Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 307, Issue 9, 2014, Pages G894-G904

  Meng, Fanyin ^b,c   Onori, Paolo ^e   Han, Yuyan ^a,c   DeMorrow, Sharon ^b,c   Venter, Julie ^c   Francis, Heather ^a,b,c   Franchitto, Antonio ^d,e   Ray, Debolina ^c   Kennedy, Lindsey ^a   Greene, John ^b   Renzi, Anastasia ^e   Mancinelli, Romina ^e   Gaudio, Eugenio ^e   Glaser, Shannon ^a,b,c   Alpini, Gianfranco ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^d Eleonora Lorillard Spencer Cenci Foundation   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Biliary epithelium; Cholestasis; Clock genes; Melatonin; Secretin

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ARALKYLAMINE ACETYLTRANSFERASE; BICARBONATE; COLLAGEN; CYCLIC AMP; CYCLINE; CYTOKERATIN 19; FIBRONECTIN; GELATINASE A; MELATONIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; AANAT PROTEIN, RAT; BILE ACID; CIRCADIAN RHYTHM SIGNALING PROTEIN; CRY1 PROTEIN, RAT; CRYPTOCHROME; PER1 PROTEIN, RAT; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT DISEASE; BILIARY HYPERPLASIA; CHOLESTASIS; CONTROLLED STUDY; DARKNESS; GENE EXPRESSION; HORMONE SYNTHESIS; HYPERPLASIA; HYPOTHALAMUS; LIGHT DARK CYCLE; LIVER FIBROSIS; LONG TERM EXPOSURE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PINEAL BODY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; TRANSCRIPTION INITIATION; ANIMAL; BILE DUCT; BIOSYNTHESIS; BLOOD; FIBROSIS; FISCHER 344 RAT; GENETICS; LIVER; METABOLISM; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; ARNTL TRANSCRIPTION FACTORS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; BILE ACIDS AND SALTS; BILE DUCTS; CHOLESTASIS; CLOCK PROTEINS; COLLAGEN; CRYPTOCHROMES; DARKNESS; FIBROSIS; HYPERPLASIA; LIVER; MALE; MELATONIN; PERIOD CIRCADIAN PROTEINS; PINEAL GLAND; RATS; RATS, INBRED F344;

EID: 84908374047     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00288.2014     Document Type: Article

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