메뉴 건너뛰기




Volumn 10, Issue 10, 2014, Pages

Robust Identification of Noncoding RNA from Transcriptomes Requires Phylogenetically-Informed Sampling

Author keywords

[No Author keywords available]

Indexed keywords

ENVIRONMENTAL REGULATIONS; GENES; PHYLOGENETIC;

EID: 84908336343     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003907     Document Type: Article
Times cited : (34)

References (68)
  • 1
    • 72949101201 scopus 로고    scopus 로고
    • A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea
    • Wu D, Hugenholtz P, Mavromatis K, Pukall R, Dalin E, et al. (2009) A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea. Nature 462: 1056–60.
    • (2009) Nature , vol.462 , pp. 1056-1060
    • Wu, D.1    Hugenholtz, P.2    Mavromatis, K.3    Pukall, R.4    Dalin, E.5
  • 2
    • 84881138595 scopus 로고    scopus 로고
    • Insights into the phylogeny and coding potential of microbial dark matter
    • Rinke C, Schwientek P, Sczyrba A, Ivanova NN, Anderson IJ, et al. (2013) Insights into the phylogeny and coding potential of microbial dark matter. Nature 499: 431–7.
    • (2013) Nature , vol.499 , pp. 431-437
    • Rinke, C.1    Schwientek, P.2    Sczyrba, A.3    Ivanova, N.N.4    Anderson, I.J.5
  • 3
    • 84865179264 scopus 로고    scopus 로고
    • High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity
    • Loman NJ, Constantinidou C, Chan JZ, Halachev M, Sergeant M, et al. (2012) High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity. Nat Rev Microbiol 10: 599–606.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 599-606
    • Loman, N.J.1    Constantinidou, C.2    Chan, J.Z.3    Halachev, M.4    Sergeant, M.5
  • 4
    • 84893495798 scopus 로고    scopus 로고
    • Integrating genomics into the taxonomy and systematics of the Bacteria and Archaea
    • Chun J, Rainey FA, (2014) Integrating genomics into the taxonomy and systematics of the Bacteria and Archaea. Int J Syst Evol Microbiol 64: 316–24.
    • (2014) Int J Syst Evol Microbiol , vol.64 , pp. 316-324
    • Chun, J.1    Rainey, F.A.2
  • 5
    • 80053905327 scopus 로고    scopus 로고
    • Bacterial genomes: from regulatory complexity to engineering
    • Sorek R, Serrano L, (2011) Bacterial genomes: from regulatory complexity to engineering. Curr Opin Microbiol 14: 577–8.
    • (2011) Curr Opin Microbiol , vol.14 , pp. 577-578
    • Sorek, R.1    Serrano, L.2
  • 6
    • 80053019485 scopus 로고    scopus 로고
    • Regulation by small RNAs in bacteria: expanding frontiers
    • Storz G, Vogel J, Wassarman KM, (2011) Regulation by small RNAs in bacteria: expanding frontiers. Mol Cell 43: 880–91.
    • (2011) Mol Cell , vol.43 , pp. 880-891
    • Storz, G.1    Vogel, J.2    Wassarman, K.M.3
  • 7
    • 0034999985 scopus 로고    scopus 로고
    • A guided tour: small RNA function in Archaea
    • Dennis PP, Omer A, Lowe T, (2001) A guided tour: small RNA function in Archaea. Mol Microbiol 40: 509–19.
    • (2001) Mol Microbiol , vol.40 , pp. 509-519
    • Dennis, P.P.1    Omer, A.2    Lowe, T.3
  • 8
    • 74249095519 scopus 로고    scopus 로고
    • CRISPR/Cas, the immune system of bacteria and archaea
    • Horvath P, Barrangou R, (2010) CRISPR/Cas, the immune system of bacteria and archaea. Science 327: 167–70.
    • (2010) Science , vol.327 , pp. 167-170
    • Horvath, P.1    Barrangou, R.2
  • 10
    • 84897128298 scopus 로고    scopus 로고
    • The noncoding RNA revolution-trashing old rules to forge new ones
    • Cech TR, Steitz JA, (2014) The noncoding RNA revolution-trashing old rules to forge new ones. Cell 157: 77–94.
    • (2014) Cell , vol.157 , pp. 77-94
    • Cech, T.R.1    Steitz, J.A.2
  • 11
    • 84859165788 scopus 로고    scopus 로고
    • The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata
    • Pagani I, Liolios K, Jansson J, Chen IM, Smirnova T, et al. (2012) The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata. Nucleic Acids Res 40: 571–9.
    • (2012) Nucleic Acids Res , vol.40 , pp. 9-571
    • Pagani, I.1    Liolios, K.2    Jansson, J.3    Chen, I.M.4    Smirnova, T.5
  • 12
    • 84866332775 scopus 로고    scopus 로고
    • Growing unculturable bacteria
    • Stewart EJ, (2012) Growing unculturable bacteria. J Bacteriol 194: 4151–60.
    • (2012) J Bacteriol , vol.194 , pp. 4151-4160
    • Stewart, E.J.1
  • 15
    • 1542377296 scopus 로고    scopus 로고
    • Community structure and metabolism through reconstruction of microbial genomes from the environment
    • Tyson GW, Chapman J, Hugenholtz P, Allen EE, Ram RJ, et al. (2004) Community structure and metabolism through reconstruction of microbial genomes from the environment. Nature 428: 37–43.
    • (2004) Nature , vol.428 , pp. 37-43
    • Tyson, G.W.1    Chapman, J.2    Hugenholtz, P.3    Allen, E.E.4    Ram, R.J.5
  • 16
    • 33750431080 scopus 로고    scopus 로고
    • Symbiosis insights through metagenomic analysis of a microbial consortium
    • Woyke T, Teeling H, Ivanova NN, Huntemann M, Richter M, et al. (2006) Symbiosis insights through metagenomic analysis of a microbial consortium. Nature 443: 950–5.
    • (2006) Nature , vol.443 , pp. 950-955
    • Woyke, T.1    Teeling, H.2    Ivanova, N.N.3    Huntemann, M.4    Richter, M.5
  • 17
    • 84908338331 scopus 로고    scopus 로고
    • RNA-mediated control of bacterial gene expression: role of regulatory non-coding RNAs. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Wiley-VCH Verlag GmbH & Co
    • Mandin P, Toledo-Arana A, Fouquier d'Hérouel A, Repoila F (2013) RNA-mediated control of bacterial gene expression: role of regulatory non-coding RNAs. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Wiley-VCH Verlag GmbH & Co. KGaA, pp.1–36.
    • (2013) KGaA , pp. 1-36
    • Mandin, P.1    Toledo-Arana, A.2    Fouquier D'hérouel, A.3    Repoila, F.4
  • 18
    • 33845986334 scopus 로고    scopus 로고
    • Exploring genomic dark matter: a critical assessment of the performance of homology search methods on noncoding RNA
    • Freyhult EK, Bollback JP, Gardner PP, (2007) Exploring genomic dark matter: a critical assessment of the performance of homology search methods on noncoding RNA. Genome Res 17: 117–125.
    • (2007) Genome Res , vol.17 , pp. 117-125
    • Freyhult, E.K.1    Bollback, J.P.2    Gardner, P.P.3
  • 19
    • 65549111754 scopus 로고    scopus 로고
    • Infernal 1.0: inference of RNA alignments
    • Nawrocki EP, Kolbe DL, Eddy SR, (2009) Infernal 1.0: inference of RNA alignments. Bioinformatics 25: 1335–7.
    • (2009) Bioinformatics , vol.25 , pp. 1335-1337
    • Nawrocki, E.P.1    Kolbe, D.L.2    Eddy, S.R.3
  • 20
    • 46349083026 scopus 로고    scopus 로고
    • The distributions, mechanisms, and structures of metabolite-binding riboswitches
    • Barrick JE, Breaker RR, (2007) The distributions, mechanisms, and structures of metabolite-binding riboswitches. Genome Biol 8: R239.
    • (2007) Genome Biol , vol.8 , pp. R239
    • Barrick, J.E.1    Breaker, R.R.2
  • 21
    • 0032584643 scopus 로고    scopus 로고
    • An integrated model of the transcription complex in elongation, termination, and editing
    • von Hippel PH, (1998) An integrated model of the transcription complex in elongation, termination, and editing. Science 281: 660–5.
    • (1998) Science , vol.281 , pp. 660-665
    • Von Hippel, P.H.1
  • 23
    • 79954597274 scopus 로고    scopus 로고
    • Termination and antitermination: RNA polymerase runs a stop sign
    • Santangelo TJ, Artsimovitch I, (2011) Termination and antitermination: RNA polymerase runs a stop sign. Nat Rev Microbiol 9: 319–29.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 319-329
    • Santangelo, T.J.1    Artsimovitch, I.2
  • 24
    • 0020417286 scopus 로고
    • Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena
    • Kruger K, Grabowski PJ, Zaug AJ, Sands J, Gottschling DE, et al. (1982) Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell 31: 147–57.
    • (1982) Cell , vol.31 , pp. 147-157
    • Kruger, K.1    Grabowski, P.J.2    Zaug, A.J.3    Sands, J.4    Gottschling, D.E.5
  • 25
    • 0021013526 scopus 로고
    • The RNA moiety of Ribonuclease P is the catalytic subunit of the enzyme
    • Guerrier-Takada C, Gardiner K, Marsh T, Pace N, Altman S, (1983) The RNA moiety of Ribonuclease P is the catalytic subunit of the enzyme. Cell 35: 849–57.
    • (1983) Cell , vol.35 , pp. 849-857
    • Guerrier-Takada, C.1    Gardiner, K.2    Marsh, T.3    Pace, N.4    Altman, S.5
  • 26
    • 1642586299 scopus 로고    scopus 로고
    • Control of gene expression by a natural metabolite-responsive ribozyme
    • Winkler WC, Nahvi A, Roth A, Collins JA, Breaker RR, (2004) Control of gene expression by a natural metabolite-responsive ribozyme. Nature 428: 281–6.
    • (2004) Nature , vol.428 , pp. 281-286
    • Winkler, W.C.1    Nahvi, A.2    Roth, A.3    Collins, J.A.4    Breaker, R.R.5
  • 27
    • 84891008536 scopus 로고    scopus 로고
    • A widespread self-cleaving ribozyme class is revealed by bioinformatics
    • Roth A, Weinberg Z, Chen AG, Kim PB, Ames TD, et al. (2014) A widespread self-cleaving ribozyme class is revealed by bioinformatics. Nat Chem Biol 10: 56–60.
    • (2014) Nat Chem Biol , vol.10 , pp. 56-60
    • Roth, A.1    Weinberg, Z.2    Chen, A.G.3    Kim, P.B.4    Ames, T.D.5
  • 28
    • 34047118522 scopus 로고    scopus 로고
    • CRISPR provides acquired resistance against viruses in prokaryotes
    • Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, et al. (2007) CRISPR provides acquired resistance against viruses in prokaryotes. Science 315: 1709–12.
    • (2007) Science , vol.315 , pp. 1709-1712
    • Barrangou, R.1    Fremaux, C.2    Deveau, H.3    Richards, M.4    Boyaval, P.5
  • 31
    • 84885611420 scopus 로고    scopus 로고
    • Temperature triggers immune evasion by Neisseria meningitidis
    • Loh E, Kugelberg E, Tracy A, Zhang Q, Gollan B, et al. (2013) Temperature triggers immune evasion by Neisseria meningitidis. Nature 502: 237–40.
    • (2013) Nature , vol.502 , pp. 237-240
    • Loh, E.1    Kugelberg, E.2    Tracy, A.3    Zhang, Q.4    Gollan, B.5
  • 33
    • 0034615782 scopus 로고    scopus 로고
    • Archaeal homologs of eukaryotic methylation guide small nucleolar RNAs: lessons from the Pyrococcus genomes
    • Gaspin C, Cavaillé J, Erauso G, Bachellerie JP, (2000) Archaeal homologs of eukaryotic methylation guide small nucleolar RNAs: lessons from the Pyrococcus genomes. J Mol Biol 297: 895–906.
    • (2000) J Mol Biol , vol.297 , pp. 895-906
    • Gaspin, C.1    Cavaillé, J.2    Erauso, G.3    Bachellerie, J.P.4
  • 34
    • 76149132968 scopus 로고    scopus 로고
    • SnoPatrol: how many snoRNA genes are there?
    • Gardner PP, Bateman A, Poole AM, (2010) SnoPatrol: how many snoRNA genes are there? J Biol 9: 4.
    • (2010) J Biol , vol.9 , pp. 4
    • Gardner, P.P.1    Bateman, A.2    Poole, A.M.3
  • 36
    • 84870448969 scopus 로고    scopus 로고
    • Comparative analysis of RNA families reveals distinct repertoires for each domain of life
    • Hoeppner MP, Gardner PP, Poole AM, (2012) Comparative analysis of RNA families reveals distinct repertoires for each domain of life. PLoS Comput Biol 8: e1002752.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002752
    • Hoeppner, M.P.1    Gardner, P.P.2    Poole, A.M.3
  • 37
    • 77957802374 scopus 로고    scopus 로고
    • Studying bacterial transcriptomes using RNA-seq
    • Croucher NJ, Thomson NR, (2010) Studying bacterial transcriptomes using RNA-seq. Curr Opin Microbiol 13: 619–24.
    • (2010) Curr Opin Microbiol , vol.13 , pp. 619-624
    • Croucher, N.J.1    Thomson, N.R.2
  • 38
    • 84879413726 scopus 로고    scopus 로고
    • Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms
    • van Opijnen T, Camilli A, (2013) Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms. Nat Rev Microbiol 11: 435–42.
    • (2013) Nat Rev Microbiol , vol.11 , pp. 435-442
    • Van Opijnen, T.1    Camilli, A.2
  • 39
    • 84880876168 scopus 로고    scopus 로고
    • Approaches to querying bacterial genomes with transposon-insertion sequencing
    • Barquist L, Boinett CJ, Cain AK, (2013) Approaches to querying bacterial genomes with transposon-insertion sequencing. RNA Biol 10: 1161–9.
    • (2013) RNA Biol , vol.10 , pp. 1161-1169
    • Barquist, L.1    Boinett, C.J.2    Cain, A.K.3
  • 40
    • 84877290776 scopus 로고    scopus 로고
    • A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium
    • Barquist L, Langridge GC, Turner DJ, Phan MD, Turner AK, et al. (2013) A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium. Nucleic Acids Res 41: 4549–64.
    • (2013) Nucleic Acids Res , vol.41 , pp. 4549-4564
    • Barquist, L.1    Langridge, G.C.2    Turner, D.J.3    Phan, M.D.4    Turner, A.K.5
  • 43
    • 0242317680 scopus 로고    scopus 로고
    • Computational identification of non-coding rnas in saccharomyces cerevisiae by comparative genomics
    • McCutcheon JP, Eddy SR, (2003) Computational identification of non-coding rnas in saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31: 4119–28.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4119-4128
    • McCutcheon, J.P.1    Eddy, S.R.2
  • 44
    • 0042667165 scopus 로고    scopus 로고
    • Essentiality, not expressiveness, drives gene-strand bias in bacteria
    • Rocha EP, Danchin A, (2003) Essentiality, not expressiveness, drives gene-strand bias in bacteria. Nat Genet 34: 377–8.
    • (2003) Nat Genet , vol.34 , pp. 377-378
    • Rocha, E.P.1    Danchin, A.2
  • 45
    • 0034978556 scopus 로고    scopus 로고
    • Highly expressed genes in yeast evolve slowly
    • Pál C, Papp B, Hurst LD, (2001) Highly expressed genes in yeast evolve slowly. Genetics 158: 927–31.
    • (2001) Genetics , vol.158 , pp. 927-931
    • Pál, C.1    Papp, B.2    Hurst, L.D.3
  • 47
    • 84863924309 scopus 로고    scopus 로고
    • Bacterial small RNA regulators: versatile roles and rapidly evolving variations
    • Gottesman S, Storz G, (2011) Bacterial small RNA regulators: versatile roles and rapidly evolving variations. Cold Spring Harb Perspect Biol 3: a003798.
    • (2011) Cold Spring Harb Perspect Biol , vol.3 , pp. a003798
    • Gottesman, S.1    Storz, G.2
  • 48
    • 14644390333 scopus 로고    scopus 로고
    • A model of the statistical power of comparative genome sequence analysis
    • Eddy SR, (2005) A model of the statistical power of comparative genome sequence analysis. PLoS Biol 3: e10.
    • (2005) PLoS Biol , vol.3 , pp. e10
    • Eddy, S.R.1
  • 49
    • 17844386108 scopus 로고    scopus 로고
    • A benchmark of multiple sequence alignment programs upon structural RNAs
    • Gardner PP, Wilm A, Washietl S, (2005) A benchmark of multiple sequence alignment programs upon structural RNAs. Nucleic Acids Res 33: 2433–9.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2433-2439
    • Gardner, P.P.1    Wilm, A.2    Washietl, S.3
  • 51
    • 24644462173 scopus 로고    scopus 로고
    • Accurate multiplex polony sequencing of an evolved bacterial genome
    • Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, et al. (2005) Accurate multiplex polony sequencing of an evolved bacterial genome. Science 309: 1728–32.
    • (2005) Science , vol.309 , pp. 1728-1732
    • Shendure, J.1    Porreca, G.J.2    Reppas, N.B.3    Lin, X.4    McCutcheon, J.P.5
  • 53
    • 24044455869 scopus 로고    scopus 로고
    • Genome sequencing in microfabricated high-density picolitre reactors
    • Margulies M, Egholm M, Altman WE, Attiya S, Bader JS, et al. (2005) Genome sequencing in microfabricated high-density picolitre reactors. Nature 437: 376–80.
    • (2005) Nature , vol.437 , pp. 376-380
    • Margulies, M.1    Egholm, M.2    Altman, W.E.3    Attiya, S.4    Bader, J.S.5
  • 54
    • 84863101693 scopus 로고    scopus 로고
    • AdapterRemoval: easy cleaning of next-generation sequencing reads
    • Lindgreen S, (2012) AdapterRemoval: easy cleaning of next-generation sequencing reads. BMC Res Notes 5: 337.
    • (2012) BMC Res Notes , vol.5 , pp. 337
    • Lindgreen, S.1
  • 55
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • Langmead B, Salzberg SL, (2012) Fast gapped-read alignment with Bowtie 2. Nat Methods 9: 357–9.
    • (2012) Nat Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 56
    • 70450177746 scopus 로고    scopus 로고
    • BFAST: an alignment tool for large scale genome resequencing
    • Homer N, Merriman B, Nelson SF, (2009) BFAST: an alignment tool for large scale genome resequencing. PLoS One 4: e7767.
    • (2009) PLoS One , vol.4 , pp. e7767
    • Homer, N.1    Merriman, B.2    Nelson, S.F.3
  • 57
    • 84890037468 scopus 로고    scopus 로고
    • Infernal 1.1: 100-fold faster RNA homology searches
    • Nawrocki EP, Eddy SR, (2013) Infernal 1.1: 100-fold faster RNA homology searches. Bioinformatics 29: 2933–5.
    • (2013) Bioinformatics , vol.29 , pp. 2933-2935
    • Nawrocki, E.P.1    Eddy, S.R.2
  • 59
    • 84892432106 scopus 로고    scopus 로고
    • nhmmer: DNA homology search with profile HMMs
    • Wheeler TJ, Eddy SR, (2013) nhmmer: DNA homology search with profile HMMs. Bioinformatics 29: 2487–9.
    • (2013) Bioinformatics , vol.29 , pp. 2487-2489
    • Wheeler, T.J.1    Eddy, S.R.2
  • 61
    • 4143149651 scopus 로고    scopus 로고
    • Consensus folding of aligned sequences as a new measure for the detection of functional RNAs by comparative genomics
    • Washietl S, Hofacker IL, (2004) Consensus folding of aligned sequences as a new measure for the detection of functional RNAs by comparative genomics. J Mol Biol 342: 19–30.
    • (2004) J Mol Biol , vol.342 , pp. 19-30
    • Washietl, S.1    Hofacker, I.L.2
  • 62
    • 79953009230 scopus 로고    scopus 로고
    • RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data
    • Washietl S, Findeiss S, Müller SA, Kalkhof S, von Bergen M, et al. (2011) RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data. RNA 17: 578–94.
    • (2011) RNA , vol.17 , pp. 578-594
    • Washietl, S.1    Findeiss, S.2    Müller, S.A.3    Kalkhof, S.4    Von Bergen, M.5
  • 63
    • 0003437302 scopus 로고    scopus 로고
    • Phylip (phylogeny inference package) version 3.6. Distributed by the author
    • Felsenstein J (2005) Phylip (phylogeny inference package) version 3.6. Distributed by the author. Department of Genome Sciences, University of Washington, Seattle.
    • (2005)
    • Felsenstein, J.1
  • 64
    • 0024307824 scopus 로고
    • Evaluation of the maximum likelihood estimate of the evolutionary tree topologies from DNA sequence data, and the branching order in hominoidea
    • Kishino H, Hasegawa M, (1989) Evaluation of the maximum likelihood estimate of the evolutionary tree topologies from DNA sequence data, and the branching order in hominoidea. J Mol Evol 29: 170–9.
    • (1989) J Mol Evol , vol.29 , pp. 170-179
    • Kishino, H.1    Hasegawa, M.2
  • 65
    • 0030034795 scopus 로고    scopus 로고
    • A Hidden Markov Model approach to variation among sites in rate of evolution
    • Felsenstein J, Churchill GA, (1996) A Hidden Markov Model approach to variation among sites in rate of evolution. Mol Biol Evol 13: 93–104.
    • (1996) Mol Biol Evol , vol.13 , pp. 93-104
    • Felsenstein, J.1    Churchill, G.A.2
  • 66
    • 84885819796 scopus 로고    scopus 로고
    • Systematic identification of gene families for use as “markers” for phylogenetic and phylogeny-driven ecological studies of bacteria and archaea and their major subgroups
    • Wu D, Jospin G, Eisen JA, (2013) Systematic identification of gene families for use as “markers” for phylogenetic and phylogeny-driven ecological studies of bacteria and archaea and their major subgroups. PLoS One 8: e77033.
    • (2013) PLoS One , vol.8 , pp. e77033
    • Wu, D.1    Jospin, G.2    Eisen, J.A.3
  • 67
    • 84895751645 scopus 로고    scopus 로고
    • PhyloSift: phylogenetic analysis of genomes and metagenomes
    • Darling AE, Jospin G, Lowe E, Matsen FA, Bik HM, et al. (2014) PhyloSift: phylogenetic analysis of genomes and metagenomes. PeerJ 2: e243.
    • (2014) PeerJ , vol.2 , pp. e243
    • Darling, A.E.1    Jospin, G.2    Lowe, E.3    Matsen, F.A.4    Bik, H.M.5
  • 68
    • 78650791283 scopus 로고    scopus 로고
    • R2R - software to speed the depiction of aesthetic consensus RNA secondary structures
    • Weinberg Z, Breaker RR, (2011) R2R - software to speed the depiction of aesthetic consensus RNA secondary structures. BMC Bioinformatics 12: 3.
    • (2011) BMC Bioinformatics , vol.12 , pp. 3
    • Weinberg, Z.1    Breaker, R.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.