Mice lacking the circadian modulators SHARP1 and SHARP2 display altered sleep and mixed state endophenotypes of psychiatric disorders

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Baier, Paul C ^a,b   Brzózka, Magdalena M ^c   Shahmoradi, Ali ^d   Reinecke, Lisa ^d   Kroos, Christina ^d   Wichert, Sven P ^c   Oster, Henrik ^e,f   Wehr, Michael C ^c   Taneja, Reshma ^g   Hirrlinger, Johannes ^d,h   Rossner, Moritz J ^c,d  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^e MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^f UNIVERSITY OF LÜBECK   (Germany)

^g NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^h UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; PER1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SHARP1; TRANSCRIPTION FACTOR SHARP2; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BHLHB3 PROTEIN, MOUSE; HEY2 PROTEIN, MOUSE; REPRESSOR PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ENDOPHENOTYPE; EXPLORATORY BEHAVIOR; GENE; GENE EXPRESSION; HYPERACTIVITY; LIGHT DARK CYCLE; MALE; MEMORY DISORDER; MENTAL DISEASE; MOLECULAR CLOCK; MOUSE; NONHUMAN; PER1 GENE; PREPULSE INHIBITION; SENSORY GATING; SHARP1 GENE; SLEEP DISORDER; SLEEP TIME; THETA RHYTHM; VOLUNTARY MOVEMENT; WORKING MEMORY; ANIMAL; C57BL MOUSE; CIRCADIAN RHYTHM; COMPLICATION; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SLEEP; WAKEFULNESS;

MUS;

ANIMALS; ANXIETY; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CLOZAPINE; ENDOPHENOTYPES; EXPLORATORY BEHAVIOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; MALE; MENTAL DISORDERS; MICE, INBRED C57BL; PREPULSE INHIBITION; REPRESSOR PROTEINS; SLEEP; TRANSCRIPTION FACTORS; WAKEFULNESS;

EID: 84908439923     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110310     Document Type: Article

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