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Volumn 162, Issue 1, 2015, Pages 188-199

Wnt5a signaling increases IL-12 secretion by human dendritic cells and enhances IFN-γ production by CD4+ T cells

Author keywords

DCs; IFN ; IL 10; IL 12; T cell; Wnt

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; FRIZZLED PROTEIN; GAMMA INTERFERON; INTERLEUKIN 12; LIGAND; WNT5A PROTEIN; CYTOKINE; ONCOPROTEIN; TOLL LIKE RECEPTOR; WNT PROTEIN; WNT11 PROTEIN, HUMAN; WNT4 PROTEIN; WNT5A PROTEIN, HUMAN;

EID: 84908440134     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2014.08.015     Document Type: Article
Times cited : (32)

References (71)
  • 1
    • 33745712871 scopus 로고    scopus 로고
    • Dendritic cells in a mature age
    • Reis e Sousa C. Dendritic cells in a mature age. Nat Rev Immunol 2006, 6:476-483.
    • (2006) Nat Rev Immunol , vol.6 , pp. 476-483
    • Reis e Sousa, C.1
  • 2
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • Palucka K., Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012, 12:265-277.
    • (2012) Nat Rev Cancer , vol.12 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 4
    • 79954506102 scopus 로고    scopus 로고
    • Dendritic cell control of tolerogenic responses
    • Manicassamy S., Pulendran B. Dendritic cell control of tolerogenic responses. Immunol Rev 2011, 241:206-227.
    • (2011) Immunol Rev , vol.241 , pp. 206-227
    • Manicassamy, S.1    Pulendran, B.2
  • 5
    • 84874227669 scopus 로고    scopus 로고
    • Regulatory dendritic cells: there is more than just immune activation
    • Schmidt S.V., Nino-Castro A.C., Schultze J.L. Regulatory dendritic cells: there is more than just immune activation. Front Immunol 2012, 3:274.
    • (2012) Front Immunol , vol.3 , pp. 274
    • Schmidt, S.V.1    Nino-Castro, A.C.2    Schultze, J.L.3
  • 6
    • 84866040786 scopus 로고    scopus 로고
    • Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity
    • Mayer C.T., Berod L., Sparwasser T. Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity. Front Immunol 2012, 3:183.
    • (2012) Front Immunol , vol.3 , pp. 183
    • Mayer, C.T.1    Berod, L.2    Sparwasser, T.3
  • 7
    • 70349932747 scopus 로고    scopus 로고
    • Towards an integrated view of Wnt signaling in development
    • van Amerongen R., Nusse R. Towards an integrated view of Wnt signaling in development. Development 2009, 136:3205-3214.
    • (2009) Development , vol.136 , pp. 3205-3214
    • van Amerongen, R.1    Nusse, R.2
  • 9
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers H., Nusse R. Wnt/beta-catenin signaling and disease. Cell 2012, 149:1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 11
    • 41649116120 scopus 로고    scopus 로고
    • Non-conventional Frizzled ligands and Wnt receptors
    • Hendrickx M., Leyns L. Non-conventional Frizzled ligands and Wnt receptors. Dev Growth Differ 2008, 50:229-243.
    • (2008) Dev Growth Differ , vol.50 , pp. 229-243
    • Hendrickx, M.1    Leyns, L.2
  • 12
    • 0034727104 scopus 로고    scopus 로고
    • LDL-receptor-related proteins in Wnt signal transduction
    • Tamai K., Semenov M., Kato Y., Spokony R., Liu C., Katsuyama Y., et al. LDL-receptor-related proteins in Wnt signal transduction. Nature 2000, 407:530-535.
    • (2000) Nature , vol.407 , pp. 530-535
    • Tamai, K.1    Semenov, M.2    Kato, Y.3    Spokony, R.4    Liu, C.5    Katsuyama, Y.6
  • 13
    • 45849117967 scopus 로고    scopus 로고
    • Wnt signal transduction pathways
    • Komiya Y., Habas R. Wnt signal transduction pathways. Organogenesis 2008, 4:68-75.
    • (2008) Organogenesis , vol.4 , pp. 68-75
    • Komiya, Y.1    Habas, R.2
  • 15
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S., Moon R.T. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 2009, 10:468-477.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 16
    • 80054730000 scopus 로고    scopus 로고
    • Wnt5a skews dendritic cell differentiation to an unconventional phenotype with tolerogenic features
    • Valencia J., Hernandez-Lopez C., Martinez V.G., Hidalgo L., Zapata A.G., Vicente A., et al. Wnt5a skews dendritic cell differentiation to an unconventional phenotype with tolerogenic features. J Immunol 2011, 187:4129-4139.
    • (2011) J Immunol , vol.187 , pp. 4129-4139
    • Valencia, J.1    Hernandez-Lopez, C.2    Martinez, V.G.3    Hidalgo, L.4    Zapata, A.G.5    Vicente, A.6
  • 17
    • 84862066130 scopus 로고    scopus 로고
    • Wnt5a induces a tolerogenic phenotype of macrophages in sepsis and breast cancer patients
    • Bergenfelz C., Medrek C., Ekstrom E., Jirstrom K., Janols H., Wullt M., et al. Wnt5a induces a tolerogenic phenotype of macrophages in sepsis and breast cancer patients. J Immunol 2012, 188:5448-5458.
    • (2012) J Immunol , vol.188 , pp. 5448-5458
    • Bergenfelz, C.1    Medrek, C.2    Ekstrom, E.3    Jirstrom, K.4    Janols, H.5    Wullt, M.6
  • 18
    • 33746660207 scopus 로고    scopus 로고
    • The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation
    • Blumenthal A., Ehlers S., Lauber J., Buer J., Lange C., Goldmann T., et al. The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood 2006, 108:965-973.
    • (2006) Blood , vol.108 , pp. 965-973
    • Blumenthal, A.1    Ehlers, S.2    Lauber, J.3    Buer, J.4    Lange, C.5    Goldmann, T.6
  • 21
    • 77955480360 scopus 로고    scopus 로고
    • Wnt5a induces endothelial inflammation via beta-catenin-independent signaling
    • Kim J., Kim J., Kim D.W., Ha Y., Ihm M.H., Kim H., et al. Wnt5a induces endothelial inflammation via beta-catenin-independent signaling. J Immunol 2010, 185:1274-1282.
    • (2010) J Immunol , vol.185 , pp. 1274-1282
    • Kim, J.1    Kim, J.2    Kim, D.W.3    Ha, Y.4    Ihm, M.H.5    Kim, H.6
  • 22
    • 84857270110 scopus 로고    scopus 로고
    • WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production
    • Rauner M., Stein N., Winzer M., Goettsch C., Zwerina J., Schett G., et al. WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production. J Bone Miner Res 2012, 27:575-585.
    • (2012) J Bone Miner Res , vol.27 , pp. 575-585
    • Rauner, M.1    Stein, N.2    Winzer, M.3    Goettsch, C.4    Zwerina, J.5    Schett, G.6
  • 23
    • 40749112792 scopus 로고    scopus 로고
    • Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10
    • Pereira C., Schaer D.J., Bachli E.B., Kurrer M.O., Schoedon G. Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10. Arterioscler Thromb Vasc Biol 2008, 28:504-510.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 504-510
    • Pereira, C.1    Schaer, D.J.2    Bachli, E.B.3    Kurrer, M.O.4    Schoedon, G.5
  • 24
    • 33751295132 scopus 로고    scopus 로고
    • Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion
    • Kurayoshi M., Oue N., Yamamoto H., Kishida M., Inoue A., Asahara T., et al. Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res 2006, 66:10439-10448.
    • (2006) Cancer Res , vol.66 , pp. 10439-10448
    • Kurayoshi, M.1    Oue, N.2    Yamamoto, H.3    Kishida, M.4    Inoue, A.5    Asahara, T.6
  • 25
    • 33644833865 scopus 로고    scopus 로고
    • Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor - an expression in non-small-cell lung cancer
    • Huang C.L., Liu D., Nakano J., Ishikawa S., Kontani K., Yokomise H., et al. Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor - an expression in non-small-cell lung cancer. J Clin Oncol 2005, 23:8765-8773.
    • (2005) J Clin Oncol , vol.23 , pp. 8765-8773
    • Huang, C.L.1    Liu, D.2    Nakano, J.3    Ishikawa, S.4    Kontani, K.5    Yokomise, H.6
  • 26
    • 33645774667 scopus 로고    scopus 로고
    • Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
    • Pukrop T., Klemm F., Hagemann T., Gradl D., Schulz M., Siemes S., et al. Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines. Proc Natl Acad Sci U S A 2006, 103:5454-5459.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 5454-5459
    • Pukrop, T.1    Klemm, F.2    Hagemann, T.3    Gradl, D.4    Schulz, M.5    Siemes, S.6
  • 27
    • 84879114342 scopus 로고    scopus 로고
    • Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance
    • Oderup C., LaJevic M., Butcher E.C. Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance. J Immunol 2013, 190:6126-6134.
    • (2013) J Immunol , vol.190 , pp. 6126-6134
    • Oderup, C.1    LaJevic, M.2    Butcher, E.C.3
  • 28
    • 81155139119 scopus 로고    scopus 로고
    • Adipose tissue macrophages inhibit adipogenesis of mesenchymal precursor cells via wnt-5a in humans
    • Bilkovski R., Schulte D.M., Oberhauser F., Mauer J., Hampel B., Gutschow C., et al. Adipose tissue macrophages inhibit adipogenesis of mesenchymal precursor cells via wnt-5a in humans. Int J Obes (Lond) 2011, 35:1450-1454.
    • (2011) Int J Obes (Lond) , vol.35 , pp. 1450-1454
    • Bilkovski, R.1    Schulte, D.M.2    Oberhauser, F.3    Mauer, J.4    Hampel, B.5    Gutschow, C.6
  • 30
    • 77950345694 scopus 로고    scopus 로고
    • Transient beta-catenin stabilization modifies lineage output from human thymic CD34+CD1a-progenitors
    • Valencia J., Hernandez-Lopez C., Martinez V.G., Hidalgo L., Zapata A.G., Vicente A., et al. Transient beta-catenin stabilization modifies lineage output from human thymic CD34+CD1a-progenitors. J Leukoc Biol 2010, 87:405-414.
    • (2010) J Leukoc Biol , vol.87 , pp. 405-414
    • Valencia, J.1    Hernandez-Lopez, C.2    Martinez, V.G.3    Hidalgo, L.4    Zapata, A.G.5    Vicente, A.6
  • 32
    • 84867338596 scopus 로고    scopus 로고
    • The Wingless homolog Wnt5a stimulates phagocytosis but not bacterial killing
    • Maiti G., Naskar D., Sen M. The Wingless homolog Wnt5a stimulates phagocytosis but not bacterial killing. Proc Natl Acad Sci U S A 2012, 109:16600-16605.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 16600-16605
    • Maiti, G.1    Naskar, D.2    Sen, M.3
  • 33
    • 34548448100 scopus 로고    scopus 로고
    • Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells
    • Lehtonen A., Ahlfors H., Veckman V., Miettinen M., Lahesmaa R., Julkunen I. Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J Leukoc Biol 2007, 82:710-720.
    • (2007) J Leukoc Biol , vol.82 , pp. 710-720
    • Lehtonen, A.1    Ahlfors, H.2    Veckman, V.3    Miettinen, M.4    Lahesmaa, R.5    Julkunen, I.6
  • 34
    • 0344441412 scopus 로고    scopus 로고
    • Wnt-1 signaling inhibits human umbilical vein endothelial cell proliferation and alters cell morphology
    • Cheng C.W., Smith S.K., Charnock-Jones D.S. Wnt-1 signaling inhibits human umbilical vein endothelial cell proliferation and alters cell morphology. Exp Cell Res 2003, 291:415-425.
    • (2003) Exp Cell Res , vol.291 , pp. 415-425
    • Cheng, C.W.1    Smith, S.K.2    Charnock-Jones, D.S.3
  • 35
    • 33847268280 scopus 로고    scopus 로고
    • Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration
    • Wu B., Crampton S.P., Hughes C.C. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 2007, 26:227-239.
    • (2007) Immunity , vol.26 , pp. 227-239
    • Wu, B.1    Crampton, S.P.2    Hughes, C.C.3
  • 36
    • 80054697178 scopus 로고    scopus 로고
    • Pathogen-specific TLR2 protein activation programs macrophages to induce Wnt-beta-catenin signaling
    • Bansal K., Trinath J., Chakravortty D., Patil S.A., Balaji K.N. Pathogen-specific TLR2 protein activation programs macrophages to induce Wnt-beta-catenin signaling. J Biol Chem 2011, 286:37032-37044.
    • (2011) J Biol Chem , vol.286 , pp. 37032-37044
    • Bansal, K.1    Trinath, J.2    Chakravortty, D.3    Patil, S.A.4    Balaji, K.N.5
  • 37
    • 79955479506 scopus 로고    scopus 로고
    • Wnt signaling in macrophages: augmenting and inhibiting mycobacteria-induced inflammatory responses
    • Schaale K., Neumann J., Schneider D., Ehlers S., Reiling N. Wnt signaling in macrophages: augmenting and inhibiting mycobacteria-induced inflammatory responses. Eur J Cell Biol 2011, 90:553-559.
    • (2011) Eur J Cell Biol , vol.90 , pp. 553-559
    • Schaale, K.1    Neumann, J.2    Schneider, D.3    Ehlers, S.4    Reiling, N.5
  • 38
    • 33744976112 scopus 로고    scopus 로고
    • The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum
    • Keeble T.R., Halford M.M., Seaman C., Kee N., Macheda M., Anderson R.B., et al. The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum. J Neurosci 2006, 26:5840-5848.
    • (2006) J Neurosci , vol.26 , pp. 5840-5848
    • Keeble, T.R.1    Halford, M.M.2    Seaman, C.3    Kee, N.4    Macheda, M.5    Anderson, R.B.6
  • 39
    • 5344273899 scopus 로고    scopus 로고
    • Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
    • Lu W., Yamamoto V., Ortega B., Baltimore D. Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell 2004, 119:97-108.
    • (2004) Cell , vol.119 , pp. 97-108
    • Lu, W.1    Yamamoto, V.2    Ortega, B.3    Baltimore, D.4
  • 40
    • 48249092251 scopus 로고    scopus 로고
    • Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system
    • Wouda R.R., Bansraj M.R., de Jong A.W., Noordermeer J.N., Fradkin L.G. Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system. Development 2008, 135:2277-2287.
    • (2008) Development , vol.135 , pp. 2277-2287
    • Wouda, R.R.1    Bansraj, M.R.2    de Jong, A.W.3    Noordermeer, J.N.4    Fradkin, L.G.5
  • 41
    • 75749128649 scopus 로고    scopus 로고
    • Ryks: new partners for Wnts in the developing and regenerating nervous system
    • Fradkin L.G., Dura J.M., Noordermeer J.N. Ryks: new partners for Wnts in the developing and regenerating nervous system. Trends Neurosci 2010, 33:84-92.
    • (2010) Trends Neurosci , vol.33 , pp. 84-92
    • Fradkin, L.G.1    Dura, J.M.2    Noordermeer, J.N.3
  • 42
    • 55349114398 scopus 로고    scopus 로고
    • Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis
    • Lyu J., Yamamoto V., Lu W. Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis. Dev Cell 2008, 15:773-780.
    • (2008) Dev Cell , vol.15 , pp. 773-780
    • Lyu, J.1    Yamamoto, V.2    Lu, W.3
  • 43
    • 84891786037 scopus 로고    scopus 로고
    • Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor
    • Povinelli B.J., Nemeth M.J. Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor. Stem Cells 2014, 32:105-115.
    • (2014) Stem Cells , vol.32 , pp. 105-115
    • Povinelli, B.J.1    Nemeth, M.J.2
  • 45
    • 34447326176 scopus 로고    scopus 로고
    • WNT5A - target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer
    • Ripka S., Konig A., Buchholz M., Wagner M., Sipos B., Kloppel G., et al. WNT5A - target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer. Carcinogenesis 2007, 28:1178-1187.
    • (2007) Carcinogenesis , vol.28 , pp. 1178-1187
    • Ripka, S.1    Konig, A.2    Buchholz, M.3    Wagner, M.4    Sipos, B.5    Kloppel, G.6
  • 46
    • 65449136296 scopus 로고    scopus 로고
    • Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon
    • Romanowska M., Evans A., Kellock D., Bray S.E., McLean K., Donandt S., et al. Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon. PLoS ONE 2009, 4:e5354.
    • (2009) PLoS ONE , vol.4 , pp. e5354
    • Romanowska, M.1    Evans, A.2    Kellock, D.3    Bray, S.E.4    McLean, K.5    Donandt, S.6
  • 48
    • 77954844177 scopus 로고    scopus 로고
    • Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity
    • Ouchi N., Higuchi A., Ohashi K., Oshima Y., Gokce N., Shibata R., et al. Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science 2010, 329:454-457.
    • (2010) Science , vol.329 , pp. 454-457
    • Ouchi, N.1    Higuchi, A.2    Ohashi, K.3    Oshima, Y.4    Gokce, N.5    Shibata, R.6
  • 49
    • 84857545934 scopus 로고    scopus 로고
    • Pro-inflammatory wnt5a and anti-inflammatory sFRP5 are differentially regulated by nutritional factors in obese human subjects
    • Schulte D.M., Muller N., Neumann K., Oberhauser F., Faust M., Gudelhofer H., et al. Pro-inflammatory wnt5a and anti-inflammatory sFRP5 are differentially regulated by nutritional factors in obese human subjects. PLoS ONE 2012, 7:e32437.
    • (2012) PLoS ONE , vol.7 , pp. e32437
    • Schulte, D.M.1    Muller, N.2    Neumann, K.3    Oberhauser, F.4    Faust, M.5    Gudelhofer, H.6
  • 50
    • 84886280379 scopus 로고    scopus 로고
    • Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
    • Shan M., Gentile M., Yeiser J.R., Walland A.C., Bornstein V.U., Chen K., et al. Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. Science 2013, 342:447-453.
    • (2013) Science , vol.342 , pp. 447-453
    • Shan, M.1    Gentile, M.2    Yeiser, J.R.3    Walland, A.C.4    Bornstein, V.U.5    Chen, K.6
  • 51
    • 0036781671 scopus 로고    scopus 로고
    • Hung MC. beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer
    • Deng J., Miller S.A., Wang H.Y., Xia W., Wen Y., Zhou B.P., et al. Hung MC. beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell 2002, 2:323-334.
    • (2002) Cancer Cell , vol.2 , pp. 323-334
    • Deng, J.1    Miller, S.A.2    Wang, H.Y.3    Xia, W.4    Wen, Y.5    Zhou, B.P.6
  • 52
    • 65949106610 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells
    • Du Q., Zhang X., Cardinal J., Cao Z., Guo Z., Shao L., et al. Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells. Cancer Res 2009, 69:3764-3771.
    • (2009) Cancer Res , vol.69 , pp. 3764-3771
    • Du, Q.1    Zhang, X.2    Cardinal, J.3    Cao, Z.4    Guo, Z.5    Shao, L.6
  • 53
    • 79953200164 scopus 로고    scopus 로고
    • Inhibition of proinflammatory RANTES expression by TGF-beta1 is mediated by glycogen synthase kinase-3beta-dependent beta-catenin signaling
    • Dai C., Wen X., He W., Liu Y. Inhibition of proinflammatory RANTES expression by TGF-beta1 is mediated by glycogen synthase kinase-3beta-dependent beta-catenin signaling. J Biol Chem 2011, 286:7052-7059.
    • (2011) J Biol Chem , vol.286 , pp. 7052-7059
    • Dai, C.1    Wen, X.2    He, W.3    Liu, Y.4
  • 54
    • 84860822029 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 beta inhibitor suppresses Porphyromonas gingivalis lipopolysaccharide-induced CD40 expression by inhibiting nuclear factor-kappa B activation in mouse osteoblasts
    • Die L., Yan P., Jun Jiang Z., Min Hua T., Cai W., Xing L. Glycogen synthase kinase-3 beta inhibitor suppresses Porphyromonas gingivalis lipopolysaccharide-induced CD40 expression by inhibiting nuclear factor-kappa B activation in mouse osteoblasts. Mol Immunol 2012, 52:38-49.
    • (2012) Mol Immunol , vol.52 , pp. 38-49
    • Die, L.1    Yan, P.2    Jun Jiang, Z.3    Min Hua, T.4    Cai, W.5    Xing, L.6
  • 55
    • 35348968837 scopus 로고    scopus 로고
    • Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation
    • Jiang A., Bloom O., Ono S., Cui W., Unternaehrer J., Jiang S., et al. Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity 2007, 27:610-624.
    • (2007) Immunity , vol.27 , pp. 610-624
    • Jiang, A.1    Bloom, O.2    Ono, S.3    Cui, W.4    Unternaehrer, J.5    Jiang, S.6
  • 56
    • 73149097234 scopus 로고    scopus 로고
    • Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)
    • Beurel E., Michalek S.M., Jope R.S. Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). Trends Immunol 2010, 31:24-31.
    • (2010) Trends Immunol , vol.31 , pp. 24-31
    • Beurel, E.1    Michalek, S.M.2    Jope, R.S.3
  • 57
    • 33846921242 scopus 로고    scopus 로고
    • GSK-3 mediates differentiation and activation of proinflammatory dendritic cells
    • Rodionova E., Conzelmann M., Maraskovsky E., Hess M., Kirsch M., Giese T., et al. GSK-3 mediates differentiation and activation of proinflammatory dendritic cells. Blood 2007, 109:1584-1592.
    • (2007) Blood , vol.109 , pp. 1584-1592
    • Rodionova, E.1    Conzelmann, M.2    Maraskovsky, E.3    Hess, M.4    Kirsch, M.5    Giese, T.6
  • 58
    • 34548597045 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 activity during development of bone marrow-derived dendritic cells (DCs) essential for the DC function to induce T helper 2 polarization
    • Ono T., Yanagawa Y., Iwabuchi K., Nonomura K., Onoe K. Glycogen synthase kinase 3 activity during development of bone marrow-derived dendritic cells (DCs) essential for the DC function to induce T helper 2 polarization. Immunology 2007, 122:189-198.
    • (2007) Immunology , vol.122 , pp. 189-198
    • Ono, T.1    Yanagawa, Y.2    Iwabuchi, K.3    Nonomura, K.4    Onoe, K.5
  • 59
    • 77955634800 scopus 로고    scopus 로고
    • Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine
    • Manicassamy S., Reizis B., Ravindran R., Nakaya H., Salazar-Gonzalez R.M., Wang Y.C., et al. Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine. Science 2010, 329:849-853.
    • (2010) Science , vol.329 , pp. 849-853
    • Manicassamy, S.1    Reizis, B.2    Ravindran, R.3    Nakaya, H.4    Salazar-Gonzalez, R.M.5    Wang, Y.C.6
  • 60
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Mikels A.J., Nusse R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 2006, 4:e115.
    • (2006) PLoS Biol , vol.4 , pp. e115
    • Mikels, A.J.1    Nusse, R.2
  • 61
    • 84862888212 scopus 로고    scopus 로고
    • Wnt5a inhibits the CpG oligodeoxynucleotide-triggered activation of human plasmacytoid dendritic cells
    • Hack K., Reilly L., Proby C., Fleming C., Leigh I., Foerster J. Wnt5a inhibits the CpG oligodeoxynucleotide-triggered activation of human plasmacytoid dendritic cells. Clin Exp Dermatol 2012, 37:557-561.
    • (2012) Clin Exp Dermatol , vol.37 , pp. 557-561
    • Hack, K.1    Reilly, L.2    Proby, C.3    Fleming, C.4    Leigh, I.5    Foerster, J.6
  • 63
    • 0345356929 scopus 로고    scopus 로고
    • Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
    • Liang H., Chen Q., Coles A.H., Anderson S.J., Pihan G., Bradley A., et al. Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue. Cancer Cell 2003, 4:349-360.
    • (2003) Cancer Cell , vol.4 , pp. 349-360
    • Liang, H.1    Chen, Q.2    Coles, A.H.3    Anderson, S.J.4    Pihan, G.5    Bradley, A.6
  • 64
    • 37049021394 scopus 로고    scopus 로고
    • WNT5A is epigenetically silenced in hematologic malignancies and inhibits leukemia cell growth as a tumor suppressor
    • Ying J., Li H., Chen Y.W., Srivastava G., Gao Z., Tao Q. WNT5A is epigenetically silenced in hematologic malignancies and inhibits leukemia cell growth as a tumor suppressor. Blood 2007, 110:4130-4132.
    • (2007) Blood , vol.110 , pp. 4130-4132
    • Ying, J.1    Li, H.2    Chen, Y.W.3    Srivastava, G.4    Gao, Z.5    Tao, Q.6
  • 65
    • 84867211734 scopus 로고    scopus 로고
    • The Wnt inhibitor secreted Frizzled-Related Protein 1 (sFRP1) promotes human Th17 differentiation
    • Lee Y.S., Lee K.A., Yoon H.B., Yoo S.A., Park Y.W., Chung Y., et al. The Wnt inhibitor secreted Frizzled-Related Protein 1 (sFRP1) promotes human Th17 differentiation. Eur J Immunol 2012, 42:2564-2573.
    • (2012) Eur J Immunol , vol.42 , pp. 2564-2573
    • Lee, Y.S.1    Lee, K.A.2    Yoon, H.B.3    Yoo, S.A.4    Park, Y.W.5    Chung, Y.6
  • 66
    • 69049088648 scopus 로고    scopus 로고
    • T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma
    • Yu Q., Sharma A., Oh S.Y., Moon H.G., Hossain M.Z., Salay T.M., et al. T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma. Nat Immunol 2009, 10:992-999.
    • (2009) Nat Immunol , vol.10 , pp. 992-999
    • Yu, Q.1    Sharma, A.2    Oh, S.Y.3    Moon, H.G.4    Hossain, M.Z.5    Salay, T.M.6
  • 67
    • 75749152053 scopus 로고    scopus 로고
    • Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner
    • Notani D., Gottimukkala K.P., Jayani R.S., Limaye A.S., Damle M.V., Mehta S., et al. Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner. PLoS Biol 2010, 8:e1000296.
    • (2010) PLoS Biol , vol.8 , pp. e1000296
    • Notani, D.1    Gottimukkala, K.P.2    Jayani, R.S.3    Limaye, A.S.4    Damle, M.V.5    Mehta, S.6
  • 68
    • 84856460891 scopus 로고    scopus 로고
    • Regulation of mature T cell responses by the Wnt signaling pathway
    • Xue H.H., Zhao D.M. Regulation of mature T cell responses by the Wnt signaling pathway. Ann N Y Acad Sci 2012, 1247:16-33.
    • (2012) Ann N Y Acad Sci , vol.1247 , pp. 16-33
    • Xue, H.H.1    Zhao, D.M.2
  • 69
    • 67650465237 scopus 로고    scopus 로고
    • Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
    • Gattinoni L., Zhong X.S., Palmer D.C., Ji Y., Hinrichs C.S., Yu Z., et al. Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells. Nat Med 2009, 15:808-813.
    • (2009) Nat Med , vol.15 , pp. 808-813
    • Gattinoni, L.1    Zhong, X.S.2    Palmer, D.C.3    Ji, Y.4    Hinrichs, C.S.5    Yu, Z.6
  • 70
    • 79251545810 scopus 로고    scopus 로고
    • Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-gamma1 phosphorylation
    • Driessens G., Zheng Y., Locke F., Cannon J.L., Gounari F., Gajewski T.F. Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-gamma1 phosphorylation. J Immunol 2011, 186:784-790.
    • (2011) J Immunol , vol.186 , pp. 784-790
    • Driessens, G.1    Zheng, Y.2    Locke, F.3    Cannon, J.L.4    Gounari, F.5    Gajewski, T.F.6


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