Benzodiazepine ligands rapidly influence GABAA receptor diffusion and clustering at hippocampal inhibitory synapses

Neuropharmacology

Volumn 88, Issue , 2015, Pages 199-208

  Lévi, Sabine ^a,b,c   Le Roux, Nicolas ^a,b,c   Eugène, Emmanuel ^a,b,c   Poncer, Jean Christophe ^a,b,c  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c INSTITUT DU FER À MOULIN   (France)

Author keywords

GABA; Hippocampus; Receptor clustering; Single particle tracking; Synaptic inhibition

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; DIAZEPAM; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CARBOLINE DERIVATIVE; CARRIER PROTEIN; GEPHYRIN; MEMBRANE PROTEIN; METHYL 6,7-DIMETHOXY-4-ETHYL-BETA-CARBOLINE-3-CARBOXYLATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GABAERGIC TRANSMISSION; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; LIGAND BINDING; MOLECULAR IMAGING; NERVE CELL; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; SYNAPTIC INHIBITION; ANIMAL; CELL CULTURE; CONFOCAL MICROSCOPY; DIFFUSION; DRUG EFFECTS; EPILUMINESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; MICROELECTRODE; MINIATURE ENDPLATE POTENTIAL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SYNAPSE;

ANIMALS; CARBOLINES; CARRIER PROTEINS; CELLS, CULTURED; DERMOSCOPY; DIAZEPAM; DIFFUSION; GABA MODULATORS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIALS; MEMBRANE PROTEINS; MICROELECTRODES; MICROSCOPY, CONFOCAL; MINIATURE POSTSYNAPTIC POTENTIALS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SYNAPSES; TRANSFECTION;

EID: 84908368289     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.06.002     Document Type: Article

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