메뉴 건너뛰기




Volumn 272, Issue 2 35-2, 1997, Pages

Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation

Author keywords

gene expression; second messenger system; transport biliary epithelia

Indexed keywords

CYCLIC AMP; CYTOKERATIN 19 FRAGMENT; FORSKOLIN; GAMMA GLUTAMYLTRANSFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; SECRETIN;

EID: 0030900791     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.2.g289     Document Type: Article
Times cited : (132)

References (47)
  • 1
    • 0026758703 scopus 로고
    • Distribution of albumin and α-fetoprotein mRNAs in normal, hyperplastic, and preneoplastic rat liver
    • Alpini, G., E. Aragona, M. Dabeva, R. Salvi, D. A. Shafritz, and N. Tavoloni. Distribution of albumin and α-fetoprotein mRNAs in normal, hyperplastic, and preneoplastic rat liver. Am. J. Pathol. 141: 623-632, 1993.
    • (1993) Am. J. Pathol. , vol.141 , pp. 623-632
    • Alpini, G.1    Aragona, E.2    Dabeva, M.3    Salvi, R.4    Shafritz, D.A.5    Tavoloni, N.6
  • 2
    • 0023863239 scopus 로고
    • Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules
    • Alpini, G., R. Lenzi, L. Sarkozi, and N. Tavoloni. Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. J. Clin. Invest. 81: 569-578, 1988.
    • (1988) J. Clin. Invest. , vol.81 , pp. 569-578
    • Alpini, G.1    Lenzi, R.2    Sarkozi, L.3    Tavoloni, N.4
  • 3
    • 0024435974 scopus 로고
    • Isolation of a nonparenchymal liver cell fraction enriched in cells with biliary epithelial phenotypes
    • Alpini, G., R. Lenzi, W.-R. Zhai, M. H. Liu, P. A. Slott, F. Paronetto, and N. Tavoloni. Isolation of a nonparenchymal liver cell fraction enriched in cells with biliary epithelial phenotypes. Gastroenterology 97: 1248-1260, 1989.
    • (1989) Gastroenterology , vol.97 , pp. 1248-1260
    • Alpini, G.1    Lenzi, R.2    Zhai, W.-R.3    Liu, M.H.4    Slott, P.A.5    Paronetto, F.6    Tavoloni, N.7
  • 4
    • 0024363206 scopus 로고
    • Bile secretory function of intrahepatic biliary epithelium in the rat
    • Gastrointest. Liver Physiol. 20
    • Alpini, G., R. Lenzi, W.-R. Zhai, P. A. Slott, M. H. Liu, L. Sarkozi, and N. Tavoloni. Bile secretory function of intrahepatic biliary epithelium in the rat. Am. J. Physiol. 257 (Gastrointest. Liver Physiol. 20): G124-G133, 1989.
    • (1989) Am. J. Physiol. , vol.257
    • Alpini, G.1    Lenzi, R.2    Zhai, W.-R.3    Slott, P.A.4    Liu, M.H.5    Sarkozi, L.6    Tavoloni, N.7
  • 5
    • 0001850203 scopus 로고
    • The biology of the biliary epithelia
    • edited by I. Arias, J. Boyer, N. Fausto, W. Jakoby, D. Schachter and D. A. Shafritz. New York: Raven
    • Alpini, G., J. O. Phillips, and N. F. LaRusso. The biology of the biliary epithelia. In: The Liver: Biology & Pathobiology (3rd ed.), edited by I. Arias, J. Boyer, N. Fausto, W. Jakoby, D. Schachter and D. A. Shafritz. New York: Raven, 1994, p. 623-653.
    • (1994) The Liver: Biology & Pathobiology (3rd Ed.) , pp. 623-653
    • Alpini, G.1    Phillips, J.O.2    LaRusso, N.F.3
  • 7
    • 0027950288 scopus 로고
    • Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation
    • Gastrointest. Liver Physiol. 29
    • Alpini, G., C. D. Ulrich, J. O. Phillips, L. D. Pham, L. J. Miller, and N. F. LaRusso. Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G922-G928, 1994.
    • (1994) Am. J. Physiol. , vol.266
    • Alpini, G.1    Ulrich, C.D.2    Phillips, J.O.3    Pham, L.D.4    Miller, L.J.5    LaRusso, N.F.6
  • 8
    • 0027661137 scopus 로고
    • Effect of secretin on intracellular pH regulation in isolated rat bile duct epithelial cells
    • Alvaro, D., W. K. C. Cho, A. Mennone, and J. L. Boyer. Effect of secretin on intracellular pH regulation in isolated rat bile duct epithelial cells. J. Clin. Invest. 92: 1314-1325, 1993.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1314-1325
    • Alvaro, D.1    Cho, W.K.C.2    Mennone, A.3    Boyer, J.L.4
  • 10
    • 0029976124 scopus 로고    scopus 로고
    • A morphometric study of the epithelium lining the rat intrahepatic biliary tree
    • Benedetti, A., C. Bassotti, K. Rapino, and A. M. Jezequell. A morphometric study of the epithelium lining the rat intrahepatic biliary tree. J. Hepatol. 24: 335-342, 1996.
    • (1996) J. Hepatol. , vol.24 , pp. 335-342
    • Benedetti, A.1    Bassotti, C.2    Rapino, K.3    Jezequell, A.M.4
  • 11
    • 0020973213 scopus 로고
    • Proteins involved in the membrane-cytoskeleton association in human erythrocytes: Spectrin, ankyrin and band 3
    • Bennet, V. Proteins involved in the membrane-cytoskeleton association in human erythrocytes: spectrin, ankyrin and band 3. Methods Enzymol. 96: 313-324, 1983.
    • (1983) Methods Enzymol. , vol.96 , pp. 313-324
    • Bennet, V.1
  • 12
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction
    • Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 13
    • 0024550243 scopus 로고
    • Morphological heterogeneity along the rat inner medullary collecting duct
    • Clapp, W. L., K. M. Madsen, J. W. Verlander, and C. G. Tisher. Morphological heterogeneity along the rat inner medullary collecting duct. Lab. Invest. 60: 219-230, 1989.
    • (1989) Lab. Invest. , vol.60 , pp. 219-230
    • Clapp, W.L.1    Madsen, K.M.2    Verlander, J.W.3    Tisher, C.G.4
  • 14
    • 0026545547 scopus 로고
    • Characterization of the cystic transmembrane conductance regulator in a colonocyte cell line
    • Cohn, J. A., A. C. Nairn, C. R. Marino, D. Melhus, and J. Kole. Characterization of the cystic transmembrane conductance regulator in a colonocyte cell line. Proc. Natl. Acad. Sci. USA 89: 2340-2344, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2340-2344
    • Cohn, J.A.1    Nairn, A.C.2    Marino, C.R.3    Melhus, D.4    Kole, J.5
  • 15
    • 0027134853 scopus 로고
    • Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells
    • Cohn, J. A., T. V. Strong, M. R. Picciotto, A. C. Nairn, F. S. Collins, and J. G. Fitz. Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells. Gastroenterology 105: 1857-1864, 1993.
    • (1993) Gastroenterology , vol.105 , pp. 1857-1864
    • Cohn, J.A.1    Strong, T.V.2    Picciotto, M.R.3    Nairn, A.C.4    Collins, F.S.5    Fitz, J.G.6
  • 16
    • 0026688632 scopus 로고
    • Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium
    • Cohn, S., T. Simon, K. Roth, E. Birkenmeier, and J. Gordon. Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium. J. Cell Biol. 119: 27-44, 1992.
    • (1992) J. Cell Biol. , vol.119 , pp. 27-44
    • Cohn, S.1    Simon, T.2    Roth, K.3    Birkenmeier, E.4    Gordon, J.5
  • 17
    • 0027523995 scopus 로고
    • Regulation of membrane chloride currents in rat bile duct epithelial cells
    • Fitz, J. G., S. Basavappa, J. McGill, O. Melhus, and J. A. Cohn. Regulation of membrane chloride currents in rat bile duct epithelial cells. J. Clin. Invest. 91: 319-328, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 319-328
    • Fitz, J.G.1    Basavappa, S.2    McGill, J.3    Melhus, O.4    Cohn, J.A.5
  • 19
    • 0022004930 scopus 로고
    • Monoclonal antibodies recognizing oval cells induced in the liver of rats by N-2-fluorenylacetamide or ethionine and a choline-deficient diet
    • Hixson, D. C., and J. P. Allison. Monoclonal antibodies recognizing oval cells induced in the liver of rats by N-2-fluorenylacetamide or ethionine and a choline-deficient diet. Cancer Res. 45: 3750-3760, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 3750-3760
    • Hixson, D.C.1    Allison, J.P.2
  • 20
    • 0024441370 scopus 로고
    • Isolation and morphological characterization of bile duct epithelial cells from normal rat liver
    • Ishii, M., B. Vroman, and N. F. LaRusso. Isolation and morphological characterization of bile duct epithelial cells from normal rat liver. Gastroenterology 97: 1236-1247, 1989.
    • (1989) Gastroenterology , vol.97 , pp. 1236-1247
    • Ishii, M.1    Vroman, B.2    LaRusso, N.F.3
  • 21
    • 0026710665 scopus 로고
    • Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism
    • Kato, A., G. J. Gores, and N. F. LaRusso. Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism. J. Biol. Chem. 267: 15523-15529, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 15523-15529
    • Kato, A.1    Gores, G.J.2    LaRusso, N.F.3
  • 23
    • 0023109812 scopus 로고
    • The effect of secretin on bile flow and bile acid and bilirubin excretion following relief of prolonged bile duct obstruction in the rat
    • Kountouras, J., S. McKavanagh, M. Burmicky, and B. H. Billing. The effect of secretin on bile flow and bile acid and bilirubin excretion following relief of prolonged bile duct obstruction in the rat. J. Hepatol. 4: 198-205, 1986.
    • (1986) J. Hepatol. , vol.4 , pp. 198-205
    • Kountouras, J.1    McKavanagh, S.2    Burmicky, M.3    Billing, B.H.4
  • 24
    • 0026787649 scopus 로고
    • Secretin stimulates bile ductular secretory activity through the cAMP system
    • Gastrointest. Liver Physiol. 26
    • Lenzen, R., G. Alpini, and N. Tavoloni. Secretin stimulates bile ductular secretory activity through the cAMP system. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G527-G532, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Lenzen, R.1    Alpini, G.2    Tavoloni, N.3
  • 25
    • 0025687701 scopus 로고
    • Von Willebrand factor antigen is not an accurate marker of rat and guinea pig liver endothelial cells
    • Lenzi, R., G. Alpini, M. H. Liu, J. H. Rand, and N. Tavoloni. Von Willebrand factor antigen is not an accurate marker of rat and guinea pig liver endothelial cells. Liver 10: 372-379, 1990.
    • (1990) Liver , vol.10 , pp. 372-379
    • Lenzi, R.1    Alpini, G.2    Liu, M.H.3    Rand, J.H.4    Tavoloni, N.5
  • 26
    • 0000636490 scopus 로고    scopus 로고
    • 70% Partial hepatectomy induces proliferative and secretory events in small cholangiocytes
    • LeSage, G., S. S. Glaser, W. Robertson, J. L. Phonizy, R. Rodgers, and G. Alpini. 70% Partial hepatectomy induces proliferative and secretory events in small cholangiocytes (Abstract). Gastroenterology 110: A1251, 1996.
    • (1996) Gastroenterology , vol.110
    • LeSage, G.1    Glaser, S.S.2    Robertson, W.3    Phonizy, J.L.4    Rodgers, R.5    Alpini, G.6
  • 27
    • 0023632268 scopus 로고
    • New concepts in biliary cirrhosis
    • Ludwig, J. New concepts in biliary cirrhosis. Semin. Liv. Dis. 7: 293-301, 1987.
    • (1987) Semin. Liv. Dis. , vol.7 , pp. 293-301
    • Ludwig, J.1
  • 28
    • 26844560159 scopus 로고
    • Expression of proliferating cell nuclear antigen (PCNA) in normal liver
    • Mancini, R., R. Bassotti, A. M. Jezequel, and F. Orlandi. Expression of proliferating cell nuclear antigen (PCNA) in normal liver (Abstract). Gastroenterology 102: A847, 1992.
    • (1992) Gastroenterology , vol.102
    • Mancini, R.1    Bassotti, R.2    Jezequel, A.M.3    Orlandi, F.4
  • 29
    • 84989554808 scopus 로고
    • Immunohistochemical detection of chloride/bicarbonate anion exchangers in human liver
    • Martínez-Ansó, E., J. E. Castillo, J. Díez, J. F. Medina, and J. Prieto. Immunohistochemical detection of chloride/bicarbonate anion exchangers in human liver. Hepatology 19: 1400-1406, 1994.
    • (1994) Hepatology , vol.19 , pp. 1400-1406
    • Martínez-Ansó, E.1    Castillo, J.E.2    Díez, J.3    Medina, J.F.4    Prieto, J.5
  • 30
    • 0024581801 scopus 로고
    • Enzyme profile of rat bile ductular epithelial cells in reference to the resistance phenotype in hepatocarcinogenesis
    • Mathis, G. A., S. A. Walls, P. D'Amico, T. F. Gengo, and A. E. Sirica. Enzyme profile of rat bile ductular epithelial cells in reference to the resistance phenotype in hepatocarcinogenesis. Hepatology 9: 477-485, 1989.
    • (1989) Hepatology , vol.9 , pp. 477-485
    • Mathis, G.A.1    Walls, S.A.2    D'Amico, P.3    Gengo, T.F.4    Sirica, A.E.5
  • 31
    • 0026027865 scopus 로고
    • Expression of multiple proteins structurally related to γ-glutamyl transpeptidase in non-neoplastic adult rat hepatocytes in vivo and in culture
    • Mathis, G. A., P. A. Wyss, E. G. Schuetz, R. P. Hughey, and A. E. Sirica. Expression of multiple proteins structurally related to γ-glutamyl transpeptidase in non-neoplastic adult rat hepatocytes in vivo and in culture. J. Cell. Physiol. 146: 234-241, 1991.
    • (1991) J. Cell. Physiol. , vol.146 , pp. 234-241
    • Mathis, G.A.1    Wyss, P.A.2    Schuetz, E.G.3    Hughey, R.P.4    Sirica, A.E.5
  • 32
    • 0028355830 scopus 로고
    • - channels in bile duct epithelial cells through a cAMP-dependent mechanism
    • Gastrointest. Liver Physiol. 29
    • - channels in bile duct epithelial cells through a cAMP-dependent mechanism. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G731-G736, 1994.
    • (1994) Am. J. Physiol. , vol.266
    • McGill, J.M.1    Basavappa, S.2    Gettys, T.W.3    Fitz, J.G.4
  • 33
    • 0029090214 scopus 로고
    • Expression and localization of the cystic fibrosis transmembrane conductance regulator mRNA and its protein in rat brain
    • Mulberg, A. E., L. P. Resta, E. B. Wiedner, S. M. Altschuler, D. M. Jefferson, and D. L. Broussard. Expression and localization of the cystic fibrosis transmembrane conductance regulator mRNA and its protein in rat brain. J. Clin. Invest. 96: 646-652, 1995.
    • (1995) J. Clin. Invest. , vol.96 , pp. 646-652
    • Mulberg, A.E.1    Resta, L.P.2    Wiedner, E.B.3    Altschuler, S.M.4    Jefferson, D.M.5    Broussard, D.L.6
  • 35
    • 0027475944 scopus 로고
    • CHIP28 water channels are localized in constitutively water-permeable segments of the nephron
    • Nielsen, S., B. L. Smith, E. I. Christensen, M. A. Knepper, and P. Agre. CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. J. Cell Biol. 120: 371-383, 1993.
    • (1993) J. Cell Biol. , vol.120 , pp. 371-383
    • Nielsen, S.1    Smith, B.L.2    Christensen, E.I.3    Knepper, M.A.4    Agre, P.5
  • 40
    • 0028011868 scopus 로고
    • Neoexpression of Lewis Y antigen is a sensitive phenotypic change of the damaged intrahepatic bile ducts
    • Sasaki, M., N. Kono, and Y. Nakanuma. Neoexpression of Lewis Y antigen is a sensitive phenotypic change of the damaged intrahepatic bile ducts. Hepatology 19: 138-144, 1994.
    • (1994) Hepatology , vol.19 , pp. 138-144
    • Sasaki, M.1    Kono, N.2    Nakanuma, Y.3
  • 41
    • 0000985417 scopus 로고
    • Electron microscopic studies of normal and proliferated bile ductules
    • Schaffner, F., and H. Popper. Electron microscopic studies of normal and proliferated bile ductules. Am. J. Pathol. 138: 393-410, 1961.
    • (1961) Am. J. Pathol. , vol.138 , pp. 393-410
    • Schaffner, F.1    Popper, H.2
  • 42
    • 0025277595 scopus 로고
    • Origin, pattern and mechanism of bile duct proliferation following biliary obstruction in the rat
    • Slott, P. A., M. H. Liu, and N. Tavoloni. Origin, pattern and mechanism of bile duct proliferation following biliary obstruction in the rat. Gastroenterology 98: 466-477, 1990.
    • (1990) Gastroenterology , vol.98 , pp. 466-477
    • Slott, P.A.1    Liu, M.H.2    Tavoloni, N.3
  • 43
    • 0028872272 scopus 로고
    • Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes
    • Gastrointest. Liver Physiol. 32
    • Tietz, P., G. Alpini, L. Pham, and N. LaRusso. Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G110-G118, 1995.
    • (1995) Am. J. Physiol. , vol.269
    • Tietz, P.1    Alpini, G.2    Pham, L.3    LaRusso, N.4
  • 46
    • 0027365544 scopus 로고
    • Phenotypic heterogeneity within clonogenic ductal cell populations isolated from normal adult rat liver
    • Yang, L., R. A. Faris, and D. C. Hixson. Phenotypic heterogeneity within clonogenic ductal cell populations isolated from normal adult rat liver. Proc. Soc. Exp. Biol. Med. 204: 280-288, 1993.
    • (1993) Proc. Soc. Exp. Biol. Med. , vol.204 , pp. 280-288
    • Yang, L.1    Faris, R.A.2    Hixson, D.C.3
  • 47
    • 0018179381 scopus 로고
    • Morphological characterization of Kupffer and endothelial cells of rat liver isolated by counterflow elutriation
    • Zahlten, R. N., H. K. Hagler, M. E. Nejtek, and C. J. Day. Morphological characterization of Kupffer and endothelial cells of rat liver isolated by counterflow elutriation. Gastroenterology 75: 80-87, 1978.
    • (1978) Gastroenterology , vol.75 , pp. 80-87
    • Zahlten, R.N.1    Hagler, H.K.2    Nejtek, M.E.3    Day, C.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.