Pharmacokinetics of honokiol after intravenous guttae in beagle dogs assessed using ultra-performance liquid chromatography-tandem mass spectrometry

Biomedical Chromatography

Volumn 28, Issue 10, 2014, Pages 1378-1383

  Liang, Yi ^a   Cui, Gang ^b   Wang, Xiaoxue ^b   Zhang, Wei ^c   An, Quan ^c   Lin, Zongtao ^a   Wang, Hong ^a   Chen, Shizhong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^c CHINA INSTITUTE FOR RADIATION PROTECTION   (China)

Author keywords

Beagle dog; Honokiol; Pharmacokinetics; Plasma; UPLC MS MS

Indexed keywords

ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL;

BEAGLE DOG; DOG PLASMA; HONOKIOL; INTERNAL STANDARDS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; MAGNOLOL; SIMPLE++; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS/MS;

PHARMACOKINETICS;

HONOKIOL; MAGNOLOL; METHANOL; WATER; BIPHENYL DERIVATIVE; LIGNAN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BEAGLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STABILITY; ELECTROSPRAY; ELUTION; FEMALE; FLOW RATE; FREEZE THAWING; MALE; MASS SPECTROMETER; MEAN RESIDENCE TIME; MICROEMULSION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; TANDEM MASS SPECTROMETRY; TEMPERATURE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VOLUME OF DISTRIBUTION AT STEADY-STATE; ANIMAL; BLOOD; CHEMISTRY; DOG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

ADMINISTRATION, INTRAVENOUS; ANIMALS; BIPHENYL COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; FEMALE; LIGNANS; LINEAR MODELS; MALE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84908370801     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3179     Document Type: Article

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