Anti-HIV-1 activity of propolis in CD4+ lymphocyte and microglial cell cultures

Journal of Ethnopharmacology

Volumn 102, Issue 2, 2005, Pages 158-163

  Gekker, Genya ^a,b   Hu, Shuxian ^a,b   Spivak, Marla ^c   Lokensgard, James R ^a,b   Peterson, Phillip K ^a,b,d  

^a MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d HENNEPIN COUNTY MEDICAL CENTER   (United States)

Author keywords

AIDS; HIV 1; Honey bees; Propolis

Indexed keywords

INDINAVIR; PROPOLIS; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENTIATION; FETUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MICROGLIA; T LYMPHOCYTE;

ANTI-HIV AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV-1; HUMANS; MICROGLIA; PROPOLIS;

APINAE; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 26944448965     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2005.05.045     Document Type: Article

References (25)

1. M. Amoros, E. Lurton, J. Boustie, L. Girre, F. Sauvager, and M. Cormier Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate Journal of Natural Products 57 1994 644 647
2. K. Amres, F. Bucar, T. Kartnig, M. Witvrouw, C. Pannecouque, and E. De Clercq Antiviral activity against human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) of ethnobatanicaly selected Ethiopian medicinal Plants Phytotherapy Research 15 2001 62 69
3. V.S. Bankova, S.L. De Castro, and M.C. Marcucci Propolis recent advances in chemistry and plant origin Apidologie 31 2000 3 15
4. A.H. Banskota, Y. Tezuka, and S. Kadota Recent progress in pharmacological research of propolis Phytotherapy Research 15 2001 561 571
5. G.A. Burdock Review of the biological properties and toxicity of bee propolis (propolis) Food and Chemical Toxicology 36 1998 347 363
6. T.R. Burke Jr., M.R. Fesen, A. Mazumder, J. Wang, A.M. Carothers, D. Grunberger, J. Driscoll, K. Kohn, and Y. Pommier Hydroxylated aromatic inhibitors of HIV-1 integrase Journal of Medicinal Chemistry 38 1995 417 4178
7. M.M. Cowan Plant products as antimicrobial agents Clinical Microbiology Reviews 12 1999 564 582
8. J.W. Critchfield, S.T. Butera, and T.M. Folks Inhibition of HIV activation in latently infected cells by flavonoid compounds AIDS Research and Human Retroviruses 12 1996 39 46
9. E. De Clercq Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection Medicine Research Reviews 20 2000 323 349
10. + lymphocyte cultures Drug and Alcohol Dependence 64 2001 257 263
11. Z. Harish, A. Rubinstein, M. Golodner, M. Elmaliah, and Y. Mizrachi Suppression of HIV-1 replication by propolis and its immunoregulatory effect Drugs and Experimental Clinical Research 23 1997 89 96
12. J. Ito, F.R. Chang, H.K. Wang, Y.K. Park, M. Ikegaki, N. Kilgore, and K.H. Lee Anti-AIDS agents: 48 (1) anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis Journal of Natural Products 64 2001 1278 1281
13. Z.-G. Jiang, C. Piggee, M.P. Heyes, C. Murphy, B. Quearry, M. Bauer, J. Zheng, H.E. Gendelman, and S.P. Markey Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1 infected macrophages Journal of Neuroimmunology 117 2001 97 107
14. Kress, R., 1996. Value-Added Products from Beekeeping. FAO Agricultural Services Bulletin. Rome, Italy.
15. J.R. Lokensgard, G. Gekker, and P.K. Peterson Kappa-opioid receptor agonist inhibition of HIV-1 envelope glycoprotein-mediated membrane fusion and CXCR4 expression on CD4 (+) lymphocytes Biochemical Pharmacology 63 2002 1037 1041
16. O. Nussbaum, C.C. Broder, and E.A. Berger Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation Journal of Virology 68 1994 5411 5422
17. P.K. Peterson, G. Gekker, S. Hu, J. Lokensgard, P.S. Portoghese, and C.C. Chao Endomorphin-1 potentiates HIV-1 expression in human brain cell cultures: implication of an atypical mu-opioid receptor Neuropharmacology 38 1999 273 278
18. S.C. Piscitelli, A.H. Burstein, D. Chaitt, R.M. Alfaro, and J. Falloon Indinavir concentrations and St. John's wort Lancet 355 2000 547 548
19. S.C. Piscitelli, A.H. Burstein, N. Welden, K.D. Gallicano, and J. Falloon The effect of garlic supplements on the pharmacokinetics of saquinavir Clinical Infectious Diseases 34 2002 234 238
20. F.A. Santos, E.M.A.F. Bastos, A.B.R.A. Maia, M. Uzeda, M.A.R. Carvalho, L.M. Farias, and E.S.A. Morreira Brazilian propolis: physicochemical properties, plant origin and antibacterial activity of perodontopathogenes Phytotherapy Research 17 2003 285 289
21. J. Serkedjieva, N. Manolova, and V. Bankova Anti-influenza virus effect of some propolis constituents and their analogues (esters of substituted cinnamic acids) Journal of Natural Products 55 1992 294 302
22. T.S. Stantchev, and C.C. Broder Consistent and significant inhibition of human immunodeficiency virus type 1 envelope-mediated membrane fusion by beta-chemokines (RANTES) in primary human macrophages Journal of Infectious Diseases 182 2000 68 78
23. N. Vynograd, I. Vynograd, and Z. Sosnowski A comparative multi-centre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV) Phytomedicine 7 2000 1 6
24. H.K. Wang, Y. Xia, Z.Y. Yang, S.L. Natschke, and K.H. Lee Recent advances in the discovery and development of flavonoids and their analogues as antitumor and anti-HIV agents Advances in Experimental Medicine and Biology 439 1998 191 225
25. H.X. Xu, M. Wan, H. Dong, P.P. But, and L.Y. Foo Inhibitory activity of flavonoids and tannins against HIV-1 protease Biological Pharmacology Bulletin 23 2000 1072 1076