Calcium in the heart: From physiology to disease

Experimental Physiology

Volumn 99, Issue 10, 2014, Pages 1273-1282

  Eisner, David ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE;

ADRENERGIC STIMULATION; AMPLITUDE MODULATION; ARRHYTHMOGENESIS; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; EFFUSION; EXCITATION CONTRACTION COUPLING; EXERCISE; FEEDBACK SYSTEM; HEART; HEART ARRHYTHMIA; HEART DISEASE; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HUMAN; MEMBRANE; MUSCLE CELL; NEGATIVE FEEDBACK; PHYSIOLOGY; SARCOPLASMIC RETICULUM; SODIUM CALCIUM EXCHANGE; STEADY STATE; SURFACE PROPERTY; ANIMAL; CARDIAC MUSCLE; HEART CONTRACTION; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM SIGNALING; HEART; HEART DISEASES; HUMANS; MYOCARDIAL CONTRACTION; MYOCARDIUM; SARCOPLASMIC RETICULUM;

EID: 84908387174     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2013.077305     Document Type: Article

References (64)

1. 2+ channels and ryanodine receptors in rat ventricular myocytes. J Gen Physiol 108, 435-454.
2. Adams WA, Trafford AW & Eisner DA (1998). 2, 3-Butanedione monoxime (BDM) decreases sarcoplasmic reticulum Ca content by stimulating Ca release in isolated rat ventricular myocytes. Pflugers Arch 436, 776-781.
3. Allen DG & Blinks JR (1978). Calcium transients in aequorin-injected frog cardiac muscle. Nature 273, 509-513.
4. Allen DG & Kurihara S (1980). Calcium transients in mammalian ventricular muscle. Eur Heart J Suppl A, 5-15.
5. 2+ content in cardiac myocytes. Am J Physiol Cell Physiol 268, C1313-C1329.
6. i waves in cardiac myocytes. Am J Physiol Cell Physiol 270, C148-C159.
7. Cheng H, Lederer WJ & Cannell MB (1993). Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262, 740-744.
8. 2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes. J Physiol 529, 661-668.
9. Crossman DJ, Ruygrok PR, Soeller C & Cannell MB (2011). Changes in the organization of excitation-contraction coupling structures in failing human heart. PLoS One 6, e17901.
10. 2+ in cardiac hypertrophy. Cardiovasc Res 62, 538-547.
11. Díaz ME, Trafford AW & Eisner DA (2001). The role of intracellular Ca buffers in determining the shape of the systolic Ca transient in cardiac ventricular myocytes. Pflugers Arch 442, 96-100.
12. 2+ release. J Physiol 501, 3-16.
13. Dibb KM, Clarke JD, Horn MA, Richards MA, Graham HK, Eisner DA & Trafford AW (2009). Characterization of an extensive transverse tubular network in sheep atrial myocytes and its depletion in heart failure. Circ Heart Fail 2, 482-489.
14. 2+ wave generation. J Physiol 590, 6093-6108.
15. Eisner D, Bode E, Venetucci L & Trafford A (2013a). Calcium flux balance in the heart. J Mol Cell Cardiol 58, 110-117.
16. Eisner D, Caldwell J & Trafford A (2013b). Sarcoplasmic reticulum Ca-ATPase and heart failure 20 years later. Circ Res 113, 958-961.
17. Eisner DA, Choi HS, Díaz ME, O'Neill SC & Trafford AW (2000). Integrative analysis of calcium cycling in cardiac muscle. Circ Res 87, 1087-1094.
18. Eisner DA, Kashimura T, O'Neill SC, Venetucci LA & Trafford AW (2009). What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis? J Mol Cell Cardiol 46, 474-481.
19. Eisner DA & Valdeolmillos M (1986). A study of intracellular calcium oscillations in sheep cardiac Purkinje fibres measured at the single cell level. J Physiol 372, 539-556.
20. Eschenhagen T (2010). Is ryanodine receptor phosphorylation key to the fight or flight response and heart failure? J Clin Invest 120, 4197-4203.
21. Fabiato A (1985). Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol 85, 247-289.
22. Ferrier GR, Saunders JH & Mendez C (1973). A cellular mechanism for the generation of ventricular arrhythmias by acetylstrophanthidin. Circ Res 32, 600-609.
23. 2+ channels in canine tachycardia-induced heart failure. Cardiovasc Res 49, 298-307.
24. 2+ release in myocytes from chronically ischemic myocardium. Circ Res 102, 338-346.
25. 2+ spark. J Mol Cell Cardiol 48, 293-301.
26. Hobai IA & O'Rourke B (2001). Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation 103, 1577-1584.
27. Houser SR (2001). Reduced abundance of transverse tubules and L-type calcium channels: another cause of defective contractility in failing ventricular myocytes. Cardiovasc Res 49, 253-256.
28. Houser SR, Piacentino V III & Weisser J (2000). Abnormalities of calcium cycling in the hypertrophied and failing heart. J Mol Cell Cardiol 32, 1595-1607.
29. Iino S, Cui Y, Galione A & Terrar DA (1997). Actions of cADP-ribose and its antagonists on contraction in guinea pig isolated ventricular myocytes: influence of temperature. Circ Res 81, 879-884.
30. 2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death. Circ Res 91, 218-225.
31. R4496C mouse model of CPVT, β-adrenergic stimulation induces Ca waves by increasing SR Ca content and not by decreasing the threshold for Ca waves. Circ Res 107, 1483-1489.
32. Laitinen PJ, Brown KM, Piippo K, Swan H, Devaney JM, Brahmbhatt B, Donarum EA, Marino M, Tiso N, Viitasalo M, Toivonen L, Stephan DA & Kontula K (2001). Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation 103, 485-490.
33. Lederer WJ & Tsien RW (1976). Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres. J Physiol 263, 73-100.
34. MacDonnell SM, García-Rivas G, Scherman JA, Kubo H, Chen X, Valdivia H & Houser SR (2008). Adrenergic regulation of cardiac contractility does not involve phosphorylation of the cardiac ryanodine receptor at serine 2808. Circ Res 102, e65-e72.
35. 2+ release and storage in cardiac myocytes isolated from guinea-pig and rat ventricle. Cell Calcium 41, 537-546.
36. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N & Marks AR (2000). PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101, 365-376.
37. Mechmann S & Pott L (1986). Identification of Na-Ca exchange current in single cardiac myocytes. Nature 319, 597-599.
38. 2+ release channels and their regulation by endogenous effectors. Ann Rev Physiol 56, 485-508.
39. 2+ release during diastole and systole in isolated rat ventricular myocytes. J Physiol 430, 519-536.
40. 2+ release and sarcoplasmic reticulum calcium content in rat ventricular myocytes. J Physiol 502, 471-479.
41. 2+ content and membrane current in isolated rat ventricular myocytes. J Physiol 507, 759-769.
42. Parekh AB & Putney JW Jr (2005). Store-operated calcium channels. Physiol Rev 85, 757-810.
43. Piacentino V III, Weber CR, Chen X, Weisser-Thomas J, Margulies KB, Bers DM & Houser SR (2003). Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ Res 92, 651-658.
44. Pogwizd SM, Schlotthauer K, Li L, Yuan W & Bers DM (2001). Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual β-adrenergic responsiveness. Circ Res 88, 1159-1167.
45. Priori SG, Napolitano C, Tiso N, Memmi M, Vignati G, Bloise R, Sorrentino V & Danieli GA (2001). Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia. Circulation 103, 196-200.
46. Ringer S (1882). Concerning the influence exerted by each of the constituents of the blood on the contraction of the ventricle. J Physiol 3, 380-393.
47. Ringer S (1883). A further contribution regarding the influence of the different constituents of the blood on the contraction of the heart. J Physiol 4, 29-42.
48. Rosen MR, Gelband H & Hoffman BF (1973). Correlation between effects of ouabain on the canine electrocardiogram and transmembrane potentials of isolated Purkinje fibers. Circulation 47, 65-72.
49. Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ & Marks AR (2010). Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. J Clin Invest 120, 4388-4398.
50. 2+ release from sarcoplasmic reticulum in guinea pig ventricular myocytes. Circ Res 76, 102-109.
51. 2+. J Memb Biol 159, 179-185.
52. Tada M & Katz AM (1982). Phosphorylation of the sarcoplasmic reticulum and sarcolemma. Ann Rev Physiol 44, 401-423.
53. Tinker A & Williams AJ (1993). Charged local anesthetics block ionic conduction in the sheep cardiac sarcoplasmic reticulum calcium release channel. Biophys J 65, 852-864.
54. Trafford AW, Díaz ME & Eisner DA (1998). Stimulation of Ca-induced Ca release only transiently increases the systolic Ca transient: measurements of Ca fluxes and sarcoplasmic reticulum Ca. Cardiovasc Res 37, 710-717.
55. 2+ content following depletion. Circ Res 81, 477-484.
56. 2+ fluxes in rat ventricular myocytes. J Physiol 522, 259-270.
57. Trafford AW, Lipp P, O'Neill SC, Niggli E & Eisner DA (1995). Propagating calcium waves initiated by local caffeine application in rat ventricular myocytes. J Physiol 489, 319-326.
58. Trafford AW, O'Neill SC & Eisner DA (1993). Factors affecting the propagation of locally activated systolic Ca transients in rat ventricular myocytes. Pflügers Archiv 425, 181-183.
59. 2+ transient amplitude in adult ventricular myocytes. Circ Res 98, 1299-1305.
60. 2+ content is required. Circ Res 100, 105-111.
61. Venetucci LA, Trafford AW, O'Neill SC & Eisner DA (2008). The sarcoplasmic reticulum and arrhythmogenic calcium release. Cardiovasc Res 77, 285-292.
62. Watanabe H, Chopra N, Laver D, Hwang HS, Davies SS, Roach DE, Duff HJ, Roden DM, Wilde AAM & Knollmann BC (2009). Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans. Nat Med 15, 380-383.
63. Wehrens XHT, Lehnart SE, Huang F, Vest JA, Reiken SR, Mohler PJ, Sun J, Guatimosim S, Song LS, Rosemblit N, D'Armiento JM, Napolitano C, Memmi M, Priori SG, Lederer WJ & Marks AR (2003). FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell 113, 829-840.
64. i in single heart cells revealed by fura-2. Science 235, 325-328.