.1    Zhai, L.2    Yang, C.3
  • 78
    • 79957562024 scopus 로고    scopus 로고
    • No paradox, no progress: Inverse cancer comorbidity in people with other complex diseases
    • Tabares-Seisdedos R, Dumont N, Baudot A, et al. No paradox, no progress: inverse cancer comorbidity in people with other complex diseases. Lancet Oncol 2011; 12: 604-608.
    • (2011) Lancet Oncol , vol.12 , pp. 604-608
    • Tabares-Seisdedos, R.1    Dumont, N.2    Baudot, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.