Heparin derivatives for the targeting of multiple activities in the inflammatory response

Carbohydrate Polymers

Volumn 117, Issue , 2015, Pages 400-407

  Veraldi, Noemi ^a   Hughes, Ashley J ^b,c   Rudd, Timothy R ^c   Thomas, Huw B ^b   Edwards, Steven W ^b   Hadfield, Lynsay ^d   Skidmore, Mark A ^b,d   Siligardi, Giuliano ^b,c   Cosentino, Cesare ^a   Shute, Janis K ^e   Naggi, Annamaria ^b   Yates, Edwin A ^b  

^a Istituto di Ricerche Chimiche e Biochimiche G Ronzoni   (Italy)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c DIAMOND LIGHT SOURCE LTD   (United Kingdom)

^d KEELE UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

Chemically modified heparin; Glycol split; IL 8; Inflammatory network; Neutrophil elastase; TNF alpha

Indexed keywords

DRUG PRODUCTS; GLYCOLS; PATHOLOGY;

ANTI-INFLAMMATORY AGENTS; ANTICOAGULANT ACTIVITIES; ANTICOAGULANT PROPERTIES; ATTRACTIVE STRATEGIES; CHEMICALLY MODIFIED; ELASTASE; IL-8; TNF-ALPHA;

POLYSACCHARIDES;

ANTICOAGULANT AGENT; HEPARIN; INTERLEUKIN 8; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INFLAMMATION; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTICOAGULANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPARIN; HUMANS; INFLAMMATION; INTERLEUKIN-8; LEUKOCYTE ELASTASE; PROTEINASE INHIBITORY PROTEINS, SECRETORY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84908284168     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2014.09.079     Document Type: Article

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