ONO-6818, a novel, potent neutrophil elastase inhibitor, reduces inflammatory mediators during simulated extracorporeal circulation

Annals of Thoracic Surgery

Volumn 76, Issue 4, 2003, Pages 1234-1239

  Yoshimura, Yukihiro ^b   Hiramatsu, Yuji ^a   Sato, Yukio ^b   Homma, Satoshi ^b   Enomoto, Yoshiharu ^b   Jikuya, Tomoaki ^b   Sakakibara, Yuzuru ^b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CELL ADHESION MOLECULE; CYTOPLASM PROTEIN; F ACTIN; INTERLEUKIN 8; L SELECTIN; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; ONO 6818; SILICON; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DRUG EFFECT; ENZYME BLOOD LEVEL; ENZYME IMMUNOASSAY; ENZYME INHIBITION; EXTRACORPOREAL CIRCULATION; FLOW CYTOMETRY; HEPARINIZATION; HUMAN; HUMAN CELL; INFLAMMATION; MICROCIRCULATION; MOLECULAR WEIGHT; NORMAL HUMAN; OXYGENATOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PUMP; SIMULATION;

ACTINS; ANTIGENS, CD11B; CARDIOPULMONARY BYPASS; COMPLEMENT MEMBRANE ATTACK COMPLEX; EXTRACORPOREAL CIRCULATION; FLOW CYTOMETRY; HUMANS; IMMUNOENZYME TECHNIQUES; INTERLEUKIN-8; L-SELECTIN; LEUKOCYTE ELASTASE; MODELS, BIOLOGICAL; OXADIAZOLES; PYRIMIDINONES;

EID: 0141563253     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(03)00878-6     Document Type: Article

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