Differences between magnetoencephalographic (MEG) spectral profiles of drugs acting on GABA at synaptic and extrasynaptic sites: A study in healthy volunteers

Neuropharmacology

Volumn 88, Issue , 2015, Pages 155-163

  Nutt, David ^a   Wilson, Sue ^a   Lingford Hughes, Anne ^a   Myers, Jim ^a   Papadopoulos, Andreas ^b   Muthukumaraswamy, Suresh ^c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

GABA; Gaboxadol; Human; Magnetoencephalography; Tiagabine; Zolpidem

Indexed keywords

GABOXADOL; PLACEBO; TIAGABINE; ZOLPIDEM; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ISOXAZOLE DERIVATIVE; NIPECOTIC ACID DERIVATIVE; PYRIDINE DERIVATIVE;

ADULT; ALPHA RHYTHM; ARTICLE; BETA RHYTHM; CONTROLLED STUDY; CROSSOVER PROCEDURE; DELTA RHYTHM; DRUG HALF LIFE; DRUG MECHANISM; EYELID REFLEX; FEMALE; GABAERGIC SYSTEM; GAMMA RHYTHM; HUMAN; HUMAN EXPERIMENT; MAGNETOENCEPHALOGRAPHY; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SEDATION; SINGLE BLIND PROCEDURE; SINGLE DRUG DOSE; SYNAPSE; SYNAPTIC POTENTIAL; YOUNG ADULT; BRAIN; COMPARATIVE STUDY; DRUG EFFECTS; ELECTROENCEPHALOGRAM; METABOLISM; PHYSIOLOGY; REST;

ADULT; BRAIN; BRAIN WAVES; CROSS-OVER STUDIES; FEMALE; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; HUMANS; ISOXAZOLES; MAGNETOENCEPHALOGRAPHY; MALE; NIPECOTIC ACIDS; PYRIDINES; REST; SINGLE-BLIND METHOD; SYNAPSES; YOUNG ADULT;

EID: 84908377253     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.08.017     Document Type: Article

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