Simultaneous determination of honokiol and magnolol in magnolia officinalis by liquid chromatography with tandem mass spectrometric detection

Biomedical Chromatography

Volumn 20, Issue 10, 2006, Pages 1076-1081

  Wu, Yu Tse ^a   Lin, Lie Chwen ^b   Tsai, Tung Hu ^a,c,d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Honokiol; Liquid chromatography mass spectrometry; Magnolol

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; MASS SPECTROMETERS; MASS SPECTROMETRY;

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHODS; HONOKIOL; LC-MS-MS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; MAGNOLOL; MOBILE PHASIS; REVERSED PHASE; SELECTED REACTION MONITORING; SIMULTANEOUS DETERMINATIONS; TANDEM MASS SPECTROMETRIC DETECTION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACETONITRILE; HONOKIOL; MAGNOLIA OFFICINALIS EXTRACT; MAGNOLOL; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; FLOW RATE; INTERMETHOD COMPARISON; ION PAIR EXTRACTION; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; MAGNOLIA OFFICINALIS; MAGNOLIACEAE; NONHUMAN; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

MAGNOLIA OFFICINALIS;

EID: 33750694963     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.644     Document Type: Article

References (15)

1. Akira K, Satoshi K, Hideki H, Dongri J and Fumiyo K. Determination of honokiol and magnolol by micro HPLC with electrochemical detection and its application to the distribution analysis in branches and leaves of Magnolia obovata. Chemical and Pharmaceutical Bulletin 2005; 53: 319.
2. Chou CYC, Tsai TH, Lin MF and Chen CF. Simutaneous determination of honokiol and magnolol in Magnolia officinalis by capillary zone electrophoresis. Journal of Liquid Chromatography 1996; 19: 1909.
3. Clark AM, EI-Feraly FS and Li WS. Antimicrobial activity of phenolic constituents of Magnolia grandiflora L. Journal of Pharmaceutical Science 1981; 70: 951.
4. Fujita M, Itokawa H and Sashida Y. Studies on the components of Magnolia obovata Thunb. 3. Occurrence of magnolol and honokiol in M. obovata and other allied plants. Yakugaku Zasshi 1973; 93: 429.
5. Juangsu New Medical College. Zhong Yao Da Ci Dian (Dictionary of Chinese Material Medica). Shanghai Scientific and Technological Publishers: Shanghai, 1985.
6. Lee YC, Huang CY, Wen KC and Suen TT. Determination of liquiritin, glycyrrhizin, hesperidin, cinnamic acid, cinnamaldehyde, honokiol and magnolol in the traditional Chinese medicinal preparation Wuu-Ji-San by high-performance liquid chromatography. Journal of Chromatography A 1995; 692: 137.
7. Li Y, Xu C, Zhang Q, Liu JY and Tan RX In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases. Journal of Ethnopharmacology 2005; 98: 329.
8. Lo YC, Teng CM, Chen CF, Chen CC and Hong CY. Magnolol and honokiol isolated from magnolia officinalis protect rat heart mitochondria against lipid peroxidation Biochemical Pharmacology 1994; 47: 549.
9. Sheu SJ and Lu CF. Determination of eight constituents of Hsiaocheng-chi-tang by high-performance liquid chromatography. Journal of Chromatography A 1995; 704: 518.
10. Shoji Y, Takashi N, Akihide K, Toshihiro N and Itsuo N. Isolation and characterization of phenolic compounds from Magnoliae Cortex produced in China. Chemical and Pharmaceutical Bulletin 1991; 39: 2024.
11. Teng CM, Chen CC, Ko IN, Lee LG, Huang TF and Chen YP. Two antiplatelet agents from magnolia officinalis. Thrombosis Research 1988; 50: 757.
12. Tsai TH and Chen CF. Identification and determination of honokiol and magnolol from Magnolia officinalis by high-performance liquid chromatography with photodiode-array UV detection. Journal of Chromatography 1992; 598: 143.
13. Ueda J, Momma N and Ohsawa K. A simultaneous determination of honokiol and magnolol in oriental pharmaceutical decoctions containing magnolia bark by ion-pair high-performance liquid chromatography. Yakugaku Zasshi 1993; 10: 155.
14. Yang SE, Hsieh MT, Tsai TH and Hsu SL. Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells. Biochemical Pharmacology 2002; 63: 1641.
15. Yang SE, Hsieh MT, Tsai TH and Hsu SL. Effector mechanism of magnolol-induced apoptosis in human lung squamous carcinoma CH27 cells. British Journal of Pharmacology 2003; 138: 193.